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The map label for this gene is serB [C]

Identifier: 162145862

GI number: 162145862

Start: 19932

End: 20828

Strand: Reverse

Name: serB [C]

Synonym: GDI_0020

Alternate gene names: 162145862

Gene position: 20828-19932 (Counterclockwise)

Preceding gene: 162145868

Following gene: 162145860

Centisome position: 0.53

GC content: 70.35

Gene sequence:

>897_bases
ATGTCGCTGTCCCATATCCTTACGCTCGTCGCCAACCGCGACGCCACGACCCTGACCGATGCCCATGTCAGCGCCGCGCG
CGACATGGTGAAGGGCGGGCCGCCCAGCATCCTGTCGCCGGGCGAGGCCGTGGACATTCCCTGCCCCGCCCCCGGTCCGG
GCATGCCGACGCTGGACACGATCCGCGCCGTGTTCGGCCCGCGCCATATCGACACCCTTCTGACGCGTTCGCGCGGGCGG
CGCAAAGGGCTTCTGATCGCGGACATGGACAGCACCATCGTCGCCAACGAAACGCTGGACGACCTGGCCGCCCATGCCGG
CATCGGCGAACGCATCGCCGCGATCACCCGCCGGTCGATGAATGGCGAGATCGATTTCGCCACCGCCCTGCGCGAGCGTG
TGGGCCTGCTGGCCGGCCTACCGGCGTCGCTGCTGGAAACCGCCTGGAAGGATGTACGGCTGAACGAGGGCGCACGCACC
CTGGTGGCCACCATGCGCGCGCGCAACGCCCGCACCGCGCTGGTCTCGGGCGGATTCACCTTCTTCACCGGGCGGGTCGC
GGCGCTGTGCGGGTTTTCCGAACACCACGCCAACACGCTGGACATCCGCGACGGGACCCTGACCGGCACGGTCGGCGAGC
CGATCCTGGGCCCGGACGCCAAGCGCGCGCATCTGCACCGCCTGGCCGAGGCCGGGCGGCTGAAGCTGGCCGCCACGCTG
GCGGTGGGCGACGGGGCGAACGACCTGGACATGCTGCGCGATGCCGGGCTGGGCATCGCCTTCCACGGCAAGCCGATCGT
GCGTACCGCGATCGGCAACCGGGTGGATCATACCACCCTGCGGACGCTGCTGTTCGCGCAGGGGTATCCGGTGGGGGCCT
TCGTTACCGGGGAATAG

Upstream 100 bases:

>100_bases
ATTTGCCCGAGCAGGTCGGCCCCGCGATCACCAGCACGGGCCGGTCCCGTGCATCCGCCGCTTGCGTCATGCGGTCATCC
CTGCCACACGCCTGTGCGCC

Downstream 100 bases:

>100_bases
GACGTTCCTTTTCCGAGGAAAAGGAAGAGATCATCCCCAGATCCGGTGACGGCTGCCCCCTGGCCCGCCGGGACGACGCA
TCCTGCGCCTCGATGAACAC

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSLSHILTLVANRDATTLTDAHVSAARDMVKGGPPSILSPGEAVDIPCPAPGPGMPTLDTIRAVFGPRHIDTLLTRSRGR
RKGLLIADMDSTIVANETLDDLAAHAGIGERIAAITRRSMNGEIDFATALRERVGLLAGLPASLLETAWKDVRLNEGART
LVATMRARNARTALVSGGFTFFTGRVAALCGFSEHHANTLDIRDGTLTGTVGEPILGPDAKRAHLHRLAEAGRLKLAATL
AVGDGANDLDMLRDAGLGIAFHGKPIVRTAIGNRVDHTTLRTLLFAQGYPVGAFVTGE

Sequences:

>Translated_298_residues
MSLSHILTLVANRDATTLTDAHVSAARDMVKGGPPSILSPGEAVDIPCPAPGPGMPTLDTIRAVFGPRHIDTLLTRSRGR
RKGLLIADMDSTIVANETLDDLAAHAGIGERIAAITRRSMNGEIDFATALRERVGLLAGLPASLLETAWKDVRLNEGART
LVATMRARNARTALVSGGFTFFTGRVAALCGFSEHHANTLDIRDGTLTGTVGEPILGPDAKRAHLHRLAEAGRLKLAATL
AVGDGANDLDMLRDAGLGIAFHGKPIVRTAIGNRVDHTTLRTLLFAQGYPVGAFVTGE
>Mature_297_residues
SLSHILTLVANRDATTLTDAHVSAARDMVKGGPPSILSPGEAVDIPCPAPGPGMPTLDTIRAVFGPRHIDTLLTRSRGRR
KGLLIADMDSTIVANETLDDLAAHAGIGERIAAITRRSMNGEIDFATALRERVGLLAGLPASLLETAWKDVRLNEGARTL
VATMRARNARTALVSGGFTFFTGRVAALCGFSEHHANTLDIRDGTLTGTVGEPILGPDAKRAHLHRLAEAGRLKLAATLA
VGDGANDLDMLRDAGLGIAFHGKPIVRTAIGNRVDHTTLRTLLFAQGYPVGAFVTGE

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=191, Percent_Identity=28.7958115183246, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790849, Length=201, Percent_Identity=41.2935323383085, Blast_Score=146, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI115534456, Length=207, Percent_Identity=29.951690821256, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534454, Length=207, Percent_Identity=29.951690821256, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534458, Length=209, Percent_Identity=29.6650717703349, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=224, Percent_Identity=34.375, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 31395; Mature: 31264

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSHILTLVANRDATTLTDAHVSAARDMVKGGPPSILSPGEAVDIPCPAPGPGMPTLDT
CCHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHH
IRAVFGPRHIDTLLTRSRGRRKGLLIADMDSTIVANETLDDLAAHAGIGERIAAITRRSM
HHHHHCHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCHHHHHHHCCCHHHHHHHHHHCC
NGEIDFATALRERVGLLAGLPASLLETAWKDVRLNEGARTLVATMRARNARTALVSGGFT
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCHH
FFTGRVAALCGFSEHHANTLDIRDGTLTGTVGEPILGPDAKRAHLHRLAEAGRLKLAATL
HHHHHHHHHHCCHHHCCCEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEE
AVGDGANDLDMLRDAGLGIAFHGKPIVRTAIGNRVDHTTLRTLLFAQGYPVGAFVTGE
EECCCCCHHHHHHHCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECC
>Mature Secondary Structure 
SLSHILTLVANRDATTLTDAHVSAARDMVKGGPPSILSPGEAVDIPCPAPGPGMPTLDT
CHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHH
IRAVFGPRHIDTLLTRSRGRRKGLLIADMDSTIVANETLDDLAAHAGIGERIAAITRRSM
HHHHHCHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCHHHHHHHCCCHHHHHHHHHHCC
NGEIDFATALRERVGLLAGLPASLLETAWKDVRLNEGARTLVATMRARNARTALVSGGFT
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCHH
FFTGRVAALCGFSEHHANTLDIRDGTLTGTVGEPILGPDAKRAHLHRLAEAGRLKLAATL
HHHHHHHHHHCCHHHCCCEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEE
AVGDGANDLDMLRDAGLGIAFHGKPIVRTAIGNRVDHTTLRTLLFAQGYPVGAFVTGE
EECCCCCHHHHHHHCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11342136; 12051918 [H]