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The map label for this gene is atpA [H]

Identifier: 161723840

GI number: 161723840

Start: 1144035

End: 1145567

Strand: Reverse

Name: atpA [H]

Synonym: RC1237

Alternate gene names: 161723840

Gene position: 1145567-1144035 (Counterclockwise)

Preceding gene: 15893161

Following gene: 15893159

Centisome position: 90.29

GC content: 38.49

Gene sequence:

>1533_bases
ATGAAACTAAAGCCTATTGAAGTAGCTGAAATATTACAAAAGGAAATAGCTAATATTAATTGCTTAAGTGAGCTTGAGGA
AGTAGGGCAGGTAATAACCGTCGGTGACGGTATAGCCCAAATTTACGGTCTTGCTAATGTAAAATCCGGTGAAGTAGTAG
AATTTAAATCCGGTGTTAAGGGCCTTGTTTTAAACTTGGAAAACGATAGTGTTGGTGCTGTAATTATGGGGGATGATAAC
CAAGTACAGCAAGGTGATAATGTCAAAAGAACTAAAGCAGTTTTAGAAGTACCGGTAGGAAAAGCTTTGCTTGGTCGTGT
TGTTGATGCTCTAGGTAATCCTATTGACGGCAAAGGCGATATTGCAAGTAAAGAGTACAGACATATCGAGATGAAGGCTC
CGGGGATAATAGAAAGAACGAGCGTGAGTGAACCCGTACAAACCGGAATAAAGGCTATAGATTCGTTAATCCCAATAGGT
AGAGGACAAAGAGAGTTAATAATCGGTGATAGGCAAACTGGAAAAACGGCTATAGCCGTTGATACTATTATTAATCAAAA
ACAAGCTCATTCACTTACTAATGAAAGTGATAAAATTTATTGTATTTATGTAGCTATTGGGCAGAAAAGATCAAGTGTTG
CACAAATAGTAAAAAAACTAGAAGATGCCGGAGCCATGGACTATACACTTATTGTTTCGGCTACTGCTTCGGAAGCTGCA
GCTCTTCAATTCATTGCCCCTTATTCTGCCTGTAGTATGGGCGAATATTTTCGTGATAACGGCATGCACGCACTTATTAT
TTATGATGATTTAAGTAAGCATGCCGTTGCATATAGACAAATCTCATTATTACTTAGAAGACCTCCCGGGCGAGAAGCCT
ATCCCGGCGACGTGTTCTACCTGCATTCAAGGTTGCTTGAGCGTGCTGCTAAAATGTCAGAGGAAAAAGGCAGCGGTTCA
CTTACTGCTCTTCCTATAATCGAAACGCAGGCAGGTGACGTATCCGCATATATCCCAACAAATGTTATTTCGATTACCGA
CGGTCAAATTTTCTTAGAAAGTGAGCTATTTTATAAAGGCGTAAGACCTGCCGTTAATGTCGGTATTTCGGTAAGTCGTG
TTGGTTCTGCAGCACAAATAAAGGCTATGAAGCAGGTAGCAGGTTCGGTAAAGCTAGAGCTTGCTCAATTTAGAGAGCTT
GAGTCTTTCTCGCAATTTGGATCAGATTTAGACCCTGCCACTAAAGCACAAATCGATCACGGTAAAAGATTAGTTGAGAT
ATTAAAACAAGCTCAATATCATCCTTTTCCGGTAGAAGAACAAATAGTAAGTATTTATGTCGGAACTAAGAAATATTTAA
ATGATGTCCCGCTTCAGAAAGTAAAAGAATTTGAAGATAAAATGCTTACGGAGATAAGGTTAAATAAAAAAGATATTTTG
GAATCAATAAAAAACGAGCAACGTATAACCGAAGAAACCGAGCAGAAACTGAAAGCATTTTTAGAAAATTTCGTTAAGGA
ATTTGTTAAATAA

Upstream 100 bases:

>100_bases
AAGATTGCCATGAGGCCTACGGCTGCTCGCAATGACGACTCGGTATCCACACGGGCAATGCTCGTTCGCAATGACAAGAA
AATTAGGAGACATAAACCAC

Downstream 100 bases:

>100_bases
GATGATGTTGTTTTTGTGTGGATACTAAATCGTCATTGCGAGTGACTGAAAGGAGCGTGGCAATCTCAGGATATTTGATG
AGATTGCAACAAAGCTTCGT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MKLKPIEVAEILQKEIANINCLSELEEVGQVITVGDGIAQIYGLANVKSGEVVEFKSGVKGLVLNLENDSVGAVIMGDDN
QVQQGDNVKRTKAVLEVPVGKALLGRVVDALGNPIDGKGDIASKEYRHIEMKAPGIIERTSVSEPVQTGIKAIDSLIPIG
RGQRELIIGDRQTGKTAIAVDTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTLIVSATASEAA
ALQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEEKGSGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFYKGVRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFREL
ESFSQFGSDLDPATKAQIDHGKRLVEILKQAQYHPFPVEEQIVSIYVGTKKYLNDVPLQKVKEFEDKMLTEIRLNKKDIL
ESIKNEQRITEETEQKLKAFLENFVKEFVK

Sequences:

>Translated_510_residues
MKLKPIEVAEILQKEIANINCLSELEEVGQVITVGDGIAQIYGLANVKSGEVVEFKSGVKGLVLNLENDSVGAVIMGDDN
QVQQGDNVKRTKAVLEVPVGKALLGRVVDALGNPIDGKGDIASKEYRHIEMKAPGIIERTSVSEPVQTGIKAIDSLIPIG
RGQRELIIGDRQTGKTAIAVDTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTLIVSATASEAA
ALQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEEKGSGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFYKGVRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFREL
ESFSQFGSDLDPATKAQIDHGKRLVEILKQAQYHPFPVEEQIVSIYVGTKKYLNDVPLQKVKEFEDKMLTEIRLNKKDIL
ESIKNEQRITEETEQKLKAFLENFVKEFVK
>Mature_510_residues
MKLKPIEVAEILQKEIANINCLSELEEVGQVITVGDGIAQIYGLANVKSGEVVEFKSGVKGLVLNLENDSVGAVIMGDDN
QVQQGDNVKRTKAVLEVPVGKALLGRVVDALGNPIDGKGDIASKEYRHIEMKAPGIIERTSVSEPVQTGIKAIDSLIPIG
RGQRELIIGDRQTGKTAIAVDTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTLIVSATASEAA
ALQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEEKGSGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFYKGVRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFREL
ESFSQFGSDLDPATKAQIDHGKRLVEILKQAQYHPFPVEEQIVSIYVGTKKYLNDVPLQKVKEFEDKMLTEIRLNKKDIL
ESIKNEQRITEETEQKLKAFLENFVKEFVK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=502, Percent_Identity=65.3386454183267, Blast_Score=694, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=502, Percent_Identity=65.3386454183267, Blast_Score=694, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=337, Percent_Identity=28.486646884273, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI19913426, Length=336, Percent_Identity=27.0833333333333, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI32189394, Length=418, Percent_Identity=23.9234449760766, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI19913424, Length=255, Percent_Identity=26.6666666666667, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1790172, Length=515, Percent_Identity=56.3106796116505, Blast_Score=586, Evalue=1e-168,
Organism=Escherichia coli, GI1790170, Length=327, Percent_Identity=27.217125382263, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1788251, Length=346, Percent_Identity=27.4566473988439, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=65.3386454183267, Blast_Score=694, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=65.3386454183267, Blast_Score=692, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=61.1553784860558, Blast_Score=634, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17510931, Length=299, Percent_Identity=28.0936454849498, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=292, Percent_Identity=27.3972602739726, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=317, Percent_Identity=25.2365930599369, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=72, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71988068, Length=73, Percent_Identity=47.945205479452, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=26.3779527559055, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319370, Length=507, Percent_Identity=62.1301775147929, Blast_Score=667, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=298, Percent_Identity=29.5302013422819, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6322581, Length=406, Percent_Identity=25.1231527093596, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24658560, Length=502, Percent_Identity=65.3386454183267, Blast_Score=691, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=340, Percent_Identity=27.9411764705882, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24646341, Length=340, Percent_Identity=27.9411764705882, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136796, Length=340, Percent_Identity=27.9411764705882, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574560, Length=418, Percent_Identity=25.8373205741627, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24638766, Length=411, Percent_Identity=24.0875912408759, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=27.4509803921569, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=27.4509803921569, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=27.4509803921569, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583992, Length=255, Percent_Identity=27.4509803921569, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129479, Length=267, Percent_Identity=28.0898876404494, Blast_Score=76, Evalue=7e-14,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55992; Mature: 55992

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKPIEVAEILQKEIANINCLSELEEVGQVITVGDGIAQIYGLANVKSGEVVEFKSGVK
CCCCCHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCHHHHHHHCCCCCCCCEEEECCCCC
GLVLNLENDSVGAVIMGDDNQVQQGDNVKRTKAVLEVPVGKALLGRVVDALGNPIDGKGD
EEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
IASKEYRHIEMKAPGIIERTSVSEPVQTGIKAIDSLIPIGRGQRELIIGDRQTGKTAIAV
CCCCCCEEEEECCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEH
DTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTLIVSATASEAA
HHHHCHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHH
ALQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFY
HHHHCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LHSRLLERAAKMSEEKGSGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFYKG
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEECHHHHHC
VRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFRELESFSQFGSDLDPATKAQIDH
CCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GKRLVEILKQAQYHPFPVEEQIVSIYVGTKKYLNDVPLQKVKEFEDKMLTEIRLNKKDIL
HHHHHHHHHHCCCCCCCHHHHHEEEEECCHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHH
ESIKNEQRITEETEQKLKAFLENFVKEFVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLKPIEVAEILQKEIANINCLSELEEVGQVITVGDGIAQIYGLANVKSGEVVEFKSGVK
CCCCCHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCHHHHHHHCCCCCCCCEEEECCCCC
GLVLNLENDSVGAVIMGDDNQVQQGDNVKRTKAVLEVPVGKALLGRVVDALGNPIDGKGD
EEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
IASKEYRHIEMKAPGIIERTSVSEPVQTGIKAIDSLIPIGRGQRELIIGDRQTGKTAIAV
CCCCCCEEEEECCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEH
DTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTLIVSATASEAA
HHHHCHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHH
ALQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFY
HHHHCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LHSRLLERAAKMSEEKGSGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFYKG
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEECHHHHHC
VRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFRELESFSQFGSDLDPATKAQIDH
CCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GKRLVEILKQAQYHPFPVEEQIVSIYVGTKKYLNDVPLQKVKEFEDKMLTEIRLNKKDIL
HHHHHHHHHHCCCCCCCHHHHHEEEEECCHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHH
ESIKNEQRITEETEQKLKAFLENFVKEFVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA