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The map label for this gene is phnW2 [H]

Identifier: 161526307

GI number: 161526307

Start: 3429270

End: 3430400

Strand: Direct

Name: phnW2 [H]

Synonym: Bmul_3138

Alternate gene names: 161526307

Gene position: 3429270-3430400 (Clockwise)

Preceding gene: 161526306

Following gene: 161526308

Centisome position: 99.44

GC content: 67.9

Gene sequence:

>1131_bases
ATGACGCTCGCCGATCAGCCCATCCTGCTCACGCCCGGCCCTCTGACGACCTCCGCGCGCACGCGCGACGCGATGCTGCG
CGACTGGGGTTCGTGGGACAGCGACTTCAACGCGATCACGGCGCGGCTGCGCACGCGTCTCGTGCAGATCGTGCACGGCG
AAGAGACGCACGAATGCGTGCCGCTCCAAGGCAGCGGCACGTTCTCGGTCGAAGCGGCGATCGGCACGCTCGTGCCGCGC
GACGGCCACGTGCTGGTGCCGAACAACGGCGCGTACTGCCAGCGCATCGCGAAGATCTGCCGCGTGCTCGGCCGCCGGCT
GACGACGATCGACTACAGCGAAGACCGCCGCGTCGATCCGGCCGACATCGATCGCGCGCTCGCCGCCGATCCCGGCATCA
CGCACGTCGCGCTCGTGCACTGCGAGACGGGCACCGGCGTGATGAATCCGCTGCACGAGGTCGCGCAGGTCGTCGCGAAG
CACGGCCGCGGGCTGATCGTCGACGCGATGAGCTCGTTCGGCGCGATCGAGATCGACGCGCGCACGACGCCGTTCGACGC
GGTGATTGCGGCATCGGGCAAGTGTCTCGAAGGCGTGCCGGGCATCGGCTTCGTGATCGCGAAGCGCAGCACGCTCGAAC
GTTGCGAAGGCAACTGCCATTCGCTCGCGATGGACCTGTACGACCAGTGGGTCTACATGCAGCGCACGACGCAGTGGCGC
TTCACGCCGCCGACGCACGTCGTCGCGGCACTCGATGCGGCGCTCGCGCAATACCTCGACGAAGGCGGGCTCGCTGCACG
CGGCGGCCGCTATCAGCGCAACTATCGTGCGCTGATCGACGGGATGCGCGCGCTCGGCTTCCGCCCGTTCCTCGATCCGG
CGATCCAGGCGCCGATCATCGTCACGTTCCATGCGCCGGACGATCCGAACTACGACTTCAAGACCTTTTATCAAGAGGTC
AAAAAGCGCGGCTACATTCTGTATCCGGGCAAGCTCACGCAGGTCGAGACGTTCCGCGTCGGCTGCATCGGCCACTTCGG
CGAAGCGGGCATTCCGGGCGCCGTCGCCGCGATCGCCGACACGCTGAAGGCGATGGGCGTGCAGCGCATGTCCGCCGAAG
CCGCCGCGTGA

Upstream 100 bases:

>100_bases
TCGCACGTGCTGCTGCGTCGCACGCAGGCATGGCGCACGCCGTATCGCCGCTGATTTCCCGATGCACCGATCCGATGCCC
GACTTCCTCAAGGAGACACC

Downstream 100 bases:

>100_bases
TGCGCGCCACACCGGCACCGTTCGGGCCGCGCACGCGCGCGGCCCTTCACTCAATCGACTGAACCCTCGATGCGACCTTT
CTGGATCGAACAAGCGCTGT

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase 2; AEP transaminase 2; AEPT 2 [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MTLADQPILLTPGPLTTSARTRDAMLRDWGSWDSDFNAITARLRTRLVQIVHGEETHECVPLQGSGTFSVEAAIGTLVPR
DGHVLVPNNGAYCQRIAKICRVLGRRLTTIDYSEDRRVDPADIDRALAADPGITHVALVHCETGTGVMNPLHEVAQVVAK
HGRGLIVDAMSSFGAIEIDARTTPFDAVIAASGKCLEGVPGIGFVIAKRSTLERCEGNCHSLAMDLYDQWVYMQRTTQWR
FTPPTHVVAALDAALAQYLDEGGLAARGGRYQRNYRALIDGMRALGFRPFLDPAIQAPIIVTFHAPDDPNYDFKTFYQEV
KKRGYILYPGKLTQVETFRVGCIGHFGEAGIPGAVAAIADTLKAMGVQRMSAEAAA

Sequences:

>Translated_376_residues
MTLADQPILLTPGPLTTSARTRDAMLRDWGSWDSDFNAITARLRTRLVQIVHGEETHECVPLQGSGTFSVEAAIGTLVPR
DGHVLVPNNGAYCQRIAKICRVLGRRLTTIDYSEDRRVDPADIDRALAADPGITHVALVHCETGTGVMNPLHEVAQVVAK
HGRGLIVDAMSSFGAIEIDARTTPFDAVIAASGKCLEGVPGIGFVIAKRSTLERCEGNCHSLAMDLYDQWVYMQRTTQWR
FTPPTHVVAALDAALAQYLDEGGLAARGGRYQRNYRALIDGMRALGFRPFLDPAIQAPIIVTFHAPDDPNYDFKTFYQEV
KKRGYILYPGKLTQVETFRVGCIGHFGEAGIPGAVAAIADTLKAMGVQRMSAEAAA
>Mature_375_residues
TLADQPILLTPGPLTTSARTRDAMLRDWGSWDSDFNAITARLRTRLVQIVHGEETHECVPLQGSGTFSVEAAIGTLVPRD
GHVLVPNNGAYCQRIAKICRVLGRRLTTIDYSEDRRVDPADIDRALAADPGITHVALVHCETGTGVMNPLHEVAQVVAKH
GRGLIVDAMSSFGAIEIDARTTPFDAVIAASGKCLEGVPGIGFVIAKRSTLERCEGNCHSLAMDLYDQWVYMQRTTQWRF
TPPTHVVAALDAALAQYLDEGGLAARGGRYQRNYRALIDGMRALGFRPFLDPAIQAPIIVTFHAPDDPNYDFKTFYQEVK
KRGYILYPGKLTQVETFRVGCIGHFGEAGIPGAVAAIADTLKAMGVQRMSAEAAA

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=348, Percent_Identity=24.4252873563218, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536281, Length=345, Percent_Identity=24.3478260869565, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 40904; Mature: 40773

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLADQPILLTPGPLTTSARTRDAMLRDWGSWDSDFNAITARLRTRLVQIVHGEETHECV
CCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
PLQGSGTFSVEAAIGTLVPRDGHVLVPNNGAYCQRIAKICRVLGRRLTTIDYSEDRRVDP
EECCCCCEEEEEHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCH
ADIDRALAADPGITHVALVHCETGTGVMNPLHEVAQVVAKHGRGLIVDAMSSFGAIEIDA
HHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEHHHHCCEEEECC
RTTPFDAVIAASGKCLEGVPGIGFVIAKRSTLERCEGNCHSLAMDLYDQWVYMQRTTQWR
CCCCCHHHEECCCCHHCCCCCCEEEEECHHHHHHHCCCHHHHHHHHHHHHHEEEECCCEE
FTPPTHVVAALDAALAQYLDEGGLAARGGRYQRNYRALIDGMRALGFRPFLDPAIQAPII
ECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHCCCCEE
VTFHAPDDPNYDFKTFYQEVKKRGYILYPGKLTQVETFRVGCIGHFGEAGIPGAVAAIAD
EEEECCCCCCCCHHHHHHHHHHCCEEEECCCCCEEEEEEEEEEECCCCCCCCHHHHHHHH
TLKAMGVQRMSAEAAA
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLADQPILLTPGPLTTSARTRDAMLRDWGSWDSDFNAITARLRTRLVQIVHGEETHECV
CCCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
PLQGSGTFSVEAAIGTLVPRDGHVLVPNNGAYCQRIAKICRVLGRRLTTIDYSEDRRVDP
EECCCCCEEEEEHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCH
ADIDRALAADPGITHVALVHCETGTGVMNPLHEVAQVVAKHGRGLIVDAMSSFGAIEIDA
HHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEHHHHCCEEEECC
RTTPFDAVIAASGKCLEGVPGIGFVIAKRSTLERCEGNCHSLAMDLYDQWVYMQRTTQWR
CCCCCHHHEECCCCHHCCCCCCEEEEECHHHHHHHCCCHHHHHHHHHHHHHEEEECCCEE
FTPPTHVVAALDAALAQYLDEGGLAARGGRYQRNYRALIDGMRALGFRPFLDPAIQAPII
ECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHCCCCEE
VTFHAPDDPNYDFKTFYQEVKKRGYILYPGKLTQVETFRVGCIGHFGEAGIPGAVAAIAD
EEEECCCCCCCCHHHHHHHHHHCCEEEECCCCCEEEEEEEEEEECCCCCCCCHHHHHHHH
TLKAMGVQRMSAEAAA
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA