Click here to switch to the map view.

The map label for this gene is tadA [H]

Identifier: 162147097

GI number: 162147097

Start: 1301753

End: 1302334

Strand: Direct

Name: tadA [H]

Synonym: GDI_1302

Alternate gene names: 162147097

Gene position: 1301753-1302334 (Clockwise)

Preceding gene: 162147091

Following gene: 162147098

Centisome position: 33.0

GC content: 74.4

Gene sequence:

>582_bases
TTGCACGCCGGGGCCCGGTTTTTCGCCATTTTCGGGACAGGTGTCATGACGAACGGGGCCGCGAGAGGCCAGGCCGGCGA
CGGCCCGATGGCCCTGGCGCTGGCCGAGGCCCGCGCCGCCGCCGCCCGGGGCGAGGTTCCGGTGGGGGCCGTGCTGCTGG
GCCCGGACGGCACTATCCTGGCGCGGGCCGGCAACCAGGTGGAAGCCGGGCATGACGCGGCGGCCCATGCCGAAATGCTG
GTCATGCGCGCCGCCGCCCGCATCCTGGGCAGTCCGCGCCTGACCGGCTGCACGCTGGTCGTGACGCTGGAGCCCTGCCC
GATGTGCGCGGCGGCTTCGGTGCATTTCCGCGTGGGGCGTATCGTGTTCGGCGCCTACGACCCCAAGGGCGGCGGGGTCG
AGCACGGGCCACGGCTGCTGGCGCGGCCGGACTGCCTGCATCGCCCCGAATGGGTGGGCGGCGTGCGCGAGCGCGAGGCG
GCGGCCCTGCTGCGCGATTTCTTCGCGGCCCTGCGCGGCAGGCCGGAAGGCGGGCCGCCTGAAGGGGACGGGAAGGGGGA
TTTGCGGGAAGCGTCCAGTTAA

Upstream 100 bases:

>100_bases
CGTGAGGCACTGTAACATGTTGTGATGACGGGACCTTCGCCGGCGTGCGGGCATTTCACCCCGCCTGCGGTATGGATCGA
ACGGTCCGACGGCAGGCGGG

Downstream 100 bases:

>100_bases
CGCATCTTTCATCGGCAGGTATGGGAGAGGTGTGGCCCACCGGTGCATTCTCCCGGACGATGACACAGGATGCGGGGCGG
ACCACTCCGGTCGCCCCGGA

Product: cytidine deaminase protein

Products: uracil; NH3

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MHAGARFFAIFGTGVMTNGAARGQAGDGPMALALAEARAAAARGEVPVGAVLLGPDGTILARAGNQVEAGHDAAAHAEML
VMRAAARILGSPRLTGCTLVVTLEPCPMCAAASVHFRVGRIVFGAYDPKGGGVEHGPRLLARPDCLHRPEWVGGVREREA
AALLRDFFAALRGRPEGGPPEGDGKGDLREASS

Sequences:

>Translated_193_residues
MHAGARFFAIFGTGVMTNGAARGQAGDGPMALALAEARAAAARGEVPVGAVLLGPDGTILARAGNQVEAGHDAAAHAEML
VMRAAARILGSPRLTGCTLVVTLEPCPMCAAASVHFRVGRIVFGAYDPKGGGVEHGPRLLARPDCLHRPEWVGGVREREA
AALLRDFFAALRGRPEGGPPEGDGKGDLREASS
>Mature_193_residues
MHAGARFFAIFGTGVMTNGAARGQAGDGPMALALAEARAAAARGEVPVGAVLLGPDGTILARAGNQVEAGHDAAAHAEML
VMRAAARILGSPRLTGCTLVVTLEPCPMCAAASVHFRVGRIVFGAYDPKGGGVEHGPRLLARPDCLHRPEWVGGVREREA
AALLRDFFAALRGRPEGGPPEGDGKGDLREASS

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=139, Percent_Identity=43.1654676258993, Blast_Score=100, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6322425, Length=159, Percent_Identity=31.4465408805031, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355527, Length=167, Percent_Identity=37.7245508982036, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.1

Molecular weight: Translated: 19794; Mature: 19794

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAGARFFAIFGTGVMTNGAARGQAGDGPMALALAEARAAAARGEVPVGAVLLGPDGTIL
CCCCCEEEEEECCCEEECCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEEECCCCEEE
ARAGNQVEAGHDAAAHAEMLVMRAAARILGSPRLTGCTLVVTLEPCPMCAAASVHFRVGR
EECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHEEEEEEE
IVFGAYDPKGGGVEHGPRLLARPDCLHRPEWVGGVREREAAALLRDFFAALRGRPEGGPP
EEEEEECCCCCCCCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCC
EGDGKGDLREASS
CCCCCCCCCCCCC
>Mature Secondary Structure
MHAGARFFAIFGTGVMTNGAARGQAGDGPMALALAEARAAAARGEVPVGAVLLGPDGTIL
CCCCCEEEEEECCCEEECCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEEECCCCEEE
ARAGNQVEAGHDAAAHAEMLVMRAAARILGSPRLTGCTLVVTLEPCPMCAAASVHFRVGR
EECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHEEEEEEE
IVFGAYDPKGGGVEHGPRLLARPDCLHRPEWVGGVREREAAALLRDFFAALRGRPEGGPP
EEEEEECCCCCCCCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCC
EGDGKGDLREASS
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cytosine; H2O

Specific reaction: cytosine + H2O = uracil + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]