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The map label for this gene is mdaB [H]

Identifier: 161869359

GI number: 161869359

Start: 365321

End: 365899

Strand: Reverse

Name: mdaB [H]

Synonym: NMCC_0365

Alternate gene names: 161869359

Gene position: 365899-365321 (Counterclockwise)

Preceding gene: 161869361

Following gene: 161869355

Centisome position: 16.99

GC content: 47.5

Gene sequence:

>579_bases
ATGAATATTTTATTATTAGACGGCGGCAAGGCGTTCGGACATTCTCACGGCGGGTTAAACCGCACGCTTCACAAAAAAGC
GAAAGAAGTTTTGACCGCGCTCGGACACAATGTTCAAGAAACCGTGATTGATGCCGGCTATGATGTTGAGGCAGAAATCG
AAAAATTCGTTTGGATGGATGCCGTGATTTGGCAGATGCCGGGCTGGTGGATGCACGAGCCTTGGACAGTGAAAAAATAC
ATAGACGAAGTATTAACCGCTGGACACGGCAAACTCTACCAAAGCGACGGCAGACACCGCGTCAATCCGACTGAGGGCTA
CGGCACAGGCGGCTTGTTGCAAGGCAAAAAACATATGCTTTCACTGACTTGGAATGCGCCGATTGAGGCGTTTACCCGCG
AAGGCGATTTCTTTGAAGGCAAAGGCGTTGATGTTTTGTATATGCACTTCCACAAAGCCAACGAGTTTTTGGGTATGACC
CGCCTGTCGACATTCTTATGTAACGATGTGGTTAAAAATCCGCAAGTGGAAAAATACTTGGCAGATTATCAGGCACACTT
GGAAAAAGTGTTCGGCTAA

Upstream 100 bases:

>100_bases
ATTATTTCATTTGACGCAAAAGTGTTTTCTTATTTTTGCACTTTTAAATTATAAAGTAAAACGGCACAATACATTCATCA
ATTCACAAACGAGGTAACAA

Downstream 100 bases:

>100_bases
AAATTTATCTTATAAACAAACAAAGGCAGCCTGAAAGATTGAATGGTCTGCACCCCTAAGGTTGGACTAACCAACCGACT
AAGGTGCAGATTATTTTTTG

Product: modulator of drug activity B

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNILLLDGGKAFGHSHGGLNRTLHKKAKEVLTALGHNVQETVIDAGYDVEAEIEKFVWMDAVIWQMPGWWMHEPWTVKKY
IDEVLTAGHGKLYQSDGRHRVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKANEFLGMT
RLSTFLCNDVVKNPQVEKYLADYQAHLEKVFG

Sequences:

>Translated_192_residues
MNILLLDGGKAFGHSHGGLNRTLHKKAKEVLTALGHNVQETVIDAGYDVEAEIEKFVWMDAVIWQMPGWWMHEPWTVKKY
IDEVLTAGHGKLYQSDGRHRVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKANEFLGMT
RLSTFLCNDVVKNPQVEKYLADYQAHLEKVFG
>Mature_192_residues
MNILLLDGGKAFGHSHGGLNRTLHKKAKEVLTALGHNVQETVIDAGYDVEAEIEKFVWMDAVIWQMPGWWMHEPWTVKKY
IDEVLTAGHGKLYQSDGRHRVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKANEFLGMT
RLSTFLCNDVVKNPQVEKYLADYQAHLEKVFG

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli madB and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=191, Percent_Identity=59.1623036649215, Blast_Score=246, Evalue=5e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 21789; Mature: 21789

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILLLDGGKAFGHSHGGLNRTLHKKAKEVLTALGHNVQETVIDAGYDVEAEIEKFVWMD
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHH
AVIWQMPGWWMHEPWTVKKYIDEVLTAGHGKLYQSDGRHRVNPTEGYGTGGLLQGKKHML
HHHHHCCCCCCCCCEEHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEE
SLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKANEFLGMTRLSTFLCNDVVKNPQVEKYL
EEEECCCHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ADYQAHLEKVFG
HHHHHHHHHHCC
>Mature Secondary Structure
MNILLLDGGKAFGHSHGGLNRTLHKKAKEVLTALGHNVQETVIDAGYDVEAEIEKFVWMD
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHH
AVIWQMPGWWMHEPWTVKKYIDEVLTAGHGKLYQSDGRHRVNPTEGYGTGGLLQGKKHML
HHHHHCCCCCCCCCEEHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEE
SLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKANEFLGMTRLSTFLCNDVVKNPQVEKYL
EEEECCCHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ADYQAHLEKVFG
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]