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The map label for this gene is ycgM [C]

Identifier: 162146813

GI number: 162146813

Start: 1010577

End: 1011413

Strand: Reverse

Name: ycgM [C]

Synonym: GDI_0995

Alternate gene names: 162146813

Gene position: 1011413-1010577 (Counterclockwise)

Preceding gene: 162146814

Following gene: 162146812

Centisome position: 25.64

GC content: 64.87

Gene sequence:

>837_bases
ATGAAGCTGTGCCGTTATGGGGAACCGGGAGAGGAACGTCCGGCTCTGATCGATCAGACGGGAGGCCTGCGCAGCTTGGC
GGGGGTGGTCGGGGACGTGTCGCCGGAGGTACTGGCGCCGGCGCGTCTGGCCGCCCTTGCGGCGATCGATCCGTCGAGCT
TGCCGCAGGTGGATCCTGGCCAGCGTCTGGGCGTGCCGGTCGCAGGGATCGGGAAATATATCTGCATTGGGCTGAATTAC
CGGGACCATGCGGAAGAGGCAGGGCTGCCGGTGCCCGACGAGCCGATCATCTTTCTCAAGGCGATCACGGCACTCTCCGG
GCCTGACGATCCGATCATCCCGCCGATTGGCGCGACACAGTTGGACTGGGAAGCTGAACTCGCCGTCATCATCGGCACGC
GCGCGAAGAATATCGCAGTCAGCGAGGCGCTGGATCATGTCGCGGGCTATTGCGTCGCCAACGACGTGTCCGAACGCGCC
TTCCAGATGCAGTCAAGCCAGTGGGACAAGGGCAAGGGATGCGATACGTTCGGGCCGCTCGGCCCGTGGCTGGTGAGCCG
GGACGAGGTGCCCGACCCTCAGAATCTCGCGATTTGGCTGGATGTGAATGGGCGCCGGATGCAATGCGGGACTACGCGCA
CGATGGTGTTTTCCGTCGCCGAGATCGTCGCCTATGTCAGCCGCTACATGACACTCATGCCCGGCGACGTCATCGCCACC
GGCACACCACCGGGTGTCGGAATGGGGATGCGGCCAGAGCCGGTCTATCTGCGGTCCGGCGATGTCGTGGAACTCGGGAT
CGAGGGGCTTGGCCGGCAGCGGCAATGCGTGGCCTGA

Upstream 100 bases:

>100_bases
TGCGGTGTCGCGATCACGGGATGCGAGACGGTCGTTGTGCATGCGCGCGAGCCATCCACTCTGGTTATCTGTGATTCCGA
CTGAGCGAAAGGAGACACGC

Downstream 100 bases:

>100_bases
TGCGCCTCGCGCCAGCAGCGGATCTGAATGAGGAGAGGGAGAAAGCATGATGAACGAGATTCTGGATACGATGTTTGCGC
GACGGGCGACGAAGCGTTTC

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKLCRYGEPGEERPALIDQTGGLRSLAGVVGDVSPEVLAPARLAALAAIDPSSLPQVDPGQRLGVPVAGIGKYICIGLNY
RDHAEEAGLPVPDEPIIFLKAITALSGPDDPIIPPIGATQLDWEAELAVIIGTRAKNIAVSEALDHVAGYCVANDVSERA
FQMQSSQWDKGKGCDTFGPLGPWLVSRDEVPDPQNLAIWLDVNGRRMQCGTTRTMVFSVAEIVAYVSRYMTLMPGDVIAT
GTPPGVGMGMRPEPVYLRSGDVVELGIEGLGRQRQCVA

Sequences:

>Translated_278_residues
MKLCRYGEPGEERPALIDQTGGLRSLAGVVGDVSPEVLAPARLAALAAIDPSSLPQVDPGQRLGVPVAGIGKYICIGLNY
RDHAEEAGLPVPDEPIIFLKAITALSGPDDPIIPPIGATQLDWEAELAVIIGTRAKNIAVSEALDHVAGYCVANDVSERA
FQMQSSQWDKGKGCDTFGPLGPWLVSRDEVPDPQNLAIWLDVNGRRMQCGTTRTMVFSVAEIVAYVSRYMTLMPGDVIAT
GTPPGVGMGMRPEPVYLRSGDVVELGIEGLGRQRQCVA
>Mature_278_residues
MKLCRYGEPGEERPALIDQTGGLRSLAGVVGDVSPEVLAPARLAALAAIDPSSLPQVDPGQRLGVPVAGIGKYICIGLNY
RDHAEEAGLPVPDEPIIFLKAITALSGPDDPIIPPIGATQLDWEAELAVIIGTRAKNIAVSEALDHVAGYCVANDVSERA
FQMQSSQWDKGKGCDTFGPLGPWLVSRDEVPDPQNLAIWLDVNGRRMQCGTTRTMVFSVAEIVAYVSRYMTLMPGDVIAT
GTPPGVGMGMRPEPVYLRSGDVVELGIEGLGRQRQCVA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=208, Percent_Identity=50, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI40786394, Length=208, Percent_Identity=48.5576923076923, Blast_Score=204, Evalue=7e-53,
Organism=Homo sapiens, GI66348062, Length=201, Percent_Identity=37.8109452736318, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI13654274, Length=201, Percent_Identity=37.8109452736318, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI215422413, Length=201, Percent_Identity=37.8109452736318, Blast_Score=136, Evalue=2e-32,
Organism=Escherichia coli, GI1787428, Length=204, Percent_Identity=35.7843137254902, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17557057, Length=200, Percent_Identity=35, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324161, Length=242, Percent_Identity=29.3388429752066, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28572127, Length=271, Percent_Identity=39.8523985239852, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24663695, Length=214, Percent_Identity=36.9158878504673, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571789, Length=205, Percent_Identity=36.5853658536585, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 29571; Mature: 29571

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLCRYGEPGEERPALIDQTGGLRSLAGVVGDVSPEVLAPARLAALAAIDPSSLPQVDPG
CCCCCCCCCCCCCCCEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
QRLGVPVAGIGKYICIGLNYRDHAEEAGLPVPDEPIIFLKAITALSGPDDPIIPPIGATQ
CCCCCCHHCCCCEEEEECCCHHHHHHCCCCCCCCCEEHEEHHHHHCCCCCCCCCCCCCCC
LDWEAELAVIIGTRAKNIAVSEALDHVAGYCVANDVSERAFQMQSSQWDKGKGCDTFGPL
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GPWLVSRDEVPDPQNLAIWLDVNGRRMQCGTTRTMVFSVAEIVAYVSRYMTLMPGDVIAT
CCHHCCCCCCCCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GTPPGVGMGMRPEPVYLRSGDVVELGIEGLGRQRQCVA
CCCCCCCCCCCCCCEEEECCCEEEECHHCCCCCCCCCC
>Mature Secondary Structure
MKLCRYGEPGEERPALIDQTGGLRSLAGVVGDVSPEVLAPARLAALAAIDPSSLPQVDPG
CCCCCCCCCCCCCCCEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
QRLGVPVAGIGKYICIGLNYRDHAEEAGLPVPDEPIIFLKAITALSGPDDPIIPPIGATQ
CCCCCCHHCCCCEEEEECCCHHHHHHCCCCCCCCCEEHEEHHHHHCCCCCCCCCCCCCCC
LDWEAELAVIIGTRAKNIAVSEALDHVAGYCVANDVSERAFQMQSSQWDKGKGCDTFGPL
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GPWLVSRDEVPDPQNLAIWLDVNGRRMQCGTTRTMVFSVAEIVAYVSRYMTLMPGDVIAT
CCHHCCCCCCCCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GTPPGVGMGMRPEPVYLRSGDVVELGIEGLGRQRQCVA
CCCCCCCCCCCCCCEEEECCCEEEECHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA