Click here to switch to the map view.

The map label for this gene is gntK [H]

Identifier: 161869174

GI number: 161869174

Start: 173878

End: 174396

Strand: Reverse

Name: gntK [H]

Synonym: NMCC_0171

Alternate gene names: 161869174

Gene position: 174396-173878 (Counterclockwise)

Preceding gene: 161869175

Following gene: 161869171

Centisome position: 8.1

GC content: 58.38

Gene sequence:

>519_bases
ATGACTACGCATTTTGTCGTTATGGGCGTATGCGGCTGCGGCAAGACCACCGCCGCGCTGTCCCTGCAGAAACACCTCGG
TCAATGTCCCCATGCCGAAGGCGACGAGTTCCACACCCAAGCCAACCGCGACAAGATGGGCGCGGGTATTCCGCTGACCG
ATGAAGACCGCTATCCGTGGTTGGGCAATCTGCGCGACTGGATGACGCAACAGGCGCAAAACGGTGCGAACCACACCATC
GTAACCTGTTCCGCCCTCAAACGCGGCTACCGCGACATTCTGCGCGGAGCCGAAGGCAAAGCTGCTTTCATCCACCTCAG
TCCGCCGCAAGACATCAACCTCGAGCGCATGATGTCGCGCAAAGGACATTACATGAAAGCAGGGATGCTCGATTCGCAAC
TGGAAATCCTCGAGGAACTGGGCGAAGGCGAATACGGGGTCAAAATCGCCAACCCCGGCACGCCCGAAGCGGTCGAAGCC
GATATTCTGAACTGGGTTGCCTCGGAAAACCTGCTTTGA

Upstream 100 bases:

>100_bases
CTGAAAACCTGGACGGTCAACCAAACCCTCATCGCACTCATCGGCTTTGCCTTGTCCGCACTGCTGTTCGCCATCGTCTG
ACAGACGGAAAGGATAGTAA

Downstream 100 bases:

>100_bases
AGCAATATGCCGTCTGAAGCCCGACACAGGATGGGTTTCAGACGGCATAAACATCGGGAACAGAATGGATTACATTGATT
TATAGTGGATTAACAAAAAC

Product: thermoresistant gluconokinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MTTHFVVMGVCGCGKTTAALSLQKHLGQCPHAEGDEFHTQANRDKMGAGIPLTDEDRYPWLGNLRDWMTQQAQNGANHTI
VTCSALKRGYRDILRGAEGKAAFIHLSPPQDINLERMMSRKGHYMKAGMLDSQLEILEELGEGEYGVKIANPGTPEAVEA
DILNWVASENLL

Sequences:

>Translated_172_residues
MTTHFVVMGVCGCGKTTAALSLQKHLGQCPHAEGDEFHTQANRDKMGAGIPLTDEDRYPWLGNLRDWMTQQAQNGANHTI
VTCSALKRGYRDILRGAEGKAAFIHLSPPQDINLERMMSRKGHYMKAGMLDSQLEILEELGEGEYGVKIANPGTPEAVEA
DILNWVASENLL
>Mature_171_residues
TTHFVVMGVCGCGKTTAALSLQKHLGQCPHAEGDEFHTQANRDKMGAGIPLTDEDRYPWLGNLRDWMTQQAQNGANHTIV
TCSALKRGYRDILRGAEGKAAFIHLSPPQDINLERMMSRKGHYMKAGMLDSQLEILEELGEGEYGVKIANPGTPEAVEAD
ILNWVASENLL

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=164, Percent_Identity=37.8048780487805, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI87082265, Length=152, Percent_Identity=38.1578947368421, Blast_Score=105, Evalue=1e-24,
Organism=Escherichia coli, GI1790719, Length=134, Percent_Identity=41.7910447761194, Blast_Score=99, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25146487, Length=137, Percent_Identity=43.0656934306569, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320454, Length=176, Percent_Identity=35.7954545454545, Blast_Score=98, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18921; Mature: 18790

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHFVVMGVCGCGKTTAALSLQKHLGQCPHAEGDEFHTQANRDKMGAGIPLTDEDRYPW
CCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCC
LGNLRDWMTQQAQNGANHTIVTCSALKRGYRDILRGAEGKAAFIHLSPPQDINLERMMSR
CCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHH
KGHYMKAGMLDSQLEILEELGEGEYGVKIANPGTPEAVEADILNWVASENLL
CCCEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTHFVVMGVCGCGKTTAALSLQKHLGQCPHAEGDEFHTQANRDKMGAGIPLTDEDRYPW
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCC
LGNLRDWMTQQAQNGANHTIVTCSALKRGYRDILRGAEGKAAFIHLSPPQDINLERMMSR
CCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHH
KGHYMKAGMLDSQLEILEELGEGEYGVKIANPGTPEAVEADILNWVASENLL
CCCEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]