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The map label for this gene is infC [H]

Identifier: 162147244

GI number: 162147244

Start: 1453184

End: 1453705

Strand: Direct

Name: infC [H]

Synonym: GDI_1449

Alternate gene names: 162147244

Gene position: 1453184-1453705 (Clockwise)

Preceding gene: 162147243

Following gene: 162147254

Centisome position: 36.84

GC content: 60.54

Gene sequence:

>522_bases
ATGCCCACTCCGCCTAACCGCGAGGGCCCACGCGTCAACGAGGAAATTCGTGTCCCGCAGGTGCGTCTGATCGACGCGGA
CGGCGAGATGCTGGGCGTCATGCCCACACGCGACGCGCTGATGCGCGCTTATGCGGTCGGTCTCGACCTGCTGGAAATCA
GTCCGAACGCCGAACCCCCGGTCGCCAAGATCCTGGATTACGGCAAGTTCAAGTACGAACAGCAGAAAAAGCGCAACGAG
GCCCGCAAGAAGCAGAAGGTCATCGAGATCAAGGAGGTCAAGGTCCGGCCGAATATCGATGAGAACGACTATCAGGTGAA
GATGCGCGCCATGAAGTCGTTCATCGGCGAGGGCGACAAGGTCAAGGTGACGCTGCGCTTCCGTGGCCGCGAAATGGCGC
ACCAGGACCTGGGCATCAAGGTCCTGGAACGCATCCGCACCGAGATGGACGAACAGGCGAAGGTCGAGCAGATGCCCAAG
CTCGAAAACCGCCAGATGATCATGGTCCTGTCGCCCCGTTGA

Upstream 100 bases:

>100_bases
ATTTGCGCTGTCTCGACCCCATTGCCCGCGGGCAGTGGCGGGGGTGGTGCGCTCTCCGGGGCGAAAACGAAGACAGGAGC
CGACCATAGCCAGACCTCCG

Downstream 100 bases:

>100_bases
CCCCGGCAGGGCCTGGAACGAAAAAAGCCCGGACCCTGGTCCGGGCTTTTTTTTATTTACGCGCCCGCATCACGGTCGCC
GTCACGCGCTGGTGGGGCCT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MPTPPNREGPRVNEEIRVPQVRLIDADGEMLGVMPTRDALMRAYAVGLDLLEISPNAEPPVAKILDYGKFKYEQQKKRNE
ARKKQKVIEIKEVKVRPNIDENDYQVKMRAMKSFIGEGDKVKVTLRFRGREMAHQDLGIKVLERIRTEMDEQAKVEQMPK
LENRQMIMVLSPR

Sequences:

>Translated_173_residues
MPTPPNREGPRVNEEIRVPQVRLIDADGEMLGVMPTRDALMRAYAVGLDLLEISPNAEPPVAKILDYGKFKYEQQKKRNE
ARKKQKVIEIKEVKVRPNIDENDYQVKMRAMKSFIGEGDKVKVTLRFRGREMAHQDLGIKVLERIRTEMDEQAKVEQMPK
LENRQMIMVLSPR
>Mature_172_residues
PTPPNREGPRVNEEIRVPQVRLIDADGEMLGVMPTRDALMRAYAVGLDLLEISPNAEPPVAKILDYGKFKYEQQKKRNEA
RKKQKVIEIKEVKVRPNIDENDYQVKMRAMKSFIGEGDKVKVTLRFRGREMAHQDLGIKVLERIRTEMDEQAKVEQMPKL
ENRQMIMVLSPR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=57.9268292682927, Blast_Score=181, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20099; Mature: 19968

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTPPNREGPRVNEEIRVPQVRLIDADGEMLGVMPTRDALMRAYAVGLDLLEISPNAEPP
CCCCCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHCCEEEEECCCCCCC
VAKILDYGKFKYEQQKKRNEARKKQKVIEIKEVKVRPNIDENDYQVKMRAMKSFIGEGDK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCE
VKVTLRFRGREMAHQDLGIKVLERIRTEMDEQAKVEQMPKLENRQMIMVLSPR
EEEEEEECCCHHHHHHCCHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEECCC
>Mature Secondary Structure 
PTPPNREGPRVNEEIRVPQVRLIDADGEMLGVMPTRDALMRAYAVGLDLLEISPNAEPP
CCCCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHCCEEEEECCCCCCC
VAKILDYGKFKYEQQKKRNEARKKQKVIEIKEVKVRPNIDENDYQVKMRAMKSFIGEGDK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCE
VKVTLRFRGREMAHQDLGIKVLERIRTEMDEQAKVEQMPKLENRQMIMVLSPR
EEEEEEECCCHHHHHHCCHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA