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The map label for this gene is sdhB [H]

Identifier: 161869864

GI number: 161869864

Start: 895460

End: 896167

Strand: Direct

Name: sdhB [H]

Synonym: NMCC_0895

Alternate gene names: 161869864

Gene position: 895460-896167 (Clockwise)

Preceding gene: 161869863

Following gene: 161869865

Centisome position: 41.58

GC content: 47.74

Gene sequence:

>708_bases
ATGGAAAAAATGAGTTTTGAAATTTACCGTTACAACCCGGATGTTGATGCCAAGCCTTATATGCAGCGTTACGAGTTGGA
ATTGGAACCGACCGACGTGAAACTTTTGGACGCTTTAGTGCGCTTGAAAGCACAAGACGATACCTTGTCTTTCCGCCGCT
CCTGCCGCGAAGGGATTTGCGGTTCTGACGGTATGAACATCAACGGCAAAAACGGCTTGGCGTGTTTGACCGATCTGCGT
GGCTTGAAACAGCCGGTTAAAATTCGTCCTCTGCCAGGTCTGCCTGTTATCCGCGACCTGATTGTGGATATGACCCAGTT
CTTCAAACAATACCATTCCGTCAAACCTTATGTTGTCAACGATAATCCGATTGATGCGGACAAAGAGCGTCTGCAAACTC
AGGAAGAGCGTAAAGAGTTGGACGGTTTGTACGAGTGTATTTTGTGCGCCTGCTGTTCGACTGCCTGCCCGTCATTTTGG
TGGAACCCTGATAAATTCGTCGGTCCGTCCGGTTTGCTGAATGCTTACCGTTTCATTGCGGACAGCCGTGATACCATCAC
TAATGAGCGTTTGGATAATCTGAACGACCCATACCGTTTGTTCCGTTGCCACACCATTATGAACTGCGTAGACGTATGTC
CTAAACACTTGAATCCGACCCGAGCCATCGGTAAGATTAAAGAGATTATGTTGAAACGGGCCGTTTAA

Upstream 100 bases:

>100_bases
CGCCTCAAAGGTCGTCTGAAATCTAACCATACCCACATTGAACTGCTTGAATTTATAATACAAAATCATTGGGCAGTTGA
TGAGAAAAGGAACACTTCTC

Downstream 100 bases:

>100_bases
GAAATGATGGTTTTTGACGATATTGCCAAACGGAAAATCCGTTTTCAAACCCGCCGGGGATTGTTGGAGTTAGATTTAAT
CTTCGGCAGGTTTATGGAAA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MEKMSFEIYRYNPDVDAKPYMQRYELELEPTDVKLLDALVRLKAQDDTLSFRRSCREGICGSDGMNINGKNGLACLTDLR
GLKQPVKIRPLPGLPVIRDLIVDMTQFFKQYHSVKPYVVNDNPIDADKERLQTQEERKELDGLYECILCACCSTACPSFW
WNPDKFVGPSGLLNAYRFIADSRDTITNERLDNLNDPYRLFRCHTIMNCVDVCPKHLNPTRAIGKIKEIMLKRAV

Sequences:

>Translated_235_residues
MEKMSFEIYRYNPDVDAKPYMQRYELELEPTDVKLLDALVRLKAQDDTLSFRRSCREGICGSDGMNINGKNGLACLTDLR
GLKQPVKIRPLPGLPVIRDLIVDMTQFFKQYHSVKPYVVNDNPIDADKERLQTQEERKELDGLYECILCACCSTACPSFW
WNPDKFVGPSGLLNAYRFIADSRDTITNERLDNLNDPYRLFRCHTIMNCVDVCPKHLNPTRAIGKIKEIMLKRAV
>Mature_235_residues
MEKMSFEIYRYNPDVDAKPYMQRYELELEPTDVKLLDALVRLKAQDDTLSFRRSCREGICGSDGMNINGKNGLACLTDLR
GLKQPVKIRPLPGLPVIRDLIVDMTQFFKQYHSVKPYVVNDNPIDADKERLQTQEERKELDGLYECILCACCSTACPSFW
WNPDKFVGPSGLLNAYRFIADSRDTITNERLDNLNDPYRLFRCHTIMNCVDVCPKHLNPTRAIGKIKEIMLKRAV

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=229, Percent_Identity=54.585152838428, Blast_Score=262, Evalue=2e-70,
Organism=Escherichia coli, GI1786943, Length=235, Percent_Identity=65.9574468085106, Blast_Score=332, Evalue=1e-92,
Organism=Escherichia coli, GI1790596, Length=233, Percent_Identity=38.6266094420601, Blast_Score=164, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17533915, Length=230, Percent_Identity=50.8695652173913, Blast_Score=260, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6322987, Length=227, Percent_Identity=51.1013215859031, Blast_Score=248, Evalue=8e-67,
Organism=Drosophila melanogaster, GI17137106, Length=231, Percent_Identity=52.8138528138528, Blast_Score=261, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24643156, Length=231, Percent_Identity=51.0822510822511, Blast_Score=253, Evalue=7e-68,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 27087; Mature: 27087

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKMSFEIYRYNPDVDAKPYMQRYELELEPTDVKLLDALVRLKAQDDTLSFRRSCREGIC
CCCCEEEEEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
GSDGMNINGKNGLACLTDLRGLKQPVKIRPLPGLPVIRDLIVDMTQFFKQYHSVKPYVVN
CCCCCCCCCCCCHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEC
DNPIDADKERLQTQEERKELDGLYECILCACCSTACPSFWWNPDKFVGPSGLLNAYRFIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
DSRDTITNERLDNLNDPYRLFRCHTIMNCVDVCPKHLNPTRAIGKIKEIMLKRAV
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKMSFEIYRYNPDVDAKPYMQRYELELEPTDVKLLDALVRLKAQDDTLSFRRSCREGIC
CCCCEEEEEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
GSDGMNINGKNGLACLTDLRGLKQPVKIRPLPGLPVIRDLIVDMTQFFKQYHSVKPYVVN
CCCCCCCCCCCCHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEC
DNPIDADKERLQTQEERKELDGLYECILCACCSTACPSFWWNPDKFVGPSGLLNAYRFIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
DSRDTITNERLDNLNDPYRLFRCHTIMNCVDVCPKHLNPTRAIGKIKEIMLKRAV
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]