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The map label for this gene is hcp

Identifier: 161760530

GI number: 161760530

Start: 2663073

End: 2664716

Strand: Reverse

Name: hcp

Synonym: TTE2772

Alternate gene names: 161760530

Gene position: 2664716-2663073 (Counterclockwise)

Preceding gene: 20809102

Following gene: 20809099

Centisome position: 99.08

GC content: 37.9

Gene sequence:

>1644_bases
ATGTTTTGTTATCAATGTCAGGAGGCATTGAAGAATACAGGATGTACGACAATTGGTGTGTGCGGCAAAACAGCCGATGT
AGCAAACCTTCAGGATTTGCTAATTTTTACCCTGAAGGGCATATCTTTTTTAAACTTAAAGGCAAGAGAAGTCGGTGTAA
ATAAAGAAAAAACAGATCGCTTCCTAATTGAAGGCTTATTTTCTACAATTACAAATGTGAATTTTGACAGGAACTTCTTC
TTAAGAAAAATAAAAGAAGCAGTGGCATTGAGGGATGAAATCAAAGAAGACCTTAGAAATAAAGGTGTAAGAGTAGACGA
ATATAAAAATATAGATGCCATTTCATGGACTTATGGCACGGATGCCGATATAGAAGCAATTTCTCAGGAAGTAGGAGTTT
TATCTACAGAAGATGAAGACATAAGGTCTTTAAGGGAGTTAATAACTTATGGTGTAAAGGGTATGGCAGCCTATGCATAT
CATGCATATCAACTGGGTTATAAAGATGACAATATATTTAAGTTTATGGAGAAAGCATTGGCTAAGGTTTTAGATGACAG
TTTGACAGTGGATGACTATGTGGCTTTGGCAATGGAGACAGGGAAATACGGCGTAGATACAATGGCACTTCTTGACAAAG
CCAATACTTCTACCTACGGTCATCCTGAGATAACAAAAGTCAATATTGGAGTGAGAAATAATCCAGGAATATTGGTAAGC
GGTCACGATTTAAAGGACTTAGAACAGCTTCTTGAGCAAACTGCTGGCACAGGTGTAGATGTATATACTCATGGAGAGAT
GTTACCAGCTCACTATTATCCTGCTTTTAAGAAATATCCTCACTTTGTAGGCAATTATGGCAATGCATGGTGGCAGCAGG
ACAAGGAATTCGAACTATTTAACGGACCAATTTTAATGACTACAAACTGCCTCATTCCGCCTAAAGACTCTTATAAAGAC
AGAGTCTACACTACAGGCGTCGTAGGCTTTGAAGGGGTAAAATACATTCCTGAAGGACCAGATGGTAAGAAAGATTTCTC
AGAGATAATTGAGCATGCCAAAAGATGCAAACCTCCTGTAGAGATTGAAAGAGGAGAAATAATAGGAGGCTTTGCTCACA
ACCAGGTTTTACAGTTAGCGGATAAGATTGTAGAAGCAGTAAAGACAGGAGCAATAAAGAGATTCTTTGTAATGGCAGGC
TGCGACGGAAGAATGAAAAGTAGAACCTATTATACAGAATTTGCCAAAGCTCTTCCAAAAGACACAGTGATTCTAACCGC
AGGATGTGCAAAATACAGATACAACAAGCTAAATCTTGGAGACATAGATGGCATTCCAAGAGTATTAGATGCCGGACAGT
GCAACGACTCTTATTCCCTTGCTGTAATAGCAATGAAGCTTAAAGAAATATTCGGATTAAACGACATAAACGAACTTCCT
ATATCATATAACATTGCATGGTATGAACAAAAAGCTGTAATAGTACTTCTGGCACTACTTTACCTTGGAGTAAAAAATAT
TCACTTAGGCCCAACACTTCCTGCTTTCCTATCACCAAATGTGACAAAAGTATTAGTTGAGAAATTTGGTATTGGTGGCA
TAACAAACGTAGAAGATGACTTAAAAATGTTCTTAGGAGCGTAA

Upstream 100 bases:

>100_bases
GACTTTTTTATTTTATGTGATTTTTGTCACAGATTTTTCTCTTAATATACCCTATCATTTACTATGTAAAAACAAATTTA
AGGAGGTAGTGGGCATGAAG

Downstream 100 bases:

>100_bases
TCAAACACCGGAGACAGTTCAGTGGTGTGAAAAAATTCTCCAGCAAACCTTAGGGATAGTTCTATTTGTTTGAAAACAAA
AAGCTCTCCATTTTCTGGAG

Product: hydroxylamine reductase

Products: NA

Alternate protein names: Hybrid-cluster protein; HCP

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MFCYQCQEALKNTGCTTIGVCGKTADVANLQDLLIFTLKGISFLNLKAREVGVNKEKTDRFLIEGLFSTITNVNFDRNFF
LRKIKEAVALRDEIKEDLRNKGVRVDEYKNIDAISWTYGTDADIEAISQEVGVLSTEDEDIRSLRELITYGVKGMAAYAY
HAYQLGYKDDNIFKFMEKALAKVLDDSLTVDDYVALAMETGKYGVDTMALLDKANTSTYGHPEITKVNIGVRNNPGILVS
GHDLKDLEQLLEQTAGTGVDVYTHGEMLPAHYYPAFKKYPHFVGNYGNAWWQQDKEFELFNGPILMTTNCLIPPKDSYKD
RVYTTGVVGFEGVKYIPEGPDGKKDFSEIIEHAKRCKPPVEIERGEIIGGFAHNQVLQLADKIVEAVKTGAIKRFFVMAG
CDGRMKSRTYYTEFAKALPKDTVILTAGCAKYRYNKLNLGDIDGIPRVLDAGQCNDSYSLAVIAMKLKEIFGLNDINELP
ISYNIAWYEQKAVIVLLALLYLGVKNIHLGPTLPAFLSPNVTKVLVEKFGIGGITNVEDDLKMFLGA

Sequences:

>Translated_547_residues
MFCYQCQEALKNTGCTTIGVCGKTADVANLQDLLIFTLKGISFLNLKAREVGVNKEKTDRFLIEGLFSTITNVNFDRNFF
LRKIKEAVALRDEIKEDLRNKGVRVDEYKNIDAISWTYGTDADIEAISQEVGVLSTEDEDIRSLRELITYGVKGMAAYAY
HAYQLGYKDDNIFKFMEKALAKVLDDSLTVDDYVALAMETGKYGVDTMALLDKANTSTYGHPEITKVNIGVRNNPGILVS
GHDLKDLEQLLEQTAGTGVDVYTHGEMLPAHYYPAFKKYPHFVGNYGNAWWQQDKEFELFNGPILMTTNCLIPPKDSYKD
RVYTTGVVGFEGVKYIPEGPDGKKDFSEIIEHAKRCKPPVEIERGEIIGGFAHNQVLQLADKIVEAVKTGAIKRFFVMAG
CDGRMKSRTYYTEFAKALPKDTVILTAGCAKYRYNKLNLGDIDGIPRVLDAGQCNDSYSLAVIAMKLKEIFGLNDINELP
ISYNIAWYEQKAVIVLLALLYLGVKNIHLGPTLPAFLSPNVTKVLVEKFGIGGITNVEDDLKMFLGA
>Mature_547_residues
MFCYQCQEALKNTGCTTIGVCGKTADVANLQDLLIFTLKGISFLNLKAREVGVNKEKTDRFLIEGLFSTITNVNFDRNFF
LRKIKEAVALRDEIKEDLRNKGVRVDEYKNIDAISWTYGTDADIEAISQEVGVLSTEDEDIRSLRELITYGVKGMAAYAY
HAYQLGYKDDNIFKFMEKALAKVLDDSLTVDDYVALAMETGKYGVDTMALLDKANTSTYGHPEITKVNIGVRNNPGILVS
GHDLKDLEQLLEQTAGTGVDVYTHGEMLPAHYYPAFKKYPHFVGNYGNAWWQQDKEFELFNGPILMTTNCLIPPKDSYKD
RVYTTGVVGFEGVKYIPEGPDGKKDFSEIIEHAKRCKPPVEIERGEIIGGFAHNQVLQLADKIVEAVKTGAIKRFFVMAG
CDGRMKSRTYYTEFAKALPKDTVILTAGCAKYRYNKLNLGDIDGIPRVLDAGQCNDSYSLAVIAMKLKEIFGLNDINELP
ISYNIAWYEQKAVIVLLALLYLGVKNIHLGPTLPAFLSPNVTKVLVEKFGIGGITNVEDDLKMFLGA

Specific function: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O

COG id: COG1151

COG function: function code C; 6Fe-6S prismane cluster-containing protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HCP family

Homologues:

Organism=Escherichia coli, GI87081794, Length=567, Percent_Identity=43.3862433862434, Blast_Score=460, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HCP_THETN (Q8R6M9)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_624272.2
- ProteinModelPortal:   Q8R6M9
- SMR:   Q8R6M9
- GeneID:   995617
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE2772
- NMPDR:   fig|273068.3.peg.2353
- HOGENOM:   HBG294215
- OMA:   ISERNIA
- ProtClustDB:   PRK05290
- BioCyc:   TTEN273068:TTE2772-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00069
- InterPro:   IPR010048
- InterPro:   IPR004137
- InterPro:   IPR011254
- InterPro:   IPR016099
- InterPro:   IPR016100
- Gene3D:   G3DSA:3.40.50.2030
- Gene3D:   G3DSA:1.20.1270.20
- PIRSF:   PIRSF000076
- TIGRFAMs:   TIGR01703

Pfam domain/function: PF03063 Prismane; SSF56821 Prismane_like

EC number: NA

Molecular weight: Translated: 61032; Mature: 61032

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFCYQCQEALKNTGCTTIGVCGKTADVANLQDLLIFTLKGISFLNLKAREVGVNKEKTDR
CCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEHHHCCCCHHHHHH
FLIEGLFSTITNVNFDRNFFLRKIKEAVALRDEIKEDLRNKGVRVDEYKNIDAISWTYGT
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCC
DADIEAISQEVGVLSTEDEDIRSLRELITYGVKGMAAYAYHAYQLGYKDDNIFKFMEKAL
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHEECCCCCCHHHHHHHHHH
AKVLDDSLTVDDYVALAMETGKYGVDTMALLDKANTSTYGHPEITKVNIGVRNNPGILVS
HHHHCCCCCHHHHHHEEEECCCCCCHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEEE
GHDLKDLEQLLEQTAGTGVDVYTHGEMLPAHYYPAFKKYPHFVGNYGNAWWQQDKEFELF
CCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCHHHHCCHHHCCCCCHHHCCCCCEEEE
NGPILMTTNCLIPPKDSYKDRVYTTGVVGFEGVKYIPEGPDGKKDFSEIIEHAKRCKPPV
CCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHCCCCC
EIERGEIIGGFAHNQVLQLADKIVEAVKTGAIKRFFVMAGCDGRMKSRTYYTEFAKALPK
EECCCCEEECHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHCCC
DTVILTAGCAKYRYNKLNLGDIDGIPRVLDAGQCNDSYSLAVIAMKLKEIFGLNDINELP
CEEEEEECHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
ISYNIAWYEQKAVIVLLALLYLGVKNIHLGPTLPAFLSPNVTKVLVEKFGIGGITNVEDD
EEEEEEEECCHHHHHHHHHHHHCCCCEECCCCCHHHHCCCHHHHHHHHHCCCCCCCCHHH
LKMFLGA
HHHHHCC
>Mature Secondary Structure
MFCYQCQEALKNTGCTTIGVCGKTADVANLQDLLIFTLKGISFLNLKAREVGVNKEKTDR
CCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEHHHCCCCHHHHHH
FLIEGLFSTITNVNFDRNFFLRKIKEAVALRDEIKEDLRNKGVRVDEYKNIDAISWTYGT
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCC
DADIEAISQEVGVLSTEDEDIRSLRELITYGVKGMAAYAYHAYQLGYKDDNIFKFMEKAL
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHEECCCCCCHHHHHHHHHH
AKVLDDSLTVDDYVALAMETGKYGVDTMALLDKANTSTYGHPEITKVNIGVRNNPGILVS
HHHHCCCCCHHHHHHEEEECCCCCCHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEEE
GHDLKDLEQLLEQTAGTGVDVYTHGEMLPAHYYPAFKKYPHFVGNYGNAWWQQDKEFELF
CCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCHHHHCCHHHCCCCCHHHCCCCCEEEE
NGPILMTTNCLIPPKDSYKDRVYTTGVVGFEGVKYIPEGPDGKKDFSEIIEHAKRCKPPV
CCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHCCCCC
EIERGEIIGGFAHNQVLQLADKIVEAVKTGAIKRFFVMAGCDGRMKSRTYYTEFAKALPK
EECCCCEEECHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHCCC
DTVILTAGCAKYRYNKLNLGDIDGIPRVLDAGQCNDSYSLAVIAMKLKEIFGLNDINELP
CEEEEEECHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
ISYNIAWYEQKAVIVLLALLYLGVKNIHLGPTLPAFLSPNVTKVLVEKFGIGGITNVEDD
EEEEEEEECCHHHHHHHHHHHHCCCCEECCCCCHHHHCCCHHHHHHHHHCCCCCCCCHHH
LKMFLGA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336