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The map label for this gene is sglT [H]

Identifier: 162146951

GI number: 162146951

Start: 1151387

End: 1152895

Strand: Direct

Name: sglT [H]

Synonym: GDI_1156

Alternate gene names: 162146951

Gene position: 1151387-1152895 (Clockwise)

Preceding gene: 162146950

Following gene: 162146952

Centisome position: 29.19

GC content: 73.09

Gene sequence:

>1509_bases
ATGCCCCACGCCGAACCCGTCATCATCGGCCTGTACCTGCTGGTCCTGGCCGCCGTGTCGCTGGGCCTGTCGCGCGGCCG
CCATGTCGCGGCCGACTATCTGGCCGGCCGCCACGACATGCCGACCTGGGCGATCTGCCTGTCGATCGTCGCGACCGAGA
CATCGACCCTGACCATCGTCAGCGTCCCCGGCGTGGCCTATGGCGGCGGGATGGTCTTCGTCGGGCTGGGGCTGGGCTAT
CTGGTCGGGCGGATCGCGGTGGCGCGCATCCTGCTGCCGCTCTACATGCGGGGCGGCCCCGGGGGCAGCCTGGCCAGCGC
GTATCAATATCTGGGCCACCGGTTCGGACGGGACATGCAGCGCCTGGCGGCCGGCGCGTTCCTCCTGACCCGGCTGCTGG
CCGAGGGCGTGCGGCTGTTCGCCTCCACCCTGCCGATCTGCGCGCTGCTGGCGGCGGCGCACCTGCCGGCGGGGCGCATG
CCGGTGCTGATCGGGCTGACGGCGCTGACCGCGCTCTATACCGCCATCGGCGGGTTGCGGGCCGTCGTGTGGTCCGACAG
CATCCAGTTCGGCGTGTATGCCGCAGGGGCCGCGTTCTGCGTCGCCCTGCTGCTGCCCCGGGATGCCGCCGGATCGCTCG
ACATGACATCGCTGCACGCGGCCTGGCTGGCGGGGCGGTTCGCGCTGTTCCAGCGGGGGGGCGCGATCCTGACCTCGCCC
TACGCCCCGGTCACGGCGATCGTCGGCGGGGCCATCATGTCCATGGCGTCGCACGGCACGGACCAGTTGATGGTCCAGCG
GGTGCTGGCGGCCCGGTCGCTGCGCGCGGCCCAGGCCGCGATGATCGGCAGCGCCATCGTCGTCACGCTGCTGTTCGGCC
TGCTGTCGGCGGTGGGGGTGCTGCTATGGCTCCGCCATGGCGGGGCATCGCCGGCGGCGCTGGGCCTGCCCTCGCCCGAC
GCGCTGTTTCCCGCCTTCATCGCCCGCGACCTACCGCCGGCCCTGGCGGGGCTGCTGATCGCGGGGATCGTCAGCGCGAC
GATGGGATCGCTGGCCTCGGCGCTGAACGCCATGACGGCATCGACCCTGTCGGACCTGCTGCCCACCCGCCTGACGCGGC
GATCCGGCGCGGTGGCGCTGTCGCGGGCCATTACCGCCGCGTGGGCGGTGATGCTGGTCGTCACGGCGTCGTGCTTCTCG
GCCACCGGCCAGTCGGTGGTGATCTTCGGCCTGTCGATCGCGGGCTATTCCTACGGGGCGCTGCTGGGCGCGTTCCTGCT
GGGCCTGCTGGTCCGCGGCGCGCGGCAGCGCGATGCGGTCGCGGCCTTCCTGGGCACGCTGGCGATCATGACGGCGCTGA
TCCTGGGCGTGCATCCCGGGGGACACGCCATCGCCTTTCCCTGGCTGGTCCCGATCGGCGTGGCGGCCAGCCTGGCGATC
GGCGGCGCCTGCCGCCTGCGCCCGGACCCCATCCCCACCGACCAGCCGACGGAGCGGCCGACACCATGA

Upstream 100 bases:

>100_bases
TATCCTCGCAAACCCCGGCGAAGGGCCAAAGTTCCCGACCCGCCCCCCTCGGCCCCTTCCCCTGCCCTGCCCCCCGCCAC
GGGAGTACCACCGCGCCGCC

Downstream 100 bases:

>100_bases
CAGACGCCATGACGGATCTTGGCCGCCGGACGATCCTGCGGGCGATGGTCGCGGCCGGAGGCGCGGGACTGGCCGCCGGA
TGCGCCGCCGCCCCCGCCCG

Product: sodium cotransporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MPHAEPVIIGLYLLVLAAVSLGLSRGRHVAADYLAGRHDMPTWAICLSIVATETSTLTIVSVPGVAYGGGMVFVGLGLGY
LVGRIAVARILLPLYMRGGPGGSLASAYQYLGHRFGRDMQRLAAGAFLLTRLLAEGVRLFASTLPICALLAAAHLPAGRM
PVLIGLTALTALYTAIGGLRAVVWSDSIQFGVYAAGAAFCVALLLPRDAAGSLDMTSLHAAWLAGRFALFQRGGAILTSP
YAPVTAIVGGAIMSMASHGTDQLMVQRVLAARSLRAAQAAMIGSAIVVTLLFGLLSAVGVLLWLRHGGASPAALGLPSPD
ALFPAFIARDLPPALAGLLIAGIVSATMGSLASALNAMTASTLSDLLPTRLTRRSGAVALSRAITAAWAVMLVVTASCFS
ATGQSVVIFGLSIAGYSYGALLGAFLLGLLVRGARQRDAVAAFLGTLAIMTALILGVHPGGHAIAFPWLVPIGVAASLAI
GGACRLRPDPIPTDQPTERPTP

Sequences:

>Translated_502_residues
MPHAEPVIIGLYLLVLAAVSLGLSRGRHVAADYLAGRHDMPTWAICLSIVATETSTLTIVSVPGVAYGGGMVFVGLGLGY
LVGRIAVARILLPLYMRGGPGGSLASAYQYLGHRFGRDMQRLAAGAFLLTRLLAEGVRLFASTLPICALLAAAHLPAGRM
PVLIGLTALTALYTAIGGLRAVVWSDSIQFGVYAAGAAFCVALLLPRDAAGSLDMTSLHAAWLAGRFALFQRGGAILTSP
YAPVTAIVGGAIMSMASHGTDQLMVQRVLAARSLRAAQAAMIGSAIVVTLLFGLLSAVGVLLWLRHGGASPAALGLPSPD
ALFPAFIARDLPPALAGLLIAGIVSATMGSLASALNAMTASTLSDLLPTRLTRRSGAVALSRAITAAWAVMLVVTASCFS
ATGQSVVIFGLSIAGYSYGALLGAFLLGLLVRGARQRDAVAAFLGTLAIMTALILGVHPGGHAIAFPWLVPIGVAASLAI
GGACRLRPDPIPTDQPTERPTP
>Mature_501_residues
PHAEPVIIGLYLLVLAAVSLGLSRGRHVAADYLAGRHDMPTWAICLSIVATETSTLTIVSVPGVAYGGGMVFVGLGLGYL
VGRIAVARILLPLYMRGGPGGSLASAYQYLGHRFGRDMQRLAAGAFLLTRLLAEGVRLFASTLPICALLAAAHLPAGRMP
VLIGLTALTALYTAIGGLRAVVWSDSIQFGVYAAGAAFCVALLLPRDAAGSLDMTSLHAAWLAGRFALFQRGGAILTSPY
APVTAIVGGAIMSMASHGTDQLMVQRVLAARSLRAAQAAMIGSAIVVTLLFGLLSAVGVLLWLRHGGASPAALGLPSPDA
LFPAFIARDLPPALAGLLIAGIVSATMGSLASALNAMTASTLSDLLPTRLTRRSGAVALSRAITAAWAVMLVVTASCFSA
TGQSVVIFGLSIAGYSYGALLGAFLLGLLVRGARQRDAVAAFLGTLAIMTALILGVHPGGHAIAFPWLVPIGVAASLAIG
GACRLRPDPIPTDQPTERPTP

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI4507035, Length=437, Percent_Identity=27.9176201372998, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI167466278, Length=430, Percent_Identity=25.8139534883721, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI157671931, Length=451, Percent_Identity=24.8337028824834, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI256985183, Length=436, Percent_Identity=27.5229357798165, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI115533094, Length=372, Percent_Identity=27.9569892473118, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115533096, Length=247, Percent_Identity=29.9595141700405, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32566512, Length=393, Percent_Identity=22.3918575063613, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24651739, Length=446, Percent_Identity=26.2331838565022, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28573698, Length=450, Percent_Identity=25.3333333333333, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI221459584, Length=428, Percent_Identity=26.6355140186916, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24651741, Length=442, Percent_Identity=22.6244343891403, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281362918, Length=449, Percent_Identity=25.1670378619154, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28574994, Length=449, Percent_Identity=25.1670378619154, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24645928, Length=394, Percent_Identity=25.8883248730964, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641117, Length=433, Percent_Identity=27.2517321016166, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24650192, Length=435, Percent_Identity=26.6666666666667, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221459588, Length=469, Percent_Identity=25.1599147121535, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281364280, Length=374, Percent_Identity=25.4010695187166, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640370, Length=344, Percent_Identity=26.7441860465116, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI221459586, Length=453, Percent_Identity=26.4900662251656, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI221459582, Length=449, Percent_Identity=25.6124721603563, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920916, Length=357, Percent_Identity=25.7703081232493, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI161076631, Length=423, Percent_Identity=24.3498817966903, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221379702, Length=357, Percent_Identity=25.4901960784314, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281362054, Length=349, Percent_Identity=20.0573065902579, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281362052, Length=349, Percent_Identity=20.0573065902579, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281362050, Length=349, Percent_Identity=20.0573065902579, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648056, Length=349, Percent_Identity=20.0573065902579, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356827, Length=349, Percent_Identity=20.0573065902579, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 51360; Mature: 51228

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHAEPVIIGLYLLVLAAVSLGLSRGRHVAADYLAGRHDMPTWAICLSIVATETSTLTIV
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEE
SVPGVAYGGGMVFVGLGLGYLVGRIAVARILLPLYMRGGPGGSLASAYQYLGHRFGRDMQ
ECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
RLAAGAFLLTRLLAEGVRLFASTLPICALLAAAHLPAGRMPVLIGLTALTALYTAIGGLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AVVWSDSIQFGVYAAGAAFCVALLLPRDAAGSLDMTSLHAAWLAGRFALFQRGGAILTSP
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECC
YAPVTAIVGGAIMSMASHGTDQLMVQRVLAARSLRAAQAAMIGSAIVVTLLFGLLSAVGV
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLWLRHGGASPAALGLPSPDALFPAFIARDLPPALAGLLIAGIVSATMGSLASALNAMTA
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STLSDLLPTRLTRRSGAVALSRAITAAWAVMLVVTASCFSATGQSVVIFGLSIAGYSYGA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCHHHHH
LLGAFLLGLLVRGARQRDAVAAFLGTLAIMTALILGVHPGGHAIAFPWLVPIGVAASLAI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHH
GGACRLRPDPIPTDQPTERPTP
CCEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PHAEPVIIGLYLLVLAAVSLGLSRGRHVAADYLAGRHDMPTWAICLSIVATETSTLTIV
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEE
SVPGVAYGGGMVFVGLGLGYLVGRIAVARILLPLYMRGGPGGSLASAYQYLGHRFGRDMQ
ECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
RLAAGAFLLTRLLAEGVRLFASTLPICALLAAAHLPAGRMPVLIGLTALTALYTAIGGLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AVVWSDSIQFGVYAAGAAFCVALLLPRDAAGSLDMTSLHAAWLAGRFALFQRGGAILTSP
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECC
YAPVTAIVGGAIMSMASHGTDQLMVQRVLAARSLRAAQAAMIGSAIVVTLLFGLLSAVGV
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLWLRHGGASPAALGLPSPDALFPAFIARDLPPALAGLLIAGIVSATMGSLASALNAMTA
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STLSDLLPTRLTRRSGAVALSRAITAAWAVMLVVTASCFSATGQSVVIFGLSIAGYSYGA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCHHHHH
LLGAFLLGLLVRGARQRDAVAAFLGTLAIMTALILGVHPGGHAIAFPWLVPIGVAASLAI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHH
GGACRLRPDPIPTDQPTERPTP
CCEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]