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The map label for this gene is mdtA [H]

Identifier: 162146388

GI number: 162146388

Start: 571258

End: 572439

Strand: Direct

Name: mdtA [H]

Synonym: GDI_0563

Alternate gene names: 162146388

Gene position: 571258-572439 (Clockwise)

Preceding gene: 162146387

Following gene: 162146389

Centisome position: 14.48

GC content: 70.73

Gene sequence:

>1182_bases
GTGACCGAGGGGCCAAAGGCGGGGCGTGGCCGCGCCGGGCTGCTGCTGGCCGGTCTTCTTCTGGTCGCGATCGGCGTTGC
CGGCTGGGGGATCTGGTCGCGGGTCCATGCCGGACGCAGGCTGGCGCGGGCGACCGATGACGCCGCCGTCGCGACGGTGG
CCGTGGTCCCGGCCCAGGCCGGCCCGGATGTCGAGGAGATCGTGCTGCCCGGCAGCGTCAGCGCCGCGTACGACACGCCG
ATCTATGCGCGGACCAGCGGATATATCCAGCGCTGGTATACCGATATCGGAACGCGGGTGAAAGCGGGCGATCTGCTGGC
GACGATCGAATCCCCGGAAATCGACCAGCAGCTTCGCCAGGCGCGCGCCGACCTGATGACCGCGCGCGCCAACAACATGG
TGGCGCAGGCGACGGCCCGGCGGGTGCATGCCCTGCTGCCGACACGTTCGGTCTCCGCGCAGCAGAACGATCAGGCCGCC
AGCGACGCCGCCGCCCGCGCCGCCACCGTGGCCTCGAACGAGGCCAACGTGCAGCGGCTGGAACAATTGGTGGGGTTCGA
AAAAGTCGTGGCACCCTACGACGGTATCGTCACGGCGCGCGAGACCGACAATGGCAGCCTGATCACCGCCGGCAGCGGCA
GCGGCGCGGAACTGTTCCGCGTTACCGATACGAGCTGGCTGCGGGTCTATGTCCAGGTTCCGCAGACCTATGCGCCGGAT
ATCCGGATCGGCCTTCCGGTCGAACTCCGCTTTCCGGAATATCCGGGGCGCGCCTTCCCGGCCACGCTGACCCGCACGGC
GGGCGCGTTGCAGCCGGACGCCCGGACCCTGCTGGTGCAGCTTCGCGCCGACAACGCCCAGGGCGCGCTGCTGCCCGGCG
GCTATACCGAGGTCCATTTCAAGCTGCGCCGCGCGGATCGGGGCGTGCGGATTCCCGCCAACGCCCTGCTGTTCCGGGCC
GAAGGGCTGCGGGTCGCCACCCTGTCGCCGGACGGACGGGCCAGCCTGCACGCGATCACGCAGGGACGCGATTTCGGGAC
GACGGTCGAAATCCTGACCGGCATCGCCCCCGGGGACCGGGTCATCCTCAACCCGCCATCCTCGCTGGCGGATGGCGAGC
GCGTGCATGTCGCATCCCCGGCCCCTGCCCAGGCGGCAGCCAGGCCGGACCGGCATCCGTGA

Upstream 100 bases:

>100_bases
GCTTCGCGACGACCGCGACGCTCGTGTTCGTGCCGGCGGTGTTCTCGATGATCCATGGCCGGGGTGCGCGCCCGCCCGCG
CCGGAAAACGGGGCCGCGTC

Downstream 100 bases:

>100_bases
TGTCATGCCACAGCCGCGCGTGGCGTGTCCTGATGCTGCTGGCGGCCATGGTACCGGCTGCCTGCGACCTGGCGCCGCGC
TATGCGCCGCCCGTGGCGCC

Product: multidrug resistance protein mdtA

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTEGPKAGRGRAGLLLAGLLLVAIGVAGWGIWSRVHAGRRLARATDDAAVATVAVVPAQAGPDVEEIVLPGSVSAAYDTP
IYARTSGYIQRWYTDIGTRVKAGDLLATIESPEIDQQLRQARADLMTARANNMVAQATARRVHALLPTRSVSAQQNDQAA
SDAAARAATVASNEANVQRLEQLVGFEKVVAPYDGIVTARETDNGSLITAGSGSGAELFRVTDTSWLRVYVQVPQTYAPD
IRIGLPVELRFPEYPGRAFPATLTRTAGALQPDARTLLVQLRADNAQGALLPGGYTEVHFKLRRADRGVRIPANALLFRA
EGLRVATLSPDGRASLHAITQGRDFGTTVEILTGIAPGDRVILNPPSSLADGERVHVASPAPAQAAARPDRHP

Sequences:

>Translated_393_residues
MTEGPKAGRGRAGLLLAGLLLVAIGVAGWGIWSRVHAGRRLARATDDAAVATVAVVPAQAGPDVEEIVLPGSVSAAYDTP
IYARTSGYIQRWYTDIGTRVKAGDLLATIESPEIDQQLRQARADLMTARANNMVAQATARRVHALLPTRSVSAQQNDQAA
SDAAARAATVASNEANVQRLEQLVGFEKVVAPYDGIVTARETDNGSLITAGSGSGAELFRVTDTSWLRVYVQVPQTYAPD
IRIGLPVELRFPEYPGRAFPATLTRTAGALQPDARTLLVQLRADNAQGALLPGGYTEVHFKLRRADRGVRIPANALLFRA
EGLRVATLSPDGRASLHAITQGRDFGTTVEILTGIAPGDRVILNPPSSLADGERVHVASPAPAQAAARPDRHP
>Mature_392_residues
TEGPKAGRGRAGLLLAGLLLVAIGVAGWGIWSRVHAGRRLARATDDAAVATVAVVPAQAGPDVEEIVLPGSVSAAYDTPI
YARTSGYIQRWYTDIGTRVKAGDLLATIESPEIDQQLRQARADLMTARANNMVAQATARRVHALLPTRSVSAQQNDQAAS
DAAARAATVASNEANVQRLEQLVGFEKVVAPYDGIVTARETDNGSLITAGSGSGAELFRVTDTSWLRVYVQVPQTYAPDI
RIGLPVELRFPEYPGRAFPATLTRTAGALQPDARTLLVQLRADNAQGALLPGGYTEVHFKLRRADRGVRIPANALLFRAE
GLRVATLSPDGRASLHAITQGRDFGTTVEILTGIAPGDRVILNPPSSLADGERVHVASPAPAQAAARPDRHP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=350, Percent_Identity=26.8571428571429, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87081796, Length=332, Percent_Identity=24.6987951807229, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789665, Length=343, Percent_Identity=25.0728862973761, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41626; Mature: 41494

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGPKAGRGRAGLLLAGLLLVAIGVAGWGIWSRVHAGRRLARATDDAAVATVAVVPAQA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
GPDVEEIVLPGSVSAAYDTPIYARTSGYIQRWYTDIGTRVKAGDLLATIESPEIDQQLRQ
CCCHHHEEECCCCCCCCCCCEEEECCHHHHHHHHHHCCEEECCCEEEEECCCCHHHHHHH
ARADLMTARANNMVAQATARRVHALLPTRSVSAQQNDQAASDAAARAATVASNEANVQRL
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH
EQLVGFEKVVAPYDGIVTARETDNGSLITAGSGSGAELFRVTDTSWLRVYVQVPQTYAPD
HHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCCEEEEEECCCEEEEEEECCCCCCCC
IRIGLPVELRFPEYPGRAFPATLTRTAGALQPDARTLLVQLRADNAQGALLPGGYTEVHF
EEECCEEEEECCCCCCCCCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEE
KLRRADRGVRIPANALLFRAEGLRVATLSPDGRASLHAITQGRDFGTTVEILTGIAPGDR
EEEECCCCCCCCCHHEEEEECCCEEEEECCCCCCEEEEEECCCCCCCHHHHHHCCCCCCE
VILNPPSSLADGERVHVASPAPAQAAARPDRHP
EEECCCCCCCCCCEEEECCCCCHHHCCCCCCCC
>Mature Secondary Structure 
TEGPKAGRGRAGLLLAGLLLVAIGVAGWGIWSRVHAGRRLARATDDAAVATVAVVPAQA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
GPDVEEIVLPGSVSAAYDTPIYARTSGYIQRWYTDIGTRVKAGDLLATIESPEIDQQLRQ
CCCHHHEEECCCCCCCCCCCEEEECCHHHHHHHHHHCCEEECCCEEEEECCCCHHHHHHH
ARADLMTARANNMVAQATARRVHALLPTRSVSAQQNDQAASDAAARAATVASNEANVQRL
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH
EQLVGFEKVVAPYDGIVTARETDNGSLITAGSGSGAELFRVTDTSWLRVYVQVPQTYAPD
HHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCCEEEEEECCCEEEEEEECCCCCCCC
IRIGLPVELRFPEYPGRAFPATLTRTAGALQPDARTLLVQLRADNAQGALLPGGYTEVHF
EEECCEEEEECCCCCCCCCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEE
KLRRADRGVRIPANALLFRAEGLRVATLSPDGRASLHAITQGRDFGTTVEILTGIAPGDR
EEEECCCCCCCCCHHEEEEECCCEEEEECCCCCCEEEEEECCCCCCCHHHHHHCCCCCCE
VILNPPSSLADGERVHVASPAPAQAAARPDRHP
EEECCCCCCCCCCEEEECCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA