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The map label for this gene is paaG [C]

Identifier: 161525914

GI number: 161525914

Start: 2996970

End: 2997746

Strand: Direct

Name: paaG [C]

Synonym: Bmul_2745

Alternate gene names: 161525914

Gene position: 2996970-2997746 (Clockwise)

Preceding gene: 161525912

Following gene: 161525918

Centisome position: 86.91

GC content: 61.78

Gene sequence:

>777_bases
ATGACTGCCCAAATTCACGTGGATCAGGCCGACGGCATTCTGACGATGACGCTTGCCCGACCGGACAAGAAGAATGCGCT
GACGAATGAGATGTATGGCAGGTTGGCAGACGTCATTGAGCACGCCGAGCATGACGGCCAAACGCGCGTGTTGTTGCTGC
AAGCGGACGGAGACATGTTTACCGCGGGCAACGACGTGGGCGAATTCGCCGCCATCGCGTCGGGCAAGGGGCCAAGCGAG
CGACATGTCCATCGCTTCCTGCATGCGCTGGCGAAGTCGAACCTGCCCGTCATTGCCGCGGTCCAGGGCAAGGCAGTCGG
TATCGGAACCACGATGCTCCTCCACTGCGACTACGTGCTGCTCGCGCCGGAAGCCGAGCTGATCACCCCGTTCGTCAATC
TTGCGCTTGTCCCGGAAGCGGCATCCAGCTACCTGCTTCCGCTGCGCGTCGGCCATCTGCGGGCCTTCGAGATGTTTGCG
CTCGGCGAGCCGCTCGACGCGCAAACCGCGGTCGCATGGGGTCTTGCCAACAAGGTGTGCGCGAAGGAGCAACTACGCCT
CGATGCGCGCAGGATGGCCGAAAGAATCGCCGCCAAGCCGGCCGGCTCGTTGAGCGCCACCAAAAAGCTGATGCGCGAAG
CCCAGAAGCTGATCGCGCAAATGGACAGCGAGAGCGCGATGTTTCAGGAGCGACTGACGAGCGCCGAGGCAAGAGAAGCA
TTCGCGGCCTTTGCGGAAAAACGCAAACCGAATTTCGCCGCGGTTACGCAACAGTAA

Upstream 100 bases:

>100_bases
AACGAAATTCCAACGAAATTCCGGCCGTCGGATCTCAGGTTTACTTCGCACGCGAACTTCTCATATACTTCACATGCGAA
CCAAACCTGTGGAGAACACC

Downstream 100 bases:

>100_bases
CCGACAGCTCACTGCCCAGCCACGGATCAGGCTACGTATCGCCCTCTTCGGCGAGCGGAAACTTGGTCTGAAGGCTGGTC
AGCCAGCGCGCCACGACGTC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTAQIHVDQADGILTMTLARPDKKNALTNEMYGRLADVIEHAEHDGQTRVLLLQADGDMFTAGNDVGEFAAIASGKGPSE
RHVHRFLHALAKSNLPVIAAVQGKAVGIGTTMLLHCDYVLLAPEAELITPFVNLALVPEAASSYLLPLRVGHLRAFEMFA
LGEPLDAQTAVAWGLANKVCAKEQLRLDARRMAERIAAKPAGSLSATKKLMREAQKLIAQMDSESAMFQERLTSAEAREA
FAAFAEKRKPNFAAVTQQ

Sequences:

>Translated_258_residues
MTAQIHVDQADGILTMTLARPDKKNALTNEMYGRLADVIEHAEHDGQTRVLLLQADGDMFTAGNDVGEFAAIASGKGPSE
RHVHRFLHALAKSNLPVIAAVQGKAVGIGTTMLLHCDYVLLAPEAELITPFVNLALVPEAASSYLLPLRVGHLRAFEMFA
LGEPLDAQTAVAWGLANKVCAKEQLRLDARRMAERIAAKPAGSLSATKKLMREAQKLIAQMDSESAMFQERLTSAEAREA
FAAFAEKRKPNFAAVTQQ
>Mature_257_residues
TAQIHVDQADGILTMTLARPDKKNALTNEMYGRLADVIEHAEHDGQTRVLLLQADGDMFTAGNDVGEFAAIASGKGPSER
HVHRFLHALAKSNLPVIAAVQGKAVGIGTTMLLHCDYVLLAPEAELITPFVNLALVPEAASSYLLPLRVGHLRAFEMFAL
GEPLDAQTAVAWGLANKVCAKEQLRLDARRMAERIAAKPAGSLSATKKLMREAQKLIAQMDSESAMFQERLTSAEAREAF
AAFAEKRKPNFAAVTQQ

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=250, Percent_Identity=31.2, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI260275230, Length=250, Percent_Identity=31.2, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI260274832, Length=250, Percent_Identity=31.2, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI31542718, Length=252, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI194097323, Length=239, Percent_Identity=28.8702928870293, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4757968, Length=256, Percent_Identity=25.390625, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI49355787, Length=256, Percent_Identity=25.390625, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI25453481, Length=256, Percent_Identity=25, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI51538573, Length=256, Percent_Identity=25, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4757966, Length=181, Percent_Identity=28.1767955801105, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI51538581, Length=181, Percent_Identity=28.1767955801105, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI116235487, Length=235, Percent_Identity=25.9574468085106, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI221307494, Length=181, Percent_Identity=27.6243093922652, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI221136756, Length=181, Percent_Identity=27.6243093922652, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI221136753, Length=181, Percent_Identity=27.6243093922652, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4502327, Length=261, Percent_Identity=26.0536398467433, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI68989263, Length=208, Percent_Identity=27.4038461538462, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI70995211, Length=221, Percent_Identity=25.7918552036199, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787660, Length=256, Percent_Identity=33.984375, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=29.1338582677165, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=29.5454545454545, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790281, Length=182, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788597, Length=254, Percent_Identity=24.8031496062992, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI87082183, Length=219, Percent_Identity=26.027397260274, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17535521, Length=253, Percent_Identity=33.596837944664, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI25145438, Length=247, Percent_Identity=29.9595141700405, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17549921, Length=212, Percent_Identity=31.1320754716981, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17554946, Length=253, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=236, Percent_Identity=28.8135593220339, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=204, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540306, Length=241, Percent_Identity=24.896265560166, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17534483, Length=219, Percent_Identity=24.6575342465753, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323314, Length=182, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24654903, Length=250, Percent_Identity=26.8, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI20129971, Length=249, Percent_Identity=28.5140562248996, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24653477, Length=249, Percent_Identity=28.5140562248996, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24653139, Length=253, Percent_Identity=28.8537549407115, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922422, Length=255, Percent_Identity=22.3529411764706, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27943; Mature: 27811

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQIHVDQADGILTMTLARPDKKNALTNEMYGRLADVIEHAEHDGQTRVLLLQADGDMF
CCCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEE
TAGNDVGEFAAIASGKGPSERHVHRFLHALAKSNLPVIAAVQGKAVGIGTTMLLHCDYVL
ECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEECCCEEEHCCCEEE
LAPEAELITPFVNLALVPEAASSYLLPLRVGHLRAFEMFALGEPLDAQTAVAWGLANKVC
ECCCHHHHHHHHHHEECCCCCCCEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AKEQLRLDARRMAERIAAKPAGSLSATKKLMREAQKLIAQMDSESAMFQERLTSAEAREA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FAAFAEKRKPNFAAVTQQ
HHHHHHHCCCCCEECCCC
>Mature Secondary Structure 
TAQIHVDQADGILTMTLARPDKKNALTNEMYGRLADVIEHAEHDGQTRVLLLQADGDMF
CCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEE
TAGNDVGEFAAIASGKGPSERHVHRFLHALAKSNLPVIAAVQGKAVGIGTTMLLHCDYVL
ECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEECCCEEEHCCCEEE
LAPEAELITPFVNLALVPEAASSYLLPLRVGHLRAFEMFALGEPLDAQTAVAWGLANKVC
ECCCHHHHHHHHHHEECCCCCCCEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AKEQLRLDARRMAERIAAKPAGSLSATKKLMREAQKLIAQMDSESAMFQERLTSAEAREA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FAAFAEKRKPNFAAVTQQ
HHHHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA