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The map label for this gene is glpD [H]

Identifier: 162146093

GI number: 162146093

Start: 272578

End: 274200

Strand: Direct

Name: glpD [H]

Synonym: GDI_0262

Alternate gene names: 162146093

Gene position: 272578-274200 (Clockwise)

Preceding gene: 162146092

Following gene: 162146094

Centisome position: 6.91

GC content: 67.59

Gene sequence:

>1623_bases
ATGAATGTCCACCGCAAGGAGGCACGCATGTCATCCTTTCGACCTTTCCCCTCGCCATCATCCGCGACACCCATGCCGGG
CGACCGTGCCGCGTCCGGTGACGGACGATCGTACGACCTTCTGATCATCGGGGGCGGCGTCAACGGCTGCGGCATCGCGC
GCGACGCCGCCGGGCGCGGGGCGCGCGTCCTGCTGGTGGAACAGGACGACCTGGCCGGCCATACCTCGTCCGCCAGCACC
AAGCTGATCCATGGCGGCTTGCGCTATCTGGAATATTACGAATTCCGGCTGGTGCGCGAGGCGCTGATGGAGCGCGAGGT
GCTGCTGCGGATCGCGCCGCACATCATCTGGCCGATGCGCTTCGTGCTGCCGCATTCGAAGCTGGCGCGTCCGGTCTGGG
AACTGCGCGCGGGGCTGTTCCTCTACGATCACCTGGCCCTGACCATGACGCTGCCGCGCACCCGAAGCGTCACCTTCGCC
GACCATCCCAGCGGCGCCGTGCTGAAACCCGAATTCACCCGGGGGTTCATCTATTCCGACGGCTGGGTGCAGGACGCCCG
GCTGGTGGTCCTGAACGCCATGGACGCCGCCGCCCACGGCGCGGAAATCCGCACCCGCACCCGGTTCGTCTCGGCCACGA
GGGGCCGCGAGTCGTGGGAGGCCACGATCGCCGACCAGGAAACCGGCCGCACCGGCACCGTCCGGGCGCGCGCGCTGGTG
AACGCCACCGGCCCCTGGGTCGCCTCGGTGCTGCACGGCACGCTCGGGGTCGGGGGGAACAAGCAGGTGCGGCTGGTCAA
GGGCAGTCACATCGTGGTGCCGCGCCTGTTCGAGGGATCGCAGGCCTATATCCTGCAGAATCCCGACCGCCGCATCATCT
TCGTCATTCCGTACGAAAGCCGCTACACCCTCATCGGTACGACCGACATTCCGTGGGACGCGGACCCGGGCAAGGTCGCG
ATCTCGCCCGATGAAATCACGTATCTGTGCGACAGCGTGAACCGGTATTTCCGCAAGCCCGTCCAGCCGTCCGACGTCGT
ATGGAGCTATGCCGGCGTGCGCCCGCTCTTCGACGACCGGGCCAGCAGCGCCTCGGCCGTGACGCGCGACTACGTGCTGG
ATGTCGATACCGAGGGCGGGGCGCCCGTCCTTTCGATTTTCGGCGGAAAGATCACGACCTATCGCAGGCTGGCCGAACAC
GCGATCGAAAGGCTGGCCCCCCATGTGCGGTCGCTGCGCGCGGTGCCGTGGACCGGCCTGCACGCGCTGCCGGGCGGCGA
ATTCGTGGGGCGGAATTTTCTGGGCATGCTGGCGCAGTTGCGGGCGCGGGCACCCTGGCTGGACGAACACAATGCCTGGC
GCCTGATGCGCAATTACGGCACGCGGGCCTTCGACATCGCGGCCGGCGACGCCGCCGCGATGGGCCAGGATTTCGGATCC
GGACTGTACGCGCGCGAGGTCGATTACCTGATCGACCGCGAATGGGCCCGTTCGGCCGAGGATATCCTGTGGCGCCGGTC
CAAGCTCGGCCTCCTGTTTTCCGCCGGGCAGGTCGCGGAACTCGAATCCTATATCGCGCATCGCGGCAAGCCCGTGGAAT
CGCAGGTGGCGGATGTAGCCTAG

Upstream 100 bases:

>100_bases
TCGCTTTGGAACGCACGGGGCGTGAAACCTGATCGCATCCTCACGGATATGCGTTCGCCCGGGCGCGGAATCGAATTGAG
ACGCCCGGCCGTCTTCGGAT

Downstream 100 bases:

>100_bases
GACGTATCGGATTCGCCCCGCCCGAACAGGTCCCTGGAGACCAGGCATGAAGAAGCTCATCAACGCCCCCGACCGGGTCG
TCACCGAAGCCCTGGAGGGC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MNVHRKEARMSSFRPFPSPSSATPMPGDRAASGDGRSYDLLIIGGGVNGCGIARDAAGRGARVLLVEQDDLAGHTSSAST
KLIHGGLRYLEYYEFRLVREALMEREVLLRIAPHIIWPMRFVLPHSKLARPVWELRAGLFLYDHLALTMTLPRTRSVTFA
DHPSGAVLKPEFTRGFIYSDGWVQDARLVVLNAMDAAAHGAEIRTRTRFVSATRGRESWEATIADQETGRTGTVRARALV
NATGPWVASVLHGTLGVGGNKQVRLVKGSHIVVPRLFEGSQAYILQNPDRRIIFVIPYESRYTLIGTTDIPWDADPGKVA
ISPDEITYLCDSVNRYFRKPVQPSDVVWSYAGVRPLFDDRASSASAVTRDYVLDVDTEGGAPVLSIFGGKITTYRRLAEH
AIERLAPHVRSLRAVPWTGLHALPGGEFVGRNFLGMLAQLRARAPWLDEHNAWRLMRNYGTRAFDIAAGDAAAMGQDFGS
GLYAREVDYLIDREWARSAEDILWRRSKLGLLFSAGQVAELESYIAHRGKPVESQVADVA

Sequences:

>Translated_540_residues
MNVHRKEARMSSFRPFPSPSSATPMPGDRAASGDGRSYDLLIIGGGVNGCGIARDAAGRGARVLLVEQDDLAGHTSSAST
KLIHGGLRYLEYYEFRLVREALMEREVLLRIAPHIIWPMRFVLPHSKLARPVWELRAGLFLYDHLALTMTLPRTRSVTFA
DHPSGAVLKPEFTRGFIYSDGWVQDARLVVLNAMDAAAHGAEIRTRTRFVSATRGRESWEATIADQETGRTGTVRARALV
NATGPWVASVLHGTLGVGGNKQVRLVKGSHIVVPRLFEGSQAYILQNPDRRIIFVIPYESRYTLIGTTDIPWDADPGKVA
ISPDEITYLCDSVNRYFRKPVQPSDVVWSYAGVRPLFDDRASSASAVTRDYVLDVDTEGGAPVLSIFGGKITTYRRLAEH
AIERLAPHVRSLRAVPWTGLHALPGGEFVGRNFLGMLAQLRARAPWLDEHNAWRLMRNYGTRAFDIAAGDAAAMGQDFGS
GLYAREVDYLIDREWARSAEDILWRRSKLGLLFSAGQVAELESYIAHRGKPVESQVADVA
>Mature_540_residues
MNVHRKEARMSSFRPFPSPSSATPMPGDRAASGDGRSYDLLIIGGGVNGCGIARDAAGRGARVLLVEQDDLAGHTSSAST
KLIHGGLRYLEYYEFRLVREALMEREVLLRIAPHIIWPMRFVLPHSKLARPVWELRAGLFLYDHLALTMTLPRTRSVTFA
DHPSGAVLKPEFTRGFIYSDGWVQDARLVVLNAMDAAAHGAEIRTRTRFVSATRGRESWEATIADQETGRTGTVRARALV
NATGPWVASVLHGTLGVGGNKQVRLVKGSHIVVPRLFEGSQAYILQNPDRRIIFVIPYESRYTLIGTTDIPWDADPGKVA
ISPDEITYLCDSVNRYFRKPVQPSDVVWSYAGVRPLFDDRASSASAVTRDYVLDVDTEGGAPVLSIFGGKITTYRRLAEH
AIERLAPHVRSLRAVPWTGLHALPGGEFVGRNFLGMLAQLRARAPWLDEHNAWRLMRNYGTRAFDIAAGDAAAMGQDFGS
GLYAREVDYLIDREWARSAEDILWRRSKLGLLFSAGQVAELESYIAHRGKPVESQVADVA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=510, Percent_Identity=31.9607843137255, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI285002231, Length=510, Percent_Identity=31.9607843137255, Blast_Score=194, Evalue=1e-49,
Organism=Escherichia coli, GI2367226, Length=466, Percent_Identity=49.3562231759657, Blast_Score=443, Evalue=1e-125,
Organism=Escherichia coli, GI1788574, Length=500, Percent_Identity=26.8, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17509253, Length=552, Percent_Identity=31.1594202898551, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI115534726, Length=533, Percent_Identity=28.8930581613508, Blast_Score=170, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6322036, Length=600, Percent_Identity=28.3333333333333, Blast_Score=163, Evalue=5e-41,
Organism=Drosophila melanogaster, GI161077125, Length=516, Percent_Identity=30.6201550387597, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24653942, Length=516, Percent_Identity=30.6201550387597, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24653944, Length=516, Percent_Identity=30.6201550387597, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI20130025, Length=516, Percent_Identity=30.6201550387597, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24586295, Length=516, Percent_Identity=27.7131782945736, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI19921278, Length=383, Percent_Identity=24.5430809399478, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 59730; Mature: 59730

