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The map label for this gene is frpB [H]

Identifier: 161869212

GI number: 161869212

Start: 224098

End: 226260

Strand: Reverse

Name: frpB [H]

Synonym: NMCC_0216

Alternate gene names: 161869212

Gene position: 226260-224098 (Counterclockwise)

Preceding gene: 161869216

Following gene: 161869211

Centisome position: 10.51

GC content: 53.63

Gene sequence:

>2163_bases
ATGAACGCCCCATTATTCCGCCTCAGCCTGCTCTCGCTTACCCTAGCGGCAGGTTTTGCCCACGCGGCAGAAAATAATGC
CAAGGTCGTACTGGATACCGTTACCGTAAAAGGCGACCGCCAAGGCAGCAAAATCCGTACCAACATCGTTACGCTTCAAC
AAAAAGACGAAAGCACCGCAACCGATATGCGCGAACTCTTAAAAGAAGAGCCCTCCATCGATTTCGGCGGCGGCAACGGC
ACGTCCCAATTCCTGACGCTGCGCGGCATGGGTCAGAACTCTGTCGACATCAAGGTGGACAACGCCTATTCCGACAGCCA
AATCCTTTACCACCAAGGCAGATTTATTGTCGATCCCGCTTTGGTTAAAGTCGTTTCCGTACAAAAAGGCGCGGGTTCCG
CCTCTGCCGGTATCGGCGCGACCAACGGCGCGATTATCGCCAAAACCGTCGATGCCCAAGACCTGCTCAAAGGCTTGGAT
AAAAACTGGGGCGTGCGCCTCAACAGCGGCTTTGCCAGCAACGAAGGCGTAAGCTACGGCGCCAGCGTATTCGGAAAAGA
GGGCAACTTCGACGGTTTGTTCTCTTACAACCGCAACGATGAAAAAGATTACGAAGCCGGCAAAGGTTTCCGCAATGTCA
ACGGCGGCAAAACCGTACCGTACAGCGCGCTGGACAAACGCAGCTACCTCGCCAAAATCGGAACAACTTTCGGCGACGAC
GACCACCGCATCGTGTTGAGCCACATGAAAGACCAACACCGGGGCATCCGCACTGTGCGTGAAGAATTTACCGTCGGCGA
CAAAAGTTCACGGATAAATATTGACCGCCAAGCCCCTGCTTACCGCGAAACTACCCAATCCAACACCAACTTGGCGTACA
CGGGTAAAAACCTGGGCTTTGTCGAAAAACTGGATGCCAACGCCTATGTGTTGGAAAAAGAACGCTATTCCGCCGATGAC
AGCGGCACCGGCTACGCAGGCAATATAAAAGGCCCCAACCATACCCGAATCACCACTCGGGGTATGAATTTCAACTTCGA
CAGCCGCCTTGCCGAACAAACCCTGTTGAAATACGGTATCAACTACCGCCATCAGGAAATCAAACCGCAAGCATTTTTGA
ACTCGAAATTCTCCATCCCGACGACAGAAGAGAAAAACGGTCAAAAAGTCGATAAACCGATGGAACAACAAATGAAAGAC
CGTGCAGATGAAGACACTGTTCACGCCTACAAACTTTCCAACCCGACCAAAACCGATACCGGCGTATATGTTGAAGCCAT
TCACGACATCGGCGATTTCACGCTGACCGGCGGGCTGCGTTACGACCGCTTCAAGGTGAAAACCCATGACGGCAAAACCG
TTTCAAGCAGCAACCTTAACCCGAGTTTCGGCGTGATTTGGCAGCCGCACGAACACTGGAGCTTCAGCGCGAGCCACAAC
TACGCCAGCCGCAGCCCGCGCCTGTATGACGCGCTGCAAACCCACGGTAAACGCGGCATCATCTCGATTGCCGACGGCAC
AAAAGCCGAACGCGCGCGCAATACCGAAATCGGCTTCAACTACAACGACGGCACGTTTGCCGCAAACGGCAGCTACTTCT
GGCAGACCATCAAAGACGCGCTTGCCAATCCGCAAAACCGCCACGACTCTGTCGCCGTCCGTGAAGCCGTCAATGCCGGT
TACATCAAAAACCACGGTTACGAATTGGGCGCGTCCTACCGCACCGGCGGCCTGACTGCCAAAGTCGGCGTCAGCCACAG
CAAACCGCGCTTTTACGATACGCACAAAGACAAGCTGTTGAGCGCGAATCCTGAATTTGGCGCACAAGTCGGCCGCACTT
GGACGGCCTCCCTTGCCTACCGCTTCCAAAATCCGAATCTGGAAATCGGCTGGCGCGGCCGTTATGTTCAAAAAGCTACG
GGTTCGATATTGGCGGCAGGTCAAAAAGACCGCAAAGGCAACTTGGAAAACGTTGTACGCAAAGGTTTCGGTGTGAACGA
TGTCTTCGCCAACTGGAAACCGCTGGGCAAAGACACGCTCAATGTCAATCTTTCGGTTAACAACGTGTTCAACACGTTCT
ACTATCCGCACAGCCAACGCTGGACCAATACCCTACCAGGTACTGGACGTGATGTACGCTTGGGCGTGAACTACAAGTTC
TAA

Upstream 100 bases:

>100_bases
CTCTCGTTAATATAAACAAAAATAATTATTATTTTTCTTATCCTGCCAAACCTTAACGGTTTGGATTTACTTCCCTTCAT
ACACTCAAAAGGACGAACAA

Downstream 100 bases:

>100_bases
AACGCACATCCCGAAAAAATGCCGTCTGAAAGCCTTTCAGACGGCATCTGTTCTGATAATTTGATATATAGTGGATTAAC
AAAAACCAGTACGGCGTTGC

Product: iron-regulated outer membrane protein FrpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MNAPLFRLSLLSLTLAAGFAHAAENNAKVVLDTVTVKGDRQGSKIRTNIVTLQQKDESTATDMRELLKEEPSIDFGGGNG
TSQFLTLRGMGQNSVDIKVDNAYSDSQILYHQGRFIVDPALVKVVSVQKGAGSASAGIGATNGAIIAKTVDAQDLLKGLD
KNWGVRLNSGFASNEGVSYGASVFGKEGNFDGLFSYNRNDEKDYEAGKGFRNVNGGKTVPYSALDKRSYLAKIGTTFGDD
DHRIVLSHMKDQHRGIRTVREEFTVGDKSSRINIDRQAPAYRETTQSNTNLAYTGKNLGFVEKLDANAYVLEKERYSADD
SGTGYAGNIKGPNHTRITTRGMNFNFDSRLAEQTLLKYGINYRHQEIKPQAFLNSKFSIPTTEEKNGQKVDKPMEQQMKD
RADEDTVHAYKLSNPTKTDTGVYVEAIHDIGDFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFSASHN
YASRSPRLYDALQTHGKRGIISIADGTKAERARNTEIGFNYNDGTFAANGSYFWQTIKDALANPQNRHDSVAVREAVNAG
YIKNHGYELGASYRTGGLTAKVGVSHSKPRFYDTHKDKLLSANPEFGAQVGRTWTASLAYRFQNPNLEIGWRGRYVQKAT
GSILAAGQKDRKGNLENVVRKGFGVNDVFANWKPLGKDTLNVNLSVNNVFNTFYYPHSQRWTNTLPGTGRDVRLGVNYKF

Sequences:

>Translated_720_residues
MNAPLFRLSLLSLTLAAGFAHAAENNAKVVLDTVTVKGDRQGSKIRTNIVTLQQKDESTATDMRELLKEEPSIDFGGGNG
TSQFLTLRGMGQNSVDIKVDNAYSDSQILYHQGRFIVDPALVKVVSVQKGAGSASAGIGATNGAIIAKTVDAQDLLKGLD
KNWGVRLNSGFASNEGVSYGASVFGKEGNFDGLFSYNRNDEKDYEAGKGFRNVNGGKTVPYSALDKRSYLAKIGTTFGDD
DHRIVLSHMKDQHRGIRTVREEFTVGDKSSRINIDRQAPAYRETTQSNTNLAYTGKNLGFVEKLDANAYVLEKERYSADD
SGTGYAGNIKGPNHTRITTRGMNFNFDSRLAEQTLLKYGINYRHQEIKPQAFLNSKFSIPTTEEKNGQKVDKPMEQQMKD
RADEDTVHAYKLSNPTKTDTGVYVEAIHDIGDFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFSASHN
YASRSPRLYDALQTHGKRGIISIADGTKAERARNTEIGFNYNDGTFAANGSYFWQTIKDALANPQNRHDSVAVREAVNAG
YIKNHGYELGASYRTGGLTAKVGVSHSKPRFYDTHKDKLLSANPEFGAQVGRTWTASLAYRFQNPNLEIGWRGRYVQKAT
GSILAAGQKDRKGNLENVVRKGFGVNDVFANWKPLGKDTLNVNLSVNNVFNTFYYPHSQRWTNTLPGTGRDVRLGVNYKF
>Mature_720_residues
MNAPLFRLSLLSLTLAAGFAHAAENNAKVVLDTVTVKGDRQGSKIRTNIVTLQQKDESTATDMRELLKEEPSIDFGGGNG
TSQFLTLRGMGQNSVDIKVDNAYSDSQILYHQGRFIVDPALVKVVSVQKGAGSASAGIGATNGAIIAKTVDAQDLLKGLD
KNWGVRLNSGFASNEGVSYGASVFGKEGNFDGLFSYNRNDEKDYEAGKGFRNVNGGKTVPYSALDKRSYLAKIGTTFGDD
DHRIVLSHMKDQHRGIRTVREEFTVGDKSSRINIDRQAPAYRETTQSNTNLAYTGKNLGFVEKLDANAYVLEKERYSADD
SGTGYAGNIKGPNHTRITTRGMNFNFDSRLAEQTLLKYGINYRHQEIKPQAFLNSKFSIPTTEEKNGQKVDKPMEQQMKD
RADEDTVHAYKLSNPTKTDTGVYVEAIHDIGDFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFSASHN
YASRSPRLYDALQTHGKRGIISIADGTKAERARNTEIGFNYNDGTFAANGSYFWQTIKDALANPQNRHDSVAVREAVNAG
YIKNHGYELGASYRTGGLTAKVGVSHSKPRFYDTHKDKLLSANPEFGAQVGRTWTASLAYRFQNPNLEIGWRGRYVQKAT
GSILAAGQKDRKGNLENVVRKGFGVNDVFANWKPLGKDTLNVNLSVNNVFNTFYYPHSQRWTNTLPGTGRDVRLGVNYKF

Specific function: This protein is involved in the initial step of iron uptake by binding hemin, an iron chelatin siderophore that allows the bacteria to extract iron from the environment [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR011276
- InterPro:   IPR010949 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79631; Mature: 79631

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPLFRLSLLSLTLAAGFAHAAENNAKVVLDTVTVKGDRQGSKIRTNIVTLQQKDESTA
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCEEEEEEEEEECCCCCHH
TDMRELLKEEPSIDFGGGNGTSQFLTLRGMGQNSVDIKVDNAYSDSQILYHQGRFIVDPA
HHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEEECCCEEECHH
LVKVVSVQKGAGSASAGIGATNGAIIAKTVDAQDLLKGLDKNWGVRLNSGFASNEGVSYG
HEEEEEECCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCEEEECCCCCCCCCCCC
ASVFGKEGNFDGLFSYNRNDEKDYEAGKGFRNVNGGKTVPYSALDKRSYLAKIGTTFGDD
HHHCCCCCCCCCEEECCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
DHRIVLSHMKDQHRGIRTVREEFTVGDKSSRINIDRQAPAYRETTQSNTNLAYTGKNLGF
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCEEEEECCCCCC
VEKLDANAYVLEKERYSADDSGTGYAGNIKGPNHTRITTRGMNFNFDSRLAEQTLLKYGI
EEEECCCEEEEEHHHCCCCCCCCCEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCC
NYRHQEIKPQAFLNSKFSIPTTEEKNGQKVDKPMEQQMKDRADEDTVHAYKLSNPTKTDT
CCCHHHCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCC
GVYVEAIHDIGDFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFSASHN
CEEEEEECCCCCEEEECCEEEEEEEEEECCCCEEECCCCCCCCCEEECCCCCCEECCCCC
YASRSPRLYDALQTHGKRGIISIADGTKAERARNTEIGFNYNDGTFAANGSYFWQTIKDA
CCCCCCHHHHHHHHCCCCCEEEECCCCCHHHCCCCCCCEEECCCCEEECCHHHHHHHHHH
LANPQNRHDSVAVREAVNAGYIKNHGYELGASYRTGGLTAKVGVSHSKPRFYDTHKDKLL
HCCCCCCCCHHHHHHHHCCCEEECCCEEECCCEECCCEEEEECCCCCCCCCCCCCCCCEE
SANPEFGAQVGRTWTASLAYRFQNPNLEIGWRGRYVQKATGSILAAGQKDRKGNLENVVR
CCCCCHHHHHCCEEEEEEEEEECCCCEEEEECCCEEECCCCCEEECCCCCCCCCHHHHHH
KGFGVNDVFANWKPLGKDTLNVNLSVNNVFNTFYYPHSQRWTNTLPGTGRDVRLGVNYKF
HCCCCCHHHCCCCCCCCCEEEEEEEECCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MNAPLFRLSLLSLTLAAGFAHAAENNAKVVLDTVTVKGDRQGSKIRTNIVTLQQKDESTA
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCEEEEEEEEEECCCCCHH
TDMRELLKEEPSIDFGGGNGTSQFLTLRGMGQNSVDIKVDNAYSDSQILYHQGRFIVDPA
HHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEEECCCEEECHH
LVKVVSVQKGAGSASAGIGATNGAIIAKTVDAQDLLKGLDKNWGVRLNSGFASNEGVSYG
HEEEEEECCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCEEEECCCCCCCCCCCC
ASVFGKEGNFDGLFSYNRNDEKDYEAGKGFRNVNGGKTVPYSALDKRSYLAKIGTTFGDD
HHHCCCCCCCCCEEECCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
DHRIVLSHMKDQHRGIRTVREEFTVGDKSSRINIDRQAPAYRETTQSNTNLAYTGKNLGF
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCEEEEECCCCCC
VEKLDANAYVLEKERYSADDSGTGYAGNIKGPNHTRITTRGMNFNFDSRLAEQTLLKYGI
EEEECCCEEEEEHHHCCCCCCCCCEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCC
NYRHQEIKPQAFLNSKFSIPTTEEKNGQKVDKPMEQQMKDRADEDTVHAYKLSNPTKTDT
CCCHHHCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCC
GVYVEAIHDIGDFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFSASHN
CEEEEEECCCCCEEEECCEEEEEEEEEECCCCEEECCCCCCCCCEEECCCCCCEECCCCC
YASRSPRLYDALQTHGKRGIISIADGTKAERARNTEIGFNYNDGTFAANGSYFWQTIKDA
CCCCCCHHHHHHHHCCCCCEEEECCCCCHHHCCCCCCCEEECCCCEEECCHHHHHHHHHH
LANPQNRHDSVAVREAVNAGYIKNHGYELGASYRTGGLTAKVGVSHSKPRFYDTHKDKLL
HCCCCCCCCHHHHHHHHCCCEEECCCEEECCCEECCCEEEEECCCCCCCCCCCCCCCCEE
SANPEFGAQVGRTWTASLAYRFQNPNLEIGWRGRYVQKATGSILAAGQKDRKGNLENVVR
CCCCCHHHHHCCEEEEEEEEEECCCCEEEEECCCEEECCCCCEEECCCCCCCCCHHHHHH
KGFGVNDVFANWKPLGKDTLNVNLSVNNVFNTFYYPHSQRWTNTLPGTGRDVRLGVNYKF
HCCCCCHHHCCCCCCCCCEEEEEEEECCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1425573 [H]