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The map label for this gene is aatC [H]

Identifier: 162146851

GI number: 162146851

Start: 1049029

End: 1050252

Strand: Reverse

Name: aatC [H]

Synonym: GDI_1034

Alternate gene names: 162146851

Gene position: 1050252-1049029 (Counterclockwise)

Preceding gene: 162146852

Following gene: 162146850

Centisome position: 26.63

GC content: 68.63

Gene sequence:

>1224_bases
ATGACCGAAGAATTCCACCGCATCCGCCGCCTGCCGCCCTATGTGTTCGCCGAGGTCAACAAGGCCAAGGCCGCGGCGCG
AGCCCGGGGCGAGGACATCATCGATCTGGGCATGGGCAATCCCGACACCCCCACGCCGCCGCACATCGTGCAGAAGCTGG
TCGAGACGGTGGCTGATCCCCGGTCGCACCGCTATTCCGTCAGTCGCGGCATCCCCGGCCTGCGCCGGGCGCTGGCCGGC
TATTACGCCCGCCGCTTCGACGTGAAGCTGGACCCGGAAACAGAGGTGATCGCCACCCTGGGGTCCAAGGAAGGGCTGGC
CAACCTGTCGGCCGCGATCACCAGCCCGGGCGACACCATCCTGGTGCCCAACCCGTCCTATCCGATCCACCAGTTCGGCT
TCATCATCGCCGGCGCGTCCGTACGCTCGATCCCCGCCACGCCGGACGAGGAGATGCTGCGCGCGCTGGACCGCGCGGTG
CGCCATTCGGTGCCCAAGCCCACGGCGCTGATCGTCAATTTCCCGTCCAATCCCACGGCCTATGTCGCGGACCTGGATTT
CTATCGCGAACTGGTGGATTTCGCCCGCCGGCACGAGATCTGGATCATGTCCGACCTCGCCTATGCCGAGATCTATTTCG
GCGACAAGGTGCCGCCCTCGATCCTGCAGGTGCCGGGGGCGAAAGACATCGCCGTGGAATTCACCTCACTGTCCAAGACC
TATTCCATGGCGGGGTGGCGCATGGGCTTCGCGGCGGGCAATCCGCGCCTGATCACGGCGCTGACGCGCATCAAGTCCTA
TCTGGATTACGGGGCCTTCACCCCGATCCAGGTCGCGGCGGTCGCGGCCCTCAGCGGCCCGCAGGACTGCGTCGAGGAGA
TCCGCACCCTGTATCGCGACCGGCGCGACGTGCTGATCCGCGGCCTGCACGCGGCGGGCTGGGACGTACCCTCGCCCGAG
GGCTCGATGTTCGCCTGGGCCCCCGTCCCCGCCCCGTTCCGCGAGATGGGCAGCGTCGATTTCTCGAAGCTGCTGCTGAA
GGAAGCCGGGGTGGCGGTGGCGCCCGGCCTGGGCTTCGGCGAGTATGGCGAGGGCTTCGTGCGGATCGGCCTGGTGGAGA
ACACCCAGCGCCTGCGCCAGGCCACGCGGGCGATCCGCCAGTTCATGACCCGCCACGGCGTGGCCCCGGCCCGCGCCGAG
CCGGTGCCCGACGCGGCGCTTTGA

Upstream 100 bases:

>100_bases
CTGAACGGCGGGGAATTTACCCCGCCGGCCGCGACACGGCCGTCCTGAACCTGGTCCGCGGGCGGCACGCCCCCGGACGG
ATAGTCCCAACGAGCAACCC

Downstream 100 bases:

>100_bases
CCCACCCTTCCCGCCCGGGCACGGACCGGGCGGGGAAAAATCGCACCCCGCACAAGGGGGTTTGCCACGAACGACGACAG
GACATCAGGTGACCGGACGG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTEEFHRIRRLPPYVFAEVNKAKAAARARGEDIIDLGMGNPDTPTPPHIVQKLVETVADPRSHRYSVSRGIPGLRRALAG
YYARRFDVKLDPETEVIATLGSKEGLANLSAAITSPGDTILVPNPSYPIHQFGFIIAGASVRSIPATPDEEMLRALDRAV
RHSVPKPTALIVNFPSNPTAYVADLDFYRELVDFARRHEIWIMSDLAYAEIYFGDKVPPSILQVPGAKDIAVEFTSLSKT
YSMAGWRMGFAAGNPRLITALTRIKSYLDYGAFTPIQVAAVAALSGPQDCVEEIRTLYRDRRDVLIRGLHAAGWDVPSPE
GSMFAWAPVPAPFREMGSVDFSKLLLKEAGVAVAPGLGFGEYGEGFVRIGLVENTQRLRQATRAIRQFMTRHGVAPARAE
PVPDAAL

Sequences:

>Translated_407_residues
MTEEFHRIRRLPPYVFAEVNKAKAAARARGEDIIDLGMGNPDTPTPPHIVQKLVETVADPRSHRYSVSRGIPGLRRALAG
YYARRFDVKLDPETEVIATLGSKEGLANLSAAITSPGDTILVPNPSYPIHQFGFIIAGASVRSIPATPDEEMLRALDRAV
RHSVPKPTALIVNFPSNPTAYVADLDFYRELVDFARRHEIWIMSDLAYAEIYFGDKVPPSILQVPGAKDIAVEFTSLSKT
YSMAGWRMGFAAGNPRLITALTRIKSYLDYGAFTPIQVAAVAALSGPQDCVEEIRTLYRDRRDVLIRGLHAAGWDVPSPE
GSMFAWAPVPAPFREMGSVDFSKLLLKEAGVAVAPGLGFGEYGEGFVRIGLVENTQRLRQATRAIRQFMTRHGVAPARAE
PVPDAAL
>Mature_406_residues
TEEFHRIRRLPPYVFAEVNKAKAAARARGEDIIDLGMGNPDTPTPPHIVQKLVETVADPRSHRYSVSRGIPGLRRALAGY
YARRFDVKLDPETEVIATLGSKEGLANLSAAITSPGDTILVPNPSYPIHQFGFIIAGASVRSIPATPDEEMLRALDRAVR
HSVPKPTALIVNFPSNPTAYVADLDFYRELVDFARRHEIWIMSDLAYAEIYFGDKVPPSILQVPGAKDIAVEFTSLSKTY
SMAGWRMGFAAGNPRLITALTRIKSYLDYGAFTPIQVAAVAALSGPQDCVEEIRTLYRDRRDVLIRGLHAAGWDVPSPEG
SMFAWAPVPAPFREMGSVDFSKLLLKEAGVAVAPGLGFGEYGEGFVRIGLVENTQRLRQATRAIRQFMTRHGVAPARAEP
VPDAAL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=412, Percent_Identity=23.3009708737864, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI56713254, Length=412, Percent_Identity=23.3009708737864, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=22.0253164556962, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=22.0253164556962, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI4507369, Length=387, Percent_Identity=23.7726098191214, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1788722, Length=402, Percent_Identity=54.726368159204, Blast_Score=467, Evalue=1e-133,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=25.5434782608696, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788627, Length=318, Percent_Identity=27.0440251572327, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787710, Length=316, Percent_Identity=26.2658227848101, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=395, Percent_Identity=23.5443037974684, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=354, Percent_Identity=25.4237288135593, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71994472, Length=354, Percent_Identity=25.4237288135593, Blast_Score=98, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=21.8508997429306, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6320317, Length=343, Percent_Identity=22.4489795918367, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573069, Length=386, Percent_Identity=23.8341968911917, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24646114, Length=386, Percent_Identity=23.8341968911917, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28573067, Length=386, Percent_Identity=23.8341968911917, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28573065, Length=386, Percent_Identity=23.8341968911917, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI18859735, Length=390, Percent_Identity=25.6410256410256, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45551451, Length=395, Percent_Identity=24.3037974683544, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641770, Length=395, Percent_Identity=24.3037974683544, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641760, Length=395, Percent_Identity=24.3037974683544, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641768, Length=395, Percent_Identity=24.3037974683544, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641766, Length=395, Percent_Identity=24.3037974683544, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641764, Length=395, Percent_Identity=24.3037974683544, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44622; Mature: 44490

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEFHRIRRLPPYVFAEVNKAKAAARARGEDIIDLGMGNPDTPTPPHIVQKLVETVADP
CCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCC
RSHRYSVSRGIPGLRRALAGYYARRFDVKLDPETEVIATLGSKEGLANLSAAITSPGDTI
HHHCEEHHCCCHHHHHHHHHHHHHHCCEEECCCHHHHHHCCCCCCHHHHHHHCCCCCCEE
LVPNPSYPIHQFGFIIAGASVRSIPATPDEEMLRALDRAVRHSVPKPTALIVNFPSNPTA
EECCCCCCHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCE
YVADLDFYRELVDFARRHEIWIMSDLAYAEIYFGDKVPPSILQVPGAKDIAVEFTSLSKT
EEECHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCHHHHCCCCCCCEEEEHHHHHHH
YSMAGWRMGFAAGNPRLITALTRIKSYLDYGAFTPIQVAAVAALSGPQDCVEEIRTLYRD
HHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
RRDVLIRGLHAAGWDVPSPEGSMFAWAPVPAPFREMGSVDFSKLLLKEAGVAVAPGLGFG
HHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHCCCCHHHHHHHHCCCEEECCCCCC
EYGEGFVRIGLVENTQRLRQATRAIRQFMTRHGVAPARAEPVPDAAL
CCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEEFHRIRRLPPYVFAEVNKAKAAARARGEDIIDLGMGNPDTPTPPHIVQKLVETVADP
CHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCC
RSHRYSVSRGIPGLRRALAGYYARRFDVKLDPETEVIATLGSKEGLANLSAAITSPGDTI
HHHCEEHHCCCHHHHHHHHHHHHHHCCEEECCCHHHHHHCCCCCCHHHHHHHCCCCCCEE
LVPNPSYPIHQFGFIIAGASVRSIPATPDEEMLRALDRAVRHSVPKPTALIVNFPSNPTA
EECCCCCCHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCE
YVADLDFYRELVDFARRHEIWIMSDLAYAEIYFGDKVPPSILQVPGAKDIAVEFTSLSKT
EEECHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCHHHHCCCCCCCEEEEHHHHHHH
YSMAGWRMGFAAGNPRLITALTRIKSYLDYGAFTPIQVAAVAALSGPQDCVEEIRTLYRD
HHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
RRDVLIRGLHAAGWDVPSPEGSMFAWAPVPAPFREMGSVDFSKLLLKEAGVAVAPGLGFG
HHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHCCCCHHHHHHHHCCCEEECCCCCC
EYGEGFVRIGLVENTQRLRQATRAIRQFMTRHGVAPARAEPVPDAAL
CCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]