Click here to switch to the map view.

The map label for this gene is ribD [H]

Identifier: 162146949

GI number: 162146949

Start: 1149483

End: 1150583

Strand: Reverse

Name: ribD [H]

Synonym: GDI_1154

Alternate gene names: 162146949

Gene position: 1150583-1149483 (Counterclockwise)

Preceding gene: 162146954

Following gene: 162146948

Centisome position: 29.17

GC content: 75.48

Gene sequence:

>1101_bases
GTGTCCGCTGCCGCCCTCGCCCCCCCTGTCGATCCGGCCCGCATCGCGCGGGCCTTCCGTGCCGCGCTGGCCGAGGCCGC
GCGGTATATGGGTGCCACCGCCCCCAAACCCCCCGTCGGCTGCGCCATCCTGGACGCGCGTGGCGAGATCCTGACCGTCG
CCGGCCATCACCGGGCCGGCGCCCCGCATGCCGAGGCCCTGGCCCTGCGCCAGTGCGCGGAACAGGGGCTGATGGATCGC
GCGTCGGTGGCCGTCGTGACCCTCGAACCCTGCAACCATACCGGCCGCACCGGCCCGTGTTCCGAGGCGATCCTGGCCTC
GCCCATTCGCACGGTCTGGGTGGGCGCCGCCGATCCCAATCCCCGCGTGGCCGGGGGCGGGGCCGCCCGGCTGCGCGCGG
CGGGCTGCGCCGTGTATGTGCTGGGGGAAGCGGGGGGCGAGCTGCTCCCCGATCCGTTCCCCGAACTGGCCGCTGCGTGC
CGGGCGCTGATCGCCCCCTTCGTGCACTGGTCGCGGACCGGTCGCGCGTGGCTGACGGTCAAGCAGGCGGTCGATGCGGA
CGGATCGATGATCCCGCCGGCCGGGCGGACGACCTTTACCTCCGACGCCGCGCTGACGCTGGCGCACCGGTTGCGCCGGG
CGACCGATGCCGTCGTGACCGGCAGCGGCACCGTGCTGGCCGACCGGCCGGGCCTGGATGTGCGGCGCGTGGCCGACCAT
GCGGACCGGGCCGCGCGGCCGCTGGTCGTCTGCGACCGGCGGGGGCGGGTGCCGGAGGACTGGCGCGCCGCCGCCAGGGG
GCGCGGGTTCGACGTGCGGACCTGCGACGATATCACCCGGCTGCCCGCGATGCTGGGGGCCGACGGCGTGCTGTGGGCGC
TGGTCGAGGCCGGGCCGGCCCTGCTGGATGCGCTGCGCGCGGCGGGGCTGTGGGATGACTGGCTGACCATCGGGGTCGGC
CCGGACGGGACGGAACGGATGGATGTCGCCGTCCGCTGCGGCACGGATACGCCGCTGCGCCTGTTCGCGGAACTGGCGGC
GCCGGGGACGGCACATCCAGGGACGGCACATGGGGAGGAAGCATGTTTTCCGGCATCATAG

Upstream 100 bases:

>100_bases
CGCCCTGGGTCCGTCCGGATGGATGGGACCGTTCGTGTTGGCTGCGCACTTGCGAGATTCGGGGACCGTGGAGGCCGCGC
ATGACGCGGCCGGCCGTTCC

Downstream 100 bases:

>100_bases
AGCATCTGGGCACCGTCACGGCGGCGCGGCGCGGCGACCGGTCGCTGCATGTCGCGGTGGCCACGGGCATCGGCGACCTG
TCGATGGGCGAGAGCATCGC

Product: riboflavin biosynthesis protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSAAALAPPVDPARIARAFRAALAEAARYMGATAPKPPVGCAILDARGEILTVAGHHRAGAPHAEALALRQCAEQGLMDR
ASVAVVTLEPCNHTGRTGPCSEAILASPIRTVWVGAADPNPRVAGGGAARLRAAGCAVYVLGEAGGELLPDPFPELAAAC
RALIAPFVHWSRTGRAWLTVKQAVDADGSMIPPAGRTTFTSDAALTLAHRLRRATDAVVTGSGTVLADRPGLDVRRVADH
ADRAARPLVVCDRRGRVPEDWRAAARGRGFDVRTCDDITRLPAMLGADGVLWALVEAGPALLDALRAAGLWDDWLTIGVG
PDGTERMDVAVRCGTDTPLRLFAELAAPGTAHPGTAHGEEACFPAS

Sequences:

>Translated_366_residues
MSAAALAPPVDPARIARAFRAALAEAARYMGATAPKPPVGCAILDARGEILTVAGHHRAGAPHAEALALRQCAEQGLMDR
ASVAVVTLEPCNHTGRTGPCSEAILASPIRTVWVGAADPNPRVAGGGAARLRAAGCAVYVLGEAGGELLPDPFPELAAAC
RALIAPFVHWSRTGRAWLTVKQAVDADGSMIPPAGRTTFTSDAALTLAHRLRRATDAVVTGSGTVLADRPGLDVRRVADH
ADRAARPLVVCDRRGRVPEDWRAAARGRGFDVRTCDDITRLPAMLGADGVLWALVEAGPALLDALRAAGLWDDWLTIGVG
PDGTERMDVAVRCGTDTPLRLFAELAAPGTAHPGTAHGEEACFPAS
>Mature_365_residues
SAAALAPPVDPARIARAFRAALAEAARYMGATAPKPPVGCAILDARGEILTVAGHHRAGAPHAEALALRQCAEQGLMDRA
SVAVVTLEPCNHTGRTGPCSEAILASPIRTVWVGAADPNPRVAGGGAARLRAAGCAVYVLGEAGGELLPDPFPELAAACR
ALIAPFVHWSRTGRAWLTVKQAVDADGSMIPPAGRTTFTSDAALTLAHRLRRATDAVVTGSGTVLADRPGLDVRRVADHA
DRAARPLVVCDRRGRVPEDWRAAARGRGFDVRTCDDITRLPAMLGADGVLWALVEAGPALLDALRAAGLWDDWLTIGVGP
DGTERMDVAVRCGTDTPLRLFAELAAPGTAHPGTAHGEEACFPAS

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=343, Percent_Identity=33.8192419825073, Blast_Score=127, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 37977; Mature: 37845

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAALAPPVDPARIARAFRAALAEAARYMGATAPKPPVGCAILDARGEILTVAGHHRAG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCC
APHAEALALRQCAEQGLMDRASVAVVTLEPCNHTGRTGPCSEAILASPIRTVWVGAADPN
CCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEEECCCCC
PRVAGGGAARLRAAGCAVYVLGEAGGELLPDPFPELAAACRALIAPFVHWSRTGRAWLTV
CCCCCCCHHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
KQAVDADGSMIPPAGRTTFTSDAALTLAHRLRRATDAVVTGSGTVLADRPGLDVRRVADH
EHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHEEEECCCEEEECCCCCHHHHHHHH
ADRAARPLVVCDRRGRVPEDWRAAARGRGFDVRTCDDITRLPAMLGADGVLWALVEAGPA
HHHHCCCEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCHH
LLDALRAAGLWDDWLTIGVGPDGTERMDVAVRCGTDTPLRLFAELAAPGTAHPGTAHGEE
HHHHHHHCCCCCCCEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCC
ACFPAS
CCCCCC
>Mature Secondary Structure 
SAAALAPPVDPARIARAFRAALAEAARYMGATAPKPPVGCAILDARGEILTVAGHHRAG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCC
APHAEALALRQCAEQGLMDRASVAVVTLEPCNHTGRTGPCSEAILASPIRTVWVGAADPN
CCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEEECCCCC
PRVAGGGAARLRAAGCAVYVLGEAGGELLPDPFPELAAACRALIAPFVHWSRTGRAWLTV
CCCCCCCHHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
KQAVDADGSMIPPAGRTTFTSDAALTLAHRLRRATDAVVTGSGTVLADRPGLDVRRVADH
EHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHEEEECCCEEEECCCCCHHHHHHHH
ADRAARPLVVCDRRGRVPEDWRAAARGRGFDVRTCDDITRLPAMLGADGVLWALVEAGPA
HHHHCCCEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCHH
LLDALRAAGLWDDWLTIGVGPDGTERMDVAVRCGTDTPLRLFAELAAPGTAHPGTAHGEE
HHHHHHHCCCCCCCEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCC
ACFPAS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]