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The map label for this gene is ttgC [H]

Identifier: 162146389

GI number: 162146389

Start: 572436

End: 573848

Strand: Direct

Name: ttgC [H]

Synonym: GDI_0564

Alternate gene names: 162146389

Gene position: 572436-573848 (Clockwise)

Preceding gene: 162146388

Following gene: 162146392

Centisome position: 14.51

GC content: 69.5

Gene sequence:

>1413_bases
GTGATGTCATGCCACAGCCGCGCGTGGCGTGTCCTGATGCTGCTGGCGGCCATGGTACCGGCTGCCTGCGACCTGGCGCC
GCGCTATGCGCCGCCCGTGGCGCCGGTCCCGGCATCGTTCAAGGAACGGGACGGATGGGCCCTGGCGGTGCCGGGGGACG
ATGTGCCGAAGGGGCCATGGTGGCGGATCTTCCACGATCCTGTTCTCGATGCGCTGGAAGACCGGGTCACGATCGCGAAC
CAGGACCTGCGGGTCGCCGTCGCGCAATATGACGAAGCCCGCGCCGACGCCCGCACGGCCCAGGCCGGCTATTACCCCAC
GCTGGATTTCACCGGTTCCGCGTCGCGATCGGGCCTGTCGCGCGAAACCGCGAACGTGTTCAACAAGTCGACCTTCAACA
GCTACAGCCTGGGCCTGGACCTGCAATACGAGGTCGACGTCTGGGGCCGCGTCCGCAATACCGCGAAGGCCGGCCGGGCA
CGGGCGCAGGCCAGCGCCGGGGACCTCGCCACGGTCGATCTCAGCCTTCATGCCGAACTCGCGACCGATTACTTCACGCT
GCGCGGCTACGACGCCATGCAGGCGGTCCTGGACCAGACGGTCGGCAATTACCGGCATGCGCTGGCCCTGACCCAGGCGC
AGTTCGATGTCGGCTACGCGGCGCAGCCCGATGTATCCGCCGCCACCGCGCAGCTCGACGGGCTGCTGACCCAGGCCGCC
GACAACCGGTTGCGGCGGGCCATGCTGGAACATGCTATCGCCATCCTGACCGGCCAGCCGCCGGCGACATTCGCCGTCGC
GGCGCGTTCGCTCGATTCCGCCCCGCCCCCGATCGCCCCCGGCCTGCCGGTGGCGCTGCTGCAGCGCCGGCCGGACATCG
CGGCGGCGGAACGGCGCGTCGCGGCGGCCAACGCCGATATCGGCGTGGCGCGGGCGGCGTATTTTCCCGCTTTCAACATC
AACGCCATGATGGGCGTGCAGGCCGCCATGCCCAACCACCTTCTGGTAGCGCCGGCCCAGGCCTGGTCCTTCGGCCCGGA
AGCGCTGCTGAACGTGTTCGACGGCGGCCGGCGCGCCGCCCTGAACGCGCATGCCCGCGCGGTTTATGACGAGGAGGTCG
CGCGCTATCGGCAGACGGTCCTCGATGCCTGCCGCGATGTCGAGGACAGCCTCGTCTCCCTGCGTCGTCTGGCCGAGGAA
TCCGCCACGCAGCAGCAGGCCGTCATCGCGGCGCAGGACGCGACGCATCGCGCGGGCGAACTCAATACCGGCGGGCTCGC
CAGCTACTACAACGTCATCCTCGCACGGAATATCGAACTGTCCGACCGGCTGTCTGAGGTCGATATCCGCGTGCGCCGGA
TGACGGCGTCGGTGGCGCTGATCAAGGCACTGGGCGGGGGATGGGGCGGATAA

Upstream 100 bases:

>100_bases
GGGTCATCCTCAACCCGCCATCCTCGCTGGCGGATGGCGAGCGCGTGCATGTCGCATCCCCGGCCCCTGCCCAGGCGGCA
GCCAGGCCGGACCGGCATCC

Downstream 100 bases:

>100_bases
AGCAGATCGTGATGAGGTGGGATCACCTCATCACGCGCTCTAAGGTTTGGGGGCCACCATCGCGAAGATCGCCCCTTGCG
GGTCCCGGCACTGGGCGATC

Product: toluene efflux pump outer membrane protein ttgC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MMSCHSRAWRVLMLLAAMVPAACDLAPRYAPPVAPVPASFKERDGWALAVPGDDVPKGPWWRIFHDPVLDALEDRVTIAN
QDLRVAVAQYDEARADARTAQAGYYPTLDFTGSASRSGLSRETANVFNKSTFNSYSLGLDLQYEVDVWGRVRNTAKAGRA
RAQASAGDLATVDLSLHAELATDYFTLRGYDAMQAVLDQTVGNYRHALALTQAQFDVGYAAQPDVSAATAQLDGLLTQAA
DNRLRRAMLEHAIAILTGQPPATFAVAARSLDSAPPPIAPGLPVALLQRRPDIAAAERRVAAANADIGVARAAYFPAFNI
NAMMGVQAAMPNHLLVAPAQAWSFGPEALLNVFDGGRRAALNAHARAVYDEEVARYRQTVLDACRDVEDSLVSLRRLAEE
SATQQQAVIAAQDATHRAGELNTGGLASYYNVILARNIELSDRLSEVDIRVRRMTASVALIKALGGGWGG

Sequences:

>Translated_470_residues
MMSCHSRAWRVLMLLAAMVPAACDLAPRYAPPVAPVPASFKERDGWALAVPGDDVPKGPWWRIFHDPVLDALEDRVTIAN
QDLRVAVAQYDEARADARTAQAGYYPTLDFTGSASRSGLSRETANVFNKSTFNSYSLGLDLQYEVDVWGRVRNTAKAGRA
RAQASAGDLATVDLSLHAELATDYFTLRGYDAMQAVLDQTVGNYRHALALTQAQFDVGYAAQPDVSAATAQLDGLLTQAA
DNRLRRAMLEHAIAILTGQPPATFAVAARSLDSAPPPIAPGLPVALLQRRPDIAAAERRVAAANADIGVARAAYFPAFNI
NAMMGVQAAMPNHLLVAPAQAWSFGPEALLNVFDGGRRAALNAHARAVYDEEVARYRQTVLDACRDVEDSLVSLRRLAEE
SATQQQAVIAAQDATHRAGELNTGGLASYYNVILARNIELSDRLSEVDIRVRRMTASVALIKALGGGWGG
>Mature_470_residues
MMSCHSRAWRVLMLLAAMVPAACDLAPRYAPPVAPVPASFKERDGWALAVPGDDVPKGPWWRIFHDPVLDALEDRVTIAN
QDLRVAVAQYDEARADARTAQAGYYPTLDFTGSASRSGLSRETANVFNKSTFNSYSLGLDLQYEVDVWGRVRNTAKAGRA
RAQASAGDLATVDLSLHAELATDYFTLRGYDAMQAVLDQTVGNYRHALALTQAQFDVGYAAQPDVSAATAQLDGLLTQAA
DNRLRRAMLEHAIAILTGQPPATFAVAARSLDSAPPPIAPGLPVALLQRRPDIAAAERRVAAANADIGVARAAYFPAFNI
NAMMGVQAAMPNHLLVAPAQAWSFGPEALLNVFDGGRRAALNAHARAVYDEEVARYRQTVLDACRDVEDSLVSLRRLAEE
SATQQQAVIAAQDATHRAGELNTGGLASYYNVILARNIELSDRLSEVDIRVRRMTASVALIKALGGGWGG

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=462, Percent_Identity=28.7878787878788, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI2367348, Length=482, Percent_Identity=28.2157676348548, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50519; Mature: 50519

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSCHSRAWRVLMLLAAMVPAACDLAPRYAPPVAPVPASFKERDGWALAVPGDDVPKGPW
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
WRIFHDPVLDALEDRVTIANQDLRVAVAQYDEARADARTAQAGYYPTLDFTGSASRSGLS
EEEHHHHHHHHHHHHHEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RETANVFNKSTFNSYSLGLDLQYEVDVWGRVRNTAKAGRARAQASAGDLATVDLSLHAEL
HHHHHHHHCCCCCCEEECEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEHHH
ATDYFTLRGYDAMQAVLDQTVGNYRHALALTQAQFDVGYAAQPDVSAATAQLDGLLTQAA
HHCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
DNRLRRAMLEHAIAILTGQPPATFAVAARSLDSAPPPIAPGLPVALLQRRPDIAAAERRV
HHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHH
AAANADIGVARAAYFPAFNINAMMGVQAAMPNHLLVAPAQAWSFGPEALLNVFDGGRRAA
HHCCCCCHHHHHHHCCCCCCCHHHHHHHCCCCCEEEECHHHHCCCHHHHHHHHCCCCEEE
LNAHARAVYDEEVARYRQTVLDACRDVEDSLVSLRRLAEESATQQQAVIAAQDATHRAGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCC
LNTGGLASYYNVILARNIELSDRLSEVDIRVRRMTASVALIKALGGGWGG
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMSCHSRAWRVLMLLAAMVPAACDLAPRYAPPVAPVPASFKERDGWALAVPGDDVPKGPW
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
WRIFHDPVLDALEDRVTIANQDLRVAVAQYDEARADARTAQAGYYPTLDFTGSASRSGLS
EEEHHHHHHHHHHHHHEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RETANVFNKSTFNSYSLGLDLQYEVDVWGRVRNTAKAGRARAQASAGDLATVDLSLHAEL
HHHHHHHHCCCCCCEEECEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEHHH
ATDYFTLRGYDAMQAVLDQTVGNYRHALALTQAQFDVGYAAQPDVSAATAQLDGLLTQAA
HHCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
DNRLRRAMLEHAIAILTGQPPATFAVAARSLDSAPPPIAPGLPVALLQRRPDIAAAERRV
HHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHH
AAANADIGVARAAYFPAFNINAMMGVQAAMPNHLLVAPAQAWSFGPEALLNVFDGGRRAA
HHCCCCCHHHHHHHCCCCCCCHHHHHHHCCCCCEEEECHHHHCCCHHHHHHHHCCCCEEE
LNAHARAVYDEEVARYRQTVLDACRDVEDSLVSLRRLAEESATQQQAVIAAQDATHRAGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCC
LNTGGLASYYNVILARNIELSDRLSEVDIRVRRMTASVALIKALGGGWGG
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]