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The map label for this gene is sdhB [H]

Identifier: 162147198

GI number: 162147198

Start: 1404728

End: 1405510

Strand: Reverse

Name: sdhB [H]

Synonym: GDI_1403

Alternate gene names: 162147198

Gene position: 1405510-1404728 (Counterclockwise)

Preceding gene: 162147199

Following gene: 162147197

Centisome position: 35.64

GC content: 63.6

Gene sequence:

>783_bases
ATGGTCGAATTCAGCCTGCCAAAGAACAGCCAGATCGGGAAAGGCCGTATTTTCACGGCCGCACCCGGCGCCAAGAACGT
CAAGCCGTTCCGGGTCTATCGCTGGAACCCGGACGACGGTGCCAACCCCGTCGTCGACACCTACGAGATCGATCTGGATA
CGATCGGCCCGATGGTGCTGGACGCGCTGATCCACATCAAGAACAACGTCGATCCGACGCTGACCTTCCGCCGGTCCTGC
CGCGAGGGGATCTGCGGGTCGTGCGCCATGAACATCGACGGCGAAAACACGCTTGCGTGCCTGAAGCCGATCAAGGACGT
GCATGACGCGGTGTCGATCTATCCGCTGCCGCACATGCCGGTCGTCAAGGACCTGGTGCCCGACCTGAACGGCGCCTATG
CCCAGCTTCGCTCGATCGAGCCCTGGCTGAAATCCGATACGGCGCCCCCGCCGGATTCGGAGCGCCGCCAGAGCATCGAG
GAACGTGCGGAACTGGACGGGATGTGGGAATGCATCCTGTGCTTCTGCTGCACCACGTCCTGCCCGTCCTACTGGTGGAA
CGGCGACCGGTACCTGGGCCCGGCCACCCTGCTGGCGGCCTATCGCTGGATCGCCGACAGCCGTGACGAACATGCGGGCG
AGCGGCTGGATGCGCTGGAAGATCCGCTGAAGCTGTATGCCTGCCGCACGATCATGAACTGCACCCAGACCTGCCCCAAG
GGCCTGAACCCGGCGAAGGCCATCGCCCGGATCAAGGAACTGCAGCTGGAACGCAAGATCTGA

Upstream 100 bases:

>100_bases
CTACCGCCCGGTGCACATGAAGACGCTGACCGACGAGGTCCAGGTCTTCCCCCCCAAAAAGCGCGTCTACTAAGCGAAGC
GGCGGAAAAGGGACGAGACG

Downstream 100 bases:

>100_bases
TCCCGCGCCGCCGGGCAAGCCGGCGGATGCGACCGACTGAAATGATTGACGGACAGGGCGCCGGATGGGACACATCCGAC
GCCCTTTCTTTTTGCCCCCT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MVEFSLPKNSQIGKGRIFTAAPGAKNVKPFRVYRWNPDDGANPVVDTYEIDLDTIGPMVLDALIHIKNNVDPTLTFRRSC
REGICGSCAMNIDGENTLACLKPIKDVHDAVSIYPLPHMPVVKDLVPDLNGAYAQLRSIEPWLKSDTAPPPDSERRQSIE
ERAELDGMWECILCFCCTTSCPSYWWNGDRYLGPATLLAAYRWIADSRDEHAGERLDALEDPLKLYACRTIMNCTQTCPK
GLNPAKAIARIKELQLERKI

Sequences:

>Translated_260_residues
MVEFSLPKNSQIGKGRIFTAAPGAKNVKPFRVYRWNPDDGANPVVDTYEIDLDTIGPMVLDALIHIKNNVDPTLTFRRSC
REGICGSCAMNIDGENTLACLKPIKDVHDAVSIYPLPHMPVVKDLVPDLNGAYAQLRSIEPWLKSDTAPPPDSERRQSIE
ERAELDGMWECILCFCCTTSCPSYWWNGDRYLGPATLLAAYRWIADSRDEHAGERLDALEDPLKLYACRTIMNCTQTCPK
GLNPAKAIARIKELQLERKI
>Mature_260_residues
MVEFSLPKNSQIGKGRIFTAAPGAKNVKPFRVYRWNPDDGANPVVDTYEIDLDTIGPMVLDALIHIKNNVDPTLTFRRSC
REGICGSCAMNIDGENTLACLKPIKDVHDAVSIYPLPHMPVVKDLVPDLNGAYAQLRSIEPWLKSDTAPPPDSERRQSIE
ERAELDGMWECILCFCCTTSCPSYWWNGDRYLGPATLLAAYRWIADSRDEHAGERLDALEDPLKLYACRTIMNCTQTCPK
GLNPAKAIARIKELQLERKI

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=244, Percent_Identity=64.344262295082, Blast_Score=323, Evalue=1e-88,
Organism=Escherichia coli, GI1786943, Length=233, Percent_Identity=49.3562231759657, Blast_Score=244, Evalue=5e-66,
Organism=Escherichia coli, GI1790596, Length=228, Percent_Identity=32.8947368421053, Blast_Score=136, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17533915, Length=231, Percent_Identity=61.4718614718615, Blast_Score=304, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6322987, Length=229, Percent_Identity=59.825327510917, Blast_Score=294, Evalue=8e-81,
Organism=Drosophila melanogaster, GI17137106, Length=234, Percent_Identity=61.5384615384615, Blast_Score=317, Evalue=4e-87,
Organism=Drosophila melanogaster, GI24643156, Length=231, Percent_Identity=60.1731601731602, Blast_Score=293, Evalue=1e-79,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29152; Mature: 29152

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEFSLPKNSQIGKGRIFTAAPGAKNVKPFRVYRWNPDDGANPVVDTYEIDLDTIGPMVL
CCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCEEEEECHHHHHHHHH
DALIHIKNNVDPTLTFRRSCREGICGSCAMNIDGENTLACLKPIKDVHDAVSIYPLPHMP
HHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHEECCCCCCC
VVKDLVPDLNGAYAQLRSIEPWLKSDTAPPPDSERRQSIEERAELDGMWECILCFCCTTS
HHHHHHCCCCHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
CPSYWWNGDRYLGPATLLAAYRWIADSRDEHAGERLDALEDPLKLYACRTIMNCTQTCPK
CCCCCCCCCCEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLNPAKAIARIKELQLERKI
CCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVEFSLPKNSQIGKGRIFTAAPGAKNVKPFRVYRWNPDDGANPVVDTYEIDLDTIGPMVL
CCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCEEEEECHHHHHHHHH
DALIHIKNNVDPTLTFRRSCREGICGSCAMNIDGENTLACLKPIKDVHDAVSIYPLPHMP
HHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHEECCCCCCC
VVKDLVPDLNGAYAQLRSIEPWLKSDTAPPPDSERRQSIEERAELDGMWECILCFCCTTS
HHHHHHCCCCHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
CPSYWWNGDRYLGPATLLAAYRWIADSRDEHAGERLDALEDPLKLYACRTIMNCTQTCPK
CCCCCCCCCCEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLNPAKAIARIKELQLERKI
CCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA