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The map label for this gene is fba [H]

Identifier: 161869346

GI number: 161869346

Start: 351887

End: 352951

Strand: Reverse

Name: fba [H]

Synonym: NMCC_0352

Alternate gene names: 161869346

Gene position: 352951-351887 (Counterclockwise)

Preceding gene: 161869349

Following gene: 161869345

Centisome position: 16.39

GC content: 56.24

Gene sequence:

>1065_bases
ATGGCACTCGTATCCATGCGCCAACTGCTTGATCATGCTGCCGAAAACAGCTACGGCCTGCCCGCGTTCAACGTCAACAA
CCTCGAACAAATGCGCGCCATTATGGAAGCCGCCGACCAAGTCGGCGCGCCCGTCATCGTACAGGCGAGTGCAGGTGCGC
GCAAATATGCGGGCGCGCCGTTTTTGCGCCACCTGATTCTGGCGGCAGTCGAAGAATTTCCGCACATCCCCGTCGTGATG
CACCAAGACCACGGCGCATCGCCCGACGTGTGCCAACGCTCCATCCAACTGGGCTTCTCCTCCGTGATGATGGACGGTTC
GCTGATGGAAGACGGCAAAACCCCTTCTTCTTACGAATACAACGTCAACGCCACACGTACCGTGGTTAATTTCTCCCACG
CTTGCGGCGTATCCGTCGAAGGCGAAATCGGCGTGTTGGGCAACCTCGAAACTGGCGAAGCCGGCGAAGAAGACGGTGTA
GGCGCAGTGGGCAAACTTTCCCACGACCAAATGCTCACCAGCGTCGAAGATGCCGTGCGTTTCGTTAAAGATACCGGCGT
TGACGCATTGGCGATTGCCGTCGGCACCAGCCACGGCGCGTACAAATTCACCCGTCCGCCCACAGGCGACGTGTTGCGTA
TCGACCGCATCAAAGAAATCCACCAAGCCCTGCCCAATACACACATCGTGATGCACGGCTCCAGCTCCGTTCCGCAAGAA
TGGCTGAAAGTCATCAACGAATACGGCGGCAATATCGGCGAAACCTACGGCGTGCCGGTTGAAGAAATCGTCGAAGGCAT
CAAACACGGCGTGCGTAAAGTCAACATCGATACCGACTTGCGCCTTGCTTCCACCGGCGCGGTACGCCGCTACCTTGCCG
AAAACCCGTCCGACTTCGATCCGCGCAAATATTTGAGCAAAACTATTGAAGCGATGAAGCAAATCTGCCTCGACCGCTAC
CTCGCGTTCGGTTGCGAAGGTCAGGCAGGCAAAATCAAACCTGTTTCGTTGGAAAAAATGGCAAGCCGTTATGCCAAGGG
CGAATTGAACCAAATCGTCAAATAA

Upstream 100 bases:

>100_bases
CGCCGTTATCGTTAACATAAAATCAATGAGCCGTTTATGGTTTTTTGCCGCAAAAAACATTATAATCCGCCTTATTTACC
TATTGCCCAAGGAGACACAA

Downstream 100 bases:

>100_bases
CAGGTTGCCGGTAAACAAAATGCCGTCTGAACTGCCGTTCGGACGGTATTTGATTTTTGCTTCTTTGACCTGCCTCATTG
ATGCAGTATGCAAAAAAAGA

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MALVSMRQLLDHAAENSYGLPAFNVNNLEQMRAIMEAADQVGAPVIVQASAGARKYAGAPFLRHLILAAVEEFPHIPVVM
HQDHGASPDVCQRSIQLGFSSVMMDGSLMEDGKTPSSYEYNVNATRTVVNFSHACGVSVEGEIGVLGNLETGEAGEEDGV
GAVGKLSHDQMLTSVEDAVRFVKDTGVDALAIAVGTSHGAYKFTRPPTGDVLRIDRIKEIHQALPNTHIVMHGSSSVPQE
WLKVINEYGGNIGETYGVPVEEIVEGIKHGVRKVNIDTDLRLASTGAVRRYLAENPSDFDPRKYLSKTIEAMKQICLDRY
LAFGCEGQAGKIKPVSLEKMASRYAKGELNQIVK

Sequences:

>Translated_354_residues
MALVSMRQLLDHAAENSYGLPAFNVNNLEQMRAIMEAADQVGAPVIVQASAGARKYAGAPFLRHLILAAVEEFPHIPVVM
HQDHGASPDVCQRSIQLGFSSVMMDGSLMEDGKTPSSYEYNVNATRTVVNFSHACGVSVEGEIGVLGNLETGEAGEEDGV
GAVGKLSHDQMLTSVEDAVRFVKDTGVDALAIAVGTSHGAYKFTRPPTGDVLRIDRIKEIHQALPNTHIVMHGSSSVPQE
WLKVINEYGGNIGETYGVPVEEIVEGIKHGVRKVNIDTDLRLASTGAVRRYLAENPSDFDPRKYLSKTIEAMKQICLDRY
LAFGCEGQAGKIKPVSLEKMASRYAKGELNQIVK
>Mature_353_residues
ALVSMRQLLDHAAENSYGLPAFNVNNLEQMRAIMEAADQVGAPVIVQASAGARKYAGAPFLRHLILAAVEEFPHIPVVMH
QDHGASPDVCQRSIQLGFSSVMMDGSLMEDGKTPSSYEYNVNATRTVVNFSHACGVSVEGEIGVLGNLETGEAGEEDGVG
AVGKLSHDQMLTSVEDAVRFVKDTGVDALAIAVGTSHGAYKFTRPPTGDVLRIDRIKEIHQALPNTHIVMHGSSSVPQEW
LKVINEYGGNIGETYGVPVEEIVEGIKHGVRKVNIDTDLRLASTGAVRRYLAENPSDFDPRKYLSKTIEAMKQICLDRYL
AFGCEGQAGKIKPVSLEKMASRYAKGELNQIVK

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=319, Percent_Identity=32.2884012539185, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=32.5227963525836, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1788072, Length=328, Percent_Identity=27.4390243902439, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38332; Mature: 38201

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00602 ALDOLASE_CLASS_II_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVSMRQLLDHAAENSYGLPAFNVNNLEQMRAIMEAADQVGAPVIVQASAGARKYAGAP
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHCCCH
FLRHLILAAVEEFPHIPVVMHQDHGASPDVCQRSIQLGFSSVMMDGSLMEDGKTPSSYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEE
NVNATRTVVNFSHACGVSVEGEIGVLGNLETGEAGEEDGVGAVGKLSHDQMLTSVEDAVR
CCCCCEEEEEHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FVKDTGVDALAIAVGTSHGAYKFTRPPTGDVLRIDRIKEIHQALPNTHIVMHGSSSVPQE
HHHHCCCCEEEEEEECCCCCEEECCCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCCHHH
WLKVINEYGGNIGETYGVPVEEIVEGIKHGVRKVNIDTDLRLASTGAVRRYLAENPSDFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHHHHCCCCCCC
PRKYLSKTIEAMKQICLDRYLAFGCEGQAGKIKPVSLEKMASRYAKGELNQIVK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALVSMRQLLDHAAENSYGLPAFNVNNLEQMRAIMEAADQVGAPVIVQASAGARKYAGAP
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHCCCH
FLRHLILAAVEEFPHIPVVMHQDHGASPDVCQRSIQLGFSSVMMDGSLMEDGKTPSSYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEE
NVNATRTVVNFSHACGVSVEGEIGVLGNLETGEAGEEDGVGAVGKLSHDQMLTSVEDAVR
CCCCCEEEEEHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FVKDTGVDALAIAVGTSHGAYKFTRPPTGDVLRIDRIKEIHQALPNTHIVMHGSSSVPQE
HHHHCCCCEEEEEEECCCCCEEECCCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCCHHH
WLKVINEYGGNIGETYGVPVEEIVEGIKHGVRKVNIDTDLRLASTGAVRRYLAENPSDFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHHHHCCCCCCC
PRKYLSKTIEAMKQICLDRYLAFGCEGQAGKIKPVSLEKMASRYAKGELNQIVK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]