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The map label for this gene is rppH [H]

Identifier: 161870531

GI number: 161870531

Start: 1626145

End: 1626669

Strand: Reverse

Name: rppH [H]

Synonym: NMCC_1596

Alternate gene names: 161870531

Gene position: 1626669-1626145 (Counterclockwise)

Preceding gene: 161870533

Following gene: 161870530

Centisome position: 75.54

GC content: 58.1

Gene sequence:

>525_bases
GTGTTGGACAGGGAAGGCTATCGCCCCAATGTCGGTATTATCCTGATTAACGAACGTAACGAAGTCTTTTGGGGCAAGCG
CGTGCGCGAACATTCTTGGCAGTTTCCGCAAGGCGGCATCAAGCCGGGCGAAAGCCCCGAAACCGCGATGTACCGCGAGC
TTTACGAAGAAGTCGGACTTCTGCCGCAACACGTCAAAATCGTCGGGCGGACGCGCGACTGGCTGCGTTACGACGTGCCG
AACAACTGGGTGCGCCGCGAATGGCGCGGATCTTATCGCGGGCAGAAGCAGATTTGGTATCTCCTGCGCCTGACCGGCCG
GGATTGCGATGTCAACCTGCGCGCCACCCGCCACCCCGAATTTGACGGCTGGCGTTGGCATCAATATTGGGCGCCCGTTG
ACGAAGTCATCGAGTTCAAACGCGACGTTTATTTGGGGGCGTTGAAAGAACTCTCTTCCCGCTTCCTGCGCGGTATGGAA
AGTTATGAAGACTTTGCCGCCCGCCAACCTTCCGGCAACCGGTAA

Upstream 100 bases:

>100_bases
CCGTCTGTGTTTCGACATGCTTGAACCATGCCGTCTGATTTGTCAAAACCGCCCGATTTGTGGGAAAATCGTACGATTGA
ATTTAACGGAGGGCGACACC

Downstream 100 bases:

>100_bases
AACAACGGAACGCAACGCTTTCAGGCCGTCTGAAAGCGTTGTTTTTCTTACTTTCAGATTATTCCTATGGCTAAAAACAA
CCAATACAGCGAATCCAGCA

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MLDREGYRPNVGIILINERNEVFWGKRVREHSWQFPQGGIKPGESPETAMYRELYEEVGLLPQHVKIVGRTRDWLRYDVP
NNWVRREWRGSYRGQKQIWYLLRLTGRDCDVNLRATRHPEFDGWRWHQYWAPVDEVIEFKRDVYLGALKELSSRFLRGME
SYEDFAARQPSGNR

Sequences:

>Translated_174_residues
MLDREGYRPNVGIILINERNEVFWGKRVREHSWQFPQGGIKPGESPETAMYRELYEEVGLLPQHVKIVGRTRDWLRYDVP
NNWVRREWRGSYRGQKQIWYLLRLTGRDCDVNLRATRHPEFDGWRWHQYWAPVDEVIEFKRDVYLGALKELSSRFLRGME
SYEDFAARQPSGNR
>Mature_174_residues
MLDREGYRPNVGIILINERNEVFWGKRVREHSWQFPQGGIKPGESPETAMYRELYEEVGLLPQHVKIVGRTRDWLRYDVP
NNWVRREWRGSYRGQKQIWYLLRLTGRDCDVNLRATRHPEFDGWRWHQYWAPVDEVIEFKRDVYLGALKELSSRFLRGME
SYEDFAARQPSGNR

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=161, Percent_Identity=52.1739130434783, Blast_Score=182, Evalue=9e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 20986; Mature: 20986

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDREGYRPNVGIILINERNEVFWGKRVREHSWQFPQGGIKPGESPETAMYRELYEEVGL
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
LPQHVKIVGRTRDWLRYDVPNNWVRREWRGSYRGQKQIWYLLRLTGRDCDVNLRATRHPE
CHHHHHHHCCCCHHEEECCCCHHHHHHHCCCCCCHHHEEEEEEECCCCCCEEEEECCCCC
FDGWRWHQYWAPVDEVIEFKRDVYLGALKELSSRFLRGMESYEDFAARQPSGNR
CCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLDREGYRPNVGIILINERNEVFWGKRVREHSWQFPQGGIKPGESPETAMYRELYEEVGL
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
LPQHVKIVGRTRDWLRYDVPNNWVRREWRGSYRGQKQIWYLLRLTGRDCDVNLRATRHPE
CHHHHHHHCCCCHHEEECCCCHHHHHHHCCCCCCHHHEEEEEEECCCCCCEEEEECCCCC
FDGWRWHQYWAPVDEVIEFKRDVYLGALKELSSRFLRGMESYEDFAARQPSGNR
CCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA