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The map label for this gene is ureE

Identifier: 161546633

GI number: 161546633

Start: 394859

End: 395383

Strand: Direct

Name: ureE

Synonym: HH0410

Alternate gene names: 161546633

Gene position: 394859-395383 (Clockwise)

Preceding gene: 32265908

Following gene: 32265910

Centisome position: 21.95

GC content: 33.71

Gene sequence:

>525_bases
ATGCGAGTAGAACACATTATTGGTAATATCAAAGACATAGATGCGACGCATTTAGACATTGATGAAGTGCAAATAGCTTG
GTATGACACAAAGAAAAAAATTGCGCGTTTGAACTCACAAAATGGGCAAGTTATAGCAATGAAGCTTGCCCAAGCACCAA
AATATGGTTTAAATAATGGAGATATTCTTTTTCTAGATGAACACAAAATAATTATTATCTCTATTTTACCCACTTGGGTG
CTTTGTATGAAGCCGACACATTGGCATACTATGGCAAGATTATGTTATGAGATTGGAAATTTACATATACCACTCTTTTA
CAATAAAGACACAATGAAACTTCAAGCGCCATTTGAGCAACCACTGCAAAGAATCCTTGAAAAGCAATCTATCGCATTTG
AAAAAAAATGGTGTGTGCTAGATTCAAAAGATAGAATTAATATTACCTACCCTATTGCAAGTGAGCCAAAACTTATTCAA
AGCCCACATTTTTCTATCAAAATTACCCAAAAAGGATTAAATTGA

Upstream 100 bases:

>100_bases
TAAAAATTGAACTCAAATTTGTGCCTTATTTAGCCATTGCCGAGGGAATCCTCACCGCGTGGATTCCAGCGTGGCTTATC
CTTATGGGATATTGGCATTA

Downstream 100 bases:

>100_bases
ATTTTTTACTTTTACAAATCAATGATGCGCTTTTTCCCATAGGCAATTATACACATTCTTTTGGGCTAGAAAGCTATGTG
CAATTAGGCAGAATAAAAAA

Product: urease accessory protein UreE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MRVEHIIGNIKDIDATHLDIDEVQIAWYDTKKKIARLNSQNGQVIAMKLAQAPKYGLNNGDILFLDEHKIIIISILPTWV
LCMKPTHWHTMARLCYEIGNLHIPLFYNKDTMKLQAPFEQPLQRILEKQSIAFEKKWCVLDSKDRINITYPIASEPKLIQ
SPHFSIKITQKGLN

Sequences:

>Translated_174_residues
MRVEHIIGNIKDIDATHLDIDEVQIAWYDTKKKIARLNSQNGQVIAMKLAQAPKYGLNNGDILFLDEHKIIIISILPTWV
LCMKPTHWHTMARLCYEIGNLHIPLFYNKDTMKLQAPFEQPLQRILEKQSIAFEKKWCVLDSKDRINITYPIASEPKLIQ
SPHFSIKITQKGLN
>Mature_174_residues
MRVEHIIGNIKDIDATHLDIDEVQIAWYDTKKKIARLNSQNGQVIAMKLAQAPKYGLNNGDILFLDEHKIIIISILPTWV
LCMKPTHWHTMARLCYEIGNLHIPLFYNKDTMKLQAPFEQPLQRILEKQSIAFEKKWCVLDSKDRINITYPIASEPKLIQ
SPHFSIKITQKGLN

Specific function: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly

COG id: COG2371

COG function: function code O; Urease accessory protein UreE

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREE_HELHP (Q7VJ36)

Other databases:

- EMBL:   AF332656
- EMBL:   AE017125
- RefSeq:   NP_859941.2
- ProteinModelPortal:   Q7VJ36
- SMR:   Q7VJ36
- GeneID:   1493464
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0410
- NMPDR:   fig|235279.1.peg.410
- HOGENOM:   HBG501812
- OMA:   ICYEIGN
- ProtClustDB:   PRK13261
- BioCyc:   HHEP235279:HH_0410-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00822
- InterPro:   IPR012406
- InterPro:   IPR007864
- InterPro:   IPR004029
- Gene3D:   G3DSA:3.30.70.790
- PIRSF:   PIRSF036402

Pfam domain/function: PF05194 UreE_C; PF02814 UreE_N; SSF69737 UreE_C; SSF69287 UreE_N

EC number: NA

Molecular weight: Translated: 20173; Mature: 20173

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVEHIIGNIKDIDATHLDIDEVQIAWYDTKKKIARLNSQNGQVIAMKLAQAPKYGLNNG
CCCHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
DILFLDEHKIIIISILPTWVLCMKPTHWHTMARLCYEIGNLHIPLFYNKDTMKLQAPFEQ
CEEEECCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCEEEECCHHH
PLQRILEKQSIAFEKKWCVLDSKDRINITYPIASEPKLIQSPHFSIKITQKGLN
HHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCCCCCEECCCCEEEEEEECCCC
>Mature Secondary Structure
MRVEHIIGNIKDIDATHLDIDEVQIAWYDTKKKIARLNSQNGQVIAMKLAQAPKYGLNNG
CCCHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
DILFLDEHKIIIISILPTWVLCMKPTHWHTMARLCYEIGNLHIPLFYNKDTMKLQAPFEQ
CEEEECCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCEEEECCHHH
PLQRILEKQSIAFEKKWCVLDSKDRINITYPIASEPKLIQSPHFSIKITQKGLN
HHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCCCCCEECCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11500473; 12810954