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The map label for this gene is lrhA [H]

Identifier: 161526111

GI number: 161526111

Start: 3219740

End: 3220765

Strand: Reverse

Name: lrhA [H]

Synonym: Bmul_2942

Alternate gene names: 161526111

Gene position: 3220765-3219740 (Counterclockwise)

Preceding gene: 161526113

Following gene: 161526109

Centisome position: 93.4

GC content: 73.68

Gene sequence:

>1026_bases
ATGACCGAACACGAACACGCCATCGAGTCGCGCGGCGACACGACGCTCGCGCAACCGAACTTCGACATCGCGGCGTTGCG
CAGCCTGGTCGCGGGCGTCGATCTCGGCAGCTTCGCGAAGGCGGCTGACCGCGTCGCGCGCTCGACGTCGGCCGTCAGTG
CGCAGATCCGCAAGCTCGAAGAGCAGGCGGGCACGCCGCTGTTCGTGAAGGCCGGCCGCGGGCTCGCGCTGACCGACGCG
GGCGAGGCGATGCTGCGCTATGCGCGGCGGATCGTCGAGCTGAACGACGAGGCGGCCGCGGCCGTGCGCGGCGTGAACCT
CGACGGCCGCGTGCGCGTGGGCCTGCAGGAGGATTTCGGCGAGGCGATCCTGCCGGACGTGCTCGGCCGCTTTGCACGCG
CGCATCCCAAGGTGCGGATCGACGCGCGCGTATCGCGCAATGCCGATCTGTTCGACCGGCTCGAGGCGAACCAGCTCGAT
CTCGCGCTCGTGTGGGGCGATCCGGCGTCGGCGGAGCGTGCGTCGCGGCCGGGAATCGACAGCGAGACGATCGCGCACGT
CCCGATGCGGTGGATCGGCGCCGCCCATGCGACTCAACCCGAGTTCGACGGCGGCGCGGTGCCAGGCGCGCAGGATCGAG
CCGGCCCGCGTGCGATCGCGGCGACACCCGAGCCGTTGCCGCTCGTGATGTTCGACCGGCCCTGCCGGTTCTTCGGCGCG
GCGACCGATGCGCTCGACCGAGCCGGCGTGCCGTGGCGCGTCGCATTTACGACGCCGAGCCTCGCCGGGCTGTGGGCGGC
CGCCGCGGCCGGCCTCGGGCTGACCGTGCGTTCGCACTACGGGCTGCCGGCGTCGGTGCGCGTGCTCGACGCGGCCGCCT
GCGGCCTGCCCGCGCTGCCGAGCGTGCCGCTCGTGCTGCTGCGGCGCACGTCGTCGGCGACGCCGACCGTCGATCGGCTC
GCGCGGATCGTCACGCAGGCCGTGCGCGAAGCGACACATCCGGCGGCGGCCGCACTCGCCGCGTAG

Upstream 100 bases:

>100_bases
AGACCGGGACGGAAATTGACAGTCACAGTGTCGTCGCCTACATTCATCCTGAAAATCGGAAAGTTTTTGACGGATCGTTC
GATAAAACAGGATGGTCGAC

Downstream 100 bases:

>100_bases
CGTGCAGCGGCGAGCGCGCACGGCGCCTCGCCGATTCGATGCGCGCCGCGCCGCGCTACGCCATCGCGCTCGCCGGCGCA
TGCGCGTCGAGTTCCGCGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTEHEHAIESRGDTTLAQPNFDIAALRSLVAGVDLGSFAKAADRVARSTSAVSAQIRKLEEQAGTPLFVKAGRGLALTDA
GEAMLRYARRIVELNDEAAAAVRGVNLDGRVRVGLQEDFGEAILPDVLGRFARAHPKVRIDARVSRNADLFDRLEANQLD
LALVWGDPASAERASRPGIDSETIAHVPMRWIGAAHATQPEFDGGAVPGAQDRAGPRAIAATPEPLPLVMFDRPCRFFGA
ATDALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSHYGLPASVRVLDAAACGLPALPSVPLVLLRRTSSATPTVDRL
ARIVTQAVREATHPAAAALAA

Sequences:

>Translated_341_residues
MTEHEHAIESRGDTTLAQPNFDIAALRSLVAGVDLGSFAKAADRVARSTSAVSAQIRKLEEQAGTPLFVKAGRGLALTDA
GEAMLRYARRIVELNDEAAAAVRGVNLDGRVRVGLQEDFGEAILPDVLGRFARAHPKVRIDARVSRNADLFDRLEANQLD
LALVWGDPASAERASRPGIDSETIAHVPMRWIGAAHATQPEFDGGAVPGAQDRAGPRAIAATPEPLPLVMFDRPCRFFGA
ATDALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSHYGLPASVRVLDAAACGLPALPSVPLVLLRRTSSATPTVDRL
ARIVTQAVREATHPAAAALAA
>Mature_340_residues
TEHEHAIESRGDTTLAQPNFDIAALRSLVAGVDLGSFAKAADRVARSTSAVSAQIRKLEEQAGTPLFVKAGRGLALTDAG
EAMLRYARRIVELNDEAAAAVRGVNLDGRVRVGLQEDFGEAILPDVLGRFARAHPKVRIDARVSRNADLFDRLEANQLDL
ALVWGDPASAERASRPGIDSETIAHVPMRWIGAAHATQPEFDGGAVPGAQDRAGPRAIAATPEPLPLVMFDRPCRFFGAA
TDALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSHYGLPASVRVLDAAACGLPALPSVPLVLLRRTSSATPTVDRLA
RIVTQAVREATHPAAAALAA

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=315, Percent_Identity=33.015873015873, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787806, Length=144, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787601, Length=144, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI48994962, Length=159, Percent_Identity=28.9308176100629, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI157672245, Length=167, Percent_Identity=28.7425149700599, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786713, Length=89, Percent_Identity=38.2022471910112, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790208, Length=152, Percent_Identity=28.2894736842105, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788481, Length=150, Percent_Identity=28.6666666666667, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788297, Length=185, Percent_Identity=26.4864864864865, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786448, Length=144, Percent_Identity=33.3333333333333, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35893; Mature: 35762

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHEHAIESRGDTTLAQPNFDIAALRSLVAGVDLGSFAKAADRVARSTSAVSAQIRKLE
CCCHHHHHHCCCCCEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQAGTPLFVKAGRGLALTDAGEAMLRYARRIVELNDEAAAAVRGVNLDGRVRVGLQEDFG
HHCCCEEEEECCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEECCHHHCC
EAILPDVLGRFARAHPKVRIDARVSRNADLFDRLEANQLDLALVWGDPASAERASRPGID
HHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCEEEEEEECCCCCHHHCCCCCCC
SETIAHVPMRWIGAAHATQPEFDGGAVPGAQDRAGPRAIAATPEPLPLVMFDRPCRFFGA
CHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCHHHHHH
ATDALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSHYGLPASVRVLDAAACGLPALP
HHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCCCCC
SVPLVLLRRTSSATPTVDRLARIVTQAVREATHPAAAALAA
CCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
TEHEHAIESRGDTTLAQPNFDIAALRSLVAGVDLGSFAKAADRVARSTSAVSAQIRKLE
CCHHHHHHCCCCCEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQAGTPLFVKAGRGLALTDAGEAMLRYARRIVELNDEAAAAVRGVNLDGRVRVGLQEDFG
HHCCCEEEEECCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEECCHHHCC
EAILPDVLGRFARAHPKVRIDARVSRNADLFDRLEANQLDLALVWGDPASAERASRPGID
HHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCEEEEEEECCCCCHHHCCCCCCC
SETIAHVPMRWIGAAHATQPEFDGGAVPGAQDRAGPRAIAATPEPLPLVMFDRPCRFFGA
CHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCHHHHHH
ATDALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSHYGLPASVRVLDAAACGLPALP
HHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCCCCC
SVPLVLLRRTSSATPTVDRLARIVTQAVREATHPAAAALAA
CCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]