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The map label for this gene is irgA [H]

Identifier: 162146244

GI number: 162146244

Start: 416784

End: 419234

Strand: Reverse

Name: irgA [H]

Synonym: GDI_0419

Alternate gene names: 162146244

Gene position: 419234-416784 (Counterclockwise)

Preceding gene: 162146245

Following gene: 162146243

Centisome position: 10.63

GC content: 64.22

Gene sequence:

>2451_bases
GTGCGACGAACGACCATCCTTCTTTCCGCCACGACGGCACTGGTGACGATGGCGGGCCCTGCGGCGCCGAGCCGCGCCCA
CGCGCAGTCCGTGAGCGATACGACCGCCACGCCCACGCCCCCCGCGCCTTCGACCGTCATGCGCAAGGTCGCCAGGACCG
CGTCGGCATCGCCGGCCACGGATGGCGACAAGGACGAGCAGGTGATCGTCACCGGCACGCGCGATCCGCACCAGACCGCG
CGCAGCAGCGTCAGCCCGATCCAGGTCGTCACCGCGGCGCAGCTTGCCGCCACCGGGCAGGCCGACGTCCGCGACGCGCT
GATCCAGCTTGCGCCGTCCGTCGCGCGGTCCATCCGCGTGAACGGCAGCGCCAACATGACCGACGCGATCAGCCTGCGCG
GCCTGACGCCGAACCAGACCCTGGTCCTGGTGAACGGCAAGCGCCGGCACACCACGGCCGTCCTGTCGAACAACGCGGGG
CCCCAGCAGGGCGCGACGCCCGTCGATATCGACATGATTCCGGTTTCGGCCGTCGATCACATCGAAATCCTGCAGGACGG
CGCCGCCGCGCAATATGGTTCGGATGCGATCGCGGGCGTGGTCAACATCATCCTCAAGCACGATACGCACGGGCTGGAGG
CCCAGTCGCTGAATGGTGGGCGCTATGCGGGTGACGGCTTTACCTCCGGCGAATCGCTGAACTGGGGAACATCCCTGGCA
GGACGCGGATTTTTCGACCTGAACGCGGAATACAAATACCAGGACCACACATTCCGCGCCACGCCGGACAGCCGCACCGG
CCGCAACGACTTCATGGATATCGGCGACCCGCGCCAGCAGCGCGAGACGATCGGCTACAACATGGAATATGCCATCACCG
ACGATGTGAAGCTGTATTCCTTCGCGACCTATGGCCACCGGAACGGAGAAAGCTACCAGGATTACCGCGTCCCCACCGCC
AGCCTGCCCATGTACCCCTACGGATTCAGCCCGCAGGAAACCCTGGACGAGAACGATTACAGCGTGACCGTCGGTTTCAA
GGGCCGCAAGTTCAACTGGGACTGGGATTTGAGCACGACCTACGGCGGAGATTCCGAGCGGATGGGACTGTTCGACAGCA
TCAACACCGCAATGCTTCAGAATTTCGGCTCTTCGCCCACGCGATTCCATCTGATGTCGTTCAGCAACACCCAGTGGACG
ACCGATGCCGGCGTGCGCCGCGCCTTCGACGTCCCCCTGTTGGCAGCGCCGCTGAATCTGGCATTGGGCGCGCAATATCG
TTATGACAGCTACCATATCGGCGCGGGCGACATGGGATCGTATTACGGCACCGGCGCGTCGGCCTTCCATGGGCTGAGCC
CGAACAACGCCAGCGACAGCAACCGCGACGTGACGGCCGGATATATCGATGTTTCCACCCAGCTTCTGCCGAAATGGCAG
GTGGACCTGGCGGGTCGGTTCGAACATTACACCGACGCGGGCGATACCGAGACCGGCAAGGTTTCGTCGCGCTATGACGT
CAACCGGTATTTCGGCCTGCGCGGCACCGTCGCCAGCGGCTTCCGCGCCCCGACCCTGGCCGAGGAGCACTGGTCGAACA
TGTCCGTCGCCGCGACGACGGCCACCGGTTACATTCCCGTCGATTCCGCCGGGGCGCGACTGCTGGGCGCGAAGCCGCTG
AAGCCCGAACGGTCGACCAGCTTCAGCGCCGGCTTCGTCGTCAACCCGATCGACAACCTGCATGTAACGGTCGACGCCTA
CCAGATCGACCTGCGGGACCGGATCATGGCGGCCGGCGTCTATAACGGCGCCAGCGCCATCGAGGCGCTGGCGCTGAACG
GCTTCGCCATTCCCGCCGGGGTGACGGCGAACGCGGTCACGGCGCAATATTACGCCAATGCCGCCAGCACCCGCACGCGC
GGCCTGGACATCACGGCGAACTACCTGACGCGCCTGGGCCGGTACGGCCGCATCAACTGGGACGTGGCCGCCAATTTCAA
CCAGACCACCATCCGCCACGTGGCCGAGGACGGAAACGGCAATTCCCTGCTCAACGCGCAGCAGGAAGCCTACCTGACCA
GCTACACGCCCAGGAACCGGGTCATTTTCGGTGGCGTCTGGCATTACGGCGACCTGGACTTCACCGTCCATGAAATCCGC
TACGGCCATGCGACATCGCAACTGGAGTACTATACCGGCCCGCTGGCCTATTCGAACACGCAGTTCATGCGCTTCCTCAA
CCCGCCGCGCTACGAGACCAACCTCGTGATCGGCTACCAGGTCAGCCCGCGCTGGCATGTGGCGCTGGGCGCGAACAATG
TCGGCAATGCCAGGCAGAAGAAGATTCCGGAACAGTTCCGCTACCTTGGCGCCTATGCCTATGACGTGAATATCGAACAG
ATCGGCTACAATGGCGGGTTCTACTACTTCCAGGTCAACTTCAAGCTCTGA

Upstream 100 bases:

>100_bases
CGCCACGAATACTGGCGCAATGCATGTGTCTCGCGGTGCCTGACCGGATATCGGCTGCCGCAGGCGGTTTTTTTTCGATA
TTGCTTCAAGGAGCGGGAAA

Downstream 100 bases:

>100_bases
TCACACGCGGGCGGCAGGGAATGCCGCCCGCCGTTCGCAATTCAGCACATTGTGCGCGAGACCGCGACGAAACCGGCGTG
GCGTCGCTGGAAACCCATGC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 816; Mature: 816

Protein sequence:

>816_residues
MRRTTILLSATTALVTMAGPAAPSRAHAQSVSDTTATPTPPAPSTVMRKVARTASASPATDGDKDEQVIVTGTRDPHQTA
RSSVSPIQVVTAAQLAATGQADVRDALIQLAPSVARSIRVNGSANMTDAISLRGLTPNQTLVLVNGKRRHTTAVLSNNAG
PQQGATPVDIDMIPVSAVDHIEILQDGAAAQYGSDAIAGVVNIILKHDTHGLEAQSLNGGRYAGDGFTSGESLNWGTSLA
GRGFFDLNAEYKYQDHTFRATPDSRTGRNDFMDIGDPRQQRETIGYNMEYAITDDVKLYSFATYGHRNGESYQDYRVPTA
SLPMYPYGFSPQETLDENDYSVTVGFKGRKFNWDWDLSTTYGGDSERMGLFDSINTAMLQNFGSSPTRFHLMSFSNTQWT
TDAGVRRAFDVPLLAAPLNLALGAQYRYDSYHIGAGDMGSYYGTGASAFHGLSPNNASDSNRDVTAGYIDVSTQLLPKWQ
VDLAGRFEHYTDAGDTETGKVSSRYDVNRYFGLRGTVASGFRAPTLAEEHWSNMSVAATTATGYIPVDSAGARLLGAKPL
KPERSTSFSAGFVVNPIDNLHVTVDAYQIDLRDRIMAAGVYNGASAIEALALNGFAIPAGVTANAVTAQYYANAASTRTR
GLDITANYLTRLGRYGRINWDVAANFNQTTIRHVAEDGNGNSLLNAQQEAYLTSYTPRNRVIFGGVWHYGDLDFTVHEIR
YGHATSQLEYYTGPLAYSNTQFMRFLNPPRYETNLVIGYQVSPRWHVALGANNVGNARQKKIPEQFRYLGAYAYDVNIEQ
IGYNGGFYYFQVNFKL

Sequences:

>Translated_816_residues
MRRTTILLSATTALVTMAGPAAPSRAHAQSVSDTTATPTPPAPSTVMRKVARTASASPATDGDKDEQVIVTGTRDPHQTA
RSSVSPIQVVTAAQLAATGQADVRDALIQLAPSVARSIRVNGSANMTDAISLRGLTPNQTLVLVNGKRRHTTAVLSNNAG
PQQGATPVDIDMIPVSAVDHIEILQDGAAAQYGSDAIAGVVNIILKHDTHGLEAQSLNGGRYAGDGFTSGESLNWGTSLA
GRGFFDLNAEYKYQDHTFRATPDSRTGRNDFMDIGDPRQQRETIGYNMEYAITDDVKLYSFATYGHRNGESYQDYRVPTA
SLPMYPYGFSPQETLDENDYSVTVGFKGRKFNWDWDLSTTYGGDSERMGLFDSINTAMLQNFGSSPTRFHLMSFSNTQWT
TDAGVRRAFDVPLLAAPLNLALGAQYRYDSYHIGAGDMGSYYGTGASAFHGLSPNNASDSNRDVTAGYIDVSTQLLPKWQ
VDLAGRFEHYTDAGDTETGKVSSRYDVNRYFGLRGTVASGFRAPTLAEEHWSNMSVAATTATGYIPVDSAGARLLGAKPL
KPERSTSFSAGFVVNPIDNLHVTVDAYQIDLRDRIMAAGVYNGASAIEALALNGFAIPAGVTANAVTAQYYANAASTRTR
GLDITANYLTRLGRYGRINWDVAANFNQTTIRHVAEDGNGNSLLNAQQEAYLTSYTPRNRVIFGGVWHYGDLDFTVHEIR
YGHATSQLEYYTGPLAYSNTQFMRFLNPPRYETNLVIGYQVSPRWHVALGANNVGNARQKKIPEQFRYLGAYAYDVNIEQ
IGYNGGFYYFQVNFKL
>Mature_816_residues
MRRTTILLSATTALVTMAGPAAPSRAHAQSVSDTTATPTPPAPSTVMRKVARTASASPATDGDKDEQVIVTGTRDPHQTA
RSSVSPIQVVTAAQLAATGQADVRDALIQLAPSVARSIRVNGSANMTDAISLRGLTPNQTLVLVNGKRRHTTAVLSNNAG
PQQGATPVDIDMIPVSAVDHIEILQDGAAAQYGSDAIAGVVNIILKHDTHGLEAQSLNGGRYAGDGFTSGESLNWGTSLA
GRGFFDLNAEYKYQDHTFRATPDSRTGRNDFMDIGDPRQQRETIGYNMEYAITDDVKLYSFATYGHRNGESYQDYRVPTA
SLPMYPYGFSPQETLDENDYSVTVGFKGRKFNWDWDLSTTYGGDSERMGLFDSINTAMLQNFGSSPTRFHLMSFSNTQWT
TDAGVRRAFDVPLLAAPLNLALGAQYRYDSYHIGAGDMGSYYGTGASAFHGLSPNNASDSNRDVTAGYIDVSTQLLPKWQ
VDLAGRFEHYTDAGDTETGKVSSRYDVNRYFGLRGTVASGFRAPTLAEEHWSNMSVAATTATGYIPVDSAGARLLGAKPL
KPERSTSFSAGFVVNPIDNLHVTVDAYQIDLRDRIMAAGVYNGASAIEALALNGFAIPAGVTANAVTAQYYANAASTRTR
GLDITANYLTRLGRYGRINWDVAANFNQTTIRHVAEDGNGNSLLNAQQEAYLTSYTPRNRVIFGGVWHYGDLDFTVHEIR
YGHATSQLEYYTGPLAYSNTQFMRFLNPPRYETNLVIGYQVSPRWHVALGANNVGNARQKKIPEQFRYLGAYAYDVNIEQ
IGYNGGFYYFQVNFKL

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=612, Percent_Identity=21.7320261437909, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790405, Length=171, Percent_Identity=30.9941520467836, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 88863; Mature: 88863

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTTILLSATTALVTMAGPAAPSRAHAQSVSDTTATPTPPAPSTVMRKVARTASASPAT
CCCEEEEEEEEEEEEEECCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
DGDKDEQVIVTGTRDPHQTARSSVSPIQVVTAAQLAATGQADVRDALIQLAPSVARSIRV
CCCCCCEEEEECCCCHHHHHHCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHEEEE
NGSANMTDAISLRGLTPNQTLVLVNGKRRHTTAVLSNNAGPQQGATPVDIDMIPVSAVDH
CCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCH
IEILQDGAAAQYGSDAIAGVVNIILKHDTHGLEAQSLNGGRYAGDGFTSGESLNWGTSLA
HHHHHCCCCCCCCCHHHHHHHHHHEECCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCC
GRGFFDLNAEYKYQDHTFRATPDSRTGRNDFMDIGDPRQQRETIGYNMEYAITDDVKLYS
CCCEEECCCEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEECCEEEEE
FATYGHRNGESYQDYRVPTASLPMYPYGFSPQETLDENDYSVTVGFKGRKFNWDWDLSTT
EEECCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEECCCEECCEECCCCC
YGGDSERMGLFDSINTAMLQNFGSSPTRFHLMSFSNTQWTTDAGVRRAFDVPLLAAPLNL
CCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCEECCCCCHHHCCCCEEECCCCC
ALGAQYRYDSYHIGAGDMGSYYGTGASAFHGLSPNNASDSNRDVTAGYIDVSTQLLPKWQ
EECCEEECCCEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEEECCEECCCEE
VDLAGRFEHYTDAGDTETGKVSSRYDVNRYFGLRGTVASGFRAPTLAEEHWSNMSVAATT
EEECCCCCCCCCCCCCCCCCCCCCCCHHHEECCCCCCCCCCCCCCCHHHHCCCCEEEEEE
ATGYIPVDSAGARLLGAKPLKPERSTSFSAGFVVNPIDNLHVTVDAYQIDLRDRIMAAGV
EECEEEECCCCCEEECCCCCCCCCCCCCCCCEEECCCCCEEEEEEEEEECHHHHEEEEEC
YNGASAIEALALNGFAIPAGVTANAVTAQYYANAASTRTRGLDITANYLTRLGRYGRINW
CCCHHHHHHHEECCEEECCCCCCCCEEHHHHHCCCCCCCCCCEEEHHHHHHCCCCCCEEE
DVAANFNQTTIRHVAEDGNGNSLLNAQQEAYLTSYTPRNRVIFGGVWHYGDLDFTVHEIR
EEECCCCHHHHHHHHCCCCCCCEECCCHHHEEEECCCCCEEEEEEEEEECCCCEEEEEEE
YGHATSQLEYYTGPLAYSNTQFMRFLNPPRYETNLVIGYQVSPRWHVALGANNVGNARQK
ECCCCCCEEEEECCEEECCCHHHHHCCCCCCCCEEEEEEEECCEEEEEECCCCCCCHHHH
KIPEQFRYLGAYAYDVNIEQIGYNGGFYYFQVNFKL
HCHHHHHHHEEEEEEEEEEEEECCCCEEEEEEEEEC
>Mature Secondary Structure
MRRTTILLSATTALVTMAGPAAPSRAHAQSVSDTTATPTPPAPSTVMRKVARTASASPAT
CCCEEEEEEEEEEEEEECCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
DGDKDEQVIVTGTRDPHQTARSSVSPIQVVTAAQLAATGQADVRDALIQLAPSVARSIRV
CCCCCCEEEEECCCCHHHHHHCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHEEEE
NGSANMTDAISLRGLTPNQTLVLVNGKRRHTTAVLSNNAGPQQGATPVDIDMIPVSAVDH
CCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCH
IEILQDGAAAQYGSDAIAGVVNIILKHDTHGLEAQSLNGGRYAGDGFTSGESLNWGTSLA
HHHHHCCCCCCCCCHHHHHHHHHHEECCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCC
GRGFFDLNAEYKYQDHTFRATPDSRTGRNDFMDIGDPRQQRETIGYNMEYAITDDVKLYS
CCCEEECCCEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEECCEEEEE
FATYGHRNGESYQDYRVPTASLPMYPYGFSPQETLDENDYSVTVGFKGRKFNWDWDLSTT
EEECCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEECCCEECCEECCCCC
YGGDSERMGLFDSINTAMLQNFGSSPTRFHLMSFSNTQWTTDAGVRRAFDVPLLAAPLNL
CCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCEECCCCCHHHCCCCEEECCCCC
ALGAQYRYDSYHIGAGDMGSYYGTGASAFHGLSPNNASDSNRDVTAGYIDVSTQLLPKWQ
EECCEEECCCEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEEECCEECCCEE
VDLAGRFEHYTDAGDTETGKVSSRYDVNRYFGLRGTVASGFRAPTLAEEHWSNMSVAATT
EEECCCCCCCCCCCCCCCCCCCCCCCHHHEECCCCCCCCCCCCCCCHHHHCCCCEEEEEE
ATGYIPVDSAGARLLGAKPLKPERSTSFSAGFVVNPIDNLHVTVDAYQIDLRDRIMAAGV
EECEEEECCCCCEEECCCCCCCCCCCCCCCCEEECCCCCEEEEEEEEEECHHHHEEEEEC
YNGASAIEALALNGFAIPAGVTANAVTAQYYANAASTRTRGLDITANYLTRLGRYGRINW
CCCHHHHHHHEECCEEECCCCCCCCEEHHHHHCCCCCCCCCCEEEHHHHHHCCCCCCEEE
DVAANFNQTTIRHVAEDGNGNSLLNAQQEAYLTSYTPRNRVIFGGVWHYGDLDFTVHEIR
EEECCCCHHHHHHHHCCCCCCCEECCCHHHEEEECCCCCEEEEEEEEEECCCCEEEEEEE
YGHATSQLEYYTGPLAYSNTQFMRFLNPPRYETNLVIGYQVSPRWHVALGANNVGNARQK
ECCCCCCEEEEECCEEECCCHHHHHCCCCCCCCEEEEEEEECCEEEEEECCCCCCCHHHH
KIPEQFRYLGAYAYDVNIEQIGYNGGFYYFQVNFKL
HCHHHHHHHEEEEEEEEEEEEECCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]