Click here to switch to the map view.

The map label for this gene is argS [H]

Identifier: 161723314

GI number: 161723314

Start: 635328

End: 637061

Strand: Reverse

Name: argS [H]

Synonym: PM0551

Alternate gene names: 161723314

Gene position: 637061-635328 (Counterclockwise)

Preceding gene: 15602431

Following gene: 15602414

Centisome position: 28.22

GC content: 40.83

Gene sequence:

>1734_bases
GTGAATATTCAATCTATTTTATCTCATAAAATTCAACAAGCCATGATTGCTAGCGGTGCAGATACCCAATCTGATGCTTT
AGTTCGCCAATCAGCAAAAGTACAATTTGGTGACTATCAAGCTAATGGCATTATGGCGGCAGCGAAAAAGCTTGGACGTA
ATCCGCGTGAATTCGCACAACAAGTTATCGAACAACTTGATTTAAGCGAAATAGCTGAAAAAATCGAAATCGCGGGTCCT
GGTTTTATTAATCTTTTCTTAGATAAAAATTGGTTAGCTGAACAAATCAGCCTTGCCGTCAACGATGACAAACTCGGTAT
CCAAGCCACAGAAACACAAACCGTTGTTGCCGATTATTCCTCACCAAATGTTGCCAAAGAAATGCATGTGGGTCACTTAC
GCTCCACTATCATTGGTGATGCTGTCGTACGAACACTCGAATTTTTAGGTAATAAAGTGATTCGTGCTAACCATGTGGGT
GACTGGGGAACCCAATTCGGTATGTTGATTGCTTACCTAGAAAAAGTTGAAAATGAAAGTGCCAGTGAAATGGAACTGAG
CGATTTAGAAGCTTTCTATCGTGCGGCGAAAGAACATTATGACTCGGACCCCGTTTTTGCGGAAAAAGCGCGTAACTATG
TGGTGAAATTACAAAGTGGTGATGAATATTGTCGCACTATGTGGAAAAAATTAGTTGATATCACCATGCAACAGAATCAA
CACAATTATGACCGCTTAAATGTCACATTGACCGAAAAGGATGTCATGGGAGAAAGTTTATACAATCCCATGTTGTCCGA
TATCGTCGCGGATCTGAAACAACAAGGTCTTGCCGTTGAAGACGAAGGGGCATTCGTGGTTTACCTTGATGAGTTTAAAA
ATAAAGAAGGGGAACCAATGGGGGTGATTGTCCAGAAAAAAGATGGCGGATTTCTGTACACCACCACAGATATTGCGGCA
GCCAAATACCGCTATGAAACGTTAAAAGCGGATCGCGCACTGGTATTTTCAGATACACGTCAAAGCCAACATATGCAACA
GGCTTGGTTAATCACACGTAAAGCAGGTTATGTGCCAGACAGCTTCCAATTAGAACATAAAAACTTTGGGATGATGTTAG
GCAAAGACGGAAAGCCTTTCAAAACACGTACTGGGGGAACGGTAAAACTGGCAGATTTACTCGACGAAGCAGTTGAACGT
GCCACCCAATTAATTCAGGAAAAAAGCACCGCACTTTCCGCACAAGAAAAAGCGGCGGTCATTGAAGCGGTTGCGATTGG
TTCTGTCAAATATGCTGACCTCTCTAAAAATCGAACCACAGATTATGTGTTTGATTGGGATAATATGCTCAGCTTTGAAG
GGAATACCGCACCGTATATGCAATATGCCTATACACGTATTCGCTCTATCTTCAATCGTAGTGAACTAAATGAACAGGAT
CTTAGCGAAAGTCCTGTTGTGCTCAGCAATGAAAAAGAGCGCTTGTTGGCGATTAAATTGTTGCAATTTGAAGAAGCAAT
CCAAATTGTTGCCAAAGAAGGCACACCTCATGTGTTGTGTACCTATTTATATGAATTAGCAGGTGTCTTTTCTTCATTCT
ATGAACACTGCCCAATTCTGAATAATGAAGATGAACAAATTAAACGCAGTCGCTTAAAACTGGCATTATTAACAGAAAAA
ACCTTAAAACAAGGACTCGATTTGTTGGGTATTAAGACTGTTGATAAGATGTAA

Upstream 100 bases:

>100_bases
TTAAAAGTTATCATTTTTTCTCGCTTTATCTTTTCTGAATAAGGAAAGAACGGTATCATAACCGATTATTTTATTAATTG
TTATTCTTAGGTATAAAACG

Downstream 100 bases:

>100_bases
TCATCGAAGGCAATCACAAAAGCTGATAGAAATATCAGCTTTTTTTGAAACAAAAAAAAGTGCCTTGAAACAAGGCACTA
CTCGGAAAGCAAAATATGTC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNIQSILSHKIQQAMIASGADTQSDALVRQSAKVQFGDYQANGIMAAAKKLGRNPREFAQQVIEQLDLSEIAEKIEIAGP
GFINLFLDKNWLAEQISLAVNDDKLGIQATETQTVVADYSSPNVAKEMHVGHLRSTIIGDAVVRTLEFLGNKVIRANHVG
DWGTQFGMLIAYLEKVENESASEMELSDLEAFYRAAKEHYDSDPVFAEKARNYVVKLQSGDEYCRTMWKKLVDITMQQNQ
HNYDRLNVTLTEKDVMGESLYNPMLSDIVADLKQQGLAVEDEGAFVVYLDEFKNKEGEPMGVIVQKKDGGFLYTTTDIAA
AKYRYETLKADRALVFSDTRQSQHMQQAWLITRKAGYVPDSFQLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAVER
ATQLIQEKSTALSAQEKAAVIEAVAIGSVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNRSELNEQD
LSESPVVLSNEKERLLAIKLLQFEEAIQIVAKEGTPHVLCTYLYELAGVFSSFYEHCPILNNEDEQIKRSRLKLALLTEK
TLKQGLDLLGIKTVDKM

Sequences:

>Translated_577_residues
MNIQSILSHKIQQAMIASGADTQSDALVRQSAKVQFGDYQANGIMAAAKKLGRNPREFAQQVIEQLDLSEIAEKIEIAGP
GFINLFLDKNWLAEQISLAVNDDKLGIQATETQTVVADYSSPNVAKEMHVGHLRSTIIGDAVVRTLEFLGNKVIRANHVG
DWGTQFGMLIAYLEKVENESASEMELSDLEAFYRAAKEHYDSDPVFAEKARNYVVKLQSGDEYCRTMWKKLVDITMQQNQ
HNYDRLNVTLTEKDVMGESLYNPMLSDIVADLKQQGLAVEDEGAFVVYLDEFKNKEGEPMGVIVQKKDGGFLYTTTDIAA
AKYRYETLKADRALVFSDTRQSQHMQQAWLITRKAGYVPDSFQLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAVER
ATQLIQEKSTALSAQEKAAVIEAVAIGSVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNRSELNEQD
LSESPVVLSNEKERLLAIKLLQFEEAIQIVAKEGTPHVLCTYLYELAGVFSSFYEHCPILNNEDEQIKRSRLKLALLTEK
TLKQGLDLLGIKTVDKM
>Mature_577_residues
MNIQSILSHKIQQAMIASGADTQSDALVRQSAKVQFGDYQANGIMAAAKKLGRNPREFAQQVIEQLDLSEIAEKIEIAGP
GFINLFLDKNWLAEQISLAVNDDKLGIQATETQTVVADYSSPNVAKEMHVGHLRSTIIGDAVVRTLEFLGNKVIRANHVG
DWGTQFGMLIAYLEKVENESASEMELSDLEAFYRAAKEHYDSDPVFAEKARNYVVKLQSGDEYCRTMWKKLVDITMQQNQ
HNYDRLNVTLTEKDVMGESLYNPMLSDIVADLKQQGLAVEDEGAFVVYLDEFKNKEGEPMGVIVQKKDGGFLYTTTDIAA
AKYRYETLKADRALVFSDTRQSQHMQQAWLITRKAGYVPDSFQLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAVER
ATQLIQEKSTALSAQEKAAVIEAVAIGSVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNRSELNEQD
LSESPVVLSNEKERLLAIKLLQFEEAIQIVAKEGTPHVLCTYLYELAGVFSSFYEHCPILNNEDEQIKRSRLKLALLTEK
TLKQGLDLLGIKTVDKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=600, Percent_Identity=39.5, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI197100773, Length=537, Percent_Identity=28.3054003724395, Blast_Score=195, Evalue=1e-49,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=71.2305025996534, Blast_Score=880, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=595, Percent_Identity=39.4957983193277, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71985068, Length=563, Percent_Identity=40.3197158081705, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17532153, Length=498, Percent_Identity=25.1004016064257, Blast_Score=147, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320548, Length=545, Percent_Identity=33.7614678899083, Blast_Score=260, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6321883, Length=551, Percent_Identity=29.2196007259528, Blast_Score=220, Evalue=5e-58,
Organism=Drosophila melanogaster, GI18859963, Length=566, Percent_Identity=38.86925795053, Blast_Score=390, Evalue=1e-108,
Organism=Drosophila melanogaster, GI28571570, Length=545, Percent_Identity=28.6238532110092, Blast_Score=177, Evalue=3e-44,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64926; Mature: 64926

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQSILSHKIQQAMIASGADTQSDALVRQSAKVQFGDYQANGIMAAAKKLGRNPREFAQ
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEECCCCCCHHHHHHHHHCCCHHHHHH
QVIEQLDLSEIAEKIEIAGPGFINLFLDKNWLAEQISLAVNDDKLGIQATETQTVVADYS
HHHHHCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHEEEECCCCCCEEECCCEEEEEECC
SPNVAKEMHVGHLRSTIIGDAVVRTLEFLGNKVIRANHVGDWGTQFGMLIAYLEKVENES
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCC
ASEMELSDLEAFYRAAKEHYDSDPVFAEKARNYVVKLQSGDEYCRTMWKKLVDITMQQNQ
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
HNYDRLNVTLTEKDVMGESLYNPMLSDIVADLKQQGLAVEDEGAFVVYLDEFKNKEGEPM
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEHHCCCCCCCE
GVIVQKKDGGFLYTTTDIAAAKYRYETLKADRALVFSDTRQSQHMQQAWLITRKAGYVPD
EEEEEECCCCEEEEECHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCC
SFQLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAVERATQLIQEKSTALSAQEKAAV
CEEECCCCCCEEECCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEAVAIGSVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNRSELNEQD
HHHHHHCCEEEECCCCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHC
LSESPVVLSNEKERLLAIKLLQFEEAIQIVAKEGTPHVLCTYLYELAGVFSSFYEHCPIL
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NNEDEQIKRSRLKLALLTEKTLKQGLDLLGIKTVDKM
CCCHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHCCC
>Mature Secondary Structure
MNIQSILSHKIQQAMIASGADTQSDALVRQSAKVQFGDYQANGIMAAAKKLGRNPREFAQ
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEECCCCCCHHHHHHHHHCCCHHHHHH
QVIEQLDLSEIAEKIEIAGPGFINLFLDKNWLAEQISLAVNDDKLGIQATETQTVVADYS
HHHHHCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHEEEECCCCCCEEECCCEEEEEECC
SPNVAKEMHVGHLRSTIIGDAVVRTLEFLGNKVIRANHVGDWGTQFGMLIAYLEKVENES
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCC
ASEMELSDLEAFYRAAKEHYDSDPVFAEKARNYVVKLQSGDEYCRTMWKKLVDITMQQNQ
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
HNYDRLNVTLTEKDVMGESLYNPMLSDIVADLKQQGLAVEDEGAFVVYLDEFKNKEGEPM
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEHHCCCCCCCE
GVIVQKKDGGFLYTTTDIAAAKYRYETLKADRALVFSDTRQSQHMQQAWLITRKAGYVPD
EEEEEECCCCEEEEECHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCC
SFQLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAVERATQLIQEKSTALSAQEKAAV
CEEECCCCCCEEECCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEAVAIGSVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNRSELNEQD
HHHHHHCCEEEECCCCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHC
LSESPVVLSNEKERLLAIKLLQFEEAIQIVAKEGTPHVLCTYLYELAGVFSSFYEHCPIL
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NNEDEQIKRSRLKLALLTEKTLKQGLDLLGIKTVDKM
CCCHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]