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The map label for this gene is panC [H]

Identifier: 162146013

GI number: 162146013

Start: 194990

End: 195979

Strand: Direct

Name: panC [H]

Synonym: GDI_0181

Alternate gene names: 162146013

Gene position: 194990-195979 (Clockwise)

Preceding gene: 162146011

Following gene: 162146018

Centisome position: 4.94

GC content: 70.1

Gene sequence:

>990_bases
TTGCCGGGGAAACGGGCCGATATAACCGGTCGTAACCCGTCAGGTCACAGGAAGCGGCAGGACAGAATGCTGAAGACCCT
TACGCCGGAACCGATGCGCATCCTCCATACCGTCGCCGACCTGCGGCACGTCGTGCGCGCCTGGAAGCAGGACGGGCTGA
CGGTCGGGCTGGTGCCCACGATGGGCGCGCTGCATGACGGGCACCTCAGCCTGGTGCGGGCGGCCCAGCAGGAAATGGAC
CGGGTGATCGTCTCGATCTTCGTCAACCCCACGCAATTCGACAATCCGGCCGACCTGGACAGCTACCCCCAGACCCTGGA
CGAGGATTCGCGCCTGCTGGCCGACGCCGGCACGCATATCCTCTACGCCCCCACGGTGGCCGAGATGTATCCGCCCGGCT
TTTCGACCACGATCTCGGTGGCCGGCGTATCCGAAGGGCTGTGCGGCGCCCACCGTCCCGGCCATTTCGACGGGGTGGCC
ACGGTGGTGTGCAAGCTGTTCCTGCAAAGCCAGGCCGACGCCGCCTTTTTCGGCGAGAAGGATTTCCAGCAGGTCCATGT
CGTGCGCCGCATGGCCGCCGACCTCGACATCCCGATCCGCCTGGTGGCCTGCCCGACCCGGCGCGAGGATGACGGGCTGG
CCATGTCGTCGCGCAATCGCCGCCTGACCGCCCCCGGCGAACGCGATCGCGCCCGCGCCCTGCCGCGGGCCCTGGGCGAC
GCCGCGCGGGACATCGCCGCCGGCCGTCCCGTGGGACCGGTGCTGGCGGCGACGCGGACGCGCCTGCTGGATGCCGGCTT
CGCCGAAATCGAGTATCTGGAATTGCGGCGCGATTCCGACCTGGCCCCCATGGCGCAGCGCGACGACCAGCCGGCGCGCC
TGCTGGTGGCCGGCCGGCTGGGCACGGTCCGCCTGATCGACAACGTGCCGGTAGCTGGGGAAGAAGAGCCGGGCCCGGCC
CGGGCCGGCAAGGGGTTGGGGACCCCTTGA

Upstream 100 bases:

>100_bases
TCTGGAACAACGATGCCTCCCGCCTGGACAGGCGGCGTTCATAGCAGGAAATCCGCCCCGCGCGGAAGATCCGGCGTCCC
ATACGGGGCAGGGGCTTTCC

Downstream 100 bases:

>100_bases
CCCCAATTCGTCTTCCTACACGTCCAGCGGGCGGGCTTCGTCCGGCAGCATGATGGGAATCCCGTCGCGGATCGGGAAGG
CCAGGCCGGCCTGGCGGCTG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPGKRADITGRNPSGHRKRQDRMLKTLTPEPMRILHTVADLRHVVRAWKQDGLTVGLVPTMGALHDGHLSLVRAAQQEMD
RVIVSIFVNPTQFDNPADLDSYPQTLDEDSRLLADAGTHILYAPTVAEMYPPGFSTTISVAGVSEGLCGAHRPGHFDGVA
TVVCKLFLQSQADAAFFGEKDFQQVHVVRRMAADLDIPIRLVACPTRREDDGLAMSSRNRRLTAPGERDRARALPRALGD
AARDIAAGRPVGPVLAATRTRLLDAGFAEIEYLELRRDSDLAPMAQRDDQPARLLVAGRLGTVRLIDNVPVAGEEEPGPA
RAGKGLGTP

Sequences:

>Translated_329_residues
MPGKRADITGRNPSGHRKRQDRMLKTLTPEPMRILHTVADLRHVVRAWKQDGLTVGLVPTMGALHDGHLSLVRAAQQEMD
RVIVSIFVNPTQFDNPADLDSYPQTLDEDSRLLADAGTHILYAPTVAEMYPPGFSTTISVAGVSEGLCGAHRPGHFDGVA
TVVCKLFLQSQADAAFFGEKDFQQVHVVRRMAADLDIPIRLVACPTRREDDGLAMSSRNRRLTAPGERDRARALPRALGD
AARDIAAGRPVGPVLAATRTRLLDAGFAEIEYLELRRDSDLAPMAQRDDQPARLLVAGRLGTVRLIDNVPVAGEEEPGPA
RAGKGLGTP
>Mature_328_residues
PGKRADITGRNPSGHRKRQDRMLKTLTPEPMRILHTVADLRHVVRAWKQDGLTVGLVPTMGALHDGHLSLVRAAQQEMDR
VIVSIFVNPTQFDNPADLDSYPQTLDEDSRLLADAGTHILYAPTVAEMYPPGFSTTISVAGVSEGLCGAHRPGHFDGVAT
VVCKLFLQSQADAAFFGEKDFQQVHVVRRMAADLDIPIRLVACPTRREDDGLAMSSRNRRLTAPGERDRARALPRALGDA
ARDIAAGRPVGPVLAATRTRLLDAGFAEIEYLELRRDSDLAPMAQRDDQPARLLVAGRLGTVRLIDNVPVAGEEEPGPAR
AGKGLGTP

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=282, Percent_Identity=44.6808510638298, Blast_Score=209, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6322046, Length=316, Percent_Identity=37.3417721518987, Blast_Score=169, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 35716; Mature: 35585

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGKRADITGRNPSGHRKRQDRMLKTLTPEPMRILHTVADLRHVVRAWKQDGLTVGLVPT
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
MGALHDGHLSLVRAAQQEMDRVIVSIFVNPTQFDNPADLDSYPQTLDEDSRLLADAGTHI
CCCCCCCHHHHHHHHHHHHHHEEHHEEECCCCCCCCCCCCCCCHHHCHHHHHHHHCCCEE
LYAPTVAEMYPPGFSTTISVAGVSEGLCGAHRPGHFDGVATVVCKLFLQSQADAAFFGEK
EECCHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCH
DFQQVHVVRRMAADLDIPIRLVACPTRREDDGLAMSSRNRRLTAPGERDRARALPRALGD
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEECCCCCEECCCCCHHHHHHHHHHHHH
AARDIAAGRPVGPVLAATRTRLLDAGFAEIEYLELRRDSDLAPMAQRDDQPARLLVAGRL
HHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHCCCCCCEEEEECCC
GTVRLIDNVPVAGEEEPGPARAGKGLGTP
CEEEEECCCCCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
PGKRADITGRNPSGHRKRQDRMLKTLTPEPMRILHTVADLRHVVRAWKQDGLTVGLVPT
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
MGALHDGHLSLVRAAQQEMDRVIVSIFVNPTQFDNPADLDSYPQTLDEDSRLLADAGTHI
CCCCCCCHHHHHHHHHHHHHHEEHHEEECCCCCCCCCCCCCCCHHHCHHHHHHHHCCCEE
LYAPTVAEMYPPGFSTTISVAGVSEGLCGAHRPGHFDGVATVVCKLFLQSQADAAFFGEK
EECCHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCH
DFQQVHVVRRMAADLDIPIRLVACPTRREDDGLAMSSRNRRLTAPGERDRARALPRALGD
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEECCCCCEECCCCCHHHHHHHHHHHHH
AARDIAAGRPVGPVLAATRTRLLDAGFAEIEYLELRRDSDLAPMAQRDDQPARLLVAGRL
HHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHCCCCCCEEEEECCC
GTVRLIDNVPVAGEEEPGPARAGKGLGTP
CEEEEECCCCCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA