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The map label for this gene is cmpR [H]

Identifier: 162146040

GI number: 162146040

Start: 224818

End: 225723

Strand: Direct

Name: cmpR [H]

Synonym: GDI_0208

Alternate gene names: 162146040

Gene position: 224818-225723 (Clockwise)

Preceding gene: 162146031

Following gene: 162146041

Centisome position: 5.7

GC content: 66.23

Gene sequence:

>906_bases
ATGATCTCGGAACTCCGCACGTTTTCCGCAGCCGCCCGGCTGGGAAGTTTTGCCGCCGCCGCGGAGCGCGTCGGGCTGAC
GCAATCCGCCGTCAGCGCGCAGATCAGGCGGCTGGAGCAGGAACTGGGCCATGCCCTGTTCGAGCGCACCGGGCGATCGG
TGACCCTCAGTGCGGCCGGGCACCTGTCCCTTGGCCATGCCGAGAACATTCTCGCCCTGTTCGACAAGATGCGGGACCCC
GCCGCCGATATCGTCGTGCATGGACGGCTGCGTGTCGGGGCCATTTCCACCACCCATACGACGATTCTGGCCCCGGCGGT
GGCCAGTCTCAGGGTGAATTATCCCGCGCTTACCCTTCATATCGTGCCGGGCGTGTCGATGGGGCTGATGGATCGCCTGG
ATGCCGGCGAGCTCGATGCCGTCATCATCGTGCGGCCGCCTTTCGGGCTGATGCCGCATCTGGGCTGGCATCCGCTGGTC
AGGCAGCATTTTGTACTGGTCGTTCCGGCGCACCTGCCGCCGGACGACTGGCGGCAGATCATCATCAGCCAGCCCTTCAT
CCGATACGACCGCCGGTCGTTCGGCGGCCGGACCGTCGATCGCTTCCTGCAGGCGCAGGGCATCGTACCGAACACGGCGA
TCGAGACGGAGGAAGTCCATGCCATCCTGCAGATGGTCGCCAGTGACATGGGCGTTGCCATCGTTCCGTACATCCTGGCT
GTGCGCGCCATGCCGAATATCCGTGTGGTCCCGCTGGGGGAACACACGATCCTGCGCGAGATCGGGGTGCTGACGATGCT
GAGCTGGACCTCTCCCGCCCTGGACGCCCTGATCGCCCATCTGGTGCAGGCCTGCCCGGGGGACGAGCTTCCGTCCGACG
CACGGGCCGGGGAGCAGGCTCCATGA

Upstream 100 bases:

>100_bases
CTCCTTGACCCTCTCTTTGTATAAAATGTAGAACGAAACTGAGAGACAAAAATATCGCATTATTATTGATGTCAGAGACA
AAATAATTGATGGTTGTCCC

Downstream 100 bases:

>100_bases
CCGTCATGCCACCCGCGCTGGACGACGCACGCGCGTTATTCGCCCGTCTGCACACGATCGGCTTCGACGGGCTGGGAATG
ACCCGTGCGTCGTACGGCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MISELRTFSAAARLGSFAAAAERVGLTQSAVSAQIRRLEQELGHALFERTGRSVTLSAAGHLSLGHAENILALFDKMRDP
AADIVVHGRLRVGAISTTHTTILAPAVASLRVNYPALTLHIVPGVSMGLMDRLDAGELDAVIIVRPPFGLMPHLGWHPLV
RQHFVLVVPAHLPPDDWRQIIISQPFIRYDRRSFGGRTVDRFLQAQGIVPNTAIETEEVHAILQMVASDMGVAIVPYILA
VRAMPNIRVVPLGEHTILREIGVLTMLSWTSPALDALIAHLVQACPGDELPSDARAGEQAP

Sequences:

>Translated_301_residues
MISELRTFSAAARLGSFAAAAERVGLTQSAVSAQIRRLEQELGHALFERTGRSVTLSAAGHLSLGHAENILALFDKMRDP
AADIVVHGRLRVGAISTTHTTILAPAVASLRVNYPALTLHIVPGVSMGLMDRLDAGELDAVIIVRPPFGLMPHLGWHPLV
RQHFVLVVPAHLPPDDWRQIIISQPFIRYDRRSFGGRTVDRFLQAQGIVPNTAIETEEVHAILQMVASDMGVAIVPYILA
VRAMPNIRVVPLGEHTILREIGVLTMLSWTSPALDALIAHLVQACPGDELPSDARAGEQAP
>Mature_301_residues
MISELRTFSAAARLGSFAAAAERVGLTQSAVSAQIRRLEQELGHALFERTGRSVTLSAAGHLSLGHAENILALFDKMRDP
AADIVVHGRLRVGAISTTHTTILAPAVASLRVNYPALTLHIVPGVSMGLMDRLDAGELDAVIIVRPPFGLMPHLGWHPLV
RQHFVLVVPAHLPPDDWRQIIISQPFIRYDRRSFGGRTVDRFLQAQGIVPNTAIETEEVHAILQMVASDMGVAIVPYILA
VRAMPNIRVVPLGEHTILREIGVLTMLSWTSPALDALIAHLVQACPGDELPSDARAGEQAP

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787806, Length=303, Percent_Identity=26.4026402640264, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI157672245, Length=295, Percent_Identity=27.4576271186441, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790262, Length=246, Percent_Identity=28.0487804878049, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI145693105, Length=301, Percent_Identity=25.5813953488372, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787879, Length=312, Percent_Identity=27.2435897435897, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788887, Length=239, Percent_Identity=25.9414225941423, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786713, Length=132, Percent_Identity=36.3636363636364, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788626, Length=143, Percent_Identity=37.0629370629371, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788748, Length=241, Percent_Identity=26.9709543568465, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790399, Length=144, Percent_Identity=31.9444444444444, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994962, Length=146, Percent_Identity=32.1917808219178, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=176, Percent_Identity=25.5681818181818, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789440, Length=109, Percent_Identity=33.9449541284404, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788297, Length=238, Percent_Identity=26.4705882352941, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789639, Length=126, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1786401, Length=158, Percent_Identity=31.0126582278481, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32584; Mature: 32584

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISELRTFSAAARLGSFAAAAERVGLTQSAVSAQIRRLEQELGHALFERTGRSVTLSAAG
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
HLSLGHAENILALFDKMRDPAADIVVHGRLRVGAISTTHTTILAPAVASLRVNYPALTLH
CEECCCHHHHHHHHHHHCCCHHHEEEECCEEEEEECCCHHHHHHHHHHHHEECCCEEEEE
IVPGVSMGLMDRLDAGELDAVIIVRPPFGLMPHLGWHPLVRQHFVLVVPAHLPPDDWRQI
ECCCCCHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHCCEEEEEECCCCCHHHHHH
IISQPFIRYDRRSFGGRTVDRFLQAQGIVPNTAIETEEVHAILQMVASDMGVAIVPYILA
HHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
VRAMPNIRVVPLGEHTILREIGVLTMLSWTSPALDALIAHLVQACPGDELPSDARAGEQA
HHCCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHCCCCCC
P
C
>Mature Secondary Structure
MISELRTFSAAARLGSFAAAAERVGLTQSAVSAQIRRLEQELGHALFERTGRSVTLSAAG
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
HLSLGHAENILALFDKMRDPAADIVVHGRLRVGAISTTHTTILAPAVASLRVNYPALTLH
CEECCCHHHHHHHHHHHCCCHHHEEEECCEEEEEECCCHHHHHHHHHHHHEECCCEEEEE
IVPGVSMGLMDRLDAGELDAVIIVRPPFGLMPHLGWHPLVRQHFVLVVPAHLPPDDWRQI
ECCCCCHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHCCEEEEEECCCCCHHHHHH
IISQPFIRYDRRSFGGRTVDRFLQAQGIVPNTAIETEEVHAILQMVASDMGVAIVPYILA
HHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
VRAMPNIRVVPLGEHTILREIGVLTMLSWTSPALDALIAHLVQACPGDELPSDARAGEQA
HHCCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]