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The map label for this gene is gsiC [H]

Identifier: 162146079

GI number: 162146079

Start: 257724

End: 258695

Strand: Direct

Name: gsiC [H]

Synonym: GDI_0248

Alternate gene names: 162146079

Gene position: 257724-258695 (Clockwise)

Preceding gene: 162146078

Following gene: 162146080

Centisome position: 6.53

GC content: 70.58

Gene sequence:

>972_bases
ATGGCGTGGTCCGGCCTGGTGGGCGGGGGCATGGCGGCGCGCCTGGCCGGCCGCGTCGGCCACGCGCTGCTGGTGCTGTG
GGGCGCGTTCACGCTCACCTTCATCCTGCTGCAGGTGCTGCCGGGCGATGCCGTCATGATCCGCTTCATGGACCCCGAAC
TCGGCCTGTCGCCCGCGCAGATCGACGCGATCCGCCTATCCTACGGCGTCGGAACGTCGCCGCTGGCGCAATATGTCCAC
ACGCTGGGGCAGATGCTGCGCGGAAATTTCGGCTATTCGGTGCAGCTTGGCGTGCCGGTCGCGTCCCTGCTGGAAAACGC
GCTGCCGGTCACGCTCCGCCTGGCCGTCTGCGGCTTCGTCGCGGCGGTGCTGTGGACCTTCGCCGTCGCCGTGGCCGCCA
ACCTGCTGCCCTGGGCGTGGATGCGCCGGCTGGCCCGGGCCGTGCCCGGCCTGTGGGGCGCGATGCCGCTGTACTGGTCG
GGTATCTTGGTCATCCAGGTCGTGTCGTTCCGCCTGCACCTGATCCCGGTGATCGGCGTGGGACCGTGGAAGGGGATGAT
CCTGCCCGCCCTGGCCGTCAGCCTGCCGATCGCGGCGCCGCTGGCGCAGATCCTGCTGCGGCACATCGACGAGGCCGGGG
CGCTGCCGTTCGCCACCGTCGCCCGCGCCAAGGGGGCCAGCCTGGCCTGGGTGTTCTGGCGGCACATCGTTCCCAACGCG
ATCCTGCCCTTCCTGACGATGGGCGGCCTCGTCTTCGGCGAACTGCTGGCCGGCGCGGTGGTGACCGAGACGATCTTCGG
GCTGGACGGCATCGGCCAGCTGACCCGCCAGGCCGTCGCCGGGCAGGATCTCGCGGTCCTGCAGGCGGTGGTCATGATCT
CGGCGGCGGCCTATGTCAGCATCAACCTGGTCGTGGACCTGCTGTATCCGGTGTTGAACCCGACCCTGCGCCATCGGACC
CGCGCGCCATGA

Upstream 100 bases:

>100_bases
ATGCCGGGGCGCCCGGCGTCCACGGCGTCGGCTTCGAGGCCGTGGGCCGCCCCAGCTTCTACGGCATATGGCTGGACCGG
CGATGACGCGCGTCCTGCCG

Downstream 100 bases:

>100_bases
GGGTGCCCGCGCGACCCGGGGCCGCGCTGGCGGCGTCCTGGCTGCTGCTGGGCCTGCTGCTGGCCATGGTGGCCGACCCG
GCCCTGTTCACCCGCTACAG

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MAWSGLVGGGMAARLAGRVGHALLVLWGAFTLTFILLQVLPGDAVMIRFMDPELGLSPAQIDAIRLSYGVGTSPLAQYVH
TLGQMLRGNFGYSVQLGVPVASLLENALPVTLRLAVCGFVAAVLWTFAVAVAANLLPWAWMRRLARAVPGLWGAMPLYWS
GILVIQVVSFRLHLIPVIGVGPWKGMILPALAVSLPIAAPLAQILLRHIDEAGALPFATVARAKGASLAWVFWRHIVPNA
ILPFLTMGGLVFGELLAGAVVTETIFGLDGIGQLTRQAVAGQDLAVLQAVVMISAAAYVSINLVVDLLYPVLNPTLRHRT
RAP

Sequences:

>Translated_323_residues
MAWSGLVGGGMAARLAGRVGHALLVLWGAFTLTFILLQVLPGDAVMIRFMDPELGLSPAQIDAIRLSYGVGTSPLAQYVH
TLGQMLRGNFGYSVQLGVPVASLLENALPVTLRLAVCGFVAAVLWTFAVAVAANLLPWAWMRRLARAVPGLWGAMPLYWS
GILVIQVVSFRLHLIPVIGVGPWKGMILPALAVSLPIAAPLAQILLRHIDEAGALPFATVARAKGASLAWVFWRHIVPNA
ILPFLTMGGLVFGELLAGAVVTETIFGLDGIGQLTRQAVAGQDLAVLQAVVMISAAAYVSINLVVDLLYPVLNPTLRHRT
RAP
>Mature_322_residues
AWSGLVGGGMAARLAGRVGHALLVLWGAFTLTFILLQVLPGDAVMIRFMDPELGLSPAQIDAIRLSYGVGTSPLAQYVHT
LGQMLRGNFGYSVQLGVPVASLLENALPVTLRLAVCGFVAAVLWTFAVAVAANLLPWAWMRRLARAVPGLWGAMPLYWSG
ILVIQVVSFRLHLIPVIGVGPWKGMILPALAVSLPIAAPLAQILLRHIDEAGALPFATVARAKGASLAWVFWRHIVPNAI
LPFLTMGGLVFGELLAGAVVTETIFGLDGIGQLTRQAVAGQDLAVLQAVVMISAAAYVSINLVVDLLYPVLNPTLRHRTR
AP

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=289, Percent_Identity=32.5259515570934, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789965, Length=334, Percent_Identity=30.2395209580838, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789888, Length=301, Percent_Identity=28.5714285714286, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1787497, Length=307, Percent_Identity=28.9902280130293, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787550, Length=291, Percent_Identity=24.7422680412371, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787761, Length=306, Percent_Identity=26.1437908496732, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788504, Length=366, Percent_Identity=22.4043715846995, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34307; Mature: 34175

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWSGLVGGGMAARLAGRVGHALLVLWGAFTLTFILLQVLPGDAVMIRFMDPELGLSPAQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHH
IDAIRLSYGVGTSPLAQYVHTLGQMLRGNFGYSVQLGVPVASLLENALPVTLRLAVCGFV
HHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHCCCCHHHHHHHHHHH
AAVLWTFAVAVAANLLPWAWMRRLARAVPGLWGAMPLYWSGILVIQVVSFRLHLIPVIGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHEEEEC
GPWKGMILPALAVSLPIAAPLAQILLRHIDEAGALPFATVARAKGASLAWVFWRHIVPNA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
ILPFLTMGGLVFGELLAGAVVTETIFGLDGIGQLTRQAVAGQDLAVLQAVVMISAAAYVS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
INLVVDLLYPVLNPTLRHRTRAP
HHHHHHHHHHHHCHHHHHCCCCC
>Mature Secondary Structure 
AWSGLVGGGMAARLAGRVGHALLVLWGAFTLTFILLQVLPGDAVMIRFMDPELGLSPAQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHH
IDAIRLSYGVGTSPLAQYVHTLGQMLRGNFGYSVQLGVPVASLLENALPVTLRLAVCGFV
HHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHCCCCHHHHHHHHHHH
AAVLWTFAVAVAANLLPWAWMRRLARAVPGLWGAMPLYWSGILVIQVVSFRLHLIPVIGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHEEEEC
GPWKGMILPALAVSLPIAAPLAQILLRHIDEAGALPFATVARAKGASLAWVFWRHIVPNA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
ILPFLTMGGLVFGELLAGAVVTETIFGLDGIGQLTRQAVAGQDLAVLQAVVMISAAAYVS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
INLVVDLLYPVLNPTLRHRTRAP
HHHHHHHHHHHHCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]