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVHRKEARMSSFRPFPSPSSATPMPGDRAASGDGRSYDLLIIGGGVNGCGIARDAAGRG
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
ARVLLVEQDDLAGHTSSASTKLIHGGLRYLEYYEFRLVREALMEREVLLRIAPHIIWPMR
EEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLPHSKLARPVWELRAGLFLYDHLALTMTLPRTRSVTFADHPSGAVLKPEFTRGFIYSD
HHCCCHHHHHHHHHHHHCHHEEEEEEEEEECCCCCEEEEECCCCCCEECCCCCCCEEECC
GWVQDARLVVLNAMDAAAHGAEIRTRTRFVSATRGRESWEATIADQETGRTGTVRARALV
CCCCCCEEEEEEEHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEEEE
NATGPWVASVLHGTLGVGGNKQVRLVKGSHIVVPRLFEGSQAYILQNPDRRIIFVIPYES
ECCCHHHHHHHHHHHCCCCCCEEEEEECCEEEEEEEECCCEEEEEECCCCEEEEEEECCC
RYTLIGTTDIPWDADPGKVAISPDEITYLCDSVNRYFRKPVQPSDVVWSYAGVRPLFDDR
CEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCHHCC
ASSASAVTRDYVLDVDTEGGAPVLSIFGGKITTYRRLAEHAIERLAPHVRSLRAVPWTGL
CCCHHHEEEEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
HALPGGEFVGRNFLGMLAQLRARAPWLDEHNAWRLMRNYGTRAFDIAAGDAAAMGQDFGS
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHCC
GLYAREVDYLIDREWARSAEDILWRRSKLGLLFSAGQVAELESYIAHRGKPVESQVADVA
CCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCHHHHHCCC
>Mature Secondary Structure
MNVHRKEARMSSFRPFPSPSSATPMPGDRAASGDGRSYDLLIIGGGVNGCGIARDAAGRG
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
ARVLLVEQDDLAGHTSSASTKLIHGGLRYLEYYEFRLVREALMEREVLLRIAPHIIWPMR
EEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLPHSKLARPVWELRAGLFLYDHLALTMTLPRTRSVTFADHPSGAVLKPEFTRGFIYSD
HHCCCHHHHHHHHHHHHCHHEEEEEEEEEECCCCCEEEEECCCCCCEECCCCCCCEEECC
GWVQDARLVVLNAMDAAAHGAEIRTRTRFVSATRGRESWEATIADQETGRTGTVRARALV
CCCCCCEEEEEEEHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEEEE
NATGPWVASVLHGTLGVGGNKQVRLVKGSHIVVPRLFEGSQAYILQNPDRRIIFVIPYES
ECCCHHHHHHHHHHHCCCCCCEEEEEECCEEEEEEEECCCEEEEEECCCCEEEEEEECCC
RYTLIGTTDIPWDADPGKVAISPDEITYLCDSVNRYFRKPVQPSDVVWSYAGVRPLFDDR
CEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCHHCC
ASSASAVTRDYVLDVDTEGGAPVLSIFGGKITTYRRLAEHAIERLAPHVRSLRAVPWTGL
CCCHHHEEEEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
HALPGGEFVGRNFLGMLAQLRARAPWLDEHNAWRLMRNYGTRAFDIAAGDAAAMGQDFGS
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHCC
GLYAREVDYLIDREWARSAEDILWRRSKLGLLFSAGQVAELESYIAHRGKPVESQVADVA
CCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]