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The map label for this gene is hscB

Identifier: 161702957

GI number: 161702957

Start: 2499314

End: 2499841

Strand: Reverse

Name: hscB

Synonym: Bcep18194_A5429

Alternate gene names: 161702957

Gene position: 2499841-2499314 (Counterclockwise)

Preceding gene: 78066899

Following gene: 78066897

Centisome position: 67.67

GC content: 68.18

Gene sequence:

>528_bases
ATGGTCTCGCTGAAAGACAGCCACTTCGACCTGTTTCACCTGCCGGCGCAATTCGCGCTCGACGAGACGGTGCTCGACGC
CGCTTACCGAACGGTGCAGACGCAGGTGCACCCGGACCGCTTCGCGGCGGCCGGCGACGCGCAGAAGCGCATCGCGATGC
AATGGGCCACCCGCGCGAACGAGGCGTATCGCACGCTGCGGGATCCTCTGAAGCGCGCGTCGTATCTGCTGTCGCTGCGC
GGCGTCGATATCGGCGCGGAAAACAACACCGCGATGGAGCCTGCGTTCCTGATGCAGCAGATGGAGTGGCGCGAGGGCAT
CGAGGATGCCGCGGCCGCCCGCAACGTCGACGCGCTCGACGCGCTGCTCGCCGAGTTGCGCGAAGAGCGGCGCGTGCGGG
TGGAGCGCCTCGGCACGCTGCTTGACAGCGGCGCCGATCAGGCGGCCGCCGAGGCCGTGCGCCAGCTGATGTTCATCGAA
CGGGTCGCGTCGGAAGTGGGCGCGCAGATCGAGCGCCTCGAAACTTAA

Upstream 100 bases:

>100_bases
TGACCACGCGGATCTCCGCGCGATGCGGGCAAGAGGCGGCACGGGCCGCCTTTTTAATGTGCGGCGTTTGCCGCGCGACG
AACCGGAATTGAACGCGACG

Downstream 100 bases:

>100_bases
CCGCGTGCCTTGCGGCACGCGCAGCAAACGGGCCGAGCGCCCGAACGAACCAAGATGGCTTTACTGCAAATTTCCGAACC
GGGCATGGCGCCGGCGCCGC

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MVSLKDSHFDLFHLPAQFALDETVLDAAYRTVQTQVHPDRFAAAGDAQKRIAMQWATRANEAYRTLRDPLKRASYLLSLR
GVDIGAENNTAMEPAFLMQQMEWREGIEDAAAARNVDALDALLAELREERRVRVERLGTLLDSGADQAAAEAVRQLMFIE
RVASEVGAQIERLET

Sequences:

>Translated_175_residues
MVSLKDSHFDLFHLPAQFALDETVLDAAYRTVQTQVHPDRFAAAGDAQKRIAMQWATRANEAYRTLRDPLKRASYLLSLR
GVDIGAENNTAMEPAFLMQQMEWREGIEDAAAARNVDALDALLAELREERRVRVERLGTLLDSGADQAAAEAVRQLMFIE
RVASEVGAQIERLET
>Mature_175_residues
MVSLKDSHFDLFHLPAQFALDETVLDAAYRTVQTQVHPDRFAAAGDAQKRIAMQWATRANEAYRTLRDPLKRASYLLSLR
GVDIGAENNTAMEPAFLMQQMEWREGIEDAAAARNVDALDALLAELREERRVRVERLGTLLDSGADQAAAEAVRQLMFIE
RVASEVGAQIERLET

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=115, Percent_Identity=32.1739130434783, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1788876, Length=166, Percent_Identity=36.144578313253, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17541320, Length=145, Percent_Identity=26.8965517241379, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161084223, Length=168, Percent_Identity=29.7619047619048, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 19628; Mature: 19628

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLKDSHFDLFHLPAQFALDETVLDAAYRTVQTQVHPDRFAAAGDAQKRIAMQWATRAN
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHH
EAYRTLRDPLKRASYLLSLRGVDIGAENNTAMEPAFLMQQMEWREGIEDAAAARNVDALD
HHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCHHHHH
ALLAELREERRVRVERLGTLLDSGADQAAAEAVRQLMFIERVASEVGAQIERLET
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSLKDSHFDLFHLPAQFALDETVLDAAYRTVQTQVHPDRFAAAGDAQKRIAMQWATRAN
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHH
EAYRTLRDPLKRASYLLSLRGVDIGAENNTAMEPAFLMQQMEWREGIEDAAAARNVDALD
HHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCHHHHH
ALLAELREERRVRVERLGTLLDSGADQAAAEAVRQLMFIERVASEVGAQIERLET
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA