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The map label for this gene is yhdG [H]

Identifier: 161526222

GI number: 161526222

Start: 3336312

End: 3337712

Strand: Direct

Name: yhdG [H]

Synonym: Bmul_3053

Alternate gene names: 161526222

Gene position: 3336312-3337712 (Clockwise)

Preceding gene: 161526221

Following gene: 161526223

Centisome position: 96.75

GC content: 67.45

Gene sequence:

>1401_bases
ATGTCTCTCTTTCGCAAGAAAAACGTCGATCGCATGATCGCCGGCGCGCACGCCGCCGGACTCAAGAAGGCGCTCGGCGC
GATCGACCTGACCTTCCTCGGCATCGGCGCGATCATCGGCACCGGCATCTTCGTGCTGACCGGCACCGGCGCCGTGCAGG
CCGGCCCCGCCCTGATGCTGTCGTTCGTGATCGCCGCGATCGCCTGCGGCCTCGCCGCGCTGTCGTACGCGGAGTTCGCG
TCGACGATCCCGGTCGCCGGCTCGATCTACACGTATTCGTATGCGACGCTCGGCGAACTCGTCGCGTGGATCATCGGCTG
GGACCTGATGCTCGAATACGGGCTCGCGGCATCGGCCGTGTCGGTCGGCTGGTCGGGCTATCTGCAGTCGCTGCTGCAGG
GCTTCGGGCTCACGCTGCCGACCGTGCTGACCGCCGCGCCGGGCGCGGTGCCGGGCGTCGTCACGTGGTTCAACCTGCCC
GCCTTCCTCGTGATGATCGTGATCACGACGCTGCTGTCGATCGGGATCCGCGAATCGACGCGCATCAACAACGTGATGGT
GTTCATCAAGGTCTCGGTCGTGCTGCTCGTGATCGCGGTCGGCCTGTTCCACGTGACGCCCGCGAACTGGAAGCCGTTCA
TGCCGCACGGCTGGAACGGCGTGTTCGGCGCGGCCGCCGTGATGTTCTTCGCGTTCATCGGCTTCGACGCGGTGTCGTCC
GCGGCCGAGGAAGTGAAGAATCCGAAGCGCGACCTGCCGATCGGCATCATCGCGTCGCTCGCGGTGTGCGCGGTGCTCTA
CGTGACGGTCGCGGCGGTCGCGACCGGCATCGTGCCGTCCGCGCAGTACGCGAGCATCTCGCACCCGATCTCGTACGCGC
TGCAGGTCGCGGGCGAGAAATGGGTCGCCGGCTTCATCGATCTCGGCGCGGTGCTCGGCATGCTGACCGTGATTCTCGTG
ATGAGCTACGGGCAGACGCGGATCATCTTCGCGATGTCGCGCGACGGGCTGCTGCCGGGCACGCTGTCGCGCGTGCATCC
GCGTTACGCGACGCCGTTCCTGACGACCTGGCTCGTCGGCCTGTTCTTCGGCCTGATCGCCGCGCTCGTGCCGCTGAACG
TGCTCGCGGAGCTGATCAACATCGGCACGCTCGCCGCGTTCTCGATGGTGTCGATCGCGGTGCTCGTGCTGCGCCGCACG
CACCCGCACCTGCCGCGCGCGTTCCGCTGCCCGGGCGTGCCCGTGGTGCCGCTGCTCGCGGTCGCGGCGTGCGTGTTCCT
GATGGTGAACCTGCAGCCGGTCACCTGGATCGCGTTCGGCGTGTGGCTCGTGATCGGTCTCGCCGTCTATTTTCTCTATT
CGCGACACCATTCGAAGCTCGCCCGCGGCCACGCGGAGTGA

Upstream 100 bases:

>100_bases
TGCGCGCGCACGAGCCTTTTGCGTCAAATCGGCTAAAATTGCGGGTTTTCACTCAGTCAGCAGCGCCGCCCCCGCGCGCC
CCGCTGACGATCCACCCGCA

Downstream 100 bases:

>100_bases
GCCCGCGCGCGGCGCAGCGACGCGCCGCCCGCACCGACGGCGCGCCCGCCTTGCGAGCGCGCCGTTTTGTTTTGCAGCCG
CCGCCGCACGCGCGCGGCAC

Product: amino acid permease-associated protein

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSLFRKKNVDRMIAGAHAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFA
STIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAVSVGWSGYLQSLLQGFGLTLPTVLTAAPGAVPGVVTWFNLP
AFLVMIVITTLLSIGIRESTRINNVMVFIKVSVVLLVIAVGLFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
AAEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPSAQYASISHPISYALQVAGEKWVAGFIDLGAVLGMLTVILV
MSYGQTRIIFAMSRDGLLPGTLSRVHPRYATPFLTTWLVGLFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRT
HPHLPRAFRCPGVPVVPLLAVAACVFLMVNLQPVTWIAFGVWLVIGLAVYFLYSRHHSKLARGHAE

Sequences:

>Translated_466_residues
MSLFRKKNVDRMIAGAHAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFA
STIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAVSVGWSGYLQSLLQGFGLTLPTVLTAAPGAVPGVVTWFNLP
AFLVMIVITTLLSIGIRESTRINNVMVFIKVSVVLLVIAVGLFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
AAEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPSAQYASISHPISYALQVAGEKWVAGFIDLGAVLGMLTVILV
MSYGQTRIIFAMSRDGLLPGTLSRVHPRYATPFLTTWLVGLFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRT
HPHLPRAFRCPGVPVVPLLAVAACVFLMVNLQPVTWIAFGVWLVIGLAVYFLYSRHHSKLARGHAE
>Mature_465_residues
SLFRKKNVDRMIAGAHAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFAS
TIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAVSVGWSGYLQSLLQGFGLTLPTVLTAAPGAVPGVVTWFNLPA
FLVMIVITTLLSIGIRESTRINNVMVFIKVSVVLLVIAVGLFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSSA
AEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPSAQYASISHPISYALQVAGEKWVAGFIDLGAVLGMLTVILVM
SYGQTRIIFAMSRDGLLPGTLSRVHPRYATPFLTTWLVGLFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRTH
PHLPRAFRCPGVPVVPLLAVAACVFLMVNLQPVTWIAFGVWLVIGLAVYFLYSRHHSKLARGHAE

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of The Aromatic Amino Acids (Phenylalanine, Tyrosine, And Tryptophan). [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=410, Percent_Identity=35.609756097561, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI258614003, Length=426, Percent_Identity=33.5680751173709, Blast_Score=216, Evalue=5e-56,
Organism=Homo sapiens, GI258614005, Length=426, Percent_Identity=33.5680751173709, Blast_Score=216, Evalue=5e-56,
Organism=Homo sapiens, GI258645169, Length=426, Percent_Identity=34.5070422535211, Blast_Score=216, Evalue=5e-56,
Organism=Homo sapiens, GI4507047, Length=438, Percent_Identity=34.4748858447489, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI110347453, Length=385, Percent_Identity=35.8441558441558, Blast_Score=202, Evalue=7e-52,
Organism=Homo sapiens, GI114326544, Length=433, Percent_Identity=32.5635103926097, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI114326550, Length=433, Percent_Identity=32.5635103926097, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI187423910, Length=495, Percent_Identity=26.2626262626263, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI7657591, Length=495, Percent_Identity=26.2626262626263, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI115648063, Length=413, Percent_Identity=24.6973365617433, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI115648022, Length=413, Percent_Identity=24.6973365617433, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI186910308, Length=413, Percent_Identity=25.4237288135593, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI186910306, Length=413, Percent_Identity=25.4237288135593, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI186910304, Length=413, Percent_Identity=25.4237288135593, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI33286428, Length=485, Percent_Identity=25.7731958762887, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI7657683, Length=402, Percent_Identity=24.3781094527363, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI71979932, Length=446, Percent_Identity=26.2331838565022, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI9790235, Length=299, Percent_Identity=24.0802675585284, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1786302, Length=478, Percent_Identity=23.0125523012552, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082023, Length=449, Percent_Identity=24.2761692650334, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87081915, Length=432, Percent_Identity=24.0740740740741, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786789, Length=352, Percent_Identity=23.2954545454545, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786602, Length=476, Percent_Identity=23.5294117647059, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081869, Length=460, Percent_Identity=23.4782608695652, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081708, Length=488, Percent_Identity=21.7213114754098, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788480, Length=446, Percent_Identity=24.6636771300448, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367353, Length=468, Percent_Identity=25, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786694, Length=253, Percent_Identity=24.901185770751, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790653, Length=477, Percent_Identity=22.2222222222222, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082250, Length=423, Percent_Identity=23.1678486997636, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=412, Percent_Identity=36.1650485436893, Blast_Score=242, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17533459, Length=415, Percent_Identity=35.421686746988, Blast_Score=219, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17531343, Length=406, Percent_Identity=34.4827586206897, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17540018, Length=433, Percent_Identity=25.1732101616628, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17568033, Length=414, Percent_Identity=24.1545893719807, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193208714, Length=429, Percent_Identity=26.8065268065268, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32566695, Length=429, Percent_Identity=26.8065268065268, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537453, Length=326, Percent_Identity=25.7668711656442, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71982612, Length=410, Percent_Identity=22.1951219512195, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI32566699, Length=374, Percent_Identity=25.668449197861, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71982608, Length=410, Percent_Identity=22.1951219512195, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319991, Length=354, Percent_Identity=27.4011299435028, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24666159, Length=410, Percent_Identity=39.0243902439024, Blast_Score=275, Evalue=7e-74,
Organism=Drosophila melanogaster, GI221512776, Length=410, Percent_Identity=39.0243902439024, Blast_Score=275, Evalue=7e-74,
Organism=Drosophila melanogaster, GI24667468, Length=406, Percent_Identity=35.7142857142857, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24668806, Length=429, Percent_Identity=33.5664335664336, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI21356285, Length=429, Percent_Identity=33.5664335664336, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24668802, Length=429, Percent_Identity=33.5664335664336, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI161077963, Length=425, Percent_Identity=35.7647058823529, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI281366235, Length=413, Percent_Identity=34.6246973365617, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI116007820, Length=413, Percent_Identity=34.6246973365617, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=34.3825665859564, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=34.3825665859564, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI21357367, Length=426, Percent_Identity=28.4037558685446, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24651635, Length=419, Percent_Identity=24.582338902148, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24651633, Length=419, Percent_Identity=24.582338902148, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221331183, Length=474, Percent_Identity=23.4177215189873, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17647653, Length=474, Percent_Identity=23.4177215189873, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24664379, Length=474, Percent_Identity=23.4177215189873, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24641995, Length=410, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641993, Length=410, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550968, Length=466, Percent_Identity=22.9613733905579, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19921172, Length=466, Percent_Identity=22.9613733905579, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49267; Mature: 49136

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFRKKNVDRMIAGAHAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALML
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHCCHHHHH
SFVIAAIACGLAALSYAEFASTIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVGWSGYLQSLLQGFGLTLPTVLTAAPGAVPGVVTWFNLPAFLVMIVITTLLSIGIREST
HHCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RINNVMVFIKVSVVLLVIAVGLFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPSAQYASISHPISYALQVAGEK
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHH
WVAGFIDLGAVLGMLTVILVMSYGQTRIIFAMSRDGLLPGTLSRVHPRYATPFLTTWLVG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHCCCCCCCHHHHHHHHH
LFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRTHPHLPRAFRCPGVPVVPLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
VAACVFLMVNLQPVTWIAFGVWLVIGLAVYFLYSRHHSKLARGHAE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLFRKKNVDRMIAGAHAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALML
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHCCHHHHH
SFVIAAIACGLAALSYAEFASTIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVGWSGYLQSLLQGFGLTLPTVLTAAPGAVPGVVTWFNLPAFLVMIVITTLLSIGIREST
HHCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RINNVMVFIKVSVVLLVIAVGLFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPSAQYASISHPISYALQVAGEK
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHH
WVAGFIDLGAVLGMLTVILVMSYGQTRIIFAMSRDGLLPGTLSRVHPRYATPFLTTWLVG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHCCCCCCCHHHHHHHHH
LFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRTHPHLPRAFRCPGVPVVPLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
VAACVFLMVNLQPVTWIAFGVWLVIGLAVYFLYSRHHSKLARGHAE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]