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The map label for this gene is pilE [H]

Identifier: 161869040

GI number: 161869040

Start: 18148

End: 18528

Strand: Reverse

Name: pilE [H]

Synonym: NMCC_0023

Alternate gene names: 161869040

Gene position: 18528-18148 (Counterclockwise)

Preceding gene: 161869041

Following gene: 161869037

Centisome position: 0.86

GC content: 55.64

Gene sequence:

>381_bases
TTGGCCGAAGGTCAAAAATCAGCCGTTACCGAGTATTACCTGAATCACGGCATATGGCCCGCCAACAACAATTCTGCCGG
CGTGGCAACCTCCGCCAACATCAAAGGCAAATATGTTGAGAAAGTTGAAGTCAAAAACGGCGTCGTTACCGCCACAATGC
TTTCAACCGGCGTAAACAACGAAATCAAAGGCAAACAACTCTCCCTGTGGGCCAAGCGTCAAGACGGTTCGGTAAAATGG
TTCTGCGGACAGCCGGTTAAGCGCGCCAACGCCAACGGCGCCACCAACGCCACCGCCGACGGCGTTACCGCCGACAGCGG
CAAGCAGATCGACACCAAGCACCTGCCGTCAACCTGCCGCGACGCATCATCTGCCAGCTAA

Upstream 100 bases:

>100_bases
GGGATCTAGGATGTAAAATCTCAAGAAACCGTTTTCCCGATAAGTTTCCGTACCGACAAGGCTGGATTCCCGCCTGCGCG
GGAATGACGAAGCCATTCTT

Downstream 100 bases:

>100_bases
GGTAAATTATACCATAAATTTTAAATAAATCAAGCGGTAAGTGATTTTCCACGGCCACTCGGATTAATCCGGGTGGCTTC
ATTTTAAGGGTTTGCAAGGC

Product: fimbrial protein precursor (pilin)

Products: NA

Alternate protein names: Pilin [H]

Number of amino acids: Translated: 126; Mature: 125

Protein sequence:

>126_residues
MAEGQKSAVTEYYLNHGIWPANNNSAGVATSANIKGKYVEKVEVKNGVVTATMLSTGVNNEIKGKQLSLWAKRQDGSVKW
FCGQPVKRANANGATNATADGVTADSGKQIDTKHLPSTCRDASSAS

Sequences:

>Translated_126_residues
MAEGQKSAVTEYYLNHGIWPANNNSAGVATSANIKGKYVEKVEVKNGVVTATMLSTGVNNEIKGKQLSLWAKRQDGSVKW
FCGQPVKRANANGATNATADGVTADSGKQIDTKHLPSTCRDASSAS
>Mature_125_residues
AEGQKSAVTEYYLNHGIWPANNNSAGVATSANIKGKYVEKVEVKNGVVTATMLSTGVNNEIKGKQLSLWAKRQDGSVKWF
CGQPVKRANANGATNATADGVTADSGKQIDTKHLPSTCRDASSAS

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 13271; Mature: 13140

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGQKSAVTEYYLNHGIWPANNNSAGVATSANIKGKYVEKVEVKNGVVTATMLSTGVNN
CCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCEEEEEEECCCCCC
EIKGKQLSLWAKRQDGSVKWFCGQPVKRANANGATNATADGVTADSGKQIDTKHLPSTCR
CCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCHHC
DASSAS
CCCCCC
>Mature Secondary Structure 
AEGQKSAVTEYYLNHGIWPANNNSAGVATSANIKGKYVEKVEVKNGVVTATMLSTGVNN
CCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCEEEEEEECCCCCC
EIKGKQLSLWAKRQDGSVKWFCGQPVKRANANGATNATADGVTADSGKQIDTKHLPSTCR
CCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCHHC
DASSAS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 9515697 [H]