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The map label for this gene is atpE

Identifier: 162146974

GI number: 162146974

Start: 1175804

End: 1176028

Strand: Reverse

Name: atpE

Synonym: GDI_1179

Alternate gene names: 162146974

Gene position: 1176028-1175804 (Counterclockwise)

Preceding gene: 162146975

Following gene: 162146973

Centisome position: 29.82

GC content: 64.89

Gene sequence:

>225_bases
ATGGACATCGCTGCAGCCCGGGAAATTGGTGCCGGTATCGCCGTTATCGCCCTCGCCGGCGTCGGCATCGGCCTGGGTAA
CATCTTCTCCACGCTGGTCAGCAGCATCGCCCGCAATCCGGCCGCGCGTCCGCACGTGTTCGGCCTGGGCATGCTGGGCT
TCGCCCTGACGGAAGCCGTTGCCCTGTACGCCCTGCTCATCGCCTTCCTGATCCTGTTCGTCTAA

Upstream 100 bases:

>100_bases
GCCATTCTCACCTGCATCTACCTGCGGGAGGCGGTCGCGCACTGATCGCGACGTATCCCCAGCCTCTTTGAACGCCTGAA
CAACCAAGGAAAGCCTCGCT

Downstream 100 bases:

>100_bases
GAACGGAGGCCGAAATGGCACGTTCCGCGGTGTCGATCACCCGCAAGGCGGCGTCGCTCCTGACGTCGTCCGCGCTGGCC
CTGCCCGTTATGGCGATGGC

Product: ATP synthase

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(0) sector subunit c; F-type ATPase subunit c; F-ATPase subunit c; Lipid-binding protein

Number of amino acids: Translated: 74; Mature: 74

Protein sequence:

>74_residues
MDIAAAREIGAGIAVIALAGVGIGLGNIFSTLVSSIARNPAARPHVFGLGMLGFALTEAVALYALLIAFLILFV

Sequences:

>Translated_74_residues
MDIAAAREIGAGIAVIALAGVGIGLGNIFSTLVSSIARNPAARPHVFGLGMLGFALTEAVALYALLIAFLILFV
>Mature_74_residues
MDIAAAREIGAGIAVIALAGVGIGLGNIFSTLVSSIARNPAARPHVFGLGMLGFALTEAVALYALLIAFLILFV

Specific function: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits

COG id: COG0636

COG function: function code C; F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase C chain family

Homologues:

Organism=Homo sapiens, GI4502301, Length=69, Percent_Identity=49.2753623188406, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI50659074, Length=69, Percent_Identity=49.2753623188406, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI50593533, Length=69, Percent_Identity=49.2753623188406, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI50659069, Length=69, Percent_Identity=49.2753623188406, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI4885081, Length=69, Percent_Identity=49.2753623188406, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI85794840, Length=73, Percent_Identity=49.3150684931507, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71996409, Length=73, Percent_Identity=49.3150684931507, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6226533, Length=69, Percent_Identity=47.8260869565217, Blast_Score=70, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24651601, Length=73, Percent_Identity=47.945205479452, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24651603, Length=73, Percent_Identity=47.945205479452, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24651599, Length=73, Percent_Identity=47.945205479452, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPL_GLUDA (A9HDM8)

Other databases:

- EMBL:   CP001189
- EMBL:   AM889285
- RefSeq:   YP_001601435.1
- RefSeq:   YP_002276267.1
- ProteinModelPortal:   A9HDM8
- GeneID:   5791619
- GeneID:   6975315
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_1892
- HOGENOM:   HBG753983
- OMA:   GIACLGM
- ProtClustDB:   CLSK936273
- HAMAP:   MF_01396
- InterPro:   IPR000454
- InterPro:   IPR020537
- InterPro:   IPR002379
- Gene3D:   G3DSA:1.20.20.10
- PRINTS:   PR00124

Pfam domain/function: PF00137 ATP-synt_C; SSF81333 ATPase_F0/V0_c

EC number: 3.6.3.14

Molecular weight: Translated: 7482; Mature: 7482

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS00605 ATPASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x132a7250)-; HASH(0x14879ec4)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIAAAREIGAGIAVIALAGVGIGLGNIFSTLVSSIARNPAARPHVFGLGMLGFALTEAV
CCCCHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ALYALLIAFLILFV
HHHHHHHHHHHHHH
>Mature Secondary Structure
MDIAAAREIGAGIAVIALAGVGIGLGNIFSTLVSSIARNPAARPHVFGLGMLGFALTEAV
CCCCHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ALYALLIAFLILFV
HHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA