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The map label for this gene is 161869537

Identifier: 161869537

GI number: 161869537

Start: 573999

End: 575108

Strand: Reverse

Name: 161869537

Synonym: NMCC_0551

Alternate gene names: NA

Gene position: 575108-573999 (Counterclockwise)

Preceding gene: 161869547

Following gene: 161869536

Centisome position: 26.71

GC content: 58.02

Gene sequence:

>1110_bases
ATGTCCTTGACCCGCCTAATCTTGAAATTCTATGCACTGTTGCGCCTTTTTTTGGGCAAAAACGCCCGCACCGCATGGAT
TTCGCATCCCGCCTGCACCGGGCACGAACCCGGCGCAAACCATCCCGATTCGCCCGACCGCATCCTCTGCATCGAGCAGG
CATTGCGCCGCGCCGGTATTTGGCAGCACCTCCAAACCATAGAGGCGGAAGAAATCAGCGATACGCGCCTCGCACTTGTC
CACTCGAGCAAATATCTGAACCGTTTGGAATCTTGCCTGCCCCAAAAAGGCAAGATTTTCCGCCTGGATAACGACACTGC
AATCAGCACAGGCTCGCTGTCTGCCGCACACTTTGCCGCCGGTTCGGCAGTTCAGGCAGTCGACATGGTCATGAACCGTA
AAGCATGGCATGCCTTTTGCGCCGCCCGCCCGCCCGGACACCATGCGGGCAGCGGCAAAGCCGGCGGATTCTGCCTGCTG
AACAACGTTGCCGCCGGCGTCATGCATGCCATTGCCGAATACCGCCTGAAACGCATTGCCGTCATCGATTTCGATGTCCA
CTACGGCGACGGTACGGCAGAAATATTCAAAGACGATCCGCGCATCCTGTTTTTCAACCTGTTTGAAACCGACCTTTTCC
CCTTCCCCGAAAACAACGATATGCCCGACGGCGGCAATATGGTGCACCTGCCCTTGCCGCCGGGAACGGGCAGCCGCACA
TTCCGCGAAGCCGTCCGCAGACAGTGGCTGCCCCGGCTTGCCGCATTCAAACCCGAACTGGTGCTGCTGTCGGCAGGATT
CGACGCACACCGTCTGGACGAATCGGGCAGGCTCAACCTGCACGAGGCGGATTTTGCCTGGCTGACACACAAAATCATTC
AGACGGCATCGGGCTGCCCCGGCAAAATCGTATCCGTACTCGAAGGCGGCTACACCCTTGAACCTCTGGCACAATCTGCT
GCCGAGCATATCCGCGTGCTGGCGGGGCTGGGCAAATCCGATGCCGCAACCGCCTATCAGAAAACACTGGATCCAACAAA
AAAACGGTTTGCCAAACCGAAAACCGGACAGGTGCGCCAACCTACCCAATCCGACCGTTACGACATATAG

Upstream 100 bases:

>100_bases
GAAAATCGAGAGGGGTATATAATAACATAAGACCGTAAACAATATATCGGGTTTGCCGTCCGTACCGACCGTATACCGCA
GCCTGCCCGTCCACAAACCC

Downstream 100 bases:

>100_bases
TGGATTAACAAAAATCAGGACAAGGCGACGAAGCCGCAGACAGTACAAATAGTACGGAACCGATTCACTTGGTGCTTCAG
CACATTAGAGAATCGTTCTC

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSLTRLILKFYALLRLFLGKNARTAWISHPACTGHEPGANHPDSPDRILCIEQALRRAGIWQHLQTIEAEEISDTRLALV
HSSKYLNRLESCLPQKGKIFRLDNDTAISTGSLSAAHFAAGSAVQAVDMVMNRKAWHAFCAARPPGHHAGSGKAGGFCLL
NNVAAGVMHAIAEYRLKRIAVIDFDVHYGDGTAEIFKDDPRILFFNLFETDLFPFPENNDMPDGGNMVHLPLPPGTGSRT
FREAVRRQWLPRLAAFKPELVLLSAGFDAHRLDESGRLNLHEADFAWLTHKIIQTASGCPGKIVSVLEGGYTLEPLAQSA
AEHIRVLAGLGKSDAATAYQKTLDPTKKRFAKPKTGQVRQPTQSDRYDI

Sequences:

>Translated_369_residues
MSLTRLILKFYALLRLFLGKNARTAWISHPACTGHEPGANHPDSPDRILCIEQALRRAGIWQHLQTIEAEEISDTRLALV
HSSKYLNRLESCLPQKGKIFRLDNDTAISTGSLSAAHFAAGSAVQAVDMVMNRKAWHAFCAARPPGHHAGSGKAGGFCLL
NNVAAGVMHAIAEYRLKRIAVIDFDVHYGDGTAEIFKDDPRILFFNLFETDLFPFPENNDMPDGGNMVHLPLPPGTGSRT
FREAVRRQWLPRLAAFKPELVLLSAGFDAHRLDESGRLNLHEADFAWLTHKIIQTASGCPGKIVSVLEGGYTLEPLAQSA
AEHIRVLAGLGKSDAATAYQKTLDPTKKRFAKPKTGQVRQPTQSDRYDI
>Mature_368_residues
SLTRLILKFYALLRLFLGKNARTAWISHPACTGHEPGANHPDSPDRILCIEQALRRAGIWQHLQTIEAEEISDTRLALVH
SSKYLNRLESCLPQKGKIFRLDNDTAISTGSLSAAHFAAGSAVQAVDMVMNRKAWHAFCAARPPGHHAGSGKAGGFCLLN
NVAAGVMHAIAEYRLKRIAVIDFDVHYGDGTAEIFKDDPRILFFNLFETDLFPFPENNDMPDGGNMVHLPLPPGTGSRTF
REAVRRQWLPRLAAFKPELVLLSAGFDAHRLDESGRLNLHEADFAWLTHKIIQTASGCPGKIVSVLEGGYTLEPLAQSAA
EHIRVLAGLGKSDAATAYQKTLDPTKKRFAKPKTGQVRQPTQSDRYDI

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=338, Percent_Identity=32.2485207100592, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI13128864, Length=305, Percent_Identity=32.7868852459016, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI226529806, Length=338, Percent_Identity=29.2899408284024, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI169234807, Length=326, Percent_Identity=28.5276073619632, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI148539870, Length=326, Percent_Identity=28.5276073619632, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI153085395, Length=349, Percent_Identity=28.6532951289398, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI30795202, Length=327, Percent_Identity=28.1345565749235, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI17158039, Length=327, Percent_Identity=28.1345565749235, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI30795204, Length=327, Percent_Identity=28.1345565749235, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI62750347, Length=345, Percent_Identity=26.0869565217391, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI62750349, Length=345, Percent_Identity=26.0869565217391, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI13128860, Length=294, Percent_Identity=22.4489795918367, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI13128862, Length=270, Percent_Identity=21.8518518518519, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI293336691, Length=256, Percent_Identity=22.265625, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI217272877, Length=271, Percent_Identity=23.9852398523985, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI209862883, Length=267, Percent_Identity=25.0936329588015, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=306, Percent_Identity=32.6797385620915, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17540332, Length=306, Percent_Identity=32.3529411764706, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI193206283, Length=306, Percent_Identity=32.3529411764706, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI193209491, Length=343, Percent_Identity=31.1953352769679, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI25154020, Length=299, Percent_Identity=30.4347826086957, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25154022, Length=313, Percent_Identity=30.0319488817891, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17537347, Length=305, Percent_Identity=28.5245901639344, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17534739, Length=340, Percent_Identity=23.5294117647059, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17508561, Length=294, Percent_Identity=23.8095238095238, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561978, Length=279, Percent_Identity=24.0143369175627, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324307, Length=323, Percent_Identity=27.8637770897833, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323999, Length=360, Percent_Identity=22.7777777777778, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6325141, Length=295, Percent_Identity=25.4237288135593, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321244, Length=273, Percent_Identity=21.6117216117216, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281360899, Length=307, Percent_Identity=30.6188925081433, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24642146, Length=307, Percent_Identity=30.6188925081433, Blast_Score=147, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24642142, Length=307, Percent_Identity=30.6188925081433, Blast_Score=147, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24642144, Length=307, Percent_Identity=30.6188925081433, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24641720, Length=327, Percent_Identity=27.82874617737, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281360801, Length=325, Percent_Identity=28, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281360799, Length=326, Percent_Identity=28.8343558282209, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24657891, Length=257, Percent_Identity=25.2918287937743, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644244, Length=324, Percent_Identity=20.9876543209877, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 40662; Mature: 40531

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTRLILKFYALLRLFLGKNARTAWISHPACTGHEPGANHPDSPDRILCIEQALRRAGI
CCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
WQHLQTIEAEEISDTRLALVHSSKYLNRLESCLPQKGKIFRLDNDTAISTGSLSAAHFAA
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCCEEEECCCCEECCCCCCHHHHHC
GSAVQAVDMVMNRKAWHAFCAARPPGHHAGSGKAGGFCLLNNVAAGVMHAIAEYRLKRIA
CHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHEEE
VIDFDVHYGDGTAEIFKDDPRILFFNLFETDLFPFPENNDMPDGGNMVHLPLPPGTGSRT
EEEEEEEECCCHHHHCCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCHH
FREAVRRQWLPRLAAFKPELVLLSAGFDAHRLDESGRLNLHEADFAWLTHKIIQTASGCP
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCCC
GKIVSVLEGGYTLEPLAQSAAEHIRVLAGLGKSDAATAYQKTLDPTKKRFAKPKTGQVRQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCC
PTQSDRYDI
CCCCCCCCC
>Mature Secondary Structure 
SLTRLILKFYALLRLFLGKNARTAWISHPACTGHEPGANHPDSPDRILCIEQALRRAGI
CHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
WQHLQTIEAEEISDTRLALVHSSKYLNRLESCLPQKGKIFRLDNDTAISTGSLSAAHFAA
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCCEEEECCCCEECCCCCCHHHHHC
GSAVQAVDMVMNRKAWHAFCAARPPGHHAGSGKAGGFCLLNNVAAGVMHAIAEYRLKRIA
CHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHEEE
VIDFDVHYGDGTAEIFKDDPRILFFNLFETDLFPFPENNDMPDGGNMVHLPLPPGTGSRT
EEEEEEEECCCHHHHCCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCHH
FREAVRRQWLPRLAAFKPELVLLSAGFDAHRLDESGRLNLHEADFAWLTHKIIQTASGCP
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCCC
GKIVSVLEGGYTLEPLAQSAAEHIRVLAGLGKSDAATAYQKTLDPTKKRFAKPKTGQVRQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCC
PTQSDRYDI
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]