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The map label for this gene is pilC [H]

Identifier: 161525988

GI number: 161525988

Start: 3071857

End: 3073074

Strand: Direct

Name: pilC [H]

Synonym: Bmul_2819

Alternate gene names: 161525988

Gene position: 3071857-3073074 (Clockwise)

Preceding gene: 161525987

Following gene: 161525989

Centisome position: 89.08

GC content: 73.73

Gene sequence:

>1218_bases
ATGACTATGACCATGCGCGCGCGGCCTCGCGAGATGCGCTTTGCCTGGCGCGGCCGTCGCCGCGACGGCACGCCGCGCAG
CGGTACCGTCGTCGCATTCGACGCCGCAGCAGCGCGCGCCGCGCTCGCGCGCGACGGCATCGCGGTGCTGTCGCTCGACG
CGCGCGGGCCGGCGAAGCCGCCGACGGCGCGTGCCCGCGACGTCACGCGCTTCACCCGTCAGCTCGCGAGCCTGCTGCAG
GCCGGCCTGCCGCTCGCGCCGGCGCTCGACATGCTGTCGCGCACGCGCACGCACGGCGGTCTGCCGCGCATCGCTGCCGG
CCTCGCGCGCGAAATCGTCGACGGGCAGCGCTTCGCGGCCGCGCTTGCGCTGTACCCGTCGCAGTTCGGCACGCTGTATC
GGCAGCTGATCGAGGTCGGCGAAGCGTCGGGCGCGCTCGGCACGGTGCTGATGCGCATCGCCGAGCATCGCGAACGCGCG
GACGCGCAATGGCGCAAGCTGCGCGCGGCGCTCGCCTATCCGGCCGTCGTGATCCTGTTTGCGCTCGCGATCGCGGCCGC
GCTGATGGTGTGGGTCGTGCCGACCTTCCGGCAGATCTTCGACGGTTTCGGCACCGCCCTGCCGGCGCCGACACGTGCGC
TGCTCGCGCTCTCGTCCGCGCTGTCGGCATCGGGCGGCGCGCTGGCCGCCGGCGCCGCCGCAGCCGCGCTCGCTGCACAC
CACGCGCTGCGGCGCTCGCCGACGCTGCGATACGCGCTCGCGCGGCAGGCGTTGCGCGCGCCGCTCATCGGCGACACGCT
GACGCGATACGCGGCCGCGCGCTGGTGCCGCTCGCTCGCGACGCTGCTGGGCGCCGGCGTGCCGCTCGCCGACGCATTCG
CGACGCTCGAGCGAACGGCCGGCCACCACGTGTTCGAACGGGCGAGCACGCAGATCGCCGCGCGCGTGCTGCGCGGCGCA
CGCCTGGCCGACGCGATGCAGGCGAGCGGCTGCTTCCCCGACGACATCGTGCAGCCGATCGCCGTCGCCGAAGAAACCGG
CGCGCTCGACACGATGCTCGCCGACATCGCGACGCTGTCCGAACATCAACTCGATGCGCGCATCGACACGCTTGCCGCGC
TCGGCGAACCGCTGATCGTGATCGTGCTCGGCGCGCTCGTCGGCGGGCTCGTGATCGCGATGTATCTGCCGATCCTTCAG
CTCGGCAACGTGGTGTAG

Upstream 100 bases:

>100_bases
CGGCGGCGGAAGGCGTTCGCACTTTGCGTGACGCGGCGCTCGCGCGCGTTCGAGACGGCACGACGAGCGTCGCGGAAGCG
CTCGCCGCCACGCCGAACGC

Downstream 100 bases:

>100_bases
CATCGCAGCGCACTATCGCCCTTTTTGTCGGAACCCTTCAGCATCATGACGCCCGCGCCCCTGTACGCCGCCTCTTCTGC
GCCCGAGAGCACGCTGCTCG

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTMTMRARPREMRFAWRGRRRDGTPRSGTVVAFDAAAARAALARDGIAVLSLDARGPAKPPTARARDVTRFTRQLASLLQ
AGLPLAPALDMLSRTRTHGGLPRIAAGLAREIVDGQRFAAALALYPSQFGTLYRQLIEVGEASGALGTVLMRIAEHRERA
DAQWRKLRAALAYPAVVILFALAIAAALMVWVVPTFRQIFDGFGTALPAPTRALLALSSALSASGGALAAGAAAAALAAH
HALRRSPTLRYALARQALRAPLIGDTLTRYAAARWCRSLATLLGAGVPLADAFATLERTAGHHVFERASTQIAARVLRGA
RLADAMQASGCFPDDIVQPIAVAEETGALDTMLADIATLSEHQLDARIDTLAALGEPLIVIVLGALVGGLVIAMYLPILQ
LGNVV

Sequences:

>Translated_405_residues
MTMTMRARPREMRFAWRGRRRDGTPRSGTVVAFDAAAARAALARDGIAVLSLDARGPAKPPTARARDVTRFTRQLASLLQ
AGLPLAPALDMLSRTRTHGGLPRIAAGLAREIVDGQRFAAALALYPSQFGTLYRQLIEVGEASGALGTVLMRIAEHRERA
DAQWRKLRAALAYPAVVILFALAIAAALMVWVVPTFRQIFDGFGTALPAPTRALLALSSALSASGGALAAGAAAAALAAH
HALRRSPTLRYALARQALRAPLIGDTLTRYAAARWCRSLATLLGAGVPLADAFATLERTAGHHVFERASTQIAARVLRGA
RLADAMQASGCFPDDIVQPIAVAEETGALDTMLADIATLSEHQLDARIDTLAALGEPLIVIVLGALVGGLVIAMYLPILQ
LGNVV
>Mature_404_residues
TMTMRARPREMRFAWRGRRRDGTPRSGTVVAFDAAAARAALARDGIAVLSLDARGPAKPPTARARDVTRFTRQLASLLQA
GLPLAPALDMLSRTRTHGGLPRIAAGLAREIVDGQRFAAALALYPSQFGTLYRQLIEVGEASGALGTVLMRIAEHRERAD
AQWRKLRAALAYPAVVILFALAIAAALMVWVVPTFRQIFDGFGTALPAPTRALLALSSALSASGGALAAGAAAAALAAHH
ALRRSPTLRYALARQALRAPLIGDTLTRYAAARWCRSLATLLGAGVPLADAFATLERTAGHHVFERASTQIAARVLRGAR
LADAMQASGCFPDDIVQPIAVAEETGALDTMLADIATLSEHQLDARIDTLAALGEPLIVIVLGALVGGLVIAMYLPILQL
GNVV

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=398, Percent_Identity=28.391959798995, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1786295, Length=388, Percent_Identity=28.0927835051546, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 42742; Mature: 42611

Theoretical pI: Translated: 11.57; Mature: 11.57

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTMRARPREMRFAWRGRRRDGTPRSGTVVAFDAAAARAALARDGIAVLSLDARGPAKP
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEECCCCCCCC
PTARARDVTRFTRQLASLLQAGLPLAPALDMLSRTRTHGGLPRIAAGLAREIVDGQRFAA
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALALYPSQFGTLYRQLIEVGEASGALGTVLMRIAEHRERADAQWRKLRAALAYPAVVILF
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAIAAALMVWVVPTFRQIFDGFGTALPAPTRALLALSSALSASGGALAAGAAAAALAAH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
HALRRSPTLRYALARQALRAPLIGDTLTRYAAARWCRSLATLLGAGVPLADAFATLERTA
HHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GHHVFERASTQIAARVLRGARLADAMQASGCFPDDIVQPIAVAEETGALDTMLADIATLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
EHQLDARIDTLAALGEPLIVIVLGALVGGLVIAMYLPILQLGNVV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TMTMRARPREMRFAWRGRRRDGTPRSGTVVAFDAAAARAALARDGIAVLSLDARGPAKP
CCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEECCCCCCCC
PTARARDVTRFTRQLASLLQAGLPLAPALDMLSRTRTHGGLPRIAAGLAREIVDGQRFAA
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALALYPSQFGTLYRQLIEVGEASGALGTVLMRIAEHRERADAQWRKLRAALAYPAVVILF
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAIAAALMVWVVPTFRQIFDGFGTALPAPTRALLALSSALSASGGALAAGAAAAALAAH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
HALRRSPTLRYALARQALRAPLIGDTLTRYAAARWCRSLATLLGAGVPLADAFATLERTA
HHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GHHVFERASTQIAARVLRGARLADAMQASGCFPDDIVQPIAVAEETGALDTMLADIATLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
EHQLDARIDTLAALGEPLIVIVLGALVGGLVIAMYLPILQLGNVV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]