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The map label for this gene is accB [H]

Identifier: 161869355

GI number: 161869355

Start: 362990

End: 363451

Strand: Reverse

Name: accB [H]

Synonym: NMCC_0361

Alternate gene names: 161869355

Gene position: 363451-362990 (Counterclockwise)

Preceding gene: 161869359

Following gene: 161869354

Centisome position: 16.88

GC content: 58.23

Gene sequence:

>462_bases
ATGGATTTGCGCAAATTAAAAAAACTGATTGATTTGGTTGAAGAATCGGGTATCGCCGAAATCGAAGTAACCGAAGGCGA
GGAAAAAGTCCGCATCACCCGTACCATTGCAGCTGCGGCAGCTCCCGTTTACGCCGCGCCCGTACCTGCCGCCGCGCCGG
CCGTAACGCCTGCCGCCGCACCCGTTGCGGCATCCGCGCCCGCCGCCGCACCTGCCGCCCGCGATTTGTCCGACGCGCAA
AAATCGCCTATGGTCGGCACGTTCTACCGCGCACCCGGCCCGAATGCCGCGCCTTTTGTCGAAGTCGGCCAACAGGTTAA
AGCCGGCGACACGCTGTGCATCATCGAAGCGATGAAGCTGATGAACGAAATCGAAGCCGAAAAATCCGGCACGGTCAAAG
AAATTTTGGTCGAAAACGGTACGCCCGTCGAATTCGGCGAACCGCTCTTCATCATCGGATAA

Upstream 100 bases:

>100_bases
ACCATTCCGCCCGGTTTGCGCCGTTGCCGCAAGCTGGCTGTTTTCTGAAAAACCAACGCAACAACCCGCCGGAACACCGG
CAGCCTTTAAAGGAACAGAA

Downstream 100 bases:

>100_bases
TCCTGTTTTCAGACGGCATAAACTTCCGATGCCGTCTGAAATGCTTTCCCCCTTCGGCGTTCCCGCACCTTTTTTTTTAC
GGACGGGTTGCCGGAACCAC

Product: acetyl-CoA carboxylase biotin carboxyl carrier protein subunit

Products: ADP; phosphate; malonyl-CoA

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MDLRKLKKLIDLVEESGIAEIEVTEGEEKVRITRTIAAAAAPVYAAPVPAAAPAVTPAAAPVAASAPAAAPAARDLSDAQ
KSPMVGTFYRAPGPNAAPFVEVGQQVKAGDTLCIIEAMKLMNEIEAEKSGTVKEILVENGTPVEFGEPLFIIG

Sequences:

>Translated_153_residues
MDLRKLKKLIDLVEESGIAEIEVTEGEEKVRITRTIAAAAAPVYAAPVPAAAPAVTPAAAPVAASAPAAAPAARDLSDAQ
KSPMVGTFYRAPGPNAAPFVEVGQQVKAGDTLCIIEAMKLMNEIEAEKSGTVKEILVENGTPVEFGEPLFIIG
>Mature_153_residues
MDLRKLKKLIDLVEESGIAEIEVTEGEEKVRITRTIAAAAAPVYAAPVPAAAPAVTPAAAPVAASAPAAAPAARDLSDAQ
KSPMVGTFYRAPGPNAAPFVEVGQQVKAGDTLCIIEAMKLMNEIEAEKSGTVKEILVENGTPVEFGEPLFIIG

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789653, Length=158, Percent_Identity=62.0253164556962, Blast_Score=179, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: 6.4.1.2

Molecular weight: Translated: 15821; Mature: 15821

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRKLKKLIDLVEESGIAEIEVTEGEEKVRITRTIAAAAAPVYAAPVPAAAPAVTPAAA
CCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PVAASAPAAAPAARDLSDAQKSPMVGTFYRAPGPNAAPFVEVGQQVKAGDTLCIIEAMKL
CCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCHHCCCCCHHHHHHHHH
MNEIEAEKSGTVKEILVENGTPVEFGEPLFIIG
HHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEC
>Mature Secondary Structure
MDLRKLKKLIDLVEESGIAEIEVTEGEEKVRITRTIAAAAAPVYAAPVPAAAPAVTPAAA
CCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PVAASAPAAAPAARDLSDAQKSPMVGTFYRAPGPNAAPFVEVGQQVKAGDTLCIIEAMKL
CCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCHHCCCCCHHHHHHHHH
MNEIEAEKSGTVKEILVENGTPVEFGEPLFIIG
HHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; acetyl-CoA; HCO3-

Specific reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]