Click here to switch to the map view.

The map label for this gene is asd [H]

Identifier: 162147202

GI number: 162147202

Start: 1408544

End: 1409572

Strand: Reverse

Name: asd [H]

Synonym: GDI_1407

Alternate gene names: 162147202

Gene position: 1409572-1408544 (Counterclockwise)

Preceding gene: 162147205

Following gene: 162147201

Centisome position: 35.74

GC content: 65.21

Gene sequence:

>1029_bases
ATGGGATACCGCGTTGCGGTCGTCGGCGCCACGGGCGCCGTCGGGCGGGAAATGCTCAAGACGCTGGCCGAACGCGCGTT
TCCGATAGACGAGATCGTCGCCCTGGCCTCGGCCCGATCGGCGGGGCAGGAGGTCTCGTTCGGCGACAAGACGGTGCTGA
AGGTGCAGAACCTGGAGCATTTCGACTTCACCGGCTGGGACATCGCCCTGTTCTCGCCCGGGGCGTCGGTTTCGGCGGTG
CATGCGCCGCGCGCGGCCAAGGCCGGATGCATCGTCATCGACAACACGTCGCATTTCCGCATGGAACACGACGTGCCGCT
GGTGGTGCCCGAGGTCAACCCGAACGCGCTAAAGCGGGCGCGGCGCGGCATCATCGCCAACCCGAACTGCTCGACCATCC
AGATGGTGGTGGCGCTGAAGCCGCTGCACGACCTGTTCACCATCCGCCGCGTCGTGGTGGCCACGTACCAGGCGGTGGCC
GGCGCGGGCAAGGAAGGCATGGACGAACTGTTCGCCCAGTCGCGCGCCAGCTTCGTGGGCGACCCGCTGAAGGCCGAACA
GTTCACCAAGCAGATCGCCTTCAACTGCATTCCCCATATCGACCGTTTCATGGATGACGGCGCGACCAAGGAGGAATGGA
AGATGACGGTCGAGACCCGCAAAATCCTTGACCCTGACATCTCGGTTTTCGCTACCTGCGTGCGCGTGCCGGTCTTCATC
GGCCATTCCGAGGCCATCACGGTCGAGTTCGAGGAACCCGTGGACCTGGAGCGCGCGCGGGAGGCCCTGCGCGAGGCGCC
GGGCGTCATCCTGCACGACCAGCGCGAGGATGGCGGCTACGTCACGCCGACAGAATGTGTTGGTGAGGACGCAACTTACG
TGTCGCGCCTGCGGATCGACCCGACCGTACCCAACGGCCTGGCCTTCTGGTGCGTGGCGGACAATCTGCGCAAAGGGGCC
GCGCTGAATGCAGTACAGATCGCGGAAACCATGATCGCGCTGGACCTGATTCACCACAAGGCCACCTGA

Upstream 100 bases:

>100_bases
TTGCATAGCACCCGGGACGGCACTACCTGTCAGCGTCTCCAATCAGGAGAAAACACGCAGCCCCCGGGCAGGCCGGGCGC
GCAGATCAGGGAATGGATCG

Downstream 100 bases:

>100_bases
TCGACACCACGAAAAACCGGAACGGTACGAAATCGTTCCGGTTGCGTGCCACGGCACTGCAATCACGCGTCTCGCGACCT
CGTGTTCCCCCCTGCGTTGA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MGYRVAVVGATGAVGREMLKTLAERAFPIDEIVALASARSAGQEVSFGDKTVLKVQNLEHFDFTGWDIALFSPGASVSAV
HAPRAAKAGCIVIDNTSHFRMEHDVPLVVPEVNPNALKRARRGIIANPNCSTIQMVVALKPLHDLFTIRRVVVATYQAVA
GAGKEGMDELFAQSRASFVGDPLKAEQFTKQIAFNCIPHIDRFMDDGATKEEWKMTVETRKILDPDISVFATCVRVPVFI
GHSEAITVEFEEPVDLERAREALREAPGVILHDQREDGGYVTPTECVGEDATYVSRLRIDPTVPNGLAFWCVADNLRKGA
ALNAVQIAETMIALDLIHHKAT

Sequences:

>Translated_342_residues
MGYRVAVVGATGAVGREMLKTLAERAFPIDEIVALASARSAGQEVSFGDKTVLKVQNLEHFDFTGWDIALFSPGASVSAV
HAPRAAKAGCIVIDNTSHFRMEHDVPLVVPEVNPNALKRARRGIIANPNCSTIQMVVALKPLHDLFTIRRVVVATYQAVA
GAGKEGMDELFAQSRASFVGDPLKAEQFTKQIAFNCIPHIDRFMDDGATKEEWKMTVETRKILDPDISVFATCVRVPVFI
GHSEAITVEFEEPVDLERAREALREAPGVILHDQREDGGYVTPTECVGEDATYVSRLRIDPTVPNGLAFWCVADNLRKGA
ALNAVQIAETMIALDLIHHKAT
>Mature_341_residues
GYRVAVVGATGAVGREMLKTLAERAFPIDEIVALASARSAGQEVSFGDKTVLKVQNLEHFDFTGWDIALFSPGASVSAVH
APRAAKAGCIVIDNTSHFRMEHDVPLVVPEVNPNALKRARRGIIANPNCSTIQMVVALKPLHDLFTIRRVVVATYQAVAG
AGKEGMDELFAQSRASFVGDPLKAEQFTKQIAFNCIPHIDRFMDDGATKEEWKMTVETRKILDPDISVFATCVRVPVFIG
HSEAITVEFEEPVDLERAREALREAPGVILHDQREDGGYVTPTECVGEDATYVSRLRIDPTVPNGLAFWCVADNLRKGAA
LNAVQIAETMIALDLIHHKAT

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=40.0593471810089, Blast_Score=227, Evalue=7e-61,
Organism=Escherichia coli, GI1789841, Length=354, Percent_Identity=27.4011299435028, Blast_Score=97, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=404, Percent_Identity=29.2079207920792, Blast_Score=94, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37329; Mature: 37198

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYRVAVVGATGAVGREMLKTLAERAFPIDEIVALASARSAGQEVSFGDKTVLKVQNLEH
CCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
FDFTGWDIALFSPGASVSAVHAPRAAKAGCIVIDNTSHFRMEHDVPLVVPEVNPNALKRA
CCCCCEEEEEECCCCCCEEEECCCCCCCCEEEEECCCCEEEECCCCEEEECCCHHHHHHH
RRGIIANPNCSTIQMVVALKPLHDLFTIRRVVVATYQAVAGAGKEGMDELFAQSRASFVG
HCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
DPLKAEQFTKQIAFNCIPHIDRFMDDGATKEEWKMTVETRKILDPDISVFATCVRVPVFI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEHHHHHHCCCCHHHHHHHHHHHEEE
GHSEAITVEFEEPVDLERAREALREAPGVILHDQREDGGYVTPTECVGEDATYVSRLRID
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCEECCHHHCCCCCHHHEEEEEC
PTVPNGLAFWCVADNLRKGAALNAVQIAETMIALDLIHHKAT
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GYRVAVVGATGAVGREMLKTLAERAFPIDEIVALASARSAGQEVSFGDKTVLKVQNLEH
CEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
FDFTGWDIALFSPGASVSAVHAPRAAKAGCIVIDNTSHFRMEHDVPLVVPEVNPNALKRA
CCCCCEEEEEECCCCCCEEEECCCCCCCCEEEEECCCCEEEECCCCEEEECCCHHHHHHH
RRGIIANPNCSTIQMVVALKPLHDLFTIRRVVVATYQAVAGAGKEGMDELFAQSRASFVG
HCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
DPLKAEQFTKQIAFNCIPHIDRFMDDGATKEEWKMTVETRKILDPDISVFATCVRVPVFI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEHHHHHHCCCCHHHHHHHHHHHEEE
GHSEAITVEFEEPVDLERAREALREAPGVILHDQREDGGYVTPTECVGEDATYVSRLRID
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCEECCHHHCCCCCHHHEEEEEC
PTVPNGLAFWCVADNLRKGAALNAVQIAETMIALDLIHHKAT
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]