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The map label for this gene is 162146543

Identifier: 162146543

GI number: 162146543

Start: 734948

End: 736129

Strand: Reverse

Name: 162146543

Synonym: GDI_0719

Alternate gene names: NA

Gene position: 736129-734948 (Counterclockwise)

Preceding gene: 162146544

Following gene: 162146542

Centisome position: 18.66

GC content: 69.63

Gene sequence:

>1182_bases
ATGATGTTCGCCTTGCACGCCCTTGCCTCACCCGCCGGTCTTGCCGCCCTTGTCGCGGCGGCCGGATGCGTGCAGGCGAC
GCTGGGGACCGCACTGGTCGCGCGATTCCGCTGGCGCGAACGCCATATTCCCCCGGACAGCACGCTGCCGCCGGTCACGA
TCCTGAAGCCGCTGCATGGCGACGAGCCGCTGCTGGAGGAGGCGCTGGAGAGTTTCTGCACCCAGGATTATCCCGGCATG
CAGATCGTCTTCGGCGTGCAGGATGCCGGCGATCCGGCGATCGCGATCGTCAGGCGCCTGCGGGAACGCCATCCCGGCCT
GGACATCGCCCTGGTGGTCGATCCCGCCGTCCATGGCGTCAACCGCAAGATCGGCAACCTGATCAACATGCTGCCCCGGG
CCCGGCACGACGTGCTGGTCATCTCGGACTCCGACATCCACGTGGCGCCGGATTACCTGCGGCATGTCGTCCATGCGCTG
GCGCGGCCGGGCGTGGGCCTGGCCACCACGCTGTATGCCGGCCTGCCGGCGACGCGCAGCCTGCCGCGCCTGCTGGCGGC
ATGCCAGATCAACCACAATTTCCTGCCCGGGGTCATGCTGTCGCGCTATCTGGGGCGGCAGGACTGCCTGGGCGCCACCA
TGGCCCTGCGGCGCGAGACGCTGGATGCGGTGGGCGGCCTGGCGGCGCTGGCACCGCATATCGCCGACGACGCCATGCTG
GGCCGCCTGGTGCGCGAGCACGGGCTGCACATCGCCATCGCCCCCTGCATGACCTGGACCACGGTGGGCGAGCCGACCTT
CAACGACGTCATGCTTCACGAACTGCGCTGGGGCCGGACGGTCAAGACGCTGGAGCCGGCGGGCTATGCCGCGTCCGCCA
TCCAGCTTCCGCTGTTCTGGGCGGCGGCTGCCGTCCTGCTGCAACCGCATGCGCGCTGGACCTGGGCGGTCTTCCTGACC
GTCTGGGCGGTGCGGGCGGCCAGCGCCTTCCTGATGGACCGGCTGCTGGCGCAGCGCAGCCTGGTCCCGCTTCTGCTGCT
GCCGCTACGCGACTGGCTTTCCGCCGCGATCATGGTCGGCAGCGTCAGCGGCACGCGTGTCGCGTGGCGTGGACAGACGA
TGCATATCGCGCCACATTCGGTTATGACGCCTCCATCCCATCCTGTCGTGCCGGGCGACTGA

Upstream 100 bases:

>100_bases
GGAGCCCACCTGTACCTGTGATCCACCCGGTGGCCGTGCGCGCCCGATTCCTGGGCGCCCAATCGCTGGTCACCTTGTCT
GTGCCCCCGCTGCCGGAAAG

Downstream 100 bases:

>100_bases
CGCACCCCACACGACATAAGACAGACCAAGAATGGCGGCGCCGGACCGATGTCCCCCCGCCCGAGGATTTGCGTATCATG
ATGAGAACATTATTCCTGCA

Product: glycosyl transferase protein

Products: UDP; D-glucosyl-N-acylsphingosine

Alternate protein names: Glycosyltransferase; Glycosyl Transferase Family Protein; Glucosyltransferase; Cell Wall Biosynthesis Glycosyltransferase-Like Protein; Glycosyl Transferase Group 2 Family; Family 2 Glycosyl Transferase; Glycosyl Transferase; Cell Wall Biosynthesis Glycosyltransferase; Glycosyl Transferase Group 2 Family Protein; Acyl-CoA Dehydrogenase-Like; Acyl-CoA Dehydrogenase-Like Protein; UDP-GlucoseCeramide Glycosyltransferase; Glycosyltransferase Family; Glycosyl Transferase Protein; Glycosyl Tranferase Homolog; Syl Transferase Group 2 Family Protein; Putatiave Glycosyltransferase

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MMFALHALASPAGLAALVAAAGCVQATLGTALVARFRWRERHIPPDSTLPPVTILKPLHGDEPLLEEALESFCTQDYPGM
QIVFGVQDAGDPAIAIVRRLRERHPGLDIALVVDPAVHGVNRKIGNLINMLPRARHDVLVISDSDIHVAPDYLRHVVHAL
ARPGVGLATTLYAGLPATRSLPRLLAACQINHNFLPGVMLSRYLGRQDCLGATMALRRETLDAVGGLAALAPHIADDAML
GRLVREHGLHIAIAPCMTWTTVGEPTFNDVMLHELRWGRTVKTLEPAGYAASAIQLPLFWAAAAVLLQPHARWTWAVFLT
VWAVRAASAFLMDRLLAQRSLVPLLLLPLRDWLSAAIMVGSVSGTRVAWRGQTMHIAPHSVMTPPSHPVVPGD

Sequences:

>Translated_393_residues
MMFALHALASPAGLAALVAAAGCVQATLGTALVARFRWRERHIPPDSTLPPVTILKPLHGDEPLLEEALESFCTQDYPGM
QIVFGVQDAGDPAIAIVRRLRERHPGLDIALVVDPAVHGVNRKIGNLINMLPRARHDVLVISDSDIHVAPDYLRHVVHAL
ARPGVGLATTLYAGLPATRSLPRLLAACQINHNFLPGVMLSRYLGRQDCLGATMALRRETLDAVGGLAALAPHIADDAML
GRLVREHGLHIAIAPCMTWTTVGEPTFNDVMLHELRWGRTVKTLEPAGYAASAIQLPLFWAAAAVLLQPHARWTWAVFLT
VWAVRAASAFLMDRLLAQRSLVPLLLLPLRDWLSAAIMVGSVSGTRVAWRGQTMHIAPHSVMTPPSHPVVPGD
>Mature_393_residues
MMFALHALASPAGLAALVAAAGCVQATLGTALVARFRWRERHIPPDSTLPPVTILKPLHGDEPLLEEALESFCTQDYPGM
QIVFGVQDAGDPAIAIVRRLRERHPGLDIALVVDPAVHGVNRKIGNLINMLPRARHDVLVISDSDIHVAPDYLRHVVHAL
ARPGVGLATTLYAGLPATRSLPRLLAACQINHNFLPGVMLSRYLGRQDCLGATMALRRETLDAVGGLAALAPHIADDAML
GRLVREHGLHIAIAPCMTWTTVGEPTFNDVMLHELRWGRTVKTLEPAGYAASAIQLPLFWAAAAVLLQPHARWTWAVFLT
VWAVRAASAFLMDRLLAQRSLVPLLLLPLRDWLSAAIMVGSVSGTRVAWRGQTMHIAPHSVMTPPSHPVVPGD

Specific function: Unknown

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4507811, Length=287, Percent_Identity=29.9651567944251, Blast_Score=118, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI32566973, Length=259, Percent_Identity=24.7104247104247, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI25149577, Length=226, Percent_Identity=26.1061946902655, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32564728, Length=226, Percent_Identity=26.1061946902655, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25149574, Length=226, Percent_Identity=26.1061946902655, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25147526, Length=228, Percent_Identity=25.8771929824561, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25149580, Length=226, Percent_Identity=26.1061946902655, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24657569, Length=237, Percent_Identity=31.6455696202532, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.1.80

Molecular weight: Translated: 42549; Mature: 42549

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFALHALASPAGLAALVAAAGCVQATLGTALVARFRWRERHIPPDSTLPPVTILKPLHG
CEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEECCCCC
DEPLLEEALESFCTQDYPGMQIVFGVQDAGDPAIAIVRRLRERHPGLDIALVVDPAVHGV
CCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHH
NRKIGNLINMLPRARHDVLVISDSDIHVAPDYLRHVVHALARPGVGLATTLYAGLPATRS
HHHHHHHHHHHCCCCCCEEEEECCCCEECHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHH
LPRLLAACQINHNFLPGVMLSRYLGRQDCLGATMALRRETLDAVGGLAALAPHIADDAML
HHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRLVREHGLHIAIAPCMTWTTVGEPTFNDVMLHELRWGRTVKTLEPAGYAASAIQLPLFW
HHHHHHCCCEEEEECCEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHH
AAAAVLLQPHARWTWAVFLTVWAVRAASAFLMDRLLAQRSLVPLLLLPLRDWLSAAIMVG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SVSGTRVAWRGQTMHIAPHSVMTPPSHPVVPGD
CCCCCEEEECCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMFALHALASPAGLAALVAAAGCVQATLGTALVARFRWRERHIPPDSTLPPVTILKPLHG
CEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEECCCCC
DEPLLEEALESFCTQDYPGMQIVFGVQDAGDPAIAIVRRLRERHPGLDIALVVDPAVHGV
CCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHH
NRKIGNLINMLPRARHDVLVISDSDIHVAPDYLRHVVHALARPGVGLATTLYAGLPATRS
HHHHHHHHHHHCCCCCCEEEEECCCCEECHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHH
LPRLLAACQINHNFLPGVMLSRYLGRQDCLGATMALRRETLDAVGGLAALAPHIADDAML
HHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRLVREHGLHIAIAPCMTWTTVGEPTFNDVMLHELRWGRTVKTLEPAGYAASAIQLPLFW
HHHHHHCCCEEEEECCEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHH
AAAAVLLQPHARWTWAVFLTVWAVRAASAFLMDRLLAQRSLVPLLLLPLRDWLSAAIMVG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SVSGTRVAWRGQTMHIAPHSVMTPPSHPVVPGD
CCCCCEEEECCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-glucose; N-acylsphingosine

Specific reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA