Click here to switch to the map view.

The map label for this gene is efp

Identifier: 162146332

GI number: 162146332

Start: 504361

End: 504927

Strand: Reverse

Name: efp

Synonym: GDI_0507

Alternate gene names: 162146332

Gene position: 504927-504361 (Counterclockwise)

Preceding gene: 162146333

Following gene: 162146331

Centisome position: 12.8

GC content: 64.55

Gene sequence:

>567_bases
ATGAAACAGCAGGCGAACCTGATCCGTGCCGGACAGGTCATCGAGCACGACGGCCGTCGCTGGACTGTCCTGAAGCAGCA
GATCATCACCCCCGGCAAGGGCGGCGCGTTCATCCAGGTGGAAATGCGCGACCTGAAGACCGGCAACAAGACGAACGAGC
GCTGGCGCACCGCCGACACCGTCGAGCGTCTGCTGACCGAGGAAAAGGAATATACCTATTCCTACATGGACGGCGACAAC
ATCGTCCTGATGGACCCCGAGACGTTCGAGCAGACGCTGCTGCCGCTGGACCTGCTGGGCGACCAGGCGCCGTTCCTGCA
GGACAACATGGTGCTGGTGGTCAACCTGGTCGAAGGCGACCCGGTGGGCGTGACGCTGCCGGCGCAGGTCACGCTGGAGA
TCATCGAGGCCGACCCCGTGGTGAAGGGCCAGACCGCCAGCTCGTCCTACAAGCCGGCCAAGCTGTCGAACGGCGTAAAG
ACCATGGTGCCGCCGTTCATCGAGGCCGGCGAGCGCATCGTCGTCCGCACCGAGGACGCCAGCTACGTGGAACGCGCGAA
GGGCTGA

Upstream 100 bases:

>100_bases
GAATCGGCGGCCAACCTTGCCCTCGGCGCCCGAGAGGGTTAGAAGCCCGCCTTCCATACCCATCAATCGTTCATACCAAC
ACAACCAGACAGGCCCCCCC

Downstream 100 bases:

>100_bases
GGCCCTTATCGCGTTCCAGCCCCCTTCCTCCGCCGAACAGACAGGACCGACCATCGTGGCCATGCGACTCTCTCCCCACA
TGACGGTGATGCAGAACGCG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKQQANLIRAGQVIEHDGRRWTVLKQQIITPGKGGAFIQVEMRDLKTGNKTNERWRTADTVERLLTEEKEYTYSYMDGDN
IVLMDPETFEQTLLPLDLLGDQAPFLQDNMVLVVNLVEGDPVGVTLPAQVTLEIIEADPVVKGQTASSSYKPAKLSNGVK
TMVPPFIEAGERIVVRTEDASYVERAKG

Sequences:

>Translated_188_residues
MKQQANLIRAGQVIEHDGRRWTVLKQQIITPGKGGAFIQVEMRDLKTGNKTNERWRTADTVERLLTEEKEYTYSYMDGDN
IVLMDPETFEQTLLPLDLLGDQAPFLQDNMVLVVNLVEGDPVGVTLPAQVTLEIIEADPVVKGQTASSSYKPAKLSNGVK
TMVPPFIEAGERIVVRTEDASYVERAKG
>Mature_188_residues
MKQQANLIRAGQVIEHDGRRWTVLKQQIITPGKGGAFIQVEMRDLKTGNKTNERWRTADTVERLLTEEKEYTYSYMDGDN
IVLMDPETFEQTLLPLDLLGDQAPFLQDNMVLVVNLVEGDPVGVTLPAQVTLEIIEADPVVKGQTASSSYKPAKLSNGVK
TMVPPFIEAGERIVVRTEDASYVERAKG

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=39.344262295082, Blast_Score=126, Evalue=9e-31,
Organism=Escherichia coli, GI87082061, Length=187, Percent_Identity=32.0855614973262, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_GLUDA (A9H6E1)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001600791.1
- RefSeq:   YP_002275894.1
- ProteinModelPortal:   A9H6E1
- SMR:   A9H6E1
- GeneID:   5791347
- GeneID:   6974910
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_1500
- HOGENOM:   HBG303311
- OMA:   FMDNEDY
- ProtClustDB:   PRK00529
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20947; Mature: 20947

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQQANLIRAGQVIEHDGRRWTVLKQQIITPGKGGAFIQVEMRDLKTGNKTNERWRTADT
CCCCCCHHHHCCEEECCCCEEEEEHHHHCCCCCCCEEEEEEEEECCCCCCCCCHHCCHHH
VERLLTEEKEYTYSYMDGDNIVLMDPETFEQTLLPLDLLGDQAPFLQDNMVLVVNLVEGD
HHHHHHCCCCEEEEEECCCEEEEECCHHHHHHHCCHHHCCCCCCCCCCCEEEEEEEECCC
PVGVTLPAQVTLEIIEADPVVKGQTASSSYKPAKLSNGVKTMVPPFIEAGERIVVRTEDA
CCCEEECCEEEEEEEECCCCCCCCCCCCCCCCHHHCCCCHHHCCHHHHCCCEEEEEECCH
SYVERAKG
HHHHHCCC
>Mature Secondary Structure
MKQQANLIRAGQVIEHDGRRWTVLKQQIITPGKGGAFIQVEMRDLKTGNKTNERWRTADT
CCCCCCHHHHCCEEECCCCEEEEEHHHHCCCCCCCEEEEEEEEECCCCCCCCCHHCCHHH
VERLLTEEKEYTYSYMDGDNIVLMDPETFEQTLLPLDLLGDQAPFLQDNMVLVVNLVEGD
HHHHHHCCCCEEEEEECCCEEEEECCHHHHHHHCCHHHCCCCCCCCCCCEEEEEEEECCC
PVGVTLPAQVTLEIIEADPVVKGQTASSSYKPAKLSNGVKTMVPPFIEAGERIVVRTEDA
CCCEEECCEEEEEEEECCCCCCCCCCCCCCCCHHHCCCCHHHCCHHHHCCCEEEEEECCH
SYVERAKG
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA