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The map label for this gene is ttuB [H]

Identifier: 162146021

GI number: 162146021

Start: 202257

End: 203603

Strand: Direct

Name: ttuB [H]

Synonym: GDI_0189

Alternate gene names: 162146021

Gene position: 202257-203603 (Clockwise)

Preceding gene: 162146020

Following gene: 162146022

Centisome position: 5.13

GC content: 65.11

Gene sequence:

>1347_bases
TTGACCGACCATGCCACAGGGGCAAGTGACGCGATCTCCGTGACCGAGCAGGCGGTATTCCGGGCGGCAGCCTGGCGCAT
CATTCCGCTGCTCGTCGTCTGCTACATGTTTTCCTATCTCGATCGGATCAATCTCAGTTTCGCCCGCGTTCCGATGGAAA
ACAGCCTTCATTTTTCCGACGCAACGTTCGGGCTGGGGGCGGGCCTGTTCTTCATCGGCTATATTGCCTTTCAGGTGCCC
TCGTCCCTGTTGCTGGCCCGTTTCGGGGTCAGGCGCACCATCGCGGCCATCATGATAGGCTGGAGCCTGATCTCGTTCCT
GTTCACGATCGTGGGGACCGACTGGCAGTTCTGCCTGCTGCGCGTGTCGCTGGGCGTGGCGGAGGCCGGGTTCTACCCGG
CCGTGCTCTATTACCTGGCGATATGGTTCTCGCGGCAGATGATCGCGCGGGTCACGGCGGCTTTCCTGATCGCCATTCCG
GCTTCCGGCGCCATCGGCGGTCCGGTTTCCGTCGCCATCCTGGCGCATTTTGATGGCGTACTCTCCATTCCCGGGTGGAA
ATGGATGTTCCTCCTGGAAGCCGTGCCCCCCCTTCTGCTGGGCCTGGTGGTATGGCGGCGTCTGGATGACGGTCCGGAAG
ACGCACGATGGCTCGGCGCGGCGGAGCGGCGGATCGTCCTTGCACGCGTGCATGCGGGATGGGGGGCTGCCGGCGCGGCG
TCGGCACCGGTCGGCAGGGCGCGACCCTTCGCCGCGTTGTCGCGCCCGATCGTCCGGTTGCTGATCCTGATCTGCTTCTG
CCAGGCGGTGTGCAATTACGGCATTGTCTTCTGGATCCCTACCTTCGTCGCGCAGGTGCTTGCGGCATCGTCCGCGACTA
TCGGCCTGTACATGATTATTCCCTTCGCGACGGCAATGGTGGCGATGACCCTGAATGCGCGCAGTTCCGACCGGCATCAG
GAGCGACGCTGGCATATGGCGGCCCCGTTCCTGATCGTGTCGGTCACGCTTGTGCTGGCTTTCCTGTGCCAGGGGAGCGG
CATGCTGGCCCTGCTGCTTCTGACGGCCGCGCTGGCGGCCGCGCTGTGCGTGACGGGCATGATCTTCACCATTCCCACCC
TGGTGCTGGGTCAGGAGGTGCTGGCGACCGGGCTGGCGTGGATCAACAGTCTCGGAGCGCTCGGGGGGCTGGTCGGTCCG
TATGGGATCGGTTGGCTGCGCGTCCATACCGGCCAGCCGCTGGCGGGTCTGTTTCTGGTGGCGTTCTGTGCGCTCGTCGG
GGCGATTGCCACATTGTGCCTGCCGCGACGGGCAACGGATGCGGCCCGGGTCGCGACGCCGGCGTGA

Upstream 100 bases:

>100_bases
GGTATCGTTCCCGCTTCCATATCGTTTCGCACATAAAATAAGATCGGGGGCGTATTTCCGCGCCCCCGCCGGGGGTGGGC
TACAGGAGAAGGATCAGCTG

Downstream 100 bases:

>100_bases
CAGCGGCAGGCGGGAGGCCGCGGACCCTGCGCTGATGAATCTGCGCCGCGAAATCGGACGCGGCAATGCCGGATGGGTGC
CGTTGAGCGGTTATAATATA

Product: MFS permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MTDHATGASDAISVTEQAVFRAAAWRIIPLLVVCYMFSYLDRINLSFARVPMENSLHFSDATFGLGAGLFFIGYIAFQVP
SSLLLARFGVRRTIAAIMIGWSLISFLFTIVGTDWQFCLLRVSLGVAEAGFYPAVLYYLAIWFSRQMIARVTAAFLIAIP
ASGAIGGPVSVAILAHFDGVLSIPGWKWMFLLEAVPPLLLGLVVWRRLDDGPEDARWLGAAERRIVLARVHAGWGAAGAA
SAPVGRARPFAALSRPIVRLLILICFCQAVCNYGIVFWIPTFVAQVLAASSATIGLYMIIPFATAMVAMTLNARSSDRHQ
ERRWHMAAPFLIVSVTLVLAFLCQGSGMLALLLLTAALAAALCVTGMIFTIPTLVLGQEVLATGLAWINSLGALGGLVGP
YGIGWLRVHTGQPLAGLFLVAFCALVGAIATLCLPRRATDAARVATPA

Sequences:

>Translated_448_residues
MTDHATGASDAISVTEQAVFRAAAWRIIPLLVVCYMFSYLDRINLSFARVPMENSLHFSDATFGLGAGLFFIGYIAFQVP
SSLLLARFGVRRTIAAIMIGWSLISFLFTIVGTDWQFCLLRVSLGVAEAGFYPAVLYYLAIWFSRQMIARVTAAFLIAIP
ASGAIGGPVSVAILAHFDGVLSIPGWKWMFLLEAVPPLLLGLVVWRRLDDGPEDARWLGAAERRIVLARVHAGWGAAGAA
SAPVGRARPFAALSRPIVRLLILICFCQAVCNYGIVFWIPTFVAQVLAASSATIGLYMIIPFATAMVAMTLNARSSDRHQ
ERRWHMAAPFLIVSVTLVLAFLCQGSGMLALLLLTAALAAALCVTGMIFTIPTLVLGQEVLATGLAWINSLGALGGLVGP
YGIGWLRVHTGQPLAGLFLVAFCALVGAIATLCLPRRATDAARVATPA
>Mature_447_residues
TDHATGASDAISVTEQAVFRAAAWRIIPLLVVCYMFSYLDRINLSFARVPMENSLHFSDATFGLGAGLFFIGYIAFQVPS
SLLLARFGVRRTIAAIMIGWSLISFLFTIVGTDWQFCLLRVSLGVAEAGFYPAVLYYLAIWFSRQMIARVTAAFLIAIPA
SGAIGGPVSVAILAHFDGVLSIPGWKWMFLLEAVPPLLLGLVVWRRLDDGPEDARWLGAAERRIVLARVHAGWGAAGAAS
APVGRARPFAALSRPIVRLLILICFCQAVCNYGIVFWIPTFVAQVLAASSATIGLYMIIPFATAMVAMTLNARSSDRHQE
RRWHMAAPFLIVSVTLVLAFLCQGSGMLALLLLTAALAAALCVTGMIFTIPTLVLGQEVLATGLAWINSLGALGGLVGPY
GIGWLRVHTGQPLAGLFLVAFCALVGAIATLCLPRRATDAARVATPA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=423, Percent_Identity=30.2600472813239, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI2367379, Length=348, Percent_Identity=25.2873563218391, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789515, Length=446, Percent_Identity=23.9910313901345, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=238, Percent_Identity=25.6302521008403, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6319250, Length=294, Percent_Identity=21.0884353741497, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47969; Mature: 47837

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHATGASDAISVTEQAVFRAAAWRIIPLLVVCYMFSYLDRINLSFARVPMENSLHFSD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCC
ATFGLGAGLFFIGYIAFQVPSSLLLARFGVRRTIAAIMIGWSLISFLFTIVGTDWQFCLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RVSLGVAEAGFYPAVLYYLAIWFSRQMIARVTAAFLIAIPASGAIGGPVSVAILAHFDGV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
LSIPGWKWMFLLEAVPPLLLGLVVWRRLDDGPEDARWLGAAERRIVLARVHAGWGAAGAA
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEEEEECCCCCCCCC
SAPVGRARPFAALSRPIVRLLILICFCQAVCNYGIVFWIPTFVAQVLAASSATIGLYMII
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
PFATAMVAMTLNARSSDRHQERRWHMAAPFLIVSVTLVLAFLCQGSGMLALLLLTAALAA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ALCVTGMIFTIPTLVLGQEVLATGLAWINSLGALGGLVGPYGIGWLRVHTGQPLAGLFLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHH
AFCALVGAIATLCLPRRATDAARVATPA
HHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDHATGASDAISVTEQAVFRAAAWRIIPLLVVCYMFSYLDRINLSFARVPMENSLHFSD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCC
ATFGLGAGLFFIGYIAFQVPSSLLLARFGVRRTIAAIMIGWSLISFLFTIVGTDWQFCLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RVSLGVAEAGFYPAVLYYLAIWFSRQMIARVTAAFLIAIPASGAIGGPVSVAILAHFDGV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
LSIPGWKWMFLLEAVPPLLLGLVVWRRLDDGPEDARWLGAAERRIVLARVHAGWGAAGAA
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEEEEECCCCCCCCC
SAPVGRARPFAALSRPIVRLLILICFCQAVCNYGIVFWIPTFVAQVLAASSATIGLYMII
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
PFATAMVAMTLNARSSDRHQERRWHMAAPFLIVSVTLVLAFLCQGSGMLALLLLTAALAA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ALCVTGMIFTIPTLVLGQEVLATGLAWINSLGALGGLVGPYGIGWLRVHTGQPLAGLFLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHH
AFCALVGAIATLCLPRRATDAARVATPA
HHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]