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The map label for this gene is cysS [H]

Identifier: 161869111

GI number: 161869111

Start: 103164

End: 105263

Strand: Direct

Name: cysS [H]

Synonym: NMCC_0102

Alternate gene names: 161869111

Gene position: 103164-105263 (Clockwise)

Preceding gene: 161869110

Following gene: 161869112

Centisome position: 4.79

GC content: 48.24

Gene sequence:

>2100_bases
ATGACTACAATCACAGAAAAGAGATTAACCTTTGCTTTTCCTGAAGATTATTACGTTACCAAGTATGACGAATGGGAACA
TTATAAAATTTTTCAGAACAGTTGTAATTTACGTAATAAAATTGATACAAATGAAAAGGGAAAGAACGGGATAAATCAAA
GTGTAGATGACGATAATGGCAGCTCAGGTGTAGATATAATAGCCCTTCATGAGTCGACACTTTGGCTAATCGAAATTAAA
GATTATTACCGACTTGGGCTTGAGCCAAATGCCCAATCAATAGATGAAAAACTTTCTGACCTACCATATTTAATCGCAAG
AAAAATTCGAGATTCATTGGCAGGATTGGTTTCTGCTAAATTTAAAGCAGAAAAACAGGAAGAAAAAGATTTTTCTCGCT
TGGCTTTAGATTGTAACGAAATAAAAATAGTCCTTCATATTGAAATGCCTAATATAAGAAGTAAACTTTATCCCTCGTCA
TCAGATTTAGCAAACTTATTAAAAGATAAGTTTAAATTATCAGAATTTACAAAAAATTTTGCAAACTGTTATGCAGAACC
AATTTTCACAAATATCAGCCATATTAATAATCCGCAACTGCGTAATGTTCCTTGGTCCGTATCTACAGGAACAGAACAGA
AATTATCATCCGAGCAACAAAGATTAATCCATAATCCCATGACCACCATCTACAACACCCTTACCCGCCAAAAAGAACCC
TTTGCCCCCATCGACCCTGAAAACGTGCGTATGTACGTTTGCGGCATGACCGTTTACGACTATTGCCACTTAGGCCATGC
CCGTGTGATGGTTGTGTTCGACATGATTGCCCGTTGGTTGCGCGAGTGCGGCTATCCGCTCACTTATGTACGCAACATCA
CCGACATCGACGATAAAATCATTGCCCGTGCGGCTGAAAACGGCGAGACTATCGGCGAACTGACCGCGCGTTTCATTCAG
GCTATGCACGAAGATGCCGATGCTTTGGGTGTGTTGCGTCCCGATATCGAGCCGAAGGCGACGGAAAACATCCCGCAAAT
GATTGCCATGATTGAAACCCTGATTCAAAACGGCAAGGCATATCCTGCCGCAAATGGCGACGTTTACTACGCCGTGCGCG
AGTTTGCCGCTTACGGACAACTGTCGGGCAAATCGTTGGACGACCTGCGCGCGGGCGAACGCGTGGAAGTGGACGGTTTC
AAACGCGATCCGCTTGATTTTGTATTGTGGAAAGCGGCGAAAGCAGGCGAACCGGCGTGGGAAAGCCCGTGGGGCAACGG
CCGTCCGGGTTGGCACATTGAATGCTCTGCCATGAGTGAAAACCTGTTCGGCGATACGTTCGACATTCACGGCGGCGGCG
CGGATTTGCAGTTCCCTCATCATGAAAATGAAATCGCCCAAAGCGTCGGCGCGACGGGGCATACCTGCGGTCATCATCAC
GCGCAAACCCACCACGGGCAAAGCATCGCCAGCCACGTCAAATACTGGCTGCACAACGGCTTCATCCGCGTGGATGGCGA
AAAAATGTCGAAATCGCTGGGCAACTTCTTCACCATCCGCGAAGTATTGAAACAATACGACCCTGAAGTTGTGCGTTTCT
TCATCCTGCGCGCCCACTACCGCAGCCCGTTGAATTACTCCGACGCACATTTGGACGACGCAAAAGGTGCGCTGACCCGC
CTGTACACTACATTGAAAAACACACCAGCGGCTGAGTTTGACTTATCTGAAAACGTCAACGACTACACCCGCCGTTTCTA
CGCCGCCATGAACGACGATTTTGGTACGGTCGAAGCGGTTGCCGTGTTGTTCGAACTGGCAGGCGAAGTGAACAAAACCA
ATGACGCACAGCTCGCCGGCTGCCTGAAAGCCTTGGGCGGCATCATCGGACTGCTGCAACGCGATCCGACCGAGTTCCTG
CAAGGCGGCGCGGCTTCAGACGGTCTCTCCAACGAAGAAATCGAAGACTTGATTGCCCGGCGGAAACAGGCGCGCTCCGA
TAAAAACTGGGCGGAATCCGACCGCATTCGCGACCTTCTGAACGAACACAAAATCATTTTGGAAGACAACGCCGGCGGCA
CGACTTGGCGGCGCGGTTGA

Upstream 100 bases:

>100_bases
AGTGGAGCAAGGGAACAGTATTAATGATTTGAACACATTGATATTGTTAGATGAAAACATTATGCAGGCAGACAGGTATC
TGAATATTTGAGGTTAAGCT

Downstream 100 bases:

>100_bases
AATCCATCGAAAAGGGTAAATGTGCCGCATTTTGCCCTTTTTTGTTCAGACGGCATTTTTATTGTGAGAACTTATTTTTA
TTATGCTTAAAATCATTTCC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 699; Mature: 698

Protein sequence:

>699_residues
MTTITEKRLTFAFPEDYYVTKYDEWEHYKIFQNSCNLRNKIDTNEKGKNGINQSVDDDNGSSGVDIIALHESTLWLIEIK
DYYRLGLEPNAQSIDEKLSDLPYLIARKIRDSLAGLVSAKFKAEKQEEKDFSRLALDCNEIKIVLHIEMPNIRSKLYPSS
SDLANLLKDKFKLSEFTKNFANCYAEPIFTNISHINNPQLRNVPWSVSTGTEQKLSSEQQRLIHNPMTTIYNTLTRQKEP
FAPIDPENVRMYVCGMTVYDYCHLGHARVMVVFDMIARWLRECGYPLTYVRNITDIDDKIIARAAENGETIGELTARFIQ
AMHEDADALGVLRPDIEPKATENIPQMIAMIETLIQNGKAYPAANGDVYYAVREFAAYGQLSGKSLDDLRAGERVEVDGF
KRDPLDFVLWKAAKAGEPAWESPWGNGRPGWHIECSAMSENLFGDTFDIHGGGADLQFPHHENEIAQSVGATGHTCGHHH
AQTHHGQSIASHVKYWLHNGFIRVDGEKMSKSLGNFFTIREVLKQYDPEVVRFFILRAHYRSPLNYSDAHLDDAKGALTR
LYTTLKNTPAAEFDLSENVNDYTRRFYAAMNDDFGTVEAVAVLFELAGEVNKTNDAQLAGCLKALGGIIGLLQRDPTEFL
QGGAASDGLSNEEIEDLIARRKQARSDKNWAESDRIRDLLNEHKIILEDNAGGTTWRRG

Sequences:

>Translated_699_residues
MTTITEKRLTFAFPEDYYVTKYDEWEHYKIFQNSCNLRNKIDTNEKGKNGINQSVDDDNGSSGVDIIALHESTLWLIEIK
DYYRLGLEPNAQSIDEKLSDLPYLIARKIRDSLAGLVSAKFKAEKQEEKDFSRLALDCNEIKIVLHIEMPNIRSKLYPSS
SDLANLLKDKFKLSEFTKNFANCYAEPIFTNISHINNPQLRNVPWSVSTGTEQKLSSEQQRLIHNPMTTIYNTLTRQKEP
FAPIDPENVRMYVCGMTVYDYCHLGHARVMVVFDMIARWLRECGYPLTYVRNITDIDDKIIARAAENGETIGELTARFIQ
AMHEDADALGVLRPDIEPKATENIPQMIAMIETLIQNGKAYPAANGDVYYAVREFAAYGQLSGKSLDDLRAGERVEVDGF
KRDPLDFVLWKAAKAGEPAWESPWGNGRPGWHIECSAMSENLFGDTFDIHGGGADLQFPHHENEIAQSVGATGHTCGHHH
AQTHHGQSIASHVKYWLHNGFIRVDGEKMSKSLGNFFTIREVLKQYDPEVVRFFILRAHYRSPLNYSDAHLDDAKGALTR
LYTTLKNTPAAEFDLSENVNDYTRRFYAAMNDDFGTVEAVAVLFELAGEVNKTNDAQLAGCLKALGGIIGLLQRDPTEFL
QGGAASDGLSNEEIEDLIARRKQARSDKNWAESDRIRDLLNEHKIILEDNAGGTTWRRG
>Mature_698_residues
TTITEKRLTFAFPEDYYVTKYDEWEHYKIFQNSCNLRNKIDTNEKGKNGINQSVDDDNGSSGVDIIALHESTLWLIEIKD
YYRLGLEPNAQSIDEKLSDLPYLIARKIRDSLAGLVSAKFKAEKQEEKDFSRLALDCNEIKIVLHIEMPNIRSKLYPSSS
DLANLLKDKFKLSEFTKNFANCYAEPIFTNISHINNPQLRNVPWSVSTGTEQKLSSEQQRLIHNPMTTIYNTLTRQKEPF
APIDPENVRMYVCGMTVYDYCHLGHARVMVVFDMIARWLRECGYPLTYVRNITDIDDKIIARAAENGETIGELTARFIQA
MHEDADALGVLRPDIEPKATENIPQMIAMIETLIQNGKAYPAANGDVYYAVREFAAYGQLSGKSLDDLRAGERVEVDGFK
RDPLDFVLWKAAKAGEPAWESPWGNGRPGWHIECSAMSENLFGDTFDIHGGGADLQFPHHENEIAQSVGATGHTCGHHHA
QTHHGQSIASHVKYWLHNGFIRVDGEKMSKSLGNFFTIREVLKQYDPEVVRFFILRAHYRSPLNYSDAHLDDAKGALTRL
YTTLKNTPAAEFDLSENVNDYTRRFYAAMNDDFGTVEAVAVLFELAGEVNKTNDAQLAGCLKALGGIIGLLQRDPTEFLQ
GGAASDGLSNEEIEDLIARRKQARSDKNWAESDRIRDLLNEHKIILEDNAGGTTWRRG

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=404, Percent_Identity=42.0792079207921, Blast_Score=273, Evalue=3e-73,
Organism=Homo sapiens, GI62240992, Length=323, Percent_Identity=34.984520123839, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI21269877, Length=271, Percent_Identity=38.0073800738007, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI10835051, Length=271, Percent_Identity=38.0073800738007, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI303304987, Length=323, Percent_Identity=34.984520123839, Blast_Score=196, Evalue=6e-50,
Organism=Escherichia coli, GI1786737, Length=483, Percent_Identity=54.0372670807453, Blast_Score=493, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17509795, Length=445, Percent_Identity=31.4606741573034, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17509797, Length=445, Percent_Identity=31.4606741573034, Blast_Score=184, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6324082, Length=342, Percent_Identity=33.9181286549708, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI19922218, Length=513, Percent_Identity=34.8927875243665, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI19922364, Length=338, Percent_Identity=35.7988165680473, Blast_Score=199, Evalue=5e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 79003; Mature: 78871

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTITEKRLTFAFPEDYYVTKYDEWEHYKIFQNSCNLRNKIDTNEKGKNGINQSVDDDNG
CCCCCCCCEEEECCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSGVDIIALHESTLWLIEIKDYYRLGLEPNAQSIDEKLSDLPYLIARKIRDSLAGLVSAK
CCCEEEEEEECCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKAEKQEEKDFSRLALDCNEIKIVLHIEMPNIRSKLYPSSSDLANLLKDKFKLSEFTKNF
HHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ANCYAEPIFTNISHINNPQLRNVPWSVSTGTEQKLSSEQQRLIHNPMTTIYNTLTRQKEP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCC
FAPIDPENVRMYVCGMTVYDYCHLGHARVMVVFDMIARWLRECGYPLTYVRNITDIDDKI
CCCCCCCCCEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCHHHH
IARAAENGETIGELTARFIQAMHEDADALGVLRPDIEPKATENIPQMIAMIETLIQNGKA
HHHHHCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
YPAANGDVYYAVREFAAYGQLSGKSLDDLRAGERVEVDGFKRDPLDFVLWKAAKAGEPAW
CCCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCCCC
ESPWGNGRPGWHIECSAMSENLFGDTFDIHGGGADLQFPHHENEIAQSVGATGHTCGHHH
CCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
AQTHHGQSIASHVKYWLHNGFIRVDGEKMSKSLGNFFTIREVLKQYDPEVVRFFILRAHY
CHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
RSPLNYSDAHLDDAKGALTRLYTTLKNTPAAEFDLSENVNDYTRRFYAAMNDDFGTVEAV
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
AVLFELAGEVNKTNDAQLAGCLKALGGIIGLLQRDPTEFLQGGAASDGLSNEEIEDLIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHH
RKQARSDKNWAESDRIRDLLNEHKIILEDNAGGTTWRRG
HHHHCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TTITEKRLTFAFPEDYYVTKYDEWEHYKIFQNSCNLRNKIDTNEKGKNGINQSVDDDNG
CCCCCCCEEEECCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSGVDIIALHESTLWLIEIKDYYRLGLEPNAQSIDEKLSDLPYLIARKIRDSLAGLVSAK
CCCEEEEEEECCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKAEKQEEKDFSRLALDCNEIKIVLHIEMPNIRSKLYPSSSDLANLLKDKFKLSEFTKNF
HHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ANCYAEPIFTNISHINNPQLRNVPWSVSTGTEQKLSSEQQRLIHNPMTTIYNTLTRQKEP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCC
FAPIDPENVRMYVCGMTVYDYCHLGHARVMVVFDMIARWLRECGYPLTYVRNITDIDDKI
CCCCCCCCCEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCHHHH
IARAAENGETIGELTARFIQAMHEDADALGVLRPDIEPKATENIPQMIAMIETLIQNGKA
HHHHHCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
YPAANGDVYYAVREFAAYGQLSGKSLDDLRAGERVEVDGFKRDPLDFVLWKAAKAGEPAW
CCCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCCCC
ESPWGNGRPGWHIECSAMSENLFGDTFDIHGGGADLQFPHHENEIAQSVGATGHTCGHHH
CCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
AQTHHGQSIASHVKYWLHNGFIRVDGEKMSKSLGNFFTIREVLKQYDPEVVRFFILRAHY
CHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
RSPLNYSDAHLDDAKGALTRLYTTLKNTPAAEFDLSENVNDYTRRFYAAMNDDFGTVEAV
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
AVLFELAGEVNKTNDAQLAGCLKALGGIIGLLQRDPTEFLQGGAASDGLSNEEIEDLIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHH
RKQARSDKNWAESDRIRDLLNEHKIILEDNAGGTTWRRG
HHHHCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]