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The map label for this gene is trpB [H]

Identifier: 161869641

GI number: 161869641

Start: 665618

End: 666820

Strand: Direct

Name: trpB [H]

Synonym: NMCC_0658

Alternate gene names: 161869641

Gene position: 665618-666820 (Clockwise)

Preceding gene: 161869640

Following gene: 161869643

Centisome position: 30.91

GC content: 58.27

Gene sequence:

>1203_bases
ATGAAGAACTACCACGCGCCCGACGAGAAGGGCTTTTTCGGCGAACACGGCGGGCTTTATGTTTCCGAGACCCTGATTCC
CGCCTTGCAAGAGCTGGCGGATGCCTATAAGGCAGCGAAAAACGATCCTGAATTTTGGGCGGAGTTTCGCTGCGATTTGA
AACATTATGTCGGCAGGCCCAGCCCCGTTTACCACGCCGCGCGGTTGTCCGAGCATTTGGGCGGCGCGCAAATCTGGTTG
AAGCGCGAAGACTTGAACCACACCGGCGCGCACAAAGTCAACAACACCATCGGTCAGGCACTGTTGGCAAAACGCATGGG
TAAAAAACGCGTCATCGCCGAAACCGGCGCGGGTCAGCACGGCGTGGCGAGTGCCACCGTTGCCGCACGCTTCGGTATGA
CTTGCGACGTGTATATGGGCGCGGACGACATCCAACGCCAAATGCCCAACGTGTTCCGTATGAAATTATTGGGCGCGAAC
GTGGTCGGTGTAGAAAGCGGCAGCCGCACGCTGAAAGACGCGATGAACGAAGCCATGCGCGAATGGGTCGCCCGCGTGGA
CGACACGTTCTACATCATCGGTACCGCCGCCGGCCCCGCGCCGTATCCCGAAATGGTGCGCGATTTCCAATGCGTGATTG
GCAACGAAGCTAAAGCGCAGATGCAGGAAGCCATCGGCAGACAGCCCGACGTTGCCGTTGCCTGCGTGGGCGGCGGATCG
AACGCCATCGGTTTGTTCCACCCGTATATCGGCGAAGAAAACGTGCGCCTCGTCGGCGTGGAGGCTGGCGGTTTGGGCGT
GAACACCCCCGATCACGCCGCGCCGATTACTTCGGGCGCACCGATTGGCGTATTGCACGGTTTCCGCAGCTATCTGATGC
AGGACGAAAACGGTCAGGTTTTGGGTACGCACTCTGTTTCCGCAGGCTTGGATTACCCCGGCATCGGCCCGGAACACAGC
CATCTGCACGACATCAAGCGCGTCGAATACACTGTTGCCAAAGACGACGAAGCACTCGAAGCCTTTGACTTGCTCTGCCG
CTTCGAGGGCATCATCCCCGCGCTCGAATCCAGCCACGCCGTTGCTTGGGCGGTGAAAAATGCGCCGAAAATGGGTAAAG
ACCAAGTGATTTTGGTCAACCTCTCAGGTCGTGGCGACAAAGACATCAATACCGTCGCGAAGCTCAAAGGGATTAAACTG
TAA

Upstream 100 bases:

>100_bases
TGTGAAAAGCAGTTATAATTGCCGACAATTTCCCGTTCGGACGGCATGTTTGAAAAAACGGAAATGCCGTTTGAAAACCT
GAAGCACAAGGAAGAATCCG

Downstream 100 bases:

>100_bases
CCTCGTCCGTCTGATATAGTGGATTAACAAAAACCAGTACGGCGTTGCCTCGCCTTGCCGTACTATCTGTACTGTCTGCG
GCTTCGTCGCCTTGTCCTGA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MKNYHAPDEKGFFGEHGGLYVSETLIPALQELADAYKAAKNDPEFWAEFRCDLKHYVGRPSPVYHAARLSEHLGGAQIWL
KREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAETGAGQHGVASATVAARFGMTCDVYMGADDIQRQMPNVFRMKLLGAN
VVGVESGSRTLKDAMNEAMREWVARVDDTFYIIGTAAGPAPYPEMVRDFQCVIGNEAKAQMQEAIGRQPDVAVACVGGGS
NAIGLFHPYIGEENVRLVGVEAGGLGVNTPDHAAPITSGAPIGVLHGFRSYLMQDENGQVLGTHSVSAGLDYPGIGPEHS
HLHDIKRVEYTVAKDDEALEAFDLLCRFEGIIPALESSHAVAWAVKNAPKMGKDQVILVNLSGRGDKDINTVAKLKGIKL

Sequences:

>Translated_400_residues
MKNYHAPDEKGFFGEHGGLYVSETLIPALQELADAYKAAKNDPEFWAEFRCDLKHYVGRPSPVYHAARLSEHLGGAQIWL
KREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAETGAGQHGVASATVAARFGMTCDVYMGADDIQRQMPNVFRMKLLGAN
VVGVESGSRTLKDAMNEAMREWVARVDDTFYIIGTAAGPAPYPEMVRDFQCVIGNEAKAQMQEAIGRQPDVAVACVGGGS
NAIGLFHPYIGEENVRLVGVEAGGLGVNTPDHAAPITSGAPIGVLHGFRSYLMQDENGQVLGTHSVSAGLDYPGIGPEHS
HLHDIKRVEYTVAKDDEALEAFDLLCRFEGIIPALESSHAVAWAVKNAPKMGKDQVILVNLSGRGDKDINTVAKLKGIKL
>Mature_400_residues
MKNYHAPDEKGFFGEHGGLYVSETLIPALQELADAYKAAKNDPEFWAEFRCDLKHYVGRPSPVYHAARLSEHLGGAQIWL
KREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAETGAGQHGVASATVAARFGMTCDVYMGADDIQRQMPNVFRMKLLGAN
VVGVESGSRTLKDAMNEAMREWVARVDDTFYIIGTAAGPAPYPEMVRDFQCVIGNEAKAQMQEAIGRQPDVAVACVGGGS
NAIGLFHPYIGEENVRLVGVEAGGLGVNTPDHAAPITSGAPIGVLHGFRSYLMQDENGQVLGTHSVSAGLDYPGIGPEHS
HLHDIKRVEYTVAKDDEALEAFDLLCRFEGIIPALESSHAVAWAVKNAPKMGKDQVILVNLSGRGDKDINTVAKLKGIKL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=382, Percent_Identity=54.9738219895288, Blast_Score=429, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=55.7291666666667, Blast_Score=446, Evalue=1e-126,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43176; Mature: 43176

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYHAPDEKGFFGEHGGLYVSETLIPALQELADAYKAAKNDPEFWAEFRCDLKHYVGRP
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
SPVYHAARLSEHLGGAQIWLKREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAETGAGQH
CHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
GVASATVAARFGMTCDVYMGADDIQRQMPNVFRMKLLGANVVGVESGSRTLKDAMNEAMR
CCHHHHHHHHCCCEEEEEECCHHHHHHCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHH
EWVARVDDTFYIIGTAAGPAPYPEMVRDFQCVIGNEAKAQMQEAIGRQPDVAVACVGGGS
HHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCC
NAIGLFHPYIGEENVRLVGVEAGGLGVNTPDHAAPITSGAPIGVLHGFRSYLMQDENGQV
CCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCE
LGTHSVSAGLDYPGIGPEHSHLHDIKRVEYTVAKDDEALEAFDLLCRFEGIIPALESSHA
EEECCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCE
VAWAVKNAPKMGKDQVILVNLSGRGDKDINTVAKLKGIKL
EEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MKNYHAPDEKGFFGEHGGLYVSETLIPALQELADAYKAAKNDPEFWAEFRCDLKHYVGRP
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
SPVYHAARLSEHLGGAQIWLKREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAETGAGQH
CHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
GVASATVAARFGMTCDVYMGADDIQRQMPNVFRMKLLGANVVGVESGSRTLKDAMNEAMR
CCHHHHHHHHCCCEEEEEECCHHHHHHCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHH
EWVARVDDTFYIIGTAAGPAPYPEMVRDFQCVIGNEAKAQMQEAIGRQPDVAVACVGGGS
HHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCC
NAIGLFHPYIGEENVRLVGVEAGGLGVNTPDHAAPITSGAPIGVLHGFRSYLMQDENGQV
CCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCE
LGTHSVSAGLDYPGIGPEHSHLHDIKRVEYTVAKDDEALEAFDLLCRFEGIIPALESSHA
EEECCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCE
VAWAVKNAPKMGKDQVILVNLSGRGDKDINTVAKLKGIKL
EEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA