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The map label for this gene is kamA [H]

Identifier: 162146333

GI number: 162146333

Start: 504986

End: 506134

Strand: Reverse

Name: kamA [H]

Synonym: GDI_0508

Alternate gene names: 162146333

Gene position: 506134-504986 (Counterclockwise)

Preceding gene: 162146337

Following gene: 162146332

Centisome position: 12.83

GC content: 72.58

Gene sequence:

>1149_bases
ATGACACGATCGGTCAACCTTCCCGAGGATACGCCCGCCCCGCCCGGCGCCGCACCGCCCGGCGCCGAGCCGGGCCGGAC
AGTGCGCGATGTGGCCGGCCTGGTGGCGGCCGGCCTGGTTTCCCCCGGCGCGGTGCCGGCGCTGGAAGAGGTCGCCCGGC
AGTACGCCACCGCCATCCCGCCCGCCTTCGCCGGGCTGATCACCCGTCCCGACGATCCGATCGGGTTGCAGGTCGTCCCG
GACGCGTCCGAACTGACGATTGCCCCCCATGAACGGATGGACCCGATCGGCGACGACGCGCTGTCGCCCGTGCCGGGCAT
CGTCCACCGCTATGCCGACCGCGCGCTGCTGAAGCCGCTGCTGGTCTGTCCGCTTTATTGCCGGTTCTGCTTCCGGCGGG
AACATGTGGGCCCCGATGGCGGCGTGCTGGACGATGCGGCGCTGGAGCGCGCGCTGGACTGGCTGCGCACCCACCCCGCC
ATCCGCGAGGTGATCCTGACCGGGGGCGACCCGCTGATGCTGTCGCCCCGCCGCCTGGGCGCGATCGTCCGGGCGCTGGG
GGACATGCCCCATGTCACCACCATCCGTATCCACAGCCGCGTGCCGGTGGCCGACCCCGGCCGCATCACCGACGCGCTGG
CCGACGCGATGGAAACCGACCGCGCGATGTGGGTGGTGGTGCATGCCAACCATGCCCGCGAATTCACCCCGGCCGCCCGC
GCGGCCCTGCGGCGCATCCAGGCGCGGGCCATTCCGGTACTGGGCCAGTCGGTCCTGCTGCGGGGGGTCAATGACAGCGT
CGCGGCGCTGGAGGCCCTGTTCCGCGCCATGGTCGAGGCCCGGATGAAGCCGTACTACCTGCATCAGCTGGACGCCGCCC
CCGGCACCGCGCGTTTCCATGTGCCGATCGCCGAGGGACGGCGCCTGCTGGCCGGGCTGCGCGGCCGGGTGACGGGCCTG
GCATGGCCGACCTATACGCTGGATATTCCGGGCGGATACGGCAAGGTGCCGCTGGGTCCGGATTACCTGGAACCGGAGGG
GCCGGCGCCGGACGGGACGGGCCTGTCGGTGCGCGATCCGGCGGGGGGACGACACAAACTGGAGGCTGAATCGGCGGCCA
ACCTTGCCCTCGGCGCCCGAGAGGGTTAG

Upstream 100 bases:

>100_bases
AGCGCCAGCCGCCCCGCGATGCGATCGGGGTCGTGATGGGGGCTGTCGGTCATGCGCGACTCCTGTTGCAGGACGAAATC
CGGTCGAGTAGAGCCAGCCG

Downstream 100 bases:

>100_bases
AAGCCCGCCTTCCATACCCATCAATCGTTCATACCAACACAACCAGACAGGCCCCCCCATGAAACAGCAGGCGAACCTGA
TCCGTGCCGGACAGGTCATC

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MTRSVNLPEDTPAPPGAAPPGAEPGRTVRDVAGLVAAGLVSPGAVPALEEVARQYATAIPPAFAGLITRPDDPIGLQVVP
DASELTIAPHERMDPIGDDALSPVPGIVHRYADRALLKPLLVCPLYCRFCFRREHVGPDGGVLDDAALERALDWLRTHPA
IREVILTGGDPLMLSPRRLGAIVRALGDMPHVTTIRIHSRVPVADPGRITDALADAMETDRAMWVVVHANHAREFTPAAR
AALRRIQARAIPVLGQSVLLRGVNDSVAALEALFRAMVEARMKPYYLHQLDAAPGTARFHVPIAEGRRLLAGLRGRVTGL
AWPTYTLDIPGGYGKVPLGPDYLEPEGPAPDGTGLSVRDPAGGRHKLEAESAANLALGAREG

Sequences:

>Translated_382_residues
MTRSVNLPEDTPAPPGAAPPGAEPGRTVRDVAGLVAAGLVSPGAVPALEEVARQYATAIPPAFAGLITRPDDPIGLQVVP
DASELTIAPHERMDPIGDDALSPVPGIVHRYADRALLKPLLVCPLYCRFCFRREHVGPDGGVLDDAALERALDWLRTHPA
IREVILTGGDPLMLSPRRLGAIVRALGDMPHVTTIRIHSRVPVADPGRITDALADAMETDRAMWVVVHANHAREFTPAAR
AALRRIQARAIPVLGQSVLLRGVNDSVAALEALFRAMVEARMKPYYLHQLDAAPGTARFHVPIAEGRRLLAGLRGRVTGL
AWPTYTLDIPGGYGKVPLGPDYLEPEGPAPDGTGLSVRDPAGGRHKLEAESAANLALGAREG
>Mature_381_residues
TRSVNLPEDTPAPPGAAPPGAEPGRTVRDVAGLVAAGLVSPGAVPALEEVARQYATAIPPAFAGLITRPDDPIGLQVVPD
ASELTIAPHERMDPIGDDALSPVPGIVHRYADRALLKPLLVCPLYCRFCFRREHVGPDGGVLDDAALERALDWLRTHPAI
REVILTGGDPLMLSPRRLGAIVRALGDMPHVTTIRIHSRVPVADPGRITDALADAMETDRAMWVVVHANHAREFTPAARA
ALRRIQARAIPVLGQSVLLRGVNDSVAALEALFRAMVEARMKPYYLHQLDAAPGTARFHVPIAEGRRLLAGLRGRVTGLA
WPTYTLDIPGGYGKVPLGPDYLEPEGPAPDGTGLSVRDPAGGRHKLEAESAANLALGAREG

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=288, Percent_Identity=36.4583333333333, Blast_Score=181, Evalue=9e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 40598; Mature: 40467

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSVNLPEDTPAPPGAAPPGAEPGRTVRDVAGLVAAGLVSPGAVPALEEVARQYATAIP
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
PAFAGLITRPDDPIGLQVVPDASELTIAPHERMDPIGDDALSPVPGIVHRYADRALLKPL
HHHHHHCCCCCCCCCEEECCCCCCEEECCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LVCPLYCRFCFRREHVGPDGGVLDDAALERALDWLRTHPAIREVILTGGDPLMLSPRRLG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCEEECHHHHH
AIVRALGDMPHVTTIRIHSRVPVADPGRITDALADAMETDRAMWVVVHANHAREFTPAAR
HHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHH
AALRRIQARAIPVLGQSVLLRGVNDSVAALEALFRAMVEARMKPYYLHQLDAAPGTARFH
HHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEE
VPIAEGRRLLAGLRGRVTGLAWPTYTLDIPGGYGKVPLGPDYLEPEGPAPDGTGLSVRDP
EEHHHHHHHHHHHHHCEEEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
AGGRHKLEAESAANLALGAREG
CCCCCEECHHHHCCCCCCCCCC
>Mature Secondary Structure 
TRSVNLPEDTPAPPGAAPPGAEPGRTVRDVAGLVAAGLVSPGAVPALEEVARQYATAIP
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
PAFAGLITRPDDPIGLQVVPDASELTIAPHERMDPIGDDALSPVPGIVHRYADRALLKPL
HHHHHHCCCCCCCCCEEECCCCCCEEECCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LVCPLYCRFCFRREHVGPDGGVLDDAALERALDWLRTHPAIREVILTGGDPLMLSPRRLG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCEEECHHHHH
AIVRALGDMPHVTTIRIHSRVPVADPGRITDALADAMETDRAMWVVVHANHAREFTPAAR
HHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHH
AALRRIQARAIPVLGQSVLLRGVNDSVAALEALFRAMVEARMKPYYLHQLDAAPGTARFH
HHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEE
VPIAEGRRLLAGLRGRVTGLAWPTYTLDIPGGYGKVPLGPDYLEPEGPAPDGTGLSVRDP
EEHHHHHHHHHHHHHCEEEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
AGGRHKLEAESAANLALGAREG
CCCCCEECHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]