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The map label for this gene is hemN-1 [H]

Identifier: 161723176

GI number: 161723176

Start: 1707741

End: 1709135

Strand: Reverse

Name: hemN-1 [H]

Synonym: BTH_I1509

Alternate gene names: 161723176

Gene position: 1709135-1707741 (Counterclockwise)

Preceding gene: 83718399

Following gene: 83719328

Centisome position: 44.87

GC content: 67.46

Gene sequence:

>1395_bases
ATGACGCAGCCGATTCCGTCCGAGGCGCTGTTTCGCCCCGATCTGCTCGCCAAGTACACGGCGAACGGCCCTCGCTATAC
GTCCTACCCCACCGCCCCTCAGTTCCGCGAAAATTTCGATCCCGCCGACTACATCCGCGCGGCGGCCGACCCGGGCGCGT
CCGCCAGCGATCTGTCACTCTATTTCCACATCCCGTTCTGCGCGACCGCGTGCTTCTACTGCGGCTGCAACAAGATCGCG
ACGCGCAACCGCAAGCGCGCGCGGCCGTATCTCGATCAGTTGAAGCACGAGATCGCGTTGCAGGCCGCGCTCTTCGATCC
GGAGCGGACCGTCACGCAGCTCCACTGGGGCGGCGGCACGCCGACCTTCCTGTCGCAGGCCGAGACGACCGAACTGATGG
CGGCCACGCGCGAGTACTTCACGCTTGCGTCGGATCGCACCGGGGAATTCTCGATCGAGATCGATCCGCGCGCCGCGTCG
CCCGCGACGCTCGTCCATCTGCGCACGATCGGCTTCAATCGCGTGAGCCTCGGCGTGCAGGACTTCGACCCCGACGTGCA
ACGCGCGATCAACCGCGTGCAGCCGCTCAAGATGACGTCCGACCTCGTGCGCGCCGCGCGCGCAACGGGCTATCACTCGA
TCGGCATCGATCTCATCTACGGGCTGCCGCACCAGACGGTATCAAGCTTCGCGCGCACGCTCGACACGGTCGTCGAGCTC
GAGCCCGACCGGCTCTCCGTGTTCGGCTACGCGCACATGCCGCATCTGTTCAAGATGCAGCGCCAGATCGACGCCGCCGC
GCTGCCGCCCCCCGCGACACGCATCGCGCTGCTCGGCCTCGCGATCGAGCAGCTCACCCGCGCGGGCTACGTGTACATCG
GCATGGACCATTTCGCGCGGCCGGACGACGAGCTCGTGCGCGCGCAACGCAACGGCACGCTGCAGCGCAACTTCCAGGGC
TACAGCACGCGCGCGGACGCCGACCTGATCGGCATCGGCGCGTCGTCGATCGGCAAGGTCGGCGACGTCTACGCGCAGAA
CGCGAAGGACTTGCCGCGCTACGGCGCGGCGCTCGCCGACCAGCGGCTGCCGATCGTGCGCGGCGTGAAGCTCTCGGCGG
ACGACCGGCTGCGGCGCGACGTGATCACGCACCTGATGTGCAACCTCGTGCTGCCGTTCTCGCACGTCGAGGCCGCGTAC
GGCATCCGCTTCGCGAACAAGTTCTCGAGCGAGCTCGACACGCTGCGCGGCTTCGAGCGCGACGGCCTGCTGTCGATCGG
CGCAGATCGTCTGACGATTCATCCGGCCGGGCGTCTCCACGTGCGCAACATCGCGATGGTGTTCGACGCGTATCTGTCGG
GCGCATCCGAAAACCGCTACTCGAAGACCGTCTGA

Upstream 100 bases:

>100_bases
GTATTGTGCCATTCGCCGCTGCGACGTTATTACACAATTCAATGAAACCGACGGTTCCTATACTGGTCGACGTCATAGAG
CACGACTTCGAGCTTCCAGC

Downstream 100 bases:

>100_bases
GCGCGGCCGCGCCGCGCGCTCGGCGCGCGTTGTTGATAAAGTGGCGGTTTCATCGCACTTTCGTTTTTGACGCACGATGC
GCACCACGCAAGCGACCCGC

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTQPIPSEALFRPDLLAKYTANGPRYTSYPTAPQFRENFDPADYIRAAADPGASASDLSLYFHIPFCATACFYCGCNKIA
TRNRKRARPYLDQLKHEIALQAALFDPERTVTQLHWGGGTPTFLSQAETTELMAATREYFTLASDRTGEFSIEIDPRAAS
PATLVHLRTIGFNRVSLGVQDFDPDVQRAINRVQPLKMTSDLVRAARATGYHSIGIDLIYGLPHQTVSSFARTLDTVVEL
EPDRLSVFGYAHMPHLFKMQRQIDAAALPPPATRIALLGLAIEQLTRAGYVYIGMDHFARPDDELVRAQRNGTLQRNFQG
YSTRADADLIGIGASSIGKVGDVYAQNAKDLPRYGAALADQRLPIVRGVKLSADDRLRRDVITHLMCNLVLPFSHVEAAY
GIRFANKFSSELDTLRGFERDGLLSIGADRLTIHPAGRLHVRNIAMVFDAYLSGASENRYSKTV

Sequences:

>Translated_464_residues
MTQPIPSEALFRPDLLAKYTANGPRYTSYPTAPQFRENFDPADYIRAAADPGASASDLSLYFHIPFCATACFYCGCNKIA
TRNRKRARPYLDQLKHEIALQAALFDPERTVTQLHWGGGTPTFLSQAETTELMAATREYFTLASDRTGEFSIEIDPRAAS
PATLVHLRTIGFNRVSLGVQDFDPDVQRAINRVQPLKMTSDLVRAARATGYHSIGIDLIYGLPHQTVSSFARTLDTVVEL
EPDRLSVFGYAHMPHLFKMQRQIDAAALPPPATRIALLGLAIEQLTRAGYVYIGMDHFARPDDELVRAQRNGTLQRNFQG
YSTRADADLIGIGASSIGKVGDVYAQNAKDLPRYGAALADQRLPIVRGVKLSADDRLRRDVITHLMCNLVLPFSHVEAAY
GIRFANKFSSELDTLRGFERDGLLSIGADRLTIHPAGRLHVRNIAMVFDAYLSGASENRYSKTV
>Mature_463_residues
TQPIPSEALFRPDLLAKYTANGPRYTSYPTAPQFRENFDPADYIRAAADPGASASDLSLYFHIPFCATACFYCGCNKIAT
RNRKRARPYLDQLKHEIALQAALFDPERTVTQLHWGGGTPTFLSQAETTELMAATREYFTLASDRTGEFSIEIDPRAASP
ATLVHLRTIGFNRVSLGVQDFDPDVQRAINRVQPLKMTSDLVRAARATGYHSIGIDLIYGLPHQTVSSFARTLDTVVELE
PDRLSVFGYAHMPHLFKMQRQIDAAALPPPATRIALLGLAIEQLTRAGYVYIGMDHFARPDDELVRAQRNGTLQRNFQGY
STRADADLIGIGASSIGKVGDVYAQNAKDLPRYGAALADQRLPIVRGVKLSADDRLRRDVITHLMCNLVLPFSHVEAAYG
IRFANKFSSELDTLRGFERDGLLSIGADRLTIHPAGRLHVRNIAMVFDAYLSGASENRYSKTV

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=294, Percent_Identity=24.8299319727891, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI87082341, Length=451, Percent_Identity=48.5587583148559, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1789325, Length=283, Percent_Identity=28.2685512367491, Blast_Score=104, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004558
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 51411; Mature: 51280

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPIPSEALFRPDLLAKYTANGPRYTSYPTAPQFRENFDPADYIRAAADPGASASDLSL
CCCCCCCHHCCCCHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHHHHCCCCCCCCCCEEE
YFHIPFCATACFYCGCNKIATRNRKRARPYLDQLKHEIALQAALFDPERTVTQLHWGGGT
EEECHHHHHHHHHHCCCHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
PTFLSQAETTELMAATREYFTLASDRTGEFSIEIDPRAASPATLVHLRTIGFNRVSLGVQ
CHHHCCHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCCEEEEEEEECCCCEEECCHH
DFDPDVQRAINRVQPLKMTSDLVRAARATGYHSIGIDLIYGLPHQTVSSFARTLDTVVEL
CCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEECEEEEECCCHHHHHHHHHHHHHHHCC
EPDRLSVFGYAHMPHLFKMQRQIDAAALPPPATRIALLGLAIEQLTRAGYVYIGMDHFAR
CCCCEEEEEEHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEECHHCCC
PDDELVRAQRNGTLQRNFQGYSTRADADLIGIGASSIGKVGDVYAQNAKDLPRYGAALAD
CHHHHHHHHHCCCEEECCCCCCCCCCCCEEECCHHHHCHHHHHHHCCCCCCHHHHHHHHH
QRLPIVRGVKLSADDRLRRDVITHLMCNLVLPFSHVEAAYGIRFANKFSSELDTLRGFER
CCCCHHCCCEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DGLLSIGADRLTIHPAGRLHVRNIAMVFDAYLSGASENRYSKTV
CCCEEECCCEEEECCCCCEEHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TQPIPSEALFRPDLLAKYTANGPRYTSYPTAPQFRENFDPADYIRAAADPGASASDLSL
CCCCCCHHCCCCHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHHHHCCCCCCCCCCEEE
YFHIPFCATACFYCGCNKIATRNRKRARPYLDQLKHEIALQAALFDPERTVTQLHWGGGT
EEECHHHHHHHHHHCCCHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
PTFLSQAETTELMAATREYFTLASDRTGEFSIEIDPRAASPATLVHLRTIGFNRVSLGVQ
CHHHCCHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCCEEEEEEEECCCCEEECCHH
DFDPDVQRAINRVQPLKMTSDLVRAARATGYHSIGIDLIYGLPHQTVSSFARTLDTVVEL
CCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEECEEEEECCCHHHHHHHHHHHHHHHCC
EPDRLSVFGYAHMPHLFKMQRQIDAAALPPPATRIALLGLAIEQLTRAGYVYIGMDHFAR
CCCCEEEEEEHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEECHHCCC
PDDELVRAQRNGTLQRNFQGYSTRADADLIGIGASSIGKVGDVYAQNAKDLPRYGAALAD
CHHHHHHHHHCCCEEECCCCCCCCCCCCEEECCHHHHCHHHHHHHCCCCCCHHHHHHHHH
QRLPIVRGVKLSADDRLRRDVITHLMCNLVLPFSHVEAAYGIRFANKFSSELDTLRGFER
CCCCHHCCCEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DGLLSIGADRLTIHPAGRLHVRNIAMVFDAYLSGASENRYSKTV
CCCEEECCCEEEECCCCCEEHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9396835 [H]