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The map label for this gene is panC [H]

Identifier: 161869805

GI number: 161869805

Start: 834434

End: 835195

Strand: Direct

Name: panC [H]

Synonym: NMCC_0830

Alternate gene names: 161869805

Gene position: 834434-835195 (Clockwise)

Preceding gene: 161869804

Following gene: 161869806

Centisome position: 38.75

GC content: 54.2

Gene sequence:

>762_bases
ATGGGCAATCTGCATGAAGGGCATCTTGCGCTTGTGCGTGAGGCGAAAAAACGCGCGGACAGTGTCGTGGTCAGCATTTT
CGTCAACCGCCTGCAATTCGGTCAGGGCGAGGATTTCGACAAATATCCGCGTACTTTGCAACAGGATGCGGACAAGCTGG
AAGCCGAGGGTGTTGCCGTTGTTTTCGCGCCCGATGAGAAAGAACTCTATCCGAACGTGGAACAGCGTTACAACGTCGAA
CCGCCCAATCTGCAAAATGAGTTGTGCGGCAAGTTTCGTCCGGGACATTTCCGCGGGGTGGCAACGGTAGTGTCCAAGCT
GTTCAATATTGTCGCGCCGGATGTTGCCTGTTTCGGCAAAAAAGACTATCAGCAGCTTGCCGTGATTAAAGGTTTGACCG
AGGATTTGAATTTTGATGTTGAAATAGTGCCTGTCGATACGGGGCGCGCGGAAGACGGTTTGGCACTCTCCAGCCGCAAC
CAGTATTTGAGTGCGGCGGAACGCGACGAAGCACCGCGCCTGTACCGCGAATTAAAGGCTGTTGCCGAATCCTTGGCGCA
GGGCAGTTTGGATTATGCAGGTTTGGAAAAACGTGCCGTCCAATCCCTGACAGAATACGGCTGGGTGGTCGATTATGTCG
AAATCCGCCGCGTCGATACGCTCGAAGTGGCGCGGGCGGGAGATAAGAAACTGGTGGTCTTGGCCGCCGCCCGTCTGGGG
ACGACGCGCCTGATTGACAATTTGGAAATAAAACTCCCTTAA

Upstream 100 bases:

>100_bases
AGCCCGAAGGATAAGGATTACCGTTATGCAAATCATACATACCATTCGAGAACTGCGCGCGTGGCGTAAAAATGCGGGAA
AGGTGGCATTTGTGCCGACC

Downstream 100 bases:

>100_bases
ACCGCAAGCGTCGGGAATGCCGTCTGAAGCGGATTTGCGTTTCAGACGGCATTTATTTTTTTGAACGGGGTTTCGCAAAT
CTACAAACGATTCTGCTTGT

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MGNLHEGHLALVREAKKRADSVVVSIFVNRLQFGQGEDFDKYPRTLQQDADKLEAEGVAVVFAPDEKELYPNVEQRYNVE
PPNLQNELCGKFRPGHFRGVATVVSKLFNIVAPDVACFGKKDYQQLAVIKGLTEDLNFDVEIVPVDTGRAEDGLALSSRN
QYLSAAERDEAPRLYRELKAVAESLAQGSLDYAGLEKRAVQSLTEYGWVVDYVEIRRVDTLEVARAGDKKLVVLAAARLG
TTRLIDNLEIKLP

Sequences:

>Translated_253_residues
MGNLHEGHLALVREAKKRADSVVVSIFVNRLQFGQGEDFDKYPRTLQQDADKLEAEGVAVVFAPDEKELYPNVEQRYNVE
PPNLQNELCGKFRPGHFRGVATVVSKLFNIVAPDVACFGKKDYQQLAVIKGLTEDLNFDVEIVPVDTGRAEDGLALSSRN
QYLSAAERDEAPRLYRELKAVAESLAQGSLDYAGLEKRAVQSLTEYGWVVDYVEIRRVDTLEVARAGDKKLVVLAAARLG
TTRLIDNLEIKLP
>Mature_252_residues
GNLHEGHLALVREAKKRADSVVVSIFVNRLQFGQGEDFDKYPRTLQQDADKLEAEGVAVVFAPDEKELYPNVEQRYNVEP
PNLQNELCGKFRPGHFRGVATVVSKLFNIVAPDVACFGKKDYQQLAVIKGLTEDLNFDVEIVPVDTGRAEDGLALSSRNQ
YLSAAERDEAPRLYRELKAVAESLAQGSLDYAGLEKRAVQSLTEYGWVVDYVEIRRVDTLEVARAGDKKLVVLAAARLGT
TRLIDNLEIKLP

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=253, Percent_Identity=53.7549407114625, Blast_Score=261, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6322046, Length=277, Percent_Identity=37.5451263537906, Blast_Score=155, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 28174; Mature: 28043

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNLHEGHLALVREAKKRADSVVVSIFVNRLQFGQGEDFDKYPRTLQQDADKLEAEGVAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEE
VFAPDEKELYPNVEQRYNVEPPNLQNELCGKFRPGHFRGVATVVSKLFNIVAPDVACFGK
EECCCCHHHCCCHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCC
KDYQQLAVIKGLTEDLNFDVEIVPVDTGRAEDGLALSSRNQYLSAAERDEAPRLYRELKA
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCHHHHHHHHCCCHHHHHHHHHH
VAESLAQGSLDYAGLEKRAVQSLTEYGWVVDYVEIRRVDTLEVARAGDKKLVVLAAARLG
HHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCCCEEEEEEEHHHC
TTRLIDNLEIKLP
HHHHHCCEEEECC
>Mature Secondary Structure 
GNLHEGHLALVREAKKRADSVVVSIFVNRLQFGQGEDFDKYPRTLQQDADKLEAEGVAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEE
VFAPDEKELYPNVEQRYNVEPPNLQNELCGKFRPGHFRGVATVVSKLFNIVAPDVACFGK
EECCCCHHHCCCHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCC
KDYQQLAVIKGLTEDLNFDVEIVPVDTGRAEDGLALSSRNQYLSAAERDEAPRLYRELKA
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCHHHHHHHHCCCHHHHHHHHHH
VAESLAQGSLDYAGLEKRAVQSLTEYGWVVDYVEIRRVDTLEVARAGDKKLVVLAAARLG
HHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCCCEEEEEEEHHHC
TTRLIDNLEIKLP
HHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]