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The map label for this gene is gph [C]

Identifier: 161526028

GI number: 161526028

Start: 3123351

End: 3124121

Strand: Direct

Name: gph [C]

Synonym: Bmul_2859

Alternate gene names: 161526028

Gene position: 3123351-3124121 (Clockwise)

Preceding gene: 161526027

Following gene: 161526029

Centisome position: 90.57

GC content: 67.96

Gene sequence:

>771_bases
ATGGCTCAGCCGCCGCTTGCACCGCCCGCATCCGCCGCCGAGCCGCCCGCCGCCGGCGATCGCGCGATCCGCTTGAGCGC
GCCGCGCATCGACGCGGCGCTGATCGATCTGGACGGCACGATGGTCGATACGGTCGACGATTTCACGGCCGGCCTGAACG
CGATGCTCGCGAAGCTCGGTGCGCCGGCCACGTCGCGTGACGAAGTGATCGGCTACGTCGGCAAAGGCTCCGAGCATCTG
ATTCATTGCGTGCTGACGCCGCGCTTCACCGCAGACGAACTGCGCACGCGCTTCGACGACGCGCTCGCGATCTATCAGGC
CGAATACGCGAAGATCAACGGCCGCCACACGCGGCTCTATCCCGACGTCGCGACCGGCCTCGATGCGCTCCGCGCGGCCG
GCATCCGGCTCGCATGCGTGACGAACAAGCCTCACCGCTTCGCGGTCGAGCTGCTCGAGCAATACGGGCTTGCCGATCGA
TTCGGCATCGTGCTCGGCGGCGACAGCGTCGCGCGCAAGAAGCCCGATCCGCTGCCGATGCTGGCGGCCTGCGACGCGCT
CGGCGTCGCGCCGCACGTGTCGGTCGCGATCGGCGACTCGGAAAACGACGCGCTCGCGGGCCGCGCGGCCGGGATGGCGA
CGCTGACGGTCCCGTATGGCTACAACCACGGCAAGCCTATACAAACGATAAATTCGGATGGTATAGTCGATTCGTTGCTG
GTTGCGGCTCGCGCGATCGTCGCGCACAACGCCGGCCAGCCAACCGTCTGA

Upstream 100 bases:

>100_bases
ACGTTCGTCGCGGGCTCCGCGATCTTCGGCAAGCCCGATTACCGAAAGGTGATCGACGAGATGCGCGCCGCCCTCGCGGC
CGTCGAGCGGAGCTGACGCG

Downstream 100 bases:

>100_bases
CTATTTCTTCCATCCGCATGTTTCTGAATAAAAAACGGAGTCTGAGCAGCATCGACCGGGGAGCCTGGCCCTGGCGTCGC
TGGTCGCGCTAACCTCTTCG

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MAQPPLAPPASAAEPPAAGDRAIRLSAPRIDAALIDLDGTMVDTVDDFTAGLNAMLAKLGAPATSRDEVIGYVGKGSEHL
IHCVLTPRFTADELRTRFDDALAIYQAEYAKINGRHTRLYPDVATGLDALRAAGIRLACVTNKPHRFAVELLEQYGLADR
FGIVLGGDSVARKKPDPLPMLAACDALGVAPHVSVAIGDSENDALAGRAAGMATLTVPYGYNHGKPIQTINSDGIVDSLL
VAARAIVAHNAGQPTV

Sequences:

>Translated_256_residues
MAQPPLAPPASAAEPPAAGDRAIRLSAPRIDAALIDLDGTMVDTVDDFTAGLNAMLAKLGAPATSRDEVIGYVGKGSEHL
IHCVLTPRFTADELRTRFDDALAIYQAEYAKINGRHTRLYPDVATGLDALRAAGIRLACVTNKPHRFAVELLEQYGLADR
FGIVLGGDSVARKKPDPLPMLAACDALGVAPHVSVAIGDSENDALAGRAAGMATLTVPYGYNHGKPIQTINSDGIVDSLL
VAARAIVAHNAGQPTV
>Mature_255_residues
AQPPLAPPASAAEPPAAGDRAIRLSAPRIDAALIDLDGTMVDTVDDFTAGLNAMLAKLGAPATSRDEVIGYVGKGSEHLI
HCVLTPRFTADELRTRFDDALAIYQAEYAKINGRHTRLYPDVATGLDALRAAGIRLACVTNKPHRFAVELLEQYGLADRF
GIVLGGDSVARKKPDPLPMLAACDALGVAPHVSVAIGDSENDALAGRAAGMATLTVPYGYNHGKPIQTINSDGIVDSLLV
AARAIVAHNAGQPTV

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=223, Percent_Identity=34.5291479820628, Blast_Score=124, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR000150
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 26748; Mature: 26617

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPPLAPPASAAEPPAAGDRAIRLSAPRIDAALIDLDGTMVDTVDDFTAGLNAMLAKLG
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHC
APATSRDEVIGYVGKGSEHLIHCVLTPRFTADELRTRFDDALAIYQAEYAKINGRHTRLY
CCCCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEECCCEEEEC
PDVATGLDALRAAGIRLACVTNKPHRFAVELLEQYGLADRFGIVLGGDSVARKKPDPLPM
CHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCHHCEEEECCCHHHCCCCCCCCH
LAACDALGVAPHVSVAIGDSENDALAGRAAGMATLTVPYGYNHGKPIQTINSDGIVDSLL
HHHHHHCCCCCCEEEEECCCCCCCHHHHCCCEEEEEEECCCCCCCCCEEECCCCHHHHHH
VAARAIVAHNAGQPTV
HHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AQPPLAPPASAAEPPAAGDRAIRLSAPRIDAALIDLDGTMVDTVDDFTAGLNAMLAKLG
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHC
APATSRDEVIGYVGKGSEHLIHCVLTPRFTADELRTRFDDALAIYQAEYAKINGRHTRLY
CCCCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEECCCEEEEC
PDVATGLDALRAAGIRLACVTNKPHRFAVELLEQYGLADRFGIVLGGDSVARKKPDPLPM
CHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCHHCEEEECCCHHHCCCCCCCCH
LAACDALGVAPHVSVAIGDSENDALAGRAAGMATLTVPYGYNHGKPIQTINSDGIVDSLL
HHHHHHCCCCCCEEEEECCCCCCCHHHHCCCEEEEEEECCCCCCCCCEEECCCCHHHHHH
VAARAIVAHNAGQPTV
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA