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The map label for this gene is qor [H]

Identifier: 162146348

GI number: 162146348

Start: 516582

End: 517571

Strand: Reverse

Name: qor [H]

Synonym: GDI_0523

Alternate gene names: 162146348

Gene position: 517571-516582 (Counterclockwise)

Preceding gene: 162146350

Following gene: 162146347

Centisome position: 13.12

GC content: 71.92

Gene sequence:

>990_bases
ATGCGCGCGGTCGTCGTCCGTGATCCCGGACCGCCCGATGCCATGGAACTGGCGGACCTGCCCCTGCCCCGGCCCGGCCC
GGGCGAAGTCCTGGTCCGGGTCATGGCCGCCGGCGTGAACCGGCCCGACATCATGCAGCGCCAGGGCCTGTATCCACCGC
CGCCCGGCGCCAGCCCGATCCTGGGGCTGGAAATCGCGGGCGAGGTCGTCGCGGGCCGTCCCGACGGGTCCTGGCCCGCG
ACCGGCACGCGCGTCTGCGCCCTGACCAATGGCGGCGGGTATGCCGAATATTGCGCAGTGCCGGCCGGACAATGCCTGCC
CTGGCCCGAAGGGTATGACGCCATTCGCGCCGCCGCCCTGCCGGAGACGTTCTTTACCGCTTGGTCGAACCTGGCCATGA
CCGCGCACCTGGCCGCCGGCGAGTCCGTGCTGATCCATGGCGGCAGCGGCGGCATCGGCACCGCCGCGATCCAGACCGCC
CGGGCGCTGCGGGCGATTCCGTACGTCACGGTGGGGTCGGCCGAAAAGGCCGCGCTGTGCGTGCGGCTGGGCGCCGAGGC
CGCGATCGACTACCGCAGCGAGAATTTCGTCGCGCGAATCGGCACCCTGACCGGCGGGCGGGGCGTGGACGTGGTACTGG
ACGTGATCGGCGGCCCGTATCTGGACCGCAACCTGCGCTGCCTGGCCCCGGACGGGCGCCTGGTCATCATCGCGCTGCAG
GGTGGGGCGAAGGCGCAGGATGTGGGCGTGGCCCGCATCATGACCCGCCGCCTGACGGTGACGGGCACGACGCTGCGCCC
CCGTGACACGGCATACAAGGCGCAGGTCGCGGACGGGCTGCGCCGGACGATCTGGCCCGGGCTGGCGGACGGGACGATCG
CGCCGGTGATTCACGCCACCTTCCCCTTTGCGCGCGTCGCCGAAGCCCATAAGCTCATGGAATCGGGTGCCCATTCGGGC
AAGATCGTCCTGAGCCTGGTGCCGGCATAA

Upstream 100 bases:

>100_bases
TACGCCATAACCGTCGCAGCACCATTCCTGCTGACCATTCCTGTTGCCGGAGAGTCGCCCCGTGTCCGCTCCCTCGCTAT
CCCCTGGCCTGCCCCACCAC

Downstream 100 bases:

>100_bases
AAGGGAAGGACCATGCCATCGTGCTGCTGAACGTCATCGCGCGCGGGCCCGAGGACCAGTCGGGGGGCGAGTCCGCGCGG
CCGCCCATCGTCCTGCTGCA

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MRAVVVRDPGPPDAMELADLPLPRPGPGEVLVRVMAAGVNRPDIMQRQGLYPPPPGASPILGLEIAGEVVAGRPDGSWPA
TGTRVCALTNGGGYAEYCAVPAGQCLPWPEGYDAIRAAALPETFFTAWSNLAMTAHLAAGESVLIHGGSGGIGTAAIQTA
RALRAIPYVTVGSAEKAALCVRLGAEAAIDYRSENFVARIGTLTGGRGVDVVLDVIGGPYLDRNLRCLAPDGRLVIIALQ
GGAKAQDVGVARIMTRRLTVTGTTLRPRDTAYKAQVADGLRRTIWPGLADGTIAPVIHATFPFARVAEAHKLMESGAHSG
KIVLSLVPA

Sequences:

>Translated_329_residues
MRAVVVRDPGPPDAMELADLPLPRPGPGEVLVRVMAAGVNRPDIMQRQGLYPPPPGASPILGLEIAGEVVAGRPDGSWPA
TGTRVCALTNGGGYAEYCAVPAGQCLPWPEGYDAIRAAALPETFFTAWSNLAMTAHLAAGESVLIHGGSGGIGTAAIQTA
RALRAIPYVTVGSAEKAALCVRLGAEAAIDYRSENFVARIGTLTGGRGVDVVLDVIGGPYLDRNLRCLAPDGRLVIIALQ
GGAKAQDVGVARIMTRRLTVTGTTLRPRDTAYKAQVADGLRRTIWPGLADGTIAPVIHATFPFARVAEAHKLMESGAHSG
KIVLSLVPA
>Mature_329_residues
MRAVVVRDPGPPDAMELADLPLPRPGPGEVLVRVMAAGVNRPDIMQRQGLYPPPPGASPILGLEIAGEVVAGRPDGSWPA
TGTRVCALTNGGGYAEYCAVPAGQCLPWPEGYDAIRAAALPETFFTAWSNLAMTAHLAAGESVLIHGGSGGIGTAAIQTA
RALRAIPYVTVGSAEKAALCVRLGAEAAIDYRSENFVARIGTLTGGRGVDVVLDVIGGPYLDRNLRCLAPDGRLVIIALQ
GGAKAQDVGVARIMTRRLTVTGTTLRPRDTAYKAQVADGLRRTIWPGLADGTIAPVIHATFPFARVAEAHKLMESGAHSG
KIVLSLVPA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=331, Percent_Identity=41.6918429003021, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI22538444, Length=331, Percent_Identity=41.6918429003021, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=31.6109422492401, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=31.6109422492401, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=30.8681672025724, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI41872631, Length=315, Percent_Identity=31.1111111111111, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI194239676, Length=329, Percent_Identity=30.3951367781155, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI28557745, Length=342, Percent_Identity=29.8245614035088, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI24308257, Length=346, Percent_Identity=27.7456647398844, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI197927207, Length=198, Percent_Identity=29.7979797979798, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI47519420, Length=344, Percent_Identity=29.3604651162791, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1790485, Length=319, Percent_Identity=30.4075235109718, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1788075, Length=291, Percent_Identity=25.7731958762887, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=334, Percent_Identity=29.3413173652695, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI212642053, Length=313, Percent_Identity=29.3929712460064, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319520, Length=339, Percent_Identity=24.188790560472, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=342, Percent_Identity=25.1461988304094, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=342, Percent_Identity=24.8538011695906, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=339, Percent_Identity=23.3038348082596, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=341, Percent_Identity=25.8064516129032, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19920632, Length=273, Percent_Identity=27.4725274725275, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI221330659, Length=273, Percent_Identity=27.4725274725275, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24581345, Length=275, Percent_Identity=28.3636363636364, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34156; Mature: 34156

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVVVRDPGPPDAMELADLPLPRPGPGEVLVRVMAAGVNRPDIMQRQGLYPPPPGASPI
CCEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCE
LGLEIAGEVVAGRPDGSWPATGTRVCALTNGGGYAEYCAVPAGQCLPWPEGYDAIRAAAL
EEEEECCEEEECCCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCCCCCCCHHHHHHHHC
PETFFTAWSNLAMTAHLAAGESVLIHGGSGGIGTAAIQTARALRAIPYVTVGSAEKAALC
CHHHHHHHHHHEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCCCEEEE
VRLGAEAAIDYRSENFVARIGTLTGGRGVDVVLDVIGGPYLDRNLRCLAPDGRLVIIALQ
EEECCHHEEEECCCCEEEEEEECCCCCCCEEHEEECCCCCCCCCCEEECCCCCEEEEEEC
GGAKAQDVGVARIMTRRLTVTGTTLRPRDTAYKAQVADGLRRTIWPGLADGTIAPVIHAT
CCCCCHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
FPFARVAEAHKLMESGAHSGKIVLSLVPA
CCHHHHHHHHHHHHCCCCCCEEEEEEECC
>Mature Secondary Structure
MRAVVVRDPGPPDAMELADLPLPRPGPGEVLVRVMAAGVNRPDIMQRQGLYPPPPGASPI
CCEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCE
LGLEIAGEVVAGRPDGSWPATGTRVCALTNGGGYAEYCAVPAGQCLPWPEGYDAIRAAAL
EEEEECCEEEECCCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCCCCCCCHHHHHHHHC
PETFFTAWSNLAMTAHLAAGESVLIHGGSGGIGTAAIQTARALRAIPYVTVGSAEKAALC
CHHHHHHHHHHEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCCCEEEE
VRLGAEAAIDYRSENFVARIGTLTGGRGVDVVLDVIGGPYLDRNLRCLAPDGRLVIIALQ
EEECCHHEEEECCCCEEEEEEECCCCCCCEEHEEECCCCCCCCCCEEECCCCCEEEEEEC
GGAKAQDVGVARIMTRRLTVTGTTLRPRDTAYKAQVADGLRRTIWPGLADGTIAPVIHAT
CCCCCHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
FPFARVAEAHKLMESGAHSGKIVLSLVPA
CCHHHHHHHHHHHHCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]