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The map label for this gene is nadA [H]

Identifier: 162146395

GI number: 162146395

Start: 578577

End: 579563

Strand: Direct

Name: nadA [H]

Synonym: GDI_0570

Alternate gene names: 162146395

Gene position: 578577-579563 (Clockwise)

Preceding gene: 162146394

Following gene: 162146396

Centisome position: 14.67

GC content: 66.16

Gene sequence:

>987_bases
ATGTCCGAGACTCTCGTCGCCCCGTCCAAGCTCGACGCGCTTTATGACCGCGTCGCCCGCGTCGTCCCGCGCATGGAATG
GGATCTGTTCGCCGACGACATCGCGGCCATCCTGGACCTGAAGCGCCGGCGCGGGGCGGTGATCCTGGCCCATAACTACC
AGACGCCGGAAATCTTCCATTGCATCGCCGACATTCGGGGCGACAGCCTGGCCCTGGCGCGTGACGCCCAGGGGCTGGAT
GCTGAGGTCATCGTCATGGCCGGCGTGCATTTCATGGCCGAAACCGCGAAGCTGATGAATCCGGAAAAGACGGTGCTGAT
CCCGTCGCTGCACGCCGGGTGCTCGCTGGCGGATTCGATCACGGCCGAGGACGTGCGCGCGCTGCGCCGCGCCCATCCGG
GCGTGCCGGTCGTCACCTACGTGAACAGCTCGGCCGAAGTGAAGGCCGAAAGCGATATCTGCTGCACCTCGGCCAATGCG
CGCCGCATCGTCGAAAGCCTGGGCGTGCCGCGCGTCATCATGATCCCCGACGAATTCCTGGCCCAGAACATCCAGCGGGA
AACCGGGGTCGAGATGATCACCTGGGCCGGCCATTGCGAGGTCCATGAACGCTTCACGCCGGAGGAAATCCGCACCTGGC
GCGCCGACAATCCCGATGTCGCGGTGCTGGCGCATCCGGAATGCCCGCCTTCGGTCGTCGCCGAGGCCGATTTTTCCGGC
TCCACGGCGGCGATGTCCGATTTCGTGGCGCGCGGCACGCACCGCAAGGTGATGCTGGTGACCGAATGTTCCATGAGCGA
CAACCTGGCGGCGTCCCATCCCACCGTCGAATTCGTGCGCCCGTGCAATCTTTGCCCGCACATGAAGCGCATCACCCTGC
CGGCGATCCGCCGGGCCCTGGAAACCATGACGCACGAGGTGACGATTCCCCCGCATCTGGTGGCGGGCGGGCGTCGCGCC
GTGGAACGGATGCTCGCCGCGTCATGA

Upstream 100 bases:

>100_bases
TTCGCTTGACGGCGCGCGCGCATTGGCGGAACAAGACCGGCGAGTTCATGTACCCAATTTATACTCACAGTGAGTATAAA
TTGGGCCGAAGGAGCCGAAC

Downstream 100 bases:

>100_bases
CCGGTCCGGGCCTCACCGACGCCGGTTCCTGGGCCGGCCAGCCGGTCATCGCCGGGGCGGGGCTGGCCGGGCTGGCGACG
GCGCTGCTGATGGACCGTCC

Product: quinolinate synthetase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSETLVAPSKLDALYDRVARVVPRMEWDLFADDIAAILDLKRRRGAVILAHNYQTPEIFHCIADIRGDSLALARDAQGLD
AEVIVMAGVHFMAETAKLMNPEKTVLIPSLHAGCSLADSITAEDVRALRRAHPGVPVVTYVNSSAEVKAESDICCTSANA
RRIVESLGVPRVIMIPDEFLAQNIQRETGVEMITWAGHCEVHERFTPEEIRTWRADNPDVAVLAHPECPPSVVAEADFSG
STAAMSDFVARGTHRKVMLVTECSMSDNLAASHPTVEFVRPCNLCPHMKRITLPAIRRALETMTHEVTIPPHLVAGGRRA
VERMLAAS

Sequences:

>Translated_328_residues
MSETLVAPSKLDALYDRVARVVPRMEWDLFADDIAAILDLKRRRGAVILAHNYQTPEIFHCIADIRGDSLALARDAQGLD
AEVIVMAGVHFMAETAKLMNPEKTVLIPSLHAGCSLADSITAEDVRALRRAHPGVPVVTYVNSSAEVKAESDICCTSANA
RRIVESLGVPRVIMIPDEFLAQNIQRETGVEMITWAGHCEVHERFTPEEIRTWRADNPDVAVLAHPECPPSVVAEADFSG
STAAMSDFVARGTHRKVMLVTECSMSDNLAASHPTVEFVRPCNLCPHMKRITLPAIRRALETMTHEVTIPPHLVAGGRRA
VERMLAAS
>Mature_327_residues
SETLVAPSKLDALYDRVARVVPRMEWDLFADDIAAILDLKRRRGAVILAHNYQTPEIFHCIADIRGDSLALARDAQGLDA
EVIVMAGVHFMAETAKLMNPEKTVLIPSLHAGCSLADSITAEDVRALRRAHPGVPVVTYVNSSAEVKAESDICCTSANAR
RIVESLGVPRVIMIPDEFLAQNIQRETGVEMITWAGHCEVHERFTPEEIRTWRADNPDVAVLAHPECPPSVVAEADFSGS
TAAMSDFVARGTHRKVMLVTECSMSDNLAASHPTVEFVRPCNLCPHMKRITLPAIRRALETMTHEVTIPPHLVAGGRRAV
ERMLAAS

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=308, Percent_Identity=35.0649350649351, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 35953; Mature: 35822

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETLVAPSKLDALYDRVARVVPRMEWDLFADDIAAILDLKRRRGAVILAHNYQTPEIFH
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHH
CIADIRGDSLALARDAQGLDAEVIVMAGVHFMAETAKLMNPEKTVLIPSLHAGCSLADSI
HHHHCCCCCEEEECCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHC
TAEDVRALRRAHPGVPVVTYVNSSAEVKAESDICCTSANARRIVESLGVPRVIMIPDEFL
CHHHHHHHHHHCCCCCEEEEECCCCCEEECCCEEECCCHHHHHHHHCCCCEEEECCHHHH
AQNIQRETGVEMITWAGHCEVHERFTPEEIRTWRADNPDVAVLAHPECPPSVVAEADFSG
HHHHHHHCCCEEEEECCCCCHHCCCCHHHHHHCCCCCCCEEEEECCCCCHHHEEECCCCC
STAAMSDFVARGTHRKVMLVTECSMSDNLAASHPTVEFVRPCNLCPHMKRITLPAIRRAL
CHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCHHHCCHHHHHHHH
ETMTHEVTIPPHLVAGGRRAVERMLAAS
HHHHCEECCCCHHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
SETLVAPSKLDALYDRVARVVPRMEWDLFADDIAAILDLKRRRGAVILAHNYQTPEIFH
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHH
CIADIRGDSLALARDAQGLDAEVIVMAGVHFMAETAKLMNPEKTVLIPSLHAGCSLADSI
HHHHCCCCCEEEECCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHC
TAEDVRALRRAHPGVPVVTYVNSSAEVKAESDICCTSANARRIVESLGVPRVIMIPDEFL
CHHHHHHHHHHCCCCCEEEEECCCCCEEECCCEEECCCHHHHHHHHCCCCEEEECCHHHH
AQNIQRETGVEMITWAGHCEVHERFTPEEIRTWRADNPDVAVLAHPECPPSVVAEADFSG
HHHHHHHCCCEEEEECCCCCHHCCCCHHHHHHCCCCCCCEEEEECCCCCHHHEEECCCCC
STAAMSDFVARGTHRKVMLVTECSMSDNLAASHPTVEFVRPCNLCPHMKRITLPAIRRAL
CHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCHHHCCHHHHHHHH
ETMTHEVTIPPHLVAGGRRAVERMLAAS
HHHHCEECCCCHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]