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The map label for this gene is ompR [H]

Identifier: 162146556

GI number: 162146556

Start: 751670

End: 752389

Strand: Reverse

Name: ompR [H]

Synonym: GDI_0733

Alternate gene names: 162146556

Gene position: 752389-751670 (Counterclockwise)

Preceding gene: 162146557

Following gene: 162146555

Centisome position: 19.08

GC content: 68.06

Gene sequence:

>720_bases
ATGGAGCCCTTGCCGCACATCCTGATTGTCGATGACGACCGTGAAATCCGCGACCTTCTCGCCCGTTTCCTGGAACGCAA
CCAGTTCCGCGTGACCACCGCGCGCGACGGGCGCGAAACCCGCAAGGCCTGGCTGGCCGGCCATTACCAGATCGTGGTGC
TGGACCTGATGCTGCCGGGCGAAAGCGGGCTGGAGCTGGCGCGCTGGCTGCGCGGGCAGGCCAACGTGCCGATCATCATG
CTGACGGCGATGGGCGAGGAAACCGACCGGATCATCGGGCTGGAACTGGGCGCCGACGATTACGTGCCCAAGCCGTTCAA
CCCGCGCGAATTGCTGGCGCGCATCCGCGCCGTGCTGCGCCGCAGCAGCGAGGCACCGGAAACCCGGGTGGTGGGCGAGC
CGCGCAGCCTGCATTTTTCGGGATGGACGCTGGAACAGGCACGGCGCCGGCTGCTGAACCCGGAAGGGACCGAGGTCCCG
CTGACGGGCGGGGAATACGACCTGCTGATGGCGCTGCTGGACCGGGCCAACCGCGTGCTGACCCGCGACATGCTGTTCGA
CCTGCTGCGCGGACGGCAGGCGGGGCCGTTCGACCGCGCGATCGACGTCGCCATCAGCCGGCTGCGCCGCAAGCTGGAAG
ATAACGGGCGCAACGCCCAGTTGATCAAGACGGTGCGCGGCGGCGGCTATGTCCTGGCGTCCGATGTCGAACGGCATTGA

Upstream 100 bases:

>100_bases
CCCCGATGGATGTTTTTTCACGCGACCGGGTCGCCCCGGCGGATTGCAACCGAATGAAACACCGGATGCCGGCCGCCTTG
TTTGGAGATAGAGTGATGAA

Downstream 100 bases:

>100_bases
TCCGGCGCGCGGTGCCGCGGACACGATTCTGAACGCCCCCGCCCCCGCGTCCTCGTCCTCTTCCGATGGCGACGCGGCGG
CCGGGCCGATCCGCCGGATG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MEPLPHILIVDDDREIRDLLARFLERNQFRVTTARDGRETRKAWLAGHYQIVVLDLMLPGESGLELARWLRGQANVPIIM
LTAMGEETDRIIGLELGADDYVPKPFNPRELLARIRAVLRRSSEAPETRVVGEPRSLHFSGWTLEQARRRLLNPEGTEVP
LTGGEYDLLMALLDRANRVLTRDMLFDLLRGRQAGPFDRAIDVAISRLRRKLEDNGRNAQLIKTVRGGGYVLASDVERH

Sequences:

>Translated_239_residues
MEPLPHILIVDDDREIRDLLARFLERNQFRVTTARDGRETRKAWLAGHYQIVVLDLMLPGESGLELARWLRGQANVPIIM
LTAMGEETDRIIGLELGADDYVPKPFNPRELLARIRAVLRRSSEAPETRVVGEPRSLHFSGWTLEQARRRLLNPEGTEVP
LTGGEYDLLMALLDRANRVLTRDMLFDLLRGRQAGPFDRAIDVAISRLRRKLEDNGRNAQLIKTVRGGGYVLASDVERH
>Mature_239_residues
MEPLPHILIVDDDREIRDLLARFLERNQFRVTTARDGRETRKAWLAGHYQIVVLDLMLPGESGLELARWLRGQANVPIIM
LTAMGEETDRIIGLELGADDYVPKPFNPRELLARIRAVLRRSSEAPETRVVGEPRSLHFSGWTLEQARRRLLNPEGTEVP
LTGGEYDLLMALLDRANRVLTRDMLFDLLRGRQAGPFDRAIDVAISRLRRKLEDNGRNAQLIKTVRGGGYVLASDVERH

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=46.9565217391304, Blast_Score=195, Evalue=2e-51,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=37.9746835443038, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=44.7826086956522, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=36.9098712446352, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=37.0689655172414, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=35.3448275862069, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=35.0210970464135, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=36.5638766519824, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=36.2068965517241, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=32.0175438596491, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=35.4978354978355, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=36.2445414847162, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=32.4561403508772, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=32.0175438596491, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788550, Length=130, Percent_Identity=30, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790299, Length=143, Percent_Identity=27.2727272727273, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27220; Mature: 27220

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPLPHILIVDDDREIRDLLARFLERNQFRVTTARDGRETRKAWLAGHYQIVVLDLMLPG
CCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCEEEEEEEEECCC
ESGLELARWLRGQANVPIIMLTAMGEETDRIIGLELGADDYVPKPFNPRELLARIRAVLR
CCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RSSEAPETRVVGEPRSLHFSGWTLEQARRRLLNPEGTEVPLTGGEYDLLMALLDRANRVL
CCCCCCCCEECCCCCEEEECCCCHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHH
TRDMLFDLLRGRQAGPFDRAIDVAISRLRRKLEDNGRNAQLIKTVRGGGYVLASDVERH
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCC
>Mature Secondary Structure
MEPLPHILIVDDDREIRDLLARFLERNQFRVTTARDGRETRKAWLAGHYQIVVLDLMLPG
CCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCEEEEEEEEECCC
ESGLELARWLRGQANVPIIMLTAMGEETDRIIGLELGADDYVPKPFNPRELLARIRAVLR
CCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RSSEAPETRVVGEPRSLHFSGWTLEQARRRLLNPEGTEVPLTGGEYDLLMALLDRANRVL
CCCCCCCCEECCCCCEEEECCCCHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHH
TRDMLFDLLRGRQAGPFDRAIDVAISRLRRKLEDNGRNAQLIKTVRGGGYVLASDVERH
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]