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The map label for this gene is mntH [H]

Identifier: 162146478

GI number: 162146478

Start: 662581

End: 663882

Strand: Direct

Name: mntH [H]

Synonym: GDI_0654

Alternate gene names: 162146478

Gene position: 662581-663882 (Clockwise)

Preceding gene: 162146475

Following gene: 162146479

Centisome position: 16.8

GC content: 69.59

Gene sequence:

>1302_bases
ATGCCCGATCCATTCGCCAGCCTGGCCGAAGCCCATGCCTCGGTCCACGTTCCGCCCGGCGCCACCGGCTGGCGGCGGCT
GATGGCCTTCGCCGGGCCGGGATACATGGTATCGGTCGGCTATATGGACCCGGGCAACTGGGCCACGGACCTGGCGGGCG
GGTCGGCGTTCGGATACCGGCTGCTGTCGGTCATCATGCTGTCGAACCTGATGGCCATCCTGCTGCAGGCCCTGTCGGCC
CGGCTGGGGATCGCCACCGGGCGGGACCTGGCGCAGGCGTGCCGCGACCGGTTCCCGATGCCGGTCACCATCGCGCTCTG
GCTGGCGTGCGAGGCCGCGATCATCGCCTGCGACCTGGCGGAGGTCATCGGCACCGCGATCGCGCTGCAATTGCTGTTCG
GCCTCCCGCTGCTGCCGGGCGCCATCCTCACCGGCCTGGACGCCGCCCTGGTGCTGATGCTGATGAACCGCGGATTCCGC
GTGCTGGAGGCCTTCGTGATCGGCCTGCTGGTCATCATCGCCGCGTGCTTCCTGGTCCAGATCCTCGCGGCGGCCCCGCC
CGTGGCGGCGGTCCTGCGTGGCCTGGTTCCGACGCCCGCCCTGCTGACCGACCCGGCCATGCTGTATGTCGCCATCGGCA
TCATCGGGGCGACGGTCATGCCGCATAACCTGTACCTCCATTCCTCGATCGTGCAGACGCGGGCCTATGACCGGTCCGAG
GCCGGGCGCCGCGACGCGATCCGCTGGGCCACCTGGGACAGCACGCTGGCGCTGATGATGGCGCTTTTCATCAATGCCGC
GATCCTGATCGTCGCCAGTGCCGCCTTCCATGGCAGCGGGCATCGCGACGTGGCCGATATCGGGCAGGCCTATCGCCTGA
TCTCGCCGCTGCTGGGGCTGGGCGTGGCCTCGACGCTGTTCGCCGTGGCGCTGCTGGCGGCGGGGATGAATTCGACCGTC
ACCGGCACCCTGGCCGGCCAGATCGTGATGGAGGGATTCCTGCATGTGCGCCTGCCGCACTGGGCGCGGCGGCTGCTGAC
CCGGGGACTGGCCATCGTGCCGGTGGTGGTGGTCACGGCGCTGTACGGCGCGGCGGGCACGAACCGGCTGCTGGTGTTCA
GCCAGGTGGTGCTGTCGATGCAATTGCCCTTCGCCGTCATTCCGCTGGTCTGGTTCGTCGCCGATCGGCGGATGATGGGC
TCCTTCGCCATCTCGCGCGGGTTCGCGGCCCTGTCATGGCTGGTCGCCCTGGTCATCCTGGCGCTGAACGGCAAGCTGCT
GTGGGACATGGCGACGGGCTGA

Upstream 100 bases:

>100_bases
CATATACCAAATGGCCTGCGCCACATCATATAGCTTATTGCATATTCTCATCCTCCGCCCCTACGCTGGACGGGCTTCCT
CCCCCTTGGTGTGCCGCCCG

Downstream 100 bases:

>100_bases
TCCGATGCCGGATGCTTCCTTGTCCGCGACGCTCAGCGTGGCCGCGCTGGCGGCGGTGATCGAATGGCGCGTCGGCTATC
CCGCCCCGGTCTTCGCATGG

Product: manganese transport protein mntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MPDPFASLAEAHASVHVPPGATGWRRLMAFAGPGYMVSVGYMDPGNWATDLAGGSAFGYRLLSVIMLSNLMAILLQALSA
RLGIATGRDLAQACRDRFPMPVTIALWLACEAAIIACDLAEVIGTAIALQLLFGLPLLPGAILTGLDAALVLMLMNRGFR
VLEAFVIGLLVIIAACFLVQILAAAPPVAAVLRGLVPTPALLTDPAMLYVAIGIIGATVMPHNLYLHSSIVQTRAYDRSE
AGRRDAIRWATWDSTLALMMALFINAAILIVASAAFHGSGHRDVADIGQAYRLISPLLGLGVASTLFAVALLAAGMNSTV
TGTLAGQIVMEGFLHVRLPHWARRLLTRGLAIVPVVVVTALYGAAGTNRLLVFSQVVLSMQLPFAVIPLVWFVADRRMMG
SFAISRGFAALSWLVALVILALNGKLLWDMATG

Sequences:

>Translated_433_residues
MPDPFASLAEAHASVHVPPGATGWRRLMAFAGPGYMVSVGYMDPGNWATDLAGGSAFGYRLLSVIMLSNLMAILLQALSA
RLGIATGRDLAQACRDRFPMPVTIALWLACEAAIIACDLAEVIGTAIALQLLFGLPLLPGAILTGLDAALVLMLMNRGFR
VLEAFVIGLLVIIAACFLVQILAAAPPVAAVLRGLVPTPALLTDPAMLYVAIGIIGATVMPHNLYLHSSIVQTRAYDRSE
AGRRDAIRWATWDSTLALMMALFINAAILIVASAAFHGSGHRDVADIGQAYRLISPLLGLGVASTLFAVALLAAGMNSTV
TGTLAGQIVMEGFLHVRLPHWARRLLTRGLAIVPVVVVTALYGAAGTNRLLVFSQVVLSMQLPFAVIPLVWFVADRRMMG
SFAISRGFAALSWLVALVILALNGKLLWDMATG
>Mature_432_residues
PDPFASLAEAHASVHVPPGATGWRRLMAFAGPGYMVSVGYMDPGNWATDLAGGSAFGYRLLSVIMLSNLMAILLQALSAR
LGIATGRDLAQACRDRFPMPVTIALWLACEAAIIACDLAEVIGTAIALQLLFGLPLLPGAILTGLDAALVLMLMNRGFRV
LEAFVIGLLVIIAACFLVQILAAAPPVAAVLRGLVPTPALLTDPAMLYVAIGIIGATVMPHNLYLHSSIVQTRAYDRSEA
GRRDAIRWATWDSTLALMMALFINAAILIVASAAFHGSGHRDVADIGQAYRLISPLLGLGVASTLFAVALLAAGMNSTVT
GTLAGQIVMEGFLHVRLPHWARRLLTRGLAIVPVVVVTALYGAAGTNRLLVFSQVVLSMQLPFAVIPLVWFVADRRMMGS
FAISRGFAALSWLVALVILALNGKLLWDMATG

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=426, Percent_Identity=37.793427230047, Blast_Score=245, Evalue=5e-65,
Organism=Homo sapiens, GI295293167, Length=428, Percent_Identity=36.9158878504673, Blast_Score=235, Evalue=6e-62,
Organism=Homo sapiens, GI295293178, Length=428, Percent_Identity=36.9158878504673, Blast_Score=234, Evalue=8e-62,
Organism=Homo sapiens, GI295293171, Length=428, Percent_Identity=36.9158878504673, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI295293169, Length=428, Percent_Identity=36.9158878504673, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI295293175, Length=428, Percent_Identity=36.9158878504673, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI295293173, Length=428, Percent_Identity=36.9158878504673, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI10835169, Length=428, Percent_Identity=36.9158878504673, Blast_Score=234, Evalue=9e-62,
Organism=Escherichia coli, GI1788736, Length=419, Percent_Identity=42.4821002386635, Blast_Score=306, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI71999499, Length=451, Percent_Identity=33.4811529933481, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI193210616, Length=461, Percent_Identity=33.4056399132321, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17569473, Length=402, Percent_Identity=36.0696517412935, Blast_Score=237, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI71993856, Length=236, Percent_Identity=36.4406779661017, Blast_Score=154, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6323062, Length=400, Percent_Identity=43.75, Blast_Score=290, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6321841, Length=437, Percent_Identity=39.1304347826087, Blast_Score=262, Evalue=7e-71,
Organism=Saccharomyces cerevisiae, GI6324450, Length=420, Percent_Identity=37.3809523809524, Blast_Score=251, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24648607, Length=430, Percent_Identity=33.4883720930233, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI281362176, Length=430, Percent_Identity=33.4883720930233, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24648609, Length=430, Percent_Identity=33.4883720930233, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI45553443, Length=409, Percent_Identity=33.9853300733496, Blast_Score=234, Evalue=9e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 45782; Mature: 45651

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPFASLAEAHASVHVPPGATGWRRLMAFAGPGYMVSVGYMDPGNWATDLAGGSAFGYR
CCCHHHHHHHHHCEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCHHHHHH
LLSVIMLSNLMAILLQALSARLGIATGRDLAQACRDRFPMPVTIALWLACEAAIIACDLA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EVIGTAIALQLLFGLPLLPGAILTGLDAALVLMLMNRGFRVLEAFVIGLLVIIAACFLVQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ILAAAPPVAAVLRGLVPTPALLTDPAMLYVAIGIIGATVMPHNLYLHSSIVQTRAYDRSE
HHHCCCCHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHC
AGRRDAIRWATWDSTLALMMALFINAAILIVASAAFHGSGHRDVADIGQAYRLISPLLGL
CCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
GVASTLFAVALLAAGMNSTVTGTLAGQIVMEGFLHVRLPHWARRLLTRGLAIVPVVVVTA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHH
LYGAAGTNRLLVFSQVVLSMQLPFAVIPLVWFVADRRMMGSFAISRGFAALSWLVALVIL
HHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALNGKLLWDMATG
HHCCCEEEEECCC
>Mature Secondary Structure 
PDPFASLAEAHASVHVPPGATGWRRLMAFAGPGYMVSVGYMDPGNWATDLAGGSAFGYR
CCHHHHHHHHHCEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCHHHHHH
LLSVIMLSNLMAILLQALSARLGIATGRDLAQACRDRFPMPVTIALWLACEAAIIACDLA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EVIGTAIALQLLFGLPLLPGAILTGLDAALVLMLMNRGFRVLEAFVIGLLVIIAACFLVQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ILAAAPPVAAVLRGLVPTPALLTDPAMLYVAIGIIGATVMPHNLYLHSSIVQTRAYDRSE
HHHCCCCHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHC
AGRRDAIRWATWDSTLALMMALFINAAILIVASAAFHGSGHRDVADIGQAYRLISPLLGL
CCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
GVASTLFAVALLAAGMNSTVTGTLAGQIVMEGFLHVRLPHWARRLLTRGLAIVPVVVVTA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHH
LYGAAGTNRLLVFSQVVLSMQLPFAVIPLVWFVADRRMMGSFAISRGFAALSWLVALVIL
HHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALNGKLLWDMATG
HHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]