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The map label for this gene is murA

Identifier: 162147237

GI number: 162147237

Start: 1445090

End: 1446352

Strand: Reverse

Name: murA

Synonym: GDI_1442

Alternate gene names: 162147237

Gene position: 1446352-1445090 (Counterclockwise)

Preceding gene: 162147238

Following gene: 162147236

Centisome position: 36.67

GC content: 70.39

Gene sequence:

>1263_bases
ATGGACCGTTTCATCATTCACGGCGGCCACCGGCTGCGCGGCGACATCGTCATCGGCGGCGCCAAGAACGCGGCGCTGAA
GCTGCTGGTCGCGGGGCTGCTGACCTCCGAACGGCTGGTGCTGCGCAACGTGCCGCGCATCGCGGACATCACGACCATGC
GCCGGCTGCTGGAACAGCACGGGGTCACGGTCGAGGACCTGGAGGGCGACGGCGGCACCCTGGCCGTCGGCGGCACCATC
ACGAACACCGAGGCCCCATACGACATCGTGTCGCAGATGCGCGCCTCGATCCTGGTGCTGGGCCCGCTGCTGGCGCGCTG
CGGCGAGGCCCGGGTGTCCCTGCCCGGCGGCTGCGCCATCGGCACCCGCCCGGTGGACATGCACCTGAAGGGGCTGGAGG
CGCTGGGCGCCGAGATCTCGCTGGAAAACGGGTATATCAACGCCCGCGCGCCGCGCGGGCTGGTGGGCGAACGCATCATC
CTGCCGTTCGCCTCGGTCGGCGCCACGGAAAACCTGCTGATGGCGTCCTGCCTGGCACGCGGGCGGACCGAGATCATCAA
TGCGGCGCGCGAGCCGGAGATCGCGGACCTGGTCGCCTGCCTGAACGGCATGGGCGCGCGCATCACCGGCACGGGTACCG
GCTCGCTGGCCATCGAAGGGGTCGAGGCGCTGCACGGCACGACCCACCGCGTGATGCCCGACCGGATCGAATGCGGCACC
TATGCCTGCGCCGCCGGGATCACGGGCGGCGAGCTGCGGCTGATCGGCGGCCGGGCCGACCATCTGGGCGCGGTGGTCCG
CGCGCTGGAGGAAGCCGGGGTCGAGGTGTTCCAGGAGGACGACGCCCTGCGCGTGCGCCGCACCGGGGCGCTGCGCGGCG
TGGACATCATGACCGAGCCCTATCCCGGCTTTCCCACCGACATGCAGGCGCAGTTCATGGCCCTGCTGTCGGTCGCCGAG
GGCGCGTCGATGGTCACCGAGACCATCTTCGAAAACCGGTTCATGCACGTGCCGGAACTGAACCGCATGGGCGCGCGCAT
CAACGTCCATGGTTCGTCCGCGATCATTCGCGGCGTGCATTCGCTGTCGGGCGCGCCGGTGATGGCGACCGACCTGCGGG
CCTCGTTCTCGCTGATCCTGGCGGGGCTGGCAGCGCATGGCGAGACGATCCTGAGCCGCGTCTATCACTTGGACCGGGGC
TACGAGGCCGTGGAACAGAAGCTGGCGCGCTGCGGCGCGCAGATCGAGCGCGTTCGGGAATGA

Upstream 100 bases:

>100_bases
TTCCAGGGCGCGTCGCCGTGCGAGGTCAGCTATGCCGACCGGGCGGGCAAATATATGGGACAGCGCGGCGTCGCGACCCC
ACGGATGTAGGAGCCCGGCC

Downstream 100 bases:

>100_bases
TGCGGCGCGCGCCCTTCCTGCGGCGGGGCGGAATGTGATAAGGCGCAGCCCACATGGCGCCTGGCCGGTATCGCATGGGG
CGCGCGTTTTGTAGCTGGAG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MDRFIIHGGHRLRGDIVIGGAKNAALKLLVAGLLTSERLVLRNVPRIADITTMRRLLEQHGVTVEDLEGDGGTLAVGGTI
TNTEAPYDIVSQMRASILVLGPLLARCGEARVSLPGGCAIGTRPVDMHLKGLEALGAEISLENGYINARAPRGLVGERII
LPFASVGATENLLMASCLARGRTEIINAAREPEIADLVACLNGMGARITGTGTGSLAIEGVEALHGTTHRVMPDRIECGT
YACAAGITGGELRLIGGRADHLGAVVRALEEAGVEVFQEDDALRVRRTGALRGVDIMTEPYPGFPTDMQAQFMALLSVAE
GASMVTETIFENRFMHVPELNRMGARINVHGSSAIIRGVHSLSGAPVMATDLRASFSLILAGLAAHGETILSRVYHLDRG
YEAVEQKLARCGAQIERVRE

Sequences:

>Translated_420_residues
MDRFIIHGGHRLRGDIVIGGAKNAALKLLVAGLLTSERLVLRNVPRIADITTMRRLLEQHGVTVEDLEGDGGTLAVGGTI
TNTEAPYDIVSQMRASILVLGPLLARCGEARVSLPGGCAIGTRPVDMHLKGLEALGAEISLENGYINARAPRGLVGERII
LPFASVGATENLLMASCLARGRTEIINAAREPEIADLVACLNGMGARITGTGTGSLAIEGVEALHGTTHRVMPDRIECGT
YACAAGITGGELRLIGGRADHLGAVVRALEEAGVEVFQEDDALRVRRTGALRGVDIMTEPYPGFPTDMQAQFMALLSVAE
GASMVTETIFENRFMHVPELNRMGARINVHGSSAIIRGVHSLSGAPVMATDLRASFSLILAGLAAHGETILSRVYHLDRG
YEAVEQKLARCGAQIERVRE
>Mature_420_residues
MDRFIIHGGHRLRGDIVIGGAKNAALKLLVAGLLTSERLVLRNVPRIADITTMRRLLEQHGVTVEDLEGDGGTLAVGGTI
TNTEAPYDIVSQMRASILVLGPLLARCGEARVSLPGGCAIGTRPVDMHLKGLEALGAEISLENGYINARAPRGLVGERII
LPFASVGATENLLMASCLARGRTEIINAAREPEIADLVACLNGMGARITGTGTGSLAIEGVEALHGTTHRVMPDRIECGT
YACAAGITGGELRLIGGRADHLGAVVRALEEAGVEVFQEDDALRVRRTGALRGVDIMTEPYPGFPTDMQAQFMALLSVAE
GASMVTETIFENRFMHVPELNRMGARINVHGSSAIIRGVHSLSGAPVMATDLRASFSLILAGLAAHGETILSRVYHLDRG
YEAVEQKLARCGAQIERVRE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=421, Percent_Identity=50.1187648456057, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_GLUDA (A9HFN0)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001601698.1
- RefSeq:   YP_002276515.1
- ProteinModelPortal:   A9HFN0
- SMR:   A9HFN0
- GeneID:   5791560
- GeneID:   6975570
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_2142
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44570; Mature: 44570

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRFIIHGGHRLRGDIVIGGAKNAALKLLVAGLLTSERLVLRNVPRIADITTMRRLLEQH
CCCEEEECCCEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHC
GVTVEDLEGDGGTLAVGGTITNTEAPYDIVSQMRASILVLGPLLARCGEARVSLPGGCAI
CCEEEEECCCCCEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
GTRPVDMHLKGLEALGAEISLENGYINARAPRGLVGERIILPFASVGATENLLMASCLAR
CCCCHHHHHHHHHHCCCEEEECCCEEECCCCCCCCCCEEEEEEHHCCCCHHHHHHHHHHC
GRTEIINAAREPEIADLVACLNGMGARITGTGTGSLAIEGVEALHGTTHRVMPDRIECGT
CHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCEEECCHHHHCCCCCCCCCCCCCCCC
YACAAGITGGELRLIGGRADHLGAVVRALEEAGVEVFQEDDALRVRRTGALRGVDIMTEP
CHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCHHEECCCCCEEEECCCCCCCCEEECCC
YPGFPTDMQAQFMALLSVAEGASMVTETIFENRFMHVPELNRMGARINVHGSSAIIRGVH
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCHHHHHHHH
SLSGAPVMATDLRASFSLILAGLAAHGETILSRVYHLDRGYEAVEQKLARCGAQIERVRE
HCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDRFIIHGGHRLRGDIVIGGAKNAALKLLVAGLLTSERLVLRNVPRIADITTMRRLLEQH
CCCEEEECCCEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHC
GVTVEDLEGDGGTLAVGGTITNTEAPYDIVSQMRASILVLGPLLARCGEARVSLPGGCAI
CCEEEEECCCCCEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
GTRPVDMHLKGLEALGAEISLENGYINARAPRGLVGERIILPFASVGATENLLMASCLAR
CCCCHHHHHHHHHHCCCEEEECCCEEECCCCCCCCCCEEEEEEHHCCCCHHHHHHHHHHC
GRTEIINAAREPEIADLVACLNGMGARITGTGTGSLAIEGVEALHGTTHRVMPDRIECGT
CHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCEEECCHHHHCCCCCCCCCCCCCCCC
YACAAGITGGELRLIGGRADHLGAVVRALEEAGVEVFQEDDALRVRRTGALRGVDIMTEP
CHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCHHEECCCCCEEEECCCCCCCCEEECCC
YPGFPTDMQAQFMALLSVAEGASMVTETIFENRFMHVPELNRMGARINVHGSSAIIRGVH
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCHHHHHHHH
SLSGAPVMATDLRASFSLILAGLAAHGETILSRVYHLDRGYEAVEQKLARCGAQIERVRE
HCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